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The map label for this gene is dapA [H]

Identifier: 83594671

GI number: 83594671

Start: 3854287

End: 3855165

Strand: Direct

Name: dapA [H]

Synonym: Rru_A3342

Alternate gene names: 83594671

Gene position: 3854287-3855165 (Clockwise)

Preceding gene: 83594670

Following gene: 83594672

Centisome position: 88.55

GC content: 49.26

Gene sequence:

>879_bases
ATGAAGAAGCAGGTTTTTATGGGGGCCGCAGTTGCAATCGTAACCCCTTTCCGAGACGGGAAGGTTGATTACCAAAAGCT
ACGTGAGTTGATCGAGTTCCAGATTGCTCACAAGATCGATGCTGTCGTTGTCTGCGGGACAACCGGTGAATCTTCCGCGC
TATCCCACGATGAGCATATTTCCGTGGTGCGGTTTGTAGTTGAGACTGTCAAAAGACGGGTGCCGGTCATAGCGGGAGCC
GGAAGCAACAATACTCAACACGCTGTCGATCTTTCTGTTGAACTGGAAAAAGTGGGTGCAGATGCGTTGCTTTCCGTTGT
GCCCTATTACAATAAGACATCACAACGCGGTTTGGTGACCCATTTCAGTACAATCGCACGAGCTGTCGCAATACCTATTA
TACTGTATAACATTCCGTCCCGGACAAGCTTCAATATGACTCCGGAAACTATTCGCGAGATAGCGGAGAATGAGACTGTA
GTCGGAATTAAGGAATGTAATCTCTATCAAGTTGGCGAAATAGTAAAATTATGCGGCCCAGAATTCTCCATATACTCAGG
GGATGACAGTACCATCCTCCCGGTACTGGCGTATGGTGGTAAAGGCGTTATTTCCACCATGGCCAACATCATTCCCGAAG
AGACGCATGATATTGTTTCCTACTTTATGCGGGGCGACATTGAGGGGGCAAGGCGGGCTCAACTCCGTGCGCTGGATTTG
ATAAGTGCGCTGTTTGTGGATGTGAATCCGATTCCTTTGAAGACGGCTATGAACCTGATGGGGATGAATGTCGGACCGTG
TCGGTTACCTTTGGTGGATATGGGGAACCGTGAGACAGAGCTCTTGGTCCGGGCTCTGAAGGATTACGGACTCACGTGA

Upstream 100 bases:

>100_bases
CGGAATTTACTCGAATTAGTTGTGTTTAAGTTCATTTAATAACTGTGGTTATGGCCACGCGATTACATGAAGGCTGCTTA
AGCGCGGGGGAGAGCGTGTT

Downstream 100 bases:

>100_bases
TGGTGCCGCTTGCGAGCTGCGGATTAAAACTCGACCAAGGGGATGAGATCTGGCTTCGCGCCTCTGAACAGGTCCGTTGA
GAGATCTTTCCGCCTGTGAA

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MKKQVFMGAAVAIVTPFRDGKVDYQKLRELIEFQIAHKIDAVVVCGTTGESSALSHDEHISVVRFVVETVKRRVPVIAGA
GSNNTQHAVDLSVELEKVGADALLSVVPYYNKTSQRGLVTHFSTIARAVAIPIILYNIPSRTSFNMTPETIREIAENETV
VGIKECNLYQVGEIVKLCGPEFSIYSGDDSTILPVLAYGGKGVISTMANIIPEETHDIVSYFMRGDIEGARRAQLRALDL
ISALFVDVNPIPLKTAMNLMGMNVGPCRLPLVDMGNRETELLVRALKDYGLT

Sequences:

>Translated_292_residues
MKKQVFMGAAVAIVTPFRDGKVDYQKLRELIEFQIAHKIDAVVVCGTTGESSALSHDEHISVVRFVVETVKRRVPVIAGA
GSNNTQHAVDLSVELEKVGADALLSVVPYYNKTSQRGLVTHFSTIARAVAIPIILYNIPSRTSFNMTPETIREIAENETV
VGIKECNLYQVGEIVKLCGPEFSIYSGDDSTILPVLAYGGKGVISTMANIIPEETHDIVSYFMRGDIEGARRAQLRALDL
ISALFVDVNPIPLKTAMNLMGMNVGPCRLPLVDMGNRETELLVRALKDYGLT
>Mature_292_residues
MKKQVFMGAAVAIVTPFRDGKVDYQKLRELIEFQIAHKIDAVVVCGTTGESSALSHDEHISVVRFVVETVKRRVPVIAGA
GSNNTQHAVDLSVELEKVGADALLSVVPYYNKTSQRGLVTHFSTIARAVAIPIILYNIPSRTSFNMTPETIREIAENETV
VGIKECNLYQVGEIVKLCGPEFSIYSGDDSTILPVLAYGGKGVISTMANIIPEETHDIVSYFMRGDIEGARRAQLRALDL
ISALFVDVNPIPLKTAMNLMGMNVGPCRLPLVDMGNRETELLVRALKDYGLT

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=287, Percent_Identity=27.8745644599303, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI13540533, Length=283, Percent_Identity=24.3816254416961, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1788823, Length=291, Percent_Identity=39.5189003436426, Blast_Score=205, Evalue=3e-54,
Organism=Escherichia coli, GI87082415, Length=298, Percent_Identity=33.2214765100671, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1786463, Length=236, Percent_Identity=30.5084745762712, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1789620, Length=269, Percent_Identity=29.368029739777, Blast_Score=108, Evalue=6e-25,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31935; Mature: 31935

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00665 DHDPS_1 ; PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQVFMGAAVAIVTPFRDGKVDYQKLRELIEFQIAHKIDAVVVCGTTGESSALSHDEHI
CCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHH
SVVRFVVETVKRRVPVIAGAGSNNTQHAVDLSVELEKVGADALLSVVPYYNKTSQRGLVT
HHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEEEHHHHCHHHHHHHHCCCCCCCCCCHHH
HFSTIARAVAIPIILYNIPSRTSFNMTPETIREIAENETVVGIKECNLYQVGEIVKLCGP
HHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCC
EFSIYSGDDSTILPVLAYGGKGVISTMANIIPEETHDIVSYFMRGDIEGARRAQLRALDL
CCEEECCCCCEEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
ISALFVDVNPIPLKTAMNLMGMNVGPCRLPLVDMGNRETELLVRALKDYGLT
HHHHHHCCCCCCHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKQVFMGAAVAIVTPFRDGKVDYQKLRELIEFQIAHKIDAVVVCGTTGESSALSHDEHI
CCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHH
SVVRFVVETVKRRVPVIAGAGSNNTQHAVDLSVELEKVGADALLSVVPYYNKTSQRGLVT
HHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEEEHHHHCHHHHHHHHCCCCCCCCCCHHH
HFSTIARAVAIPIILYNIPSRTSFNMTPETIREIAENETVVGIKECNLYQVGEIVKLCGP
HHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCC
EFSIYSGDDSTILPVLAYGGKGVISTMANIIPEETHDIVSYFMRGDIEGARRAQLRALDL
CCEEECCCCCEEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
ISALFVDVNPIPLKTAMNLMGMNVGPCRLPLVDMGNRETELLVRALKDYGLT
HHHHHHCCCCCCHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA