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The map label for this gene is cobK [H]

Identifier: 83594318

GI number: 83594318

Start: 3441006

End: 3441761

Strand: Direct

Name: cobK [H]

Synonym: Rru_A2988

Alternate gene names: 83594318

Gene position: 3441006-3441761 (Clockwise)

Preceding gene: 83594317

Following gene: 83594322

Centisome position: 79.05

GC content: 70.5

Gene sequence:

>756_bases
ATGTCCCTTAGCCTGCTCATTCTCGGTGGAACCAGCGAAGGCTATGCCCTGGCCGCCGCCCTCGACTCCGCGCCTGGCCT
GCGGGTGATCAGTTCCCTGGCCGGACGCACCGCCACCCCGCGCCGCCCGGCGGGGGCCTGTCGAATCGGCGGTTTCGGCG
GCATCGACGGCCTGGGCGCTTATCTGGCGACGGAAAGAATCGACGCGGTGATCGACGCCACCCATCCCTTCGCCAGCACC
ATGGGCTGGAACGCGGCGGCGGCTTGCGACAAGGCCGGGGTGCCGCTGCTGCGCCTGGAGCGTCCGGCTTGGGTGGCCGG
CGATTACGACCGCTGGGCCGAGGTCGATAACTGGCAAGAAGCCGCCGGAATTCTTGATTACGCCGCCAATCGGGTGCTGC
TGGCGCTCGGCCGCCAGGACCTCGACGCCTTCACCCCCTTGCGCCACCTGTGGTTCCTGATCCGCTCGGTCGACGCCCCC
GATCCGCTGCCGCCCTTCGCCCATGCCGAGGTTCTGCTCGCCCGCGGCCCGTTCTCGCTGGACTCGGAACGTGCCCTGCT
CGGCGCGCGGGCCATCGACACCATCGTTTGCAAGAACAGCGGCGGCACCGCCACCGACGCCAAACTGACCGCCGCCCGCG
AATTGGGCCTGCGCGTCATCATGCGCCGCCGCCCCAAACGCCCCCCCCTGCCCACCGCCGCCACCCCGGACGAGGCGGTG
ACCTGGGTGGAGCGCTTGCGGGGAGAGGATCGATAG

Upstream 100 bases:

>100_bases
GGCGGCCTTGCTGCGCTCGGCGGCCGAACGGCGCACCGATCCGCGCGCTCCCTTGGCCGAAAGACCGGGCGTTGATCGCG
ATCTTCCGTGAAGGTTTCCC

Downstream 100 bases:

>100_bases
GGACGGTGGTTAGCCCCGTTCGCTCCCATACCAGCGCGGAGTATAGACCCAGGATCGGCCGTCGGCGCGCGGGAAGCTGC
GGGTTTGTGACGAGCCGATG

Product: precorrin-6A reductase

Products: NA

Alternate protein names: Precorrin-6X reductase [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MSLSLLILGGTSEGYALAAALDSAPGLRVISSLAGRTATPRRPAGACRIGGFGGIDGLGAYLATERIDAVIDATHPFAST
MGWNAAAACDKAGVPLLRLERPAWVAGDYDRWAEVDNWQEAAGILDYAANRVLLALGRQDLDAFTPLRHLWFLIRSVDAP
DPLPPFAHAEVLLARGPFSLDSERALLGARAIDTIVCKNSGGTATDAKLTAARELGLRVIMRRRPKRPPLPTAATPDEAV
TWVERLRGEDR

Sequences:

>Translated_251_residues
MSLSLLILGGTSEGYALAAALDSAPGLRVISSLAGRTATPRRPAGACRIGGFGGIDGLGAYLATERIDAVIDATHPFAST
MGWNAAAACDKAGVPLLRLERPAWVAGDYDRWAEVDNWQEAAGILDYAANRVLLALGRQDLDAFTPLRHLWFLIRSVDAP
DPLPPFAHAEVLLARGPFSLDSERALLGARAIDTIVCKNSGGTATDAKLTAARELGLRVIMRRRPKRPPLPTAATPDEAV
TWVERLRGEDR
>Mature_250_residues
SLSLLILGGTSEGYALAAALDSAPGLRVISSLAGRTATPRRPAGACRIGGFGGIDGLGAYLATERIDAVIDATHPFASTM
GWNAAAACDKAGVPLLRLERPAWVAGDYDRWAEVDNWQEAAGILDYAANRVLLALGRQDLDAFTPLRHLWFLIRSVDAPD
PLPPFAHAEVLLARGPFSLDSERALLGARAIDTIVCKNSGGTATDAKLTAARELGLRVIMRRRPKRPPLPTAATPDEAVT
WVERLRGEDR

Specific function: Catalyzes the reduction of the macrocycle of precorrin- 6X into precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: =1.3.1.54 [H]

Molecular weight: Translated: 26785; Mature: 26654

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSLLILGGTSEGYALAAALDSAPGLRVISSLAGRTATPRRPAGACRIGGFGGIDGLGA
CCEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCEECCCCCCHHHHHH
YLATERIDAVIDATHPFASTMGWNAAAACDKAGVPLLRLERPAWVAGDYDRWAEVDNWQE
HHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHCCCCEEEECCCCEECCCCHHHHCCCCHHH
AAGILDYAANRVLLALGRQDLDAFTPLRHLWFLIRSVDAPDPLPPFAHAEVLLARGPFSL
HHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCC
DSERALLGARAIDTIVCKNSGGTATDAKLTAARELGLRVIMRRRPKRPPLPTAATPDEAV
CCCHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
TWVERLRGEDR
HHHHHHCCCCC
>Mature Secondary Structure 
SLSLLILGGTSEGYALAAALDSAPGLRVISSLAGRTATPRRPAGACRIGGFGGIDGLGA
CEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCEECCCCCCHHHHHH
YLATERIDAVIDATHPFASTMGWNAAAACDKAGVPLLRLERPAWVAGDYDRWAEVDNWQE
HHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHCCCCEEEECCCCEECCCCHHHHCCCCHHH
AAGILDYAANRVLLALGRQDLDAFTPLRHLWFLIRSVDAPDPLPPFAHAEVLLARGPFSL
HHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCC
DSERALLGARAIDTIVCKNSGGTATDAKLTAARELGLRVIMRRRPKRPPLPTAATPDEAV
CCCHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
TWVERLRGEDR
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200543 [H]