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The map label for this gene is cobL [H]

Identifier: 83594322

GI number: 83594322

Start: 3444154

End: 3445380

Strand: Direct

Name: cobL [H]

Synonym: Rru_A2992

Alternate gene names: 83594322

Gene position: 3444154-3445380 (Clockwise)

Preceding gene: 83594318

Following gene: 83594332

Centisome position: 79.12

GC content: 71.72

Gene sequence:

>1227_bases
ATGACAGCGTGGCTGACGGTGGTGGGCATCGGCGAGGACGGTTTGGCCGGCCTGGGCGAGGGAGCGCGCGACGCCATCGC
CAAGGCCTCGCTGCTGCTGGGCGGCCAGCGCCACCTTGATCTGGTTCCGGTGGTCGCAGGGCAGGAGCGCCAAGCTTGGC
CCAGCCCGTTTTCCCTGGCCTATGATCTGGTGCTGGCCCGCCGAGGAACGCCGGTCTGCGTGCTGGCTAGCGGCGATCCC
ATGCATTACGGCATCGGCGCCTCGCTGGCCGCGAGGCTCGAGCCGGGCGAAATGCGGGTGCTGCCCGCGCCCTCGTCGTT
CTCGCTGGCTGCCGCCCGTCTGTGCTGGCCGCTGCAGGACTGCCAACTGCTGACCGTCCATGGCCGCCCGCTCGAGAGCG
TCAGGGTGGCTCTTTATCCCGAGGCCCGGCTGCTGATCTTGTCGGAAGACGGCCAGACCCCGGCCGCCCTGGCCGCCTTG
CTGGTGGAACGCGGCTTTGGCGAGAGCCCGTTCATCGTGCTCGAACACCTGGGCGGCCCGACTGAGCGCATCCGCCACGC
CACGGCGCGCGGCTGGCTGGCGGCCGAGTCCGCGCCTTGCGCCGATCTCAATCTGGTGGCCGTCGACTGCCGGGCCGAGG
CGGGCGCCCAGTCCTGGCCCCGGCTGGCCGGCCTGCCCGACAGCGCCTATCGCCACGACGGCCAATTGACCAAACGCGCC
GTCCGCGCCGTGACGCTGGCCCACCTCGCCCCCTTGCCCGGCCAGGTGCTGTGGGACGTGGGGGCGGGCTGCGGCTCGAT
CGGCATCGAATGGATGCGCAGCGCGCCCAGCTGCCGGGCCTTCGCCATCGAAGCCGATGCCGAACGCGCCGATGTCATCG
CCCATAATCGCGCCGCCCTGGGCGTTCCCGGCCTGGAACTGGTGGAAGGCCGCGCCCCGGCGGTGCTTGAAGGCCTGCCC
GATCCCGACGCCATCTTCATCGGCGGCGGCCTGACCGCCAATGGCGTGTTCGAACGCTGCTGGATCGCCCTGAAACCGGG
CGGCCGGCTGGTCGCCAACGCCGTCACCCTCGAAAGCGAGGCCCGCCTCGCCCATTGGCACGGCGTGCTAGGCGGCGAGC
TGACCCGCCTCTCGGTCGCCCACGCCGACCCCGTCGGCCGCTTCCACGGCTGGCGCTCGGCGATGCCGGTGACGCTCTAT
GAGGTGGTCAAGCCCAAGCAGGGGTGA

Upstream 100 bases:

>100_bases
GCAGGCGGCGAAAGCCCGCGTTCCGCCGGGGGTTGCGGCGGGGAGCGGCGTCGCGTATCACGCCCGAAGGCAGGGATTTT
GGCCCGGAAAGGAAGCGACC

Downstream 100 bases:

>100_bases
GGGGGGTGACAGGTATTACCTAGAACCGGCTCTCATAGGCTTGACACCGCCTCGTCGTCCTAATCCGAATCCGACTCGGT
AAAGATCGGGCATATTAAGA

Product: precorrin-6Y C5,15-methyltransferase (decarboxylating)

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MTAWLTVVGIGEDGLAGLGEGARDAIAKASLLLGGQRHLDLVPVVAGQERQAWPSPFSLAYDLVLARRGTPVCVLASGDP
MHYGIGASLAARLEPGEMRVLPAPSSFSLAAARLCWPLQDCQLLTVHGRPLESVRVALYPEARLLILSEDGQTPAALAAL
LVERGFGESPFIVLEHLGGPTERIRHATARGWLAAESAPCADLNLVAVDCRAEAGAQSWPRLAGLPDSAYRHDGQLTKRA
VRAVTLAHLAPLPGQVLWDVGAGCGSIGIEWMRSAPSCRAFAIEADAERADVIAHNRAALGVPGLELVEGRAPAVLEGLP
DPDAIFIGGGLTANGVFERCWIALKPGGRLVANAVTLESEARLAHWHGVLGGELTRLSVAHADPVGRFHGWRSAMPVTLY
EVVKPKQG

Sequences:

>Translated_408_residues
MTAWLTVVGIGEDGLAGLGEGARDAIAKASLLLGGQRHLDLVPVVAGQERQAWPSPFSLAYDLVLARRGTPVCVLASGDP
MHYGIGASLAARLEPGEMRVLPAPSSFSLAAARLCWPLQDCQLLTVHGRPLESVRVALYPEARLLILSEDGQTPAALAAL
LVERGFGESPFIVLEHLGGPTERIRHATARGWLAAESAPCADLNLVAVDCRAEAGAQSWPRLAGLPDSAYRHDGQLTKRA
VRAVTLAHLAPLPGQVLWDVGAGCGSIGIEWMRSAPSCRAFAIEADAERADVIAHNRAALGVPGLELVEGRAPAVLEGLP
DPDAIFIGGGLTANGVFERCWIALKPGGRLVANAVTLESEARLAHWHGVLGGELTRLSVAHADPVGRFHGWRSAMPVTLY
EVVKPKQG
>Mature_407_residues
TAWLTVVGIGEDGLAGLGEGARDAIAKASLLLGGQRHLDLVPVVAGQERQAWPSPFSLAYDLVLARRGTPVCVLASGDPM
HYGIGASLAARLEPGEMRVLPAPSSFSLAAARLCWPLQDCQLLTVHGRPLESVRVALYPEARLLILSEDGQTPAALAALL
VERGFGESPFIVLEHLGGPTERIRHATARGWLAAESAPCADLNLVAVDCRAEAGAQSWPRLAGLPDSAYRHDGQLTKRAV
RAVTLAHLAPLPGQVLWDVGAGCGSIGIEWMRSAPSCRAFAIEADAERADVIAHNRAALGVPGLELVEGRAPAVLEGLPD
PDAIFIGGGLTANGVFERCWIALKPGGRLVANAVTLESEARLAHWHGVLGGELTRLSVAHADPVGRFHGWRSAMPVTLYE
VVKPKQG

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 43008; Mature: 42877

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAWLTVVGIGEDGLAGLGEGARDAIAKASLLLGGQRHLDLVPVVAGQERQAWPSPFSLA
CCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHH
YDLVLARRGTPVCVLASGDPMHYGIGASLAARLEPGEMRVLPAPSSFSLAAARLCWPLQD
HHHHHHCCCCCEEEEECCCCEEECCCCCEEEECCCCCEEEEECCCCCHHHHHHHHCCCCC
CQLLTVHGRPLESVRVALYPEARLLILSEDGQTPAALAALLVERGFGESPFIVLEHLGGP
CEEEEECCCCCCCEEEEEECCEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEECCCH
TERIRHATARGWLAAESAPCADLNLVAVDCRAEAGAQSWPRLAGLPDSAYRHDGQLTKRA
HHHHHHHHHCCEEEECCCCCCCCEEEEEECCCCCCCCCCCHHCCCCCHHHHCCCHHHHHH
VRAVTLAHLAPLPGQVLWDVGAGCGSIGIEWMRSAPSCRAFAIEADAERADVIAHNRAAL
HHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCCCCEEEEEECCCCCHHHEECCCCCC
GVPGLELVEGRAPAVLEGLPDPDAIFIGGGLTANGVFERCWIALKPGGRLVANAVTLESE
CCCCHHHHCCCCCHHHCCCCCCCEEEECCCCCCCCCEEEEEEEECCCCEEEEEEEEECCC
ARLAHWHGVLGGELTRLSVAHADPVGRFHGWRSAMPVTLYEVVKPKQG
CHHHHHHCCCCCCEEEEEEECCCCCHHHCCHHCCCCEEEEHHHCCCCC
>Mature Secondary Structure 
TAWLTVVGIGEDGLAGLGEGARDAIAKASLLLGGQRHLDLVPVVAGQERQAWPSPFSLA
CEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHH
YDLVLARRGTPVCVLASGDPMHYGIGASLAARLEPGEMRVLPAPSSFSLAAARLCWPLQD
HHHHHHCCCCCEEEEECCCCEEECCCCCEEEECCCCCEEEEECCCCCHHHHHHHHCCCCC
CQLLTVHGRPLESVRVALYPEARLLILSEDGQTPAALAALLVERGFGESPFIVLEHLGGP
CEEEEECCCCCCCEEEEEECCEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEECCCH
TERIRHATARGWLAAESAPCADLNLVAVDCRAEAGAQSWPRLAGLPDSAYRHDGQLTKRA
HHHHHHHHHCCEEEECCCCCCCCEEEEEECCCCCCCCCCCHHCCCCCHHHHCCCHHHHHH
VRAVTLAHLAPLPGQVLWDVGAGCGSIGIEWMRSAPSCRAFAIEADAERADVIAHNRAAL
HHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCCCCEEEEEECCCCCHHHEECCCCCC
GVPGLELVEGRAPAVLEGLPDPDAIFIGGGLTANGVFERCWIALKPGGRLVANAVTLESE
CCCCHHHHCCCCCHHHCCCCCCCEEEECCCCCCCCCEEEEEEEECCCCEEEEEEEEECCC
ARLAHWHGVLGGELTRLSVAHADPVGRFHGWRSAMPVTLYEVVKPKQG
CHHHHHHCCCCCCEEEEEEECCCCCHHHCCHHCCCCEEEEHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]