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The map label for this gene is argB

Identifier: 83594670

GI number: 83594670

Start: 3853155

End: 3854087

Strand: Direct

Name: argB

Synonym: Rru_A3341

Alternate gene names: 83594670

Gene position: 3853155-3854087 (Clockwise)

Preceding gene: 83594669

Following gene: 83594671

Centisome position: 88.52

GC content: 65.17

Gene sequence:

>933_bases
ATGATGACCGATTCTGCGCCCCCGGAGCCGATCCACGCGGAAATCCCCGAAGGATGGCTTCATAAGGCCAAGACCCTGTC
CGAGGCCTTGCCCTATATGCGGCGCTTCGCCGGGTTGACCATCGTCATCAAATACGGCGGTCATGCCATGGGCGACCCCG
AACTGGCCAAGACCTTCGCCCGCGATGTCGTGCTGCTCAAGCAAGTCGGCATGAACCCGGTCGTCGTCCATGGCGGCGGC
CCGCAGATCGGGCGCATGCTTGATACCCTGCGCATCCAGAGCACCTTCATCGACGGCCTGCGCGTCACCGACGCCGCCAC
CGTCGATGTGGTCGAGATGGTCCTGGCCGGCTCGATCAATAAGGCCATCGTCACCGAGATCAATCAGGCCGGGGGCTGCG
CCGTCGGGCTGTCGGGCAAGGACGGCCGGCTGATCCAGGCCCGCAAGATGGTGCGCAAGCGCCACGATCCCGAATCCAAT
ATCGAGCGCGTCCTTGATCTTGGCTTCGTCGGCGAGCCGGTGGTGATCGATCCCCATGTGCTGATCCAGTTCCGCGACTC
CGATATCATCCCGGTGATCGCCCCGATCGGCATCGGCGAGGCCGGCGAGACTTTCAACATCAACGCCGATACCGCCGCCG
GGGCGTTGGCCGCCCAGATGAAGGCGGCGCGGCTGTTGATGCTGACCGACGTCAAAGGCGTTCTCGACAAGGACAAGCAG
CTGATCCAAGAGCTGTCGGTCGATCGCGCCCGCCTGCTCAAGCAAGAGGGCACCATCAGCGGCGGCATGATCCCCAAGGT
GGAGACCTGCATCGACGCCGTCGAACGGGGGGTCGAGGCCGCGGTGATCGTCGATGGCCGGGTGCCCCATGCCGTGCTGC
TGGAGATCTTCACCCCACGCGGCGCCGGCACCCTGATCCGGGCGAGCCGCTAG

Upstream 100 bases:

>100_bases
GCCGTAAGCGGCCCCCGCCCCTCCGCCCAGCGGCCGGCGGATGCCCGGCCGTTTTCTCCGAAAGTCCGGGCTCCCGTCCC
GGACGACGCAAAGGACCCGG

Downstream 100 bases:

>100_bases
AGCGGCGAGCGGAAAAGTGGGTCCCGCTTTTCCGCGCCGTCGCCGCTCTAATTTATAGACTCTCGATCAAATCGTCGCCG
CACTCTGGTCCAGATTGCTC

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MMTDSAPPEPIHAEIPEGWLHKAKTLSEALPYMRRFAGLTIVIKYGGHAMGDPELAKTFARDVVLLKQVGMNPVVVHGGG
PQIGRMLDTLRIQSTFIDGLRVTDAATVDVVEMVLAGSINKAIVTEINQAGGCAVGLSGKDGRLIQARKMVRKRHDPESN
IERVLDLGFVGEPVVIDPHVLIQFRDSDIIPVIAPIGIGEAGETFNINADTAAGALAAQMKAARLLMLTDVKGVLDKDKQ
LIQELSVDRARLLKQEGTISGGMIPKVETCIDAVERGVEAAVIVDGRVPHAVLLEIFTPRGAGTLIRASR

Sequences:

>Translated_310_residues
MMTDSAPPEPIHAEIPEGWLHKAKTLSEALPYMRRFAGLTIVIKYGGHAMGDPELAKTFARDVVLLKQVGMNPVVVHGGG
PQIGRMLDTLRIQSTFIDGLRVTDAATVDVVEMVLAGSINKAIVTEINQAGGCAVGLSGKDGRLIQARKMVRKRHDPESN
IERVLDLGFVGEPVVIDPHVLIQFRDSDIIPVIAPIGIGEAGETFNINADTAAGALAAQMKAARLLMLTDVKGVLDKDKQ
LIQELSVDRARLLKQEGTISGGMIPKVETCIDAVERGVEAAVIVDGRVPHAVLLEIFTPRGAGTLIRASR
>Mature_310_residues
MMTDSAPPEPIHAEIPEGWLHKAKTLSEALPYMRRFAGLTIVIKYGGHAMGDPELAKTFARDVVLLKQVGMNPVVVHGGG
PQIGRMLDTLRIQSTFIDGLRVTDAATVDVVEMVLAGSINKAIVTEINQAGGCAVGLSGKDGRLIQARKMVRKRHDPESN
IERVLDLGFVGEPVVIDPHVLIQFRDSDIIPVIAPIGIGEAGETFNINADTAAGALAAQMKAARLLMLTDVKGVLDKDKQ
LIQELSVDRARLLKQEGTISGGMIPKVETCIDAVERGVEAAVIVDGRVPHAVLLEIFTPRGAGTLIRASR

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI145693208, Length=234, Percent_Identity=31.1965811965812, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789181, Length=300, Percent_Identity=26, Blast_Score=89, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6320913, Length=299, Percent_Identity=27.4247491638796, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGB_RHORT (Q2RP10)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_428422.1
- HSSP:   Q9HTN2
- ProteinModelPortal:   Q2RP10
- SMR:   Q2RP10
- STRING:   Q2RP10
- GeneID:   3836793
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A3341
- NMPDR:   fig|1085.1.peg.2154
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- PhylomeDB:   Q2RP10
- ProtClustDB:   PRK00942
- BioCyc:   RRUB269796:RRU_A3341-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 33191; Mature: 33191

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: BINDING 101-101 BINDING 206-206

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTDSAPPEPIHAEIPEGWLHKAKTLSEALPYMRRFAGLTIVIKYGGHAMGDPELAKTFA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHH
RDVVLLKQVGMNPVVVHGGGPQIGRMLDTLRIQSTFIDGLRVTDAATVDVVEMVLAGSIN
HHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHCCCC
KAIVTEINQAGGCAVGLSGKDGRLIQARKMVRKRHDPESNIERVLDLGFVGEPVVIDPHV
HHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEECCEE
LIQFRDSDIIPVIAPIGIGEAGETFNINADTAAGALAAQMKAARLLMLTDVKGVLDKDKQ
EEEECCCCCCEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHHEEHHHHHHHHHHHH
LIQELSVDRARLLKQEGTISGGMIPKVETCIDAVERGVEAAVIVDGRVPHAVLLEIFTPR
HHHHHCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEHEEECCC
GAGTLIRASR
CCCCEEEECC
>Mature Secondary Structure
MMTDSAPPEPIHAEIPEGWLHKAKTLSEALPYMRRFAGLTIVIKYGGHAMGDPELAKTFA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHH
RDVVLLKQVGMNPVVVHGGGPQIGRMLDTLRIQSTFIDGLRVTDAATVDVVEMVLAGSIN
HHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHCCCC
KAIVTEINQAGGCAVGLSGKDGRLIQARKMVRKRHDPESNIERVLDLGFVGEPVVIDPHV
HHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEECCEE
LIQFRDSDIIPVIAPIGIGEAGETFNINADTAAGALAAQMKAARLLMLTDVKGVLDKDKQ
EEEECCCCCCEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHHEEHHHHHHHHHHHH
LIQELSVDRARLLKQEGTISGGMIPKVETCIDAVERGVEAAVIVDGRVPHAVLLEIFTPR
HHHHHCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEHEEECCC
GAGTLIRASR
CCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA