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The map label for this gene is zraS [C]

Identifier: 83594152

GI number: 83594152

Start: 3253365

End: 3255854

Strand: Reverse

Name: zraS [C]

Synonym: Rru_A2820

Alternate gene names: 83594152

Gene position: 3255854-3253365 (Counterclockwise)

Preceding gene: 83594153

Following gene: 83594151

Centisome position: 74.8

GC content: 69.24

Gene sequence:

>2490_bases
ATGAGTGACGCGGTGCTGATTCGCGAGCCGGCCCTGTGGGGGCTGGGGGCGGGCCTGGGCGGGGCGCTGGCGGGCGGCTT
GTGGTCGGCCCTGGGCGAATTGCCGGTGGCCGGCTGGGTGGCGGCGATCGGTGCCACCATCGCCCTGGGATCGCTGGCCG
CCCTGCTGCGCCGCTTCGCCCAATGGGGCGAGGCCGCCGCCCGCGGCGGGGCCGCCGCCGCCTTGCTTGATATCGAAGAC
GGCCCGCGCCTGCTGATCGGCGCCGATGGCGGGGCGCGCTACGCCAATTCCCAGGCCAGAACCCTGTGGGGCGGCCACCC
GCCGCTGGCCCATCTGCGCCAGCGTCTGCATGGCGACATGATGGCCGCCGATGCCCTGGGGCGCTTGGAGGAGGCGGCGC
GCATCGGTCTGCGCGAGGAGGTCGACCTGCCGTTGCGCGATCCCGAAGGCTATAGCGGCGAGCCCGAATGGGTGCGGGTG
ATGGTGGCGCCCGGCCGCGAACCGGGCAGTCGCTTGTGGTCGTGCCGCGATGTCACGGCGCGCCGCGCCATCGACGAGGT
TTTGCTGCGTGAGCGCGAGGAACTGGCCGATTTCCTTTATTTCCTGCCCGTTGGCCTTTATTCGGCCGATACGGATGGCC
GGTTGCGCTACGCCAATCAGGTTTTCGCCCAATGGCTGGGCCGCGATACCGACGCCATGGTCGGCCTGGATATCGACGCG
GTGATGGAAGGCCCGGCCCCCGAACCCGATGGGGCCTGGGAGGGCCGCCTGCGCTTTCTTCCCGTCGACGAGCCGGCTTT
TGACGCCGAGGTGCGCCAATCGACCTTTGATGACGCCGGCCAGCTACGCACCCGATCGGTGGTGGTGCGTCTGCCCGCCG
GCGAGGCCGCGCCGACGGCGGGCGAGGGCGGCTGGCTGCGTCGGCGGCCCTGGCTGTTCGACGGCGCCCCGGTGGGGATC
GTGCTGACCGACCCGGAAGGGGCGATCACCGATTGCAACGCCTCGTTCCTGGCGATGGTCGGGCTGGAGGCGGCCGATGT
CTTTGACCGGCCGCTGGCCGATCTGGCGGCGCGCAACGACCGCGAGGACCTGCGGGCGCTGGTCGACAAGGTGGTGGGCG
GCGGCACCGCCCAGGCCGATATCCGCCTGGTGCGCGGCGAACGCGAGGTGGCCGTCGGCGTGTTCTTGTCGCCGATGACC
AGCCTGAGCGGCCGCCCCGGCGATCCGCCCGATGGCGCGGTCGCCCATCTGATCGACACCACCGAGCAAAAGAACCTGGA
GCAGCAGTTCGCCCAGGCCCAGAAGATGCAGGCGATGGGCCAGCTCGCCGGGGGCGTCGCCCATGATTTCAACAATCTGC
TGACGGCGATGATCGGCTTTTCCGATTTGCTGTTGCAACGCCACGGCATCGGCGATCCCAGTTTCGCCGATATCATGCAG
ATCAAGCAAAACGCCAATCGCGCCGCCAATCTGGTGCGCCAGCTTCTCGCCTTCTCGCGCCGCCAGCCCTTGCGGCCGCG
CTTGCTCAATGTGACCGACGCGCTGTCGGAGCTGTCGCATCTGCTGCGCCGCCTGCTTGGCGAGAGGGTGGTCCTGAAGC
TCGCCCACGGCCGCGAACCCGTCCATATCCGCGTCGATCCCGGCCAGTTCGATCAGGTCATCATCAATCTGGCGGTCAAT
GCCCGCGACGCCATGCCCGGCGGCGGGCAACTGACCATCTCGACCCGGCGCGAGGCGGTCGAGACCGAGATGAACCAGGG
GACCGAGGCGGTGCCGCCCGGGGATTACGTGGTCATTGATGTCGTCGATACCGGCACCGGCATCACCCGCGAGAACCTTG
GTCGGCTGTTCGAGCCGTTCTTCACCACCAAATCGGAAGGAACGGCGGGAGCGGGGACCGGGCTTGGGCTGTCAACCGTT
TACGGCATCGTCCGCCAGACCGAGGGCTTCATCTTCGTCGAATCGACCCTGGGCGAGGGGGCGACCTTCACCATCTATCT
GCCGCGCCACGAGCCGCCCGTCGAGGTCGCCGGAGCGGGCGCCGGCGGGGCCGAGGGCGGAGTGGGGCCGGGCGACGGCG
CGCCGGGCGGGGGCGGCGAGGAAGGGGGCGAGGCCCGCGACCTGACGGGCAAGGAGACCATCTTGCTGGTCGAGGACGAG
GACGCCGTGCGGGTGTTCGGATCGCGGGCCCTGCGCAACAAGGGCTATACGGTGCTCGAAGCCCGCTCGGGCGAAGGCGC
GCTGGATGTGCTCGAGGACGGTGCCGAGATCGACCTGCTGATCACCGATATGGTGATGCCGGGCATGGATGGGGCCACCC
TGGCCGGCCGGGTGCGCGAGGCGCGGCCCGATCTGAAGATCATCCTGATTTCGGGCTATTCCGAGGATGTCATTCGCGGC
GATATCGTCAACCAGCCCGATACCCACTTCCTGCCCAAGCCGTTCAGCCTGAAAGCCCTGGCCGAAAAGGTCCGCGAGGT
TCTGGCGTGA

Upstream 100 bases:

>100_bases
GCCGTCGAGATCGATCATGAAATTCCCCCCGACCACTACAAGGCGGTGGCCGAGGTGATCGGCTATGTCATGCGCCTGAA
GAAGGCGACGAAGAGATAGC

Downstream 100 bases:

>100_bases
ACGGTGATCTTGTTCTGTTCTATTTTGCCCCTTGAATGCGAGAACAAAAAGAGTACGTTTGAGCATGGTTGCGCGTGCGG
GCGCGGCCATGGGATAACGG

Product: multi-sensor hybrid histidine kinase / cell cycle control histidine kinase CckA

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 829; Mature: 828

Protein sequence:

>829_residues
MSDAVLIREPALWGLGAGLGGALAGGLWSALGELPVAGWVAAIGATIALGSLAALLRRFAQWGEAAARGGAAAALLDIED
GPRLLIGADGGARYANSQARTLWGGHPPLAHLRQRLHGDMMAADALGRLEEAARIGLREEVDLPLRDPEGYSGEPEWVRV
MVAPGREPGSRLWSCRDVTARRAIDEVLLREREELADFLYFLPVGLYSADTDGRLRYANQVFAQWLGRDTDAMVGLDIDA
VMEGPAPEPDGAWEGRLRFLPVDEPAFDAEVRQSTFDDAGQLRTRSVVVRLPAGEAAPTAGEGGWLRRRPWLFDGAPVGI
VLTDPEGAITDCNASFLAMVGLEAADVFDRPLADLAARNDREDLRALVDKVVGGGTAQADIRLVRGEREVAVGVFLSPMT
SLSGRPGDPPDGAVAHLIDTTEQKNLEQQFAQAQKMQAMGQLAGGVAHDFNNLLTAMIGFSDLLLQRHGIGDPSFADIMQ
IKQNANRAANLVRQLLAFSRRQPLRPRLLNVTDALSELSHLLRRLLGERVVLKLAHGREPVHIRVDPGQFDQVIINLAVN
ARDAMPGGGQLTISTRREAVETEMNQGTEAVPPGDYVVIDVVDTGTGITRENLGRLFEPFFTTKSEGTAGAGTGLGLSTV
YGIVRQTEGFIFVESTLGEGATFTIYLPRHEPPVEVAGAGAGGAEGGVGPGDGAPGGGGEEGGEARDLTGKETILLVEDE
DAVRVFGSRALRNKGYTVLEARSGEGALDVLEDGAEIDLLITDMVMPGMDGATLAGRVREARPDLKIILISGYSEDVIRG
DIVNQPDTHFLPKPFSLKALAEKVREVLA

Sequences:

>Translated_829_residues
MSDAVLIREPALWGLGAGLGGALAGGLWSALGELPVAGWVAAIGATIALGSLAALLRRFAQWGEAAARGGAAAALLDIED
GPRLLIGADGGARYANSQARTLWGGHPPLAHLRQRLHGDMMAADALGRLEEAARIGLREEVDLPLRDPEGYSGEPEWVRV
MVAPGREPGSRLWSCRDVTARRAIDEVLLREREELADFLYFLPVGLYSADTDGRLRYANQVFAQWLGRDTDAMVGLDIDA
VMEGPAPEPDGAWEGRLRFLPVDEPAFDAEVRQSTFDDAGQLRTRSVVVRLPAGEAAPTAGEGGWLRRRPWLFDGAPVGI
VLTDPEGAITDCNASFLAMVGLEAADVFDRPLADLAARNDREDLRALVDKVVGGGTAQADIRLVRGEREVAVGVFLSPMT
SLSGRPGDPPDGAVAHLIDTTEQKNLEQQFAQAQKMQAMGQLAGGVAHDFNNLLTAMIGFSDLLLQRHGIGDPSFADIMQ
IKQNANRAANLVRQLLAFSRRQPLRPRLLNVTDALSELSHLLRRLLGERVVLKLAHGREPVHIRVDPGQFDQVIINLAVN
ARDAMPGGGQLTISTRREAVETEMNQGTEAVPPGDYVVIDVVDTGTGITRENLGRLFEPFFTTKSEGTAGAGTGLGLSTV
YGIVRQTEGFIFVESTLGEGATFTIYLPRHEPPVEVAGAGAGGAEGGVGPGDGAPGGGGEEGGEARDLTGKETILLVEDE
DAVRVFGSRALRNKGYTVLEARSGEGALDVLEDGAEIDLLITDMVMPGMDGATLAGRVREARPDLKIILISGYSEDVIRG
DIVNQPDTHFLPKPFSLKALAEKVREVLA
>Mature_828_residues
SDAVLIREPALWGLGAGLGGALAGGLWSALGELPVAGWVAAIGATIALGSLAALLRRFAQWGEAAARGGAAAALLDIEDG
PRLLIGADGGARYANSQARTLWGGHPPLAHLRQRLHGDMMAADALGRLEEAARIGLREEVDLPLRDPEGYSGEPEWVRVM
VAPGREPGSRLWSCRDVTARRAIDEVLLREREELADFLYFLPVGLYSADTDGRLRYANQVFAQWLGRDTDAMVGLDIDAV
MEGPAPEPDGAWEGRLRFLPVDEPAFDAEVRQSTFDDAGQLRTRSVVVRLPAGEAAPTAGEGGWLRRRPWLFDGAPVGIV
LTDPEGAITDCNASFLAMVGLEAADVFDRPLADLAARNDREDLRALVDKVVGGGTAQADIRLVRGEREVAVGVFLSPMTS
LSGRPGDPPDGAVAHLIDTTEQKNLEQQFAQAQKMQAMGQLAGGVAHDFNNLLTAMIGFSDLLLQRHGIGDPSFADIMQI
KQNANRAANLVRQLLAFSRRQPLRPRLLNVTDALSELSHLLRRLLGERVVLKLAHGREPVHIRVDPGQFDQVIINLAVNA
RDAMPGGGQLTISTRREAVETEMNQGTEAVPPGDYVVIDVVDTGTGITRENLGRLFEPFFTTKSEGTAGAGTGLGLSTVY
GIVRQTEGFIFVESTLGEGATFTIYLPRHEPPVEVAGAGAGGAEGGVGPGDGAPGGGGEEGGEARDLTGKETILLVEDED
AVRVFGSRALRNKGYTVLEARSGEGALDVLEDGAEIDLLITDMVMPGMDGATLAGRVREARPDLKIILISGYSEDVIRGD
IVNQPDTHFLPKPFSLKALAEKVREVLA

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=244, Percent_Identity=29.9180327868852, Blast_Score=104, Evalue=3e-23,
Organism=Escherichia coli, GI1788549, Length=361, Percent_Identity=27.7008310249307, Blast_Score=102, Evalue=8e-23,
Organism=Escherichia coli, GI1788713, Length=286, Percent_Identity=27.6223776223776, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI145693157, Length=275, Percent_Identity=26.1818181818182, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786600, Length=258, Percent_Identity=26.3565891472868, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1790300, Length=374, Percent_Identity=27.2727272727273, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 88384; Mature: 88253

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDAVLIREPALWGLGAGLGGALAGGLWSALGELPVAGWVAAIGATIALGSLAALLRRFA
CCCCEEEECCCCHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QWGEAAARGGAAAALLDIEDGPRLLIGADGGARYANSQARTLWGGHPPLAHLRQRLHGDM
HHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCEECCCCCCHHHHHHHHCCCH
MAADALGRLEEAARIGLREEVDLPLRDPEGYSGEPEWVRVMVAPGREPGSRLWSCRDVTA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHCCHHHHHH
RRAIDEVLLREREELADFLYFLPVGLYSADTDGRLRYANQVFAQWLGRDTDAMVGLDIDA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCHHH
VMEGPAPEPDGAWEGRLRFLPVDEPAFDAEVRQSTFDDAGQLRTRSVVVRLPAGEAAPTA
HCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHCCHHHHEEEEEEEEECCCCCCCCCC
GEGGWLRRRPWLFDGAPVGIVLTDPEGAITDCNASFLAMVGLEAADVFDRPLADLAARND
CCCCCCCCCCCEECCCCEEEEEECCCCCEECCCCHHHHHHCCCHHHHHHCHHHHHHHCCC
REDLRALVDKVVGGGTAQADIRLVRGEREVAVGVFLSPMTSLSGRPGDPPDGAVAHLIDT
HHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEEEECCHHHCCCCCCCCCCCHHHHHHHC
TEQKNLEQQFAQAQKMQAMGQLAGGVAHDFNNLLTAMIGFSDLLLQRHGIGDPSFADIMQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
IKQNANRAANLVRQLLAFSRRQPLRPRLLNVTDALSELSHLLRRLLGERVVLKLAHGREP
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHCCCCC
VHIRVDPGQFDQVIINLAVNARDAMPGGGQLTISTRREAVETEMNQGTEAVPPGDYVVID
EEEEECCCCCCEEEEEEEECCCCCCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCEEEEE
VVDTGTGITRENLGRLFEPFFTTKSEGTAGAGTGLGLSTVYGIVRQTEGFIFVESTLGEG
EEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCC
ATFTIYLPRHEPPVEVAGAGAGGAEGGVGPGDGAPGGGGEEGGEARDLTGKETILLVEDE
CEEEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECC
DAVRVFGSRALRNKGYTVLEARSGEGALDVLEDGAEIDLLITDMVMPGMDGATLAGRVRE
CHHHHHHHHHHHCCCCEEEEECCCCCCHHHHCCCCCEEEEEEHHHCCCCCCCHHHHHHHH
ARPDLKIILISGYSEDVIRGDIVNQPDTHFLPKPFSLKALAEKVREVLA
CCCCEEEEEEECCCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
>Mature Secondary Structure 
SDAVLIREPALWGLGAGLGGALAGGLWSALGELPVAGWVAAIGATIALGSLAALLRRFA
CCCEEEECCCCHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QWGEAAARGGAAAALLDIEDGPRLLIGADGGARYANSQARTLWGGHPPLAHLRQRLHGDM
HHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCEECCCCCCHHHHHHHHCCCH
MAADALGRLEEAARIGLREEVDLPLRDPEGYSGEPEWVRVMVAPGREPGSRLWSCRDVTA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHCCHHHHHH
RRAIDEVLLREREELADFLYFLPVGLYSADTDGRLRYANQVFAQWLGRDTDAMVGLDIDA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCHHH
VMEGPAPEPDGAWEGRLRFLPVDEPAFDAEVRQSTFDDAGQLRTRSVVVRLPAGEAAPTA
HCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHCCHHHHEEEEEEEEECCCCCCCCCC
GEGGWLRRRPWLFDGAPVGIVLTDPEGAITDCNASFLAMVGLEAADVFDRPLADLAARND
CCCCCCCCCCCEECCCCEEEEEECCCCCEECCCCHHHHHHCCCHHHHHHCHHHHHHHCCC
REDLRALVDKVVGGGTAQADIRLVRGEREVAVGVFLSPMTSLSGRPGDPPDGAVAHLIDT
HHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEEEECCHHHCCCCCCCCCCCHHHHHHHC
TEQKNLEQQFAQAQKMQAMGQLAGGVAHDFNNLLTAMIGFSDLLLQRHGIGDPSFADIMQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
IKQNANRAANLVRQLLAFSRRQPLRPRLLNVTDALSELSHLLRRLLGERVVLKLAHGREP
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHCCCCC
VHIRVDPGQFDQVIINLAVNARDAMPGGGQLTISTRREAVETEMNQGTEAVPPGDYVVID
EEEEECCCCCCEEEEEEEECCCCCCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCEEEEE
VVDTGTGITRENLGRLFEPFFTTKSEGTAGAGTGLGLSTVYGIVRQTEGFIFVESTLGEG
EEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCC
ATFTIYLPRHEPPVEVAGAGAGGAEGGVGPGDGAPGGGGEEGGEARDLTGKETILLVEDE
CEEEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECC
DAVRVFGSRALRNKGYTVLEARSGEGALDVLEDGAEIDLLITDMVMPGMDGATLAGRVRE
CHHHHHHHHHHHCCCCEEEEECCCCCCHHHHCCCCCEEEEEEHHHCCCCCCCHHHHHHHH
ARPDLKIILISGYSEDVIRGDIVNQPDTHFLPKPFSLKALAEKVREVLA
CCCCEEEEEEECCCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA