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The map label for this gene is lysA [H]

Identifier: 83594465

GI number: 83594465

Start: 3614947

End: 3616161

Strand: Direct

Name: lysA [H]

Synonym: Rru_A3135

Alternate gene names: 83594465

Gene position: 3614947-3616161 (Clockwise)

Preceding gene: 83594464

Following gene: 83594467

Centisome position: 83.05

GC content: 71.19

Gene sequence:

>1215_bases
ATGACCGCCTCCCCGCCCCCCGGCTTCGGCGTGAGCGGAAGCGACTTGACAATCGGCGGCCAAAGGGTGTCGCACCTGGC
GCGGATCGCCGGGGGCACGCCGTTTTACGCCTATGACCGGGGCGCGGTGAGCGCGCGCATCGCCGCCCTGCGCGCGGCGC
TGCCGGCCGGGATGGCGATCCGCTATTCCCTCAAGGCCAATCCGATGGCGGCCCTGCTCGCCCATATGGCGCCGCTAGTC
GATGGCTTCGATGCCGCCTCGGCCGGCGAACTGCGCGCCGGTTTGGCCGTGGGCATGGCCCCGGCGGCGCTGTCGATCGC
CGGCCCGGGAAAAAGCCCGGCCGATATTCTTAGCGCCGTGGCGGCGGGGGCGCTGGTGGTCGTGGAAAGCCTGGCCGAGG
TCGGACGGGTCGCCCAGGCCGGAAACGCCAGCGGCCTGCGCCCGCGCGTCCTGGTCCGCGTCAACCCCGAGGCCGAGATC
CAGGGCGCGGGCTTGCGCATGGGTGGCGGCGCCCGTCCCTTTGGCATCGACGCCGATCAGGTGCCCGGGGTGCTGGCCGC
CATCGCCGCCCATGATCTCGACTATCAGGGCCTGCATTGTTTCTGGGGCTCGCAGGCGCTGGACGCCGAACGCATCGCCC
GCGCCTTCGCCGTGGTCGGCCAGACCCTGCTCGACCTCGCCGGCCCGCGGCCGCCACGCCAGATCGTCATCGGCGGCGGC
TTTGGCATCCCTTACACGCCGACCAGCGCGCCGCTTGATCTGGCGCGCGCCGGGGCCGCCGTCGCCGAGACCGCCGGCCT
GCTTGGCGACCACCTGCCGGGGGTGAGCCTGGGCCTCGAGTTGGGCCGGTTCCTGGTCGGCGAGGCCGGCGTATATGTTT
GCGCCATCCGTGAAAGCAAGCGCTCGCGCGGGAACCTGTTTTTGGTGACCGATGGCGGGCTGCACCACAATCAGGCGGCC
ACCGGTAATTTCGGTCAGGTGGTGCGACGGCCCTATCCCCTGGTCATCGCCACCAGGATGGGCGAGCCCGTAAGCGAGCG
GGCGACGATCACCGGCTGCCTGTGCACCCCGCTCGATGTCTTCGCCGAGGCTTTGGCGATCCCGGCGGCGGCCGAGGGCG
ATCTGGTGGCGATCTTCCAATCTGGCGCCTATGGGGCCAGCGCTAGCCCGAGCGCCTTTCTCGGGCATCCCCCGGCGGTT
GAACTGCTGGTGTAA

Upstream 100 bases:

>100_bases
CCCTGCTGACCCAGGTGGACAGCCTGCCGCGCACGGCCAGCGGCAAGGCCGATCGGGCGGCGGCGCGGGCGAGGATGCTC
AAGGACCAGGAGTCTCCGCC

Downstream 100 bases:

>100_bases
GCCAACGGCCGCCCCCGGCCGGGTTATTCCCCCGGCCTCGATGGGTCGAGACCGTTCATTTCACTGCCCTTTTTCAAGCT
ATCCCCATAATTCGGGAAAA

Product: Orn/DAP/Arg decarboxylase 2

Products: NA

Alternate protein names: DAP decarboxylase [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTASPPPGFGVSGSDLTIGGQRVSHLARIAGGTPFYAYDRGAVSARIAALRAALPAGMAIRYSLKANPMAALLAHMAPLV
DGFDAASAGELRAGLAVGMAPAALSIAGPGKSPADILSAVAAGALVVVESLAEVGRVAQAGNASGLRPRVLVRVNPEAEI
QGAGLRMGGGARPFGIDADQVPGVLAAIAAHDLDYQGLHCFWGSQALDAERIARAFAVVGQTLLDLAGPRPPRQIVIGGG
FGIPYTPTSAPLDLARAGAAVAETAGLLGDHLPGVSLGLELGRFLVGEAGVYVCAIRESKRSRGNLFLVTDGGLHHNQAA
TGNFGQVVRRPYPLVIATRMGEPVSERATITGCLCTPLDVFAEALAIPAAAEGDLVAIFQSGAYGASASPSAFLGHPPAV
ELLV

Sequences:

>Translated_404_residues
MTASPPPGFGVSGSDLTIGGQRVSHLARIAGGTPFYAYDRGAVSARIAALRAALPAGMAIRYSLKANPMAALLAHMAPLV
DGFDAASAGELRAGLAVGMAPAALSIAGPGKSPADILSAVAAGALVVVESLAEVGRVAQAGNASGLRPRVLVRVNPEAEI
QGAGLRMGGGARPFGIDADQVPGVLAAIAAHDLDYQGLHCFWGSQALDAERIARAFAVVGQTLLDLAGPRPPRQIVIGGG
FGIPYTPTSAPLDLARAGAAVAETAGLLGDHLPGVSLGLELGRFLVGEAGVYVCAIRESKRSRGNLFLVTDGGLHHNQAA
TGNFGQVVRRPYPLVIATRMGEPVSERATITGCLCTPLDVFAEALAIPAAAEGDLVAIFQSGAYGASASPSAFLGHPPAV
ELLV
>Mature_403_residues
TASPPPGFGVSGSDLTIGGQRVSHLARIAGGTPFYAYDRGAVSARIAALRAALPAGMAIRYSLKANPMAALLAHMAPLVD
GFDAASAGELRAGLAVGMAPAALSIAGPGKSPADILSAVAAGALVVVESLAEVGRVAQAGNASGLRPRVLVRVNPEAEIQ
GAGLRMGGGARPFGIDADQVPGVLAAIAAHDLDYQGLHCFWGSQALDAERIARAFAVVGQTLLDLAGPRPPRQIVIGGGF
GIPYTPTSAPLDLARAGAAVAETAGLLGDHLPGVSLGLELGRFLVGEAGVYVCAIRESKRSRGNLFLVTDGGLHHNQAAT
GNFGQVVRRPYPLVIATRMGEPVSERATITGCLCTPLDVFAEALAIPAAAEGDLVAIFQSGAYGASASPSAFLGHPPAVE
LLV

Specific function: Lysine biosynthesis; last step. [C]

COG id: COG0019

COG function: function code E; Diaminopimelate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family [H]

Homologues:

Organism=Escherichia coli, GI1789203, Length=384, Percent_Identity=26.3020833333333, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002986
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.20 [H]

Molecular weight: Translated: 40786; Mature: 40655

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASPPPGFGVSGSDLTIGGQRVSHLARIAGGTPFYAYDRGAVSARIAALRAALPAGMAI
CCCCCCCCCCCCCCCEEECHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCEEE
RYSLKANPMAALLAHMAPLVDGFDAASAGELRAGLAVGMAPAALSIAGPGKSPADILSAV
EEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCHHHHHHHH
AAGALVVVESLAEVGRVAQAGNASGLRPRVLVRVNPEAEIQGAGLRMGGGARPFGIDADQ
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEECCCEEECCCCCCCCCCHHH
VPGVLAAIAAHDLDYQGLHCFWGSQALDAERIARAFAVVGQTLLDLAGPRPPRQIVIGGG
HHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECC
FGIPYTPTSAPLDLARAGAAVAETAGLLGDHLPGVSLGLELGRFLVGEAGVYVCAIRESK
CCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEEECCC
RSRGNLFLVTDGGLHHNQAATGNFGQVVRRPYPLVIATRMGEPVSERATITGCLCTPLDV
CCCCCEEEEECCCCCCCCCCCCCHHHHHHCCCCEEEEECCCCCCHHCCEEEEEECCCHHH
FAEALAIPAAAEGDLVAIFQSGAYGASASPSAFLGHPPAVELLV
HHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEC
>Mature Secondary Structure 
TASPPPGFGVSGSDLTIGGQRVSHLARIAGGTPFYAYDRGAVSARIAALRAALPAGMAI
CCCCCCCCCCCCCCEEECHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCEEE
RYSLKANPMAALLAHMAPLVDGFDAASAGELRAGLAVGMAPAALSIAGPGKSPADILSAV
EEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCHHHHHHHH
AAGALVVVESLAEVGRVAQAGNASGLRPRVLVRVNPEAEIQGAGLRMGGGARPFGIDADQ
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEECCCEEECCCCCCCCCCHHH
VPGVLAAIAAHDLDYQGLHCFWGSQALDAERIARAFAVVGQTLLDLAGPRPPRQIVIGGG
HHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECC
FGIPYTPTSAPLDLARAGAAVAETAGLLGDHLPGVSLGLELGRFLVGEAGVYVCAIRESK
CCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEEECCC
RSRGNLFLVTDGGLHHNQAATGNFGQVVRRPYPLVIATRMGEPVSERATITGCLCTPLDV
CCCCCEEEEECCCCCCCCCCCCCHHHHHHCCCCEEEEECCCCCCHHCCEEEEEECCCHHH
FAEALAIPAAAEGDLVAIFQSGAYGASASPSAFLGHPPAVELLV
HHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]