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The map label for this gene is glmS [H]

Identifier: 83594359

GI number: 83594359

Start: 3486947

End: 3488770

Strand: Reverse

Name: glmS [H]

Synonym: Rru_A3029

Alternate gene names: 83594359

Gene position: 3488770-3486947 (Counterclockwise)

Preceding gene: 83594360

Following gene: 83594351

Centisome position: 80.15

GC content: 65.73

Gene sequence:

>1824_bases
ATGTGCGGCATCATCGGCATTATCGGCGTCAAGGACGTGGTTCCCTCGTTGATGGAAGGCCTGAGGCGGCTGGAATACCG
GGGCTATGATTCCACCGGCATCGCCACCCTGGTCGATGGCGTCATCGATCGCCGCCGGGCGCAGGGCAAGCTGGGCAATC
TGGAAAAGCGCCTAGTCGAGGCGCCGCTGGCCGGCATCATCGGCATCGGCCATACGCGCTGGGCCACCCATGGCGTGCCC
AATGAGGTCAACGCCCATCCCCACGCCAGCGCCAAGGTGGCGGTGGTTCATAACGGCATCATCGAGAACTTCGTTGCCCT
GCGCGATCGCCTGCTGGCCAAGGGCCATGTCTTCGCCACCGCCACCGATACCGAGGCGGTCGTCCATCTGATCACCGAGT
ACCTCGATGAGGGTCTGAGCCCGGAAGAGGCGGTGGGCAAGGCGATCGGCGAGCTGGAAGGCGCCTTCGCCCTGGTCATC
CTGATCGCCGGCGAGGAAAACCTGCTGTTCGCCGCGCGCAAGGGCAGCCCGCTGGCCGTGGGCTATGGCGACGGCGAGAT
GTTCCTTGGCTCGGACGCCCTGACCCTGGCGCCGCTCACCCGGCGCATCGCCTATCTGGAAGATGGCGATTGGGTGCGGG
TGACCCGCGAGGGCGCGGTGTTCCGCGATGTCAGCGGCGCCATCGTCGAGCGCAAGATCCATCTGTCGTCGGTTTCGGGG
GCGATGATCGGCAAGGGCGGCCATCGCCACTACATGCTCAAGGAAATCTACGAGCAGCCGCAGGTGATCGGCGACACCCT
GAACGCCATGTTCAATCCGGTCGAACGCACGATCACCCTGCCGCCGCTGCCCTTCGCCCTCGATGATGTGGAGCGGGTGA
CGCTGATCGCTTGCGGCACCTCGTCCTATGCGGCGATGGTCGCGCGCTATTGGATCGAATCCATCGCCCGCGTGCCCGTC
GATCTCGATGTCGGCAGTGAATTCCGCTACCGCGATCCGCCGCTGCAAGCCGGCGGGCTGGCGCTGTTCATCAGCCAGTC
GGGCGAGACCGCCGATACCTTGGCCGCGCTCCGCCACTGCAAGGCCAAGGGCCTGCGCTGCCTGTCGATCGTCAATGTGG
CCGAAAGCACCATGGCCCGCGAATCCGACGCCGTGCTGACCACCCTGGCCGGTCCCGAGATCGGCGTCGCCTCGACCAAG
GCCTTCACCACCCAATTGGTGGTTCTCGCCTGCCTGACCATTGCCCTGGCCCGGGCCAAGGGTCAACTTGATGCCGATGG
CGAGGCGCGGCTCTCCAAGGGGTTGACCGAGGTGCCGGCGCGCGCCGCCGAGATCTTGAAATACGACGAGGACCTGCGCG
CCATCGCCCAGACCGTGGCCGAGGCCCGCGACGTGCTCTATCTGGGGCGCGGCACCGCCTTCCCCATCGCCCTGGAAGGC
GCGCTGAAGCTCAAGGAAATCAGCTATATCCACGCCGAGGGCTATGCGGCGGGCGAAATGAAGCACGGCCCCATCGCCCT
GATCGACGAAACCGTGCCGGTGATCGTCATCGCCCCATCGGATGGCTTGTTCGACAAGACCGCCTCGAACGTCCAGGAGG
TCGTCGCCCGCGGCGGCAAGGTGATTTTCCTGTCCGATAGCGAGGGCAATCGCCGTCTGGGCGTCACCCCGGCCTTTTCA
GTGGTGCTGCCCGCCGTCGATCCCTTCGTCGCCCCGATCCTCTATGCGATCCCGGTCCAGCTTCTGGCCTATCACGTCGC
CGTCATCAAAGGCACCGACGTGGACCAGCCGCGCAATCTGGCCAAGAGCGTGACGGTCGAATAG

Upstream 100 bases:

>100_bases
CGGCCAAGTTCCGCGCGCATATGCGCCGGCTGACCGGCAAAAATTAGCTCGCGGGGGTTCCCCGGCGGTATTTCGTGTTT
TCTAAGGAGTGGCTCCACCC

Downstream 100 bases:

>100_bases
GGCGCGTCGCCGGGGCGGGGGTGGTGGCGGGGAGGGGTCAGTTGGTCCCCTCGACCCAGGCGATGTAGGCGCCGACATTC
AGCGCCTCTTGCATCATCAC

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 607; Mature: 607

Protein sequence:

>607_residues
MCGIIGIIGVKDVVPSLMEGLRRLEYRGYDSTGIATLVDGVIDRRRAQGKLGNLEKRLVEAPLAGIIGIGHTRWATHGVP
NEVNAHPHASAKVAVVHNGIIENFVALRDRLLAKGHVFATATDTEAVVHLITEYLDEGLSPEEAVGKAIGELEGAFALVI
LIAGEENLLFAARKGSPLAVGYGDGEMFLGSDALTLAPLTRRIAYLEDGDWVRVTREGAVFRDVSGAIVERKIHLSSVSG
AMIGKGGHRHYMLKEIYEQPQVIGDTLNAMFNPVERTITLPPLPFALDDVERVTLIACGTSSYAAMVARYWIESIARVPV
DLDVGSEFRYRDPPLQAGGLALFISQSGETADTLAALRHCKAKGLRCLSIVNVAESTMARESDAVLTTLAGPEIGVASTK
AFTTQLVVLACLTIALARAKGQLDADGEARLSKGLTEVPARAAEILKYDEDLRAIAQTVAEARDVLYLGRGTAFPIALEG
ALKLKEISYIHAEGYAAGEMKHGPIALIDETVPVIVIAPSDGLFDKTASNVQEVVARGGKVIFLSDSEGNRRLGVTPAFS
VVLPAVDPFVAPILYAIPVQLLAYHVAVIKGTDVDQPRNLAKSVTVE

Sequences:

>Translated_607_residues
MCGIIGIIGVKDVVPSLMEGLRRLEYRGYDSTGIATLVDGVIDRRRAQGKLGNLEKRLVEAPLAGIIGIGHTRWATHGVP
NEVNAHPHASAKVAVVHNGIIENFVALRDRLLAKGHVFATATDTEAVVHLITEYLDEGLSPEEAVGKAIGELEGAFALVI
LIAGEENLLFAARKGSPLAVGYGDGEMFLGSDALTLAPLTRRIAYLEDGDWVRVTREGAVFRDVSGAIVERKIHLSSVSG
AMIGKGGHRHYMLKEIYEQPQVIGDTLNAMFNPVERTITLPPLPFALDDVERVTLIACGTSSYAAMVARYWIESIARVPV
DLDVGSEFRYRDPPLQAGGLALFISQSGETADTLAALRHCKAKGLRCLSIVNVAESTMARESDAVLTTLAGPEIGVASTK
AFTTQLVVLACLTIALARAKGQLDADGEARLSKGLTEVPARAAEILKYDEDLRAIAQTVAEARDVLYLGRGTAFPIALEG
ALKLKEISYIHAEGYAAGEMKHGPIALIDETVPVIVIAPSDGLFDKTASNVQEVVARGGKVIFLSDSEGNRRLGVTPAFS
VVLPAVDPFVAPILYAIPVQLLAYHVAVIKGTDVDQPRNLAKSVTVE
>Mature_607_residues
MCGIIGIIGVKDVVPSLMEGLRRLEYRGYDSTGIATLVDGVIDRRRAQGKLGNLEKRLVEAPLAGIIGIGHTRWATHGVP
NEVNAHPHASAKVAVVHNGIIENFVALRDRLLAKGHVFATATDTEAVVHLITEYLDEGLSPEEAVGKAIGELEGAFALVI
LIAGEENLLFAARKGSPLAVGYGDGEMFLGSDALTLAPLTRRIAYLEDGDWVRVTREGAVFRDVSGAIVERKIHLSSVSG
AMIGKGGHRHYMLKEIYEQPQVIGDTLNAMFNPVERTITLPPLPFALDDVERVTLIACGTSSYAAMVARYWIESIARVPV
DLDVGSEFRYRDPPLQAGGLALFISQSGETADTLAALRHCKAKGLRCLSIVNVAESTMARESDAVLTTLAGPEIGVASTK
AFTTQLVVLACLTIALARAKGQLDADGEARLSKGLTEVPARAAEILKYDEDLRAIAQTVAEARDVLYLGRGTAFPIALEG
ALKLKEISYIHAEGYAAGEMKHGPIALIDETVPVIVIAPSDGLFDKTASNVQEVVARGGKVIFLSDSEGNRRLGVTPAFS
VVLPAVDPFVAPILYAIPVQLLAYHVAVIKGTDVDQPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=696, Percent_Identity=36.4942528735632, Blast_Score=391, Evalue=1e-109,
Organism=Homo sapiens, GI205277386, Length=686, Percent_Identity=34.9854227405248, Blast_Score=381, Evalue=1e-106,
Organism=Escherichia coli, GI1790167, Length=611, Percent_Identity=51.063829787234, Blast_Score=582, Evalue=1e-167,
Organism=Escherichia coli, GI1788651, Length=242, Percent_Identity=28.9256198347107, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI87082251, Length=314, Percent_Identity=21.0191082802548, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17532899, Length=719, Percent_Identity=33.518776077886, Blast_Score=364, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17532897, Length=433, Percent_Identity=37.6443418013857, Blast_Score=281, Evalue=7e-76,
Organism=Caenorhabditis elegans, GI17539970, Length=430, Percent_Identity=36.7441860465116, Blast_Score=280, Evalue=2e-75,
Organism=Saccharomyces cerevisiae, GI6322745, Length=489, Percent_Identity=35.9918200408998, Blast_Score=275, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6323731, Length=432, Percent_Identity=29.6296296296296, Blast_Score=189, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6323730, Length=207, Percent_Identity=36.7149758454106, Blast_Score=116, Evalue=8e-27,
Organism=Drosophila melanogaster, GI21357745, Length=689, Percent_Identity=35.7039187227866, Blast_Score=395, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 64792; Mature: 64792

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIIGIIGVKDVVPSLMEGLRRLEYRGYDSTGIATLVDGVIDRRRAQGKLGNLEKRLVE
CCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
APLAGIIGIGHTRWATHGVPNEVNAHPHASAKVAVVHNGIIENFVALRDRLLAKGHVFAT
CCHHHHEECCCCCHHCCCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHCCCEEEE
ATDTEAVVHLITEYLDEGLSPEEAVGKAIGELEGAFALVILIAGEENLLFAARKGSPLAV
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEECCCCEEEE
GYGDGEMFLGSDALTLAPLTRRIAYLEDGDWVRVTREGAVFRDVSGAIVERKIHLSSVSG
EECCCCEEECCCCHHHHHHHHHHEEEECCCEEEEEECCCEEECCCCHHHHHEEEHHHCCC
AMIGKGGHRHYMLKEIYEQPQVIGDTLNAMFNPVERTITLPPLPFALDDVERVTLIACGT
HHCCCCCCCHHHHHHHHHCHHHHHHHHHHHHCCHHHEEECCCCCCCCCCCCEEEEEEECC
SSYAAMVARYWIESIARVPVDLDVGSEFRYRDPPLQAGGLALFISQSGETADTLAALRHC
CHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHH
KAKGLRCLSIVNVAESTMARESDAVLTTLAGPEIGVASTKAFTTQLVVLACLTIALARAK
HHCCCEEHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
GQLDADGEARLSKGLTEVPARAAEILKYDEDLRAIAQTVAEARDVLYLGRGTAFPIALEG
CCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEECC
ALKLKEISYIHAEGYAAGEMKHGPIALIDETVPVIVIAPSDGLFDKTASNVQEVVARGGK
CEEEEHEEEEEECCCCCCCCCCCCEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHCCCE
VIFLSDSEGNRRLGVTPAFSVVLPAVDPFVAPILYAIPVQLLAYHVAVIKGTDVDQPRNL
EEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHH
AKSVTVE
HHHCCCC
>Mature Secondary Structure
MCGIIGIIGVKDVVPSLMEGLRRLEYRGYDSTGIATLVDGVIDRRRAQGKLGNLEKRLVE
CCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
APLAGIIGIGHTRWATHGVPNEVNAHPHASAKVAVVHNGIIENFVALRDRLLAKGHVFAT
CCHHHHEECCCCCHHCCCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHCCCEEEE
ATDTEAVVHLITEYLDEGLSPEEAVGKAIGELEGAFALVILIAGEENLLFAARKGSPLAV
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEECCCCEEEE
GYGDGEMFLGSDALTLAPLTRRIAYLEDGDWVRVTREGAVFRDVSGAIVERKIHLSSVSG
EECCCCEEECCCCHHHHHHHHHHEEEECCCEEEEEECCCEEECCCCHHHHHEEEHHHCCC
AMIGKGGHRHYMLKEIYEQPQVIGDTLNAMFNPVERTITLPPLPFALDDVERVTLIACGT
HHCCCCCCCHHHHHHHHHCHHHHHHHHHHHHCCHHHEEECCCCCCCCCCCCEEEEEEECC
SSYAAMVARYWIESIARVPVDLDVGSEFRYRDPPLQAGGLALFISQSGETADTLAALRHC
CHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHH
KAKGLRCLSIVNVAESTMARESDAVLTTLAGPEIGVASTKAFTTQLVVLACLTIALARAK
HHCCCEEHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
GQLDADGEARLSKGLTEVPARAAEILKYDEDLRAIAQTVAEARDVLYLGRGTAFPIALEG
CCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEECC
ALKLKEISYIHAEGYAAGEMKHGPIALIDETVPVIVIAPSDGLFDKTASNVQEVVARGGK
CEEEEHEEEEEECCCCCCCCCCCCEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHCCCE
VIFLSDSEGNRRLGVTPAFSVVLPAVDPFVAPILYAIPVQLLAYHVAVIKGTDVDQPRNL
EEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHH
AKSVTVE
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA