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The map label for this gene is pgi

Identifier: 83594279

GI number: 83594279

Start: 3396863

End: 3398506

Strand: Reverse

Name: pgi

Synonym: Rru_A2947

Alternate gene names: 83594279

Gene position: 3398506-3396863 (Counterclockwise)

Preceding gene: 83594280

Following gene: 83594278

Centisome position: 78.08

GC content: 65.39

Gene sequence:

>1644_bases
ATGCCCGATCCCACCACCCTGTCCGCCTGGGCGGCCCTTGCCGCTCACGCTCCGACCTTGAGCGATCAGCCGCTGCGCGT
TCTGTTCGACGCCGATCCCGACCGCTTCGCGCGCTTCCATCTGCGCTTCGAGGATCTGGTGCTCGATTACTCGAAAAACC
GCATCACCGGCGAGACCATGGCGCTGCTGGCCGATCTCGCCCGCCAGAGCGGGGTCGAGGCCCGGCGCGACGCCATGTTC
GCCGGGGAGCCGATCAACACCACCGAGGGCCGCGCCGTTTTGCATGTGGCCCTGCGCGATCCCACCCCCACCCCGGTTCT
CGTCGATGGCGCCGATGTGAAGCCGGCCATCGCCGCCGTTCTCGCCCATATGGAGGCGTTTTCCGAAGCGGTGCGCAGCG
GCGCCTGGACAGGGGCGACCGGCAAGGCGATCACCGATGTCGTCAATATCGGCATCGGCGGCTCGGACCTCGGGCCGGTG
ATGGTGGTCGAGGCGCTCAAGGCCTATGCCAAGCCCGGTCTGAGGGTGCATTTCGTTTCCAATGTCGATGGCACCCATAT
CGCCGAGACGCTGAAGGGGTTGTCGCCGGAGACCACGCTGTTCCTGGTCGCCTCCAAGACCTTCACCACCCAGGAAACCC
TGACCAACGCCCATACGGCGCGCGACTGGCTGGTTGGCGCCCTGGGCGAGCCGGCGGTGGCCCGCCATTTCGCCGCGCTG
TCGACCAACGCCAAGGCGGTCAGCGCCTTTGGCATCGATACCGCCAATATGTTCGAATTCTGGGACTGGGTGGGCGGGCG
CTATTCCCTGTGGTCGGCCATCGGCCTGCCGATCGCCATCAGCGTCGGTTTCGCCAATTTCCGCGCCCTGCTCGATGGCG
CCCATGCCATGGACACCCATTTCCGCGAGGCGCCGATCGAGCGCAATCTGCCGGTGATCCTCGGCCTGCTCGGCGTCTGG
TATGGGGATTTCCTGGGCGCGCGCGCCCAGGCGGTGCTGCCCTATGACCAATATCTGCACCGGCTGGCCGCCTATCTGCA
GCAGGCCGATATGGAAAGCAACGGCAAGCGCACGACCTTGGACGGCAAGACCGTGGCCTACGCCACCGGCGCGGTGCTGT
TTGGCGAGCCCGGCACCAATGGCCAGCATTCCTTCTATCAGCTGATCCACCAGGGAACCTCGCTGATCCCTTGCGATTTC
ATCGCTCCGGCGATCAGCCATAATCCGCTGGGGCGCCACCACGCCATCTTGCTGTCGAACTTCCTGGCCCAGACCGAGGC
GCTGATGCGCGGCAAGACCGAGGCCGAGGCCCGGGCCGAGTTGGCGGCCCAGGGGCTGGCGGGCGAGGCCCTTGAGGCGC
TGCTGCCCCATAAGGTCTTCCCCGGCAATCGGCCGACCAACGCCATCCTGGTCAAACGCCTTGATCCGCGTACCCTTGGC
ATGCTGATCGCCCTTTATGAACACAAGATCCATGTCCAGGCGACGGTGTGGAACATCAACGCCTATGACCAGTGGGGGGT
GGAACTGGGCAAGCAACTGGCCAAGGCGATCCTGCCCGAACTGGAGGACGCGACCATTTCCCCGGCCCATGATAGTTCCA
CCAATGGCCTGATCGCGCTATATAGGGAGTTCAGCGCCGGGTAA

Upstream 100 bases:

>100_bases
TGGCGCGAGCGGCGGGCGATCTTTGCCGTTTGGCCTCCCGTTTGGGCGGGCTGTCGGCTATTGTCAGTGCCGCGCCCCTG
CCTCCGACCCCGGAGATTTC

Downstream 100 bases:

>100_bases
CCCCCAGATGTAGCCCCCAGCGAGAGGGACGCCGATGACGATCCGTTTGTTGCCGCCGGTCCTCGTCAACCGCATCGCCG
CCGGCGAGGTGGTTGAACGT

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI

Number of amino acids: Translated: 547; Mature: 546

Protein sequence:

>547_residues
MPDPTTLSAWAALAAHAPTLSDQPLRVLFDADPDRFARFHLRFEDLVLDYSKNRITGETMALLADLARQSGVEARRDAMF
AGEPINTTEGRAVLHVALRDPTPTPVLVDGADVKPAIAAVLAHMEAFSEAVRSGAWTGATGKAITDVVNIGIGGSDLGPV
MVVEALKAYAKPGLRVHFVSNVDGTHIAETLKGLSPETTLFLVASKTFTTQETLTNAHTARDWLVGALGEPAVARHFAAL
STNAKAVSAFGIDTANMFEFWDWVGGRYSLWSAIGLPIAISVGFANFRALLDGAHAMDTHFREAPIERNLPVILGLLGVW
YGDFLGARAQAVLPYDQYLHRLAAYLQQADMESNGKRTTLDGKTVAYATGAVLFGEPGTNGQHSFYQLIHQGTSLIPCDF
IAPAISHNPLGRHHAILLSNFLAQTEALMRGKTEAEARAELAAQGLAGEALEALLPHKVFPGNRPTNAILVKRLDPRTLG
MLIALYEHKIHVQATVWNINAYDQWGVELGKQLAKAILPELEDATISPAHDSSTNGLIALYREFSAG

Sequences:

>Translated_547_residues
MPDPTTLSAWAALAAHAPTLSDQPLRVLFDADPDRFARFHLRFEDLVLDYSKNRITGETMALLADLARQSGVEARRDAMF
AGEPINTTEGRAVLHVALRDPTPTPVLVDGADVKPAIAAVLAHMEAFSEAVRSGAWTGATGKAITDVVNIGIGGSDLGPV
MVVEALKAYAKPGLRVHFVSNVDGTHIAETLKGLSPETTLFLVASKTFTTQETLTNAHTARDWLVGALGEPAVARHFAAL
STNAKAVSAFGIDTANMFEFWDWVGGRYSLWSAIGLPIAISVGFANFRALLDGAHAMDTHFREAPIERNLPVILGLLGVW
YGDFLGARAQAVLPYDQYLHRLAAYLQQADMESNGKRTTLDGKTVAYATGAVLFGEPGTNGQHSFYQLIHQGTSLIPCDF
IAPAISHNPLGRHHAILLSNFLAQTEALMRGKTEAEARAELAAQGLAGEALEALLPHKVFPGNRPTNAILVKRLDPRTLG
MLIALYEHKIHVQATVWNINAYDQWGVELGKQLAKAILPELEDATISPAHDSSTNGLIALYREFSAG
>Mature_546_residues
PDPTTLSAWAALAAHAPTLSDQPLRVLFDADPDRFARFHLRFEDLVLDYSKNRITGETMALLADLARQSGVEARRDAMFA
GEPINTTEGRAVLHVALRDPTPTPVLVDGADVKPAIAAVLAHMEAFSEAVRSGAWTGATGKAITDVVNIGIGGSDLGPVM
VVEALKAYAKPGLRVHFVSNVDGTHIAETLKGLSPETTLFLVASKTFTTQETLTNAHTARDWLVGALGEPAVARHFAALS
TNAKAVSAFGIDTANMFEFWDWVGGRYSLWSAIGLPIAISVGFANFRALLDGAHAMDTHFREAPIERNLPVILGLLGVWY
GDFLGARAQAVLPYDQYLHRLAAYLQQADMESNGKRTTLDGKTVAYATGAVLFGEPGTNGQHSFYQLIHQGTSLIPCDFI
APAISHNPLGRHHAILLSNFLAQTEALMRGKTEAEARAELAAQGLAGEALEALLPHKVFPGNRPTNAILVKRLDPRTLGM
LIALYEHKIHVQATVWNINAYDQWGVELGKQLAKAILPELEDATISPAHDSSTNGLIALYREFSAG

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family

Homologues:

Organism=Homo sapiens, GI18201905, Length=530, Percent_Identity=61.8867924528302, Blast_Score=685, Evalue=0.0,
Organism=Homo sapiens, GI296080693, Length=530, Percent_Identity=57.7358490566038, Blast_Score=624, Evalue=1e-179,
Organism=Escherichia coli, GI1790457, Length=542, Percent_Identity=63.2841328413284, Blast_Score=711, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71996708, Length=529, Percent_Identity=60.8695652173913, Blast_Score=664, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71996703, Length=529, Percent_Identity=60.8695652173913, Blast_Score=663, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319673, Length=553, Percent_Identity=55.6962025316456, Blast_Score=615, Evalue=1e-177,
Organism=Drosophila melanogaster, GI24651916, Length=530, Percent_Identity=64.1509433962264, Blast_Score=696, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651914, Length=530, Percent_Identity=64.1509433962264, Blast_Score=696, Evalue=0.0,
Organism=Drosophila melanogaster, GI17737445, Length=530, Percent_Identity=64.1509433962264, Blast_Score=696, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): G6PI_RHORT (Q2RQ51)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_428031.1
- ProteinModelPortal:   Q2RQ51
- SMR:   Q2RQ51
- STRING:   Q2RQ51
- GeneID:   3836391
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A2947
- NMPDR:   fig|1085.1.peg.590
- eggNOG:   COG0166
- HOGENOM:   HBG352954
- OMA:   GPKIVSQ
- PhylomeDB:   Q2RQ51
- BioCyc:   RRUB269796:RRU_A2947-MONOMER
- GO:   GO:0005737
- GO:   GO:0006094
- GO:   GO:0006096
- HAMAP:   MF_00473
- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189
- Gene3D:   G3DSA:1.10.1390.10
- PANTHER:   PTHR11469
- PRINTS:   PR00662

Pfam domain/function: PF00342 PGI

EC number: =5.3.1.9

Molecular weight: Translated: 58909; Mature: 58778

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1; PS00174 P_GLUCOSE_ISOMERASE_2; PS51463 P_GLUCOSE_ISOMERASE_3

Important sites: ACT_SITE 352-352 ACT_SITE 383-383 ACT_SITE 511-511

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDPTTLSAWAALAAHAPTLSDQPLRVLFDADPDRFARFHLRFEDLVLDYSKNRITGETM
CCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHEEHHHHHEECCCCCCCHHHH
ALLADLARQSGVEARRDAMFAGEPINTTEGRAVLHVALRDPTPTPVLVDGADVKPAIAAV
HHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCEEEECCCCCHHHHHH
LAHMEAFSEAVRSGAWTGATGKAITDVVNIGIGGSDLGPVMVVEALKAYAKPGLRVHFVS
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEC
NVDGTHIAETLKGLSPETTLFLVASKTFTTQETLTNAHTARDWLVGALGEPAVARHFAAL
CCCCHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
STNAKAVSAFGIDTANMFEFWDWVGGRYSLWSAIGLPIAISVGFANFRALLDGAHAMDTH
CCCCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHCCCEEEEECHHHHHHHHCCCHHHHHH
FREAPIERNLPVILGLLGVWYGDFLGARAQAVLPYDQYLHRLAAYLQQADMESNGKRTTL
HHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCEEEE
DGKTVAYATGAVLFGEPGTNGQHSFYQLIHQGTSLIPCDFIAPAISHNPLGRHHAILLSN
CCCEEEEEECEEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHH
FLAQTEALMRGKTEAEARAELAAQGLAGEALEALLPHKVFPGNRPTNAILVKRLDPRTLG
HHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHH
MLIALYEHKIHVQATVWNINAYDQWGVELGKQLAKAILPELEDATISPAHDSSTNGLIAL
HHHHHHHCEEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEE
YREFSAG
EEHHCCC
>Mature Secondary Structure 
PDPTTLSAWAALAAHAPTLSDQPLRVLFDADPDRFARFHLRFEDLVLDYSKNRITGETM
CCCCHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHEEHHHHHEECCCCCCCHHHH
ALLADLARQSGVEARRDAMFAGEPINTTEGRAVLHVALRDPTPTPVLVDGADVKPAIAAV
HHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCEEEECCCCCHHHHHH
LAHMEAFSEAVRSGAWTGATGKAITDVVNIGIGGSDLGPVMVVEALKAYAKPGLRVHFVS
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEC
NVDGTHIAETLKGLSPETTLFLVASKTFTTQETLTNAHTARDWLVGALGEPAVARHFAAL
CCCCHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
STNAKAVSAFGIDTANMFEFWDWVGGRYSLWSAIGLPIAISVGFANFRALLDGAHAMDTH
CCCCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHCCCEEEEECHHHHHHHHCCCHHHHHH
FREAPIERNLPVILGLLGVWYGDFLGARAQAVLPYDQYLHRLAAYLQQADMESNGKRTTL
HHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCEEEE
DGKTVAYATGAVLFGEPGTNGQHSFYQLIHQGTSLIPCDFIAPAISHNPLGRHHAILLSN
CCCEEEEEECEEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHH
FLAQTEALMRGKTEAEARAELAAQGLAGEALEALLPHKVFPGNRPTNAILVKRLDPRTLG
HHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHH
MLIALYEHKIHVQATVWNINAYDQWGVELGKQLAKAILPELEDATISPAHDSSTNGLIAL
HHHHHHHCEEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEE
YREFSAG
EEHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA