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The map label for this gene is argD [H]

Identifier: 83594607

GI number: 83594607

Start: 3774620

End: 3775810

Strand: Reverse

Name: argD [H]

Synonym: Rru_A3277

Alternate gene names: 83594607

Gene position: 3775810-3774620 (Counterclockwise)

Preceding gene: 83594608

Following gene: 83594606

Centisome position: 86.74

GC content: 68.43

Gene sequence:

>1191_bases
ATGTCGACCGTTCCGGCCGTGATGCCAACCTATTCCCGCGTGGACCTTTCGTTCGACCGCGGCGAGGGTGCGTGGCTCCT
CGCCAACGACGGGCGACGATTTCTTGATTTCGCCTCGGGGATCGCGGTCACCGGCCTTGGCCATGCCCATCCCCATCTGG
TCGAGGCCCTGACCTCCCAGGCGGCCAAGCTGTGGCATTGCTCGAACCTGTTTCGCATCCCCGGTCAGGAACGTCTGGCC
CAGCGGCTGGTCGACGGCTCCTTCGCCGATTCGGTGTTCTTCACCAATTCCGGCGCCGAAGCCATCGAAGCCGCGCTCAA
GCTGGCGCGGCGCCATCAGCATGTGGTGCGGGGCGAGACGGCGCGCTATCGCACGATCGTGACCCGCAACGCCTTTCACG
GGCGGACGCTGGCGACGGTGACCGCCGGCGGTCAGGCCAAGCACGTCAAGGGCTTCGAGCCGCTGGTCGAGGGCTTTGAC
CGCGTGGACTTCGGTGATCTCGACGCCGCCCGCGCCGCCGTCACCGAAGAGACCGCCGCCATCCTGGTCGAGCCGATCCA
GGGCGAGGGCGGCATTTTCCCCGCCCCCGAAGGCTATCTGTCGGGCCTGCGCCGGCTGGCCGACGAGCATGGGTTGCTGC
TGATCCTTGACGAGGTGCAGACCGGCGTCGGCCGTACCGGCAAGCTGTTCGCCCATGAATGGGACGGCATCATTCCCGAC
GTGGTGGCGATCGCCAAGGGCATCGGCGCCGGCTTCCCGATGGGAGCCTGTCTGGCGCGCGAGCCTTACGCCTCGGCCCT
AGTGGCGGGCAGCCATGGCTCGACCTTCGGCGGCAATCCGCTGGCGATGGCGGTCGGCAACGCCGTTCTCGATATCATTC
TGGCCGAGGGCTTCCTCGATGGGGTGTCGGCGCGCGGCGCCGATCTGATCGCCCGTCTTGATGGTCTGGTCCATCGCCAT
CCGACCATTCTGGCCGGCGTGCGCGGACGGGGGTTGATGATCGGGCTGGTCTGCGCCGCGCCCAACGGCGTGGTGCTGAA
CGCCCTGCGCGAGCAGGGGCTGCTGGCCGTTCCGGCGGAGGCCGGGGTGGTGCGGTTGTTGCCGCCGATGATCATCGGCG
AGGCCGAGGTCACCGCCGCCGAAGAGATGATCGACCGCGCCTGCGTCCATCTGGAACGGGAGGCGGCGTGA

Upstream 100 bases:

>100_bases
GGAATGGCGCAATAACACTCGCTTTCCTGCGACGGGCGGCATTCGGTGCCGCCCTCGTTTTTTCAACTCCAAGCATAGCG
AAGTAAGGCGCTGATCAACC

Downstream 100 bases:

>100_bases
TCATGACCGTGATGAAAACCCCCCGGCATTTCCTGGAGTTGTCGGATTTCGACGCGCCGGCCCTGCGCGCCATGCTCGAT
CGCGGGCTGGCCTTCAAGGC

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MSTVPAVMPTYSRVDLSFDRGEGAWLLANDGRRFLDFASGIAVTGLGHAHPHLVEALTSQAAKLWHCSNLFRIPGQERLA
QRLVDGSFADSVFFTNSGAEAIEAALKLARRHQHVVRGETARYRTIVTRNAFHGRTLATVTAGGQAKHVKGFEPLVEGFD
RVDFGDLDAARAAVTEETAAILVEPIQGEGGIFPAPEGYLSGLRRLADEHGLLLILDEVQTGVGRTGKLFAHEWDGIIPD
VVAIAKGIGAGFPMGACLAREPYASALVAGSHGSTFGGNPLAMAVGNAVLDIILAEGFLDGVSARGADLIARLDGLVHRH
PTILAGVRGRGLMIGLVCAAPNGVVLNALREQGLLAVPAEAGVVRLLPPMIIGEAEVTAAEEMIDRACVHLEREAA

Sequences:

>Translated_396_residues
MSTVPAVMPTYSRVDLSFDRGEGAWLLANDGRRFLDFASGIAVTGLGHAHPHLVEALTSQAAKLWHCSNLFRIPGQERLA
QRLVDGSFADSVFFTNSGAEAIEAALKLARRHQHVVRGETARYRTIVTRNAFHGRTLATVTAGGQAKHVKGFEPLVEGFD
RVDFGDLDAARAAVTEETAAILVEPIQGEGGIFPAPEGYLSGLRRLADEHGLLLILDEVQTGVGRTGKLFAHEWDGIIPD
VVAIAKGIGAGFPMGACLAREPYASALVAGSHGSTFGGNPLAMAVGNAVLDIILAEGFLDGVSARGADLIARLDGLVHRH
PTILAGVRGRGLMIGLVCAAPNGVVLNALREQGLLAVPAEAGVVRLLPPMIIGEAEVTAAEEMIDRACVHLEREAA
>Mature_395_residues
STVPAVMPTYSRVDLSFDRGEGAWLLANDGRRFLDFASGIAVTGLGHAHPHLVEALTSQAAKLWHCSNLFRIPGQERLAQ
RLVDGSFADSVFFTNSGAEAIEAALKLARRHQHVVRGETARYRTIVTRNAFHGRTLATVTAGGQAKHVKGFEPLVEGFDR
VDFGDLDAARAAVTEETAAILVEPIQGEGGIFPAPEGYLSGLRRLADEHGLLLILDEVQTGVGRTGKLFAHEWDGIIPDV
VAIAKGIGAGFPMGACLAREPYASALVAGSHGSTFGGNPLAMAVGNAVLDIILAEGFLDGVSARGADLIARLDGLVHRHP
TILAGVRGRGLMIGLVCAAPNGVVLNALREQGLLAVPAEAGVVRLLPPMIIGEAEVTAAEEMIDRACVHLEREAA

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=392, Percent_Identity=33.4183673469388, Blast_Score=215, Evalue=5e-56,
Organism=Homo sapiens, GI284507298, Length=303, Percent_Identity=34.3234323432343, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI13994255, Length=445, Percent_Identity=30.1123595505618, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI37574042, Length=421, Percent_Identity=27.3159144893112, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI24119277, Length=346, Percent_Identity=29.7687861271676, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI226442709, Length=395, Percent_Identity=27.8481012658228, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI226442705, Length=418, Percent_Identity=26.7942583732057, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI188536080, Length=414, Percent_Identity=25.8454106280193, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI38679950, Length=414, Percent_Identity=25.8454106280193, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI38679946, Length=414, Percent_Identity=25.8454106280193, Blast_Score=99, Evalue=9e-21,
Organism=Escherichia coli, GI1788044, Length=389, Percent_Identity=44.4730077120823, Blast_Score=319, Evalue=2e-88,
Organism=Escherichia coli, GI1789759, Length=375, Percent_Identity=41.8666666666667, Blast_Score=287, Evalue=1e-78,
Organism=Escherichia coli, GI145693181, Length=364, Percent_Identity=36.8131868131868, Blast_Score=214, Evalue=9e-57,
Organism=Escherichia coli, GI1789016, Length=403, Percent_Identity=33.0024813895782, Blast_Score=187, Evalue=7e-49,
Organism=Escherichia coli, GI1787560, Length=407, Percent_Identity=33.9066339066339, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1786991, Length=416, Percent_Identity=31.7307692307692, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1786349, Length=313, Percent_Identity=31.3099041533546, Blast_Score=115, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI25144271, Length=393, Percent_Identity=33.3333333333333, Blast_Score=221, Evalue=6e-58,
Organism=Caenorhabditis elegans, GI32564660, Length=454, Percent_Identity=31.7180616740088, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI25144274, Length=274, Percent_Identity=34.6715328467153, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71992977, Length=434, Percent_Identity=27.4193548387097, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71981843, Length=167, Percent_Identity=29.940119760479, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17541228, Length=382, Percent_Identity=25.6544502617801, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6324432, Length=393, Percent_Identity=37.1501272264631, Blast_Score=254, Evalue=1e-68,
Organism=Saccharomyces cerevisiae, GI6323470, Length=403, Percent_Identity=32.7543424317618, Blast_Score=200, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6324386, Length=409, Percent_Identity=25.9168704156479, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6321456, Length=388, Percent_Identity=26.5463917525773, Blast_Score=97, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21357415, Length=395, Percent_Identity=31.3924050632911, Blast_Score=212, Evalue=4e-55,
Organism=Drosophila melanogaster, GI28574759, Length=419, Percent_Identity=32.6968973747017, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI161085790, Length=422, Percent_Identity=32.2274881516588, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI21356575, Length=411, Percent_Identity=29.683698296837, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI281366494, Length=412, Percent_Identity=25.7281553398058, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24667139, Length=412, Percent_Identity=25.7281553398058, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24667143, Length=412, Percent_Identity=25.7281553398058, Blast_Score=92, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 41722; Mature: 41591

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVPAVMPTYSRVDLSFDRGEGAWLLANDGRRFLDFASGIAVTGLGHAHPHLVEALTSQ
CCCCCCCCCCCCEEEEEEECCCCEEEEECCCCHHHHHHCCCEEECCCCCCHHHHHHHHHH
AAKLWHCSNLFRIPGQERLAQRLVDGSFADSVFFTNSGAEAIEAALKLARRHQHVVRGET
HHHHHHHCCHHCCCCHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCC
ARYRTIVTRNAFHGRTLATVTAGGQAKHVKGFEPLVEGFDRVDFGDLDAARAAVTEETAA
HHEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHCCEE
ILVEPIQGEGGIFPAPEGYLSGLRRLADEHGLLLILDEVQTGVGRTGKLFAHEWDGIIPD
EEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECHHCCCCCCCCEEEECCCCCHHH
VVAIAKGIGAGFPMGACLAREPYASALVAGSHGSTFGGNPLAMAVGNAVLDIILAEGFLD
HHHHHHHCCCCCCCHHHHHCCCHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GVSARGADLIARLDGLVHRHPTILAGVRGRGLMIGLVCAAPNGVVLNALREQGLLAVPAE
CCCCCCHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEEECCCCHHHHHHHHCCCEEECCC
AGVVRLLPPMIIGEAEVTAAEEMIDRACVHLEREAA
CCCHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STVPAVMPTYSRVDLSFDRGEGAWLLANDGRRFLDFASGIAVTGLGHAHPHLVEALTSQ
CCCCCCCCCCCEEEEEEECCCCEEEEECCCCHHHHHHCCCEEECCCCCCHHHHHHHHHH
AAKLWHCSNLFRIPGQERLAQRLVDGSFADSVFFTNSGAEAIEAALKLARRHQHVVRGET
HHHHHHHCCHHCCCCHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCC
ARYRTIVTRNAFHGRTLATVTAGGQAKHVKGFEPLVEGFDRVDFGDLDAARAAVTEETAA
HHEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHCCEE
ILVEPIQGEGGIFPAPEGYLSGLRRLADEHGLLLILDEVQTGVGRTGKLFAHEWDGIIPD
EEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECHHCCCCCCCCEEEECCCCCHHH
VVAIAKGIGAGFPMGACLAREPYASALVAGSHGSTFGGNPLAMAVGNAVLDIILAEGFLD
HHHHHHHCCCCCCCHHHHHCCCHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GVSARGADLIARLDGLVHRHPTILAGVRGRGLMIGLVCAAPNGVVLNALREQGLLAVPAE
CCCCCCHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEEECCCCHHHHHHHHCCCEEECCC
AGVVRLLPPMIIGEAEVTAAEEMIDRACVHLEREAA
CCCHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]