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The map label for this gene is wecB [H]

Identifier: 83594072

GI number: 83594072

Start: 3171985

End: 3173082

Strand: Reverse

Name: wecB [H]

Synonym: Rru_A2740

Alternate gene names: 83594072

Gene position: 3173082-3171985 (Counterclockwise)

Preceding gene: 83594073

Following gene: 83594071

Centisome position: 72.9

GC content: 65.66

Gene sequence:

>1098_bases
ATGAAAGTCATGACCATTCTGGGCACGCGCCCGGAACTGATCCGCTTGTCGCTGATCCTGCCCAGGCTTGATGCGGTGTG
CGACCATGTTTTCGTCTATACCGGGCAGAACGCCCATCCCAGCCTGTGGCGAAATTTCCTGGGCGAGTTTTCCCTGCGCT
CCGAAGATCACGACCTGGGCGCCAGCCAGGGCACCCTGGGCGAGCGGGTGGGGGCCATCCTTGCCGGGGCGGAACGGGTG
ATCGGTCTGGAACGCCCCGACCGGGTGCTGATCCTTGGCGATACCAACAGCGGTCTGTCGGCCTATGTCGCCAAGCGCCT
GGGCATCCCGGTTTTTCATATGGAGGCGGGAAACCGCTGCCATGACGACCGGGTGCCCGAAGAGGTCAACCGCCGGGTCA
TCGATCATTGCTCCGATCTTTTGATGCCCTATACCGAGCATGGTCGGCGCAATCTGCTGGCCGAGGGCATCCCCGGCCAG
CGCATCGTGGTCACCGGCAATCCCATCGGCGAGGTGCTGGCGGCGATGGCCGAGCGCATCGACGCCGCGACCGCGCTGGG
TGCCCTGGGGCTGCGGCCCGGCGCGTATCTGCTGTTCACCTTCCACCGTCAGGAAAACGTCGATGTTCCCCAGCGCCTAA
TGGCCCTGATGGCCGGGGTGCGGCGGGTGATGGCGGTAAGCGGCCTGCCCGCCGTGGTCAGTGTCCATCCGCGCACCCGC
GCCCATCTCGAGGCGAGCGGTTTGGCCGACCAGGGGCGCGGCGATCTGATGTTGATGGAGCCCTTTGGCTTCTGCGATTT
CGTCGCCCTGGAAAAATCCGCCCGCTGCGTGCTGAGCGATAGCGGCACGGTGCAGGAGGAGGGGGCGATCCTTGGTGTGC
CGACGGTGACGCTGCGCGATGTCACCGAACGGCCCGAGACCCTGGAGACCGGCAGCAATATCCTATGCGGCGTTGATCCC
GAAGCGATGGAGCGGGCCTTTCGCCTGGTGACCGCGACACCACCCAATTGGCCGGTTCCGTTGGACTATACCCGCATGAA
CGTGGCCGACACCGTGGTCCGGCTGCTGATCGGCGCCAGCCTGCCGGTGGGGCGATGA

Upstream 100 bases:

>100_bases
CCCAAGGGGTGCTCGACCGGGCGGGGGTGGAAGAGCTGTTTCGCCGCAATCGCTTGATGGTGGGCGATCTGGACCTGGAT
GACGAGAAAGATCTGCTGCG

Downstream 100 bases:

>100_bases
GCGCCATGGACGCCGAAGACTCTCCGTTCACCGCCCTGGGCGATGAGGCCTGGGAGGCGGGATCCTGGCGCAAGGCCGCC
TTGTTCTATGGCCGGGCGCT

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MKVMTILGTRPELIRLSLILPRLDAVCDHVFVYTGQNAHPSLWRNFLGEFSLRSEDHDLGASQGTLGERVGAILAGAERV
IGLERPDRVLILGDTNSGLSAYVAKRLGIPVFHMEAGNRCHDDRVPEEVNRRVIDHCSDLLMPYTEHGRRNLLAEGIPGQ
RIVVTGNPIGEVLAAMAERIDAATALGALGLRPGAYLLFTFHRQENVDVPQRLMALMAGVRRVMAVSGLPAVVSVHPRTR
AHLEASGLADQGRGDLMLMEPFGFCDFVALEKSARCVLSDSGTVQEEGAILGVPTVTLRDVTERPETLETGSNILCGVDP
EAMERAFRLVTATPPNWPVPLDYTRMNVADTVVRLLIGASLPVGR

Sequences:

>Translated_365_residues
MKVMTILGTRPELIRLSLILPRLDAVCDHVFVYTGQNAHPSLWRNFLGEFSLRSEDHDLGASQGTLGERVGAILAGAERV
IGLERPDRVLILGDTNSGLSAYVAKRLGIPVFHMEAGNRCHDDRVPEEVNRRVIDHCSDLLMPYTEHGRRNLLAEGIPGQ
RIVVTGNPIGEVLAAMAERIDAATALGALGLRPGAYLLFTFHRQENVDVPQRLMALMAGVRRVMAVSGLPAVVSVHPRTR
AHLEASGLADQGRGDLMLMEPFGFCDFVALEKSARCVLSDSGTVQEEGAILGVPTVTLRDVTERPETLETGSNILCGVDP
EAMERAFRLVTATPPNWPVPLDYTRMNVADTVVRLLIGASLPVGR
>Mature_365_residues
MKVMTILGTRPELIRLSLILPRLDAVCDHVFVYTGQNAHPSLWRNFLGEFSLRSEDHDLGASQGTLGERVGAILAGAERV
IGLERPDRVLILGDTNSGLSAYVAKRLGIPVFHMEAGNRCHDDRVPEEVNRRVIDHCSDLLMPYTEHGRRNLLAEGIPGQ
RIVVTGNPIGEVLAAMAERIDAATALGALGLRPGAYLLFTFHRQENVDVPQRLMALMAGVRRVMAVSGLPAVVSVHPRTR
AHLEASGLADQGRGDLMLMEPFGFCDFVALEKSARCVLSDSGTVQEEGAILGVPTVTLRDVTERPETLETGSNILCGVDP
EAMERAFRLVTATPPNWPVPLDYTRMNVADTVVRLLIGASLPVGR

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=354, Percent_Identity=31.0734463276836, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 39686; Mature: 39686

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVMTILGTRPELIRLSLILPRLDAVCDHVFVYTGQNAHPSLWRNFLGEFSLRSEDHDLG
CEEEEEECCCCHHEEHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCC
ASQGTLGERVGAILAGAERVIGLERPDRVLILGDTNSGLSAYVAKRLGIPVFHMEAGNRC
CCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEECCCCCC
HDDRVPEEVNRRVIDHCSDLLMPYTEHGRRNLLAEGIPGQRIVVTGNPIGEVLAAMAERI
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHH
DAATALGALGLRPGAYLLFTFHRQENVDVPQRLMALMAGVRRVMAVSGLPAVVSVHPRTR
HHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHH
AHLEASGLADQGRGDLMLMEPFGFCDFVALEKSARCVLSDSGTVQEEGAILGVPTVTLRD
HHEECCCCCCCCCCCEEEECCCCCHHHHHHCCCCCEEECCCCCCCCCCCEEECCCEEEHH
VTERPETLETGSNILCGVDPEAMERAFRLVTATPPNWPVPLDYTRMNVADTVVRLLIGAS
HHCCCCHHHCCCCEEECCCHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCC
LPVGR
CCCCC
>Mature Secondary Structure
MKVMTILGTRPELIRLSLILPRLDAVCDHVFVYTGQNAHPSLWRNFLGEFSLRSEDHDLG
CEEEEEECCCCHHEEHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCC
ASQGTLGERVGAILAGAERVIGLERPDRVLILGDTNSGLSAYVAKRLGIPVFHMEAGNRC
CCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEECCCCCC
HDDRVPEEVNRRVIDHCSDLLMPYTEHGRRNLLAEGIPGQRIVVTGNPIGEVLAAMAERI
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHH
DAATALGALGLRPGAYLLFTFHRQENVDVPQRLMALMAGVRRVMAVSGLPAVVSVHPRTR
HHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHH
AHLEASGLADQGRGDLMLMEPFGFCDFVALEKSARCVLSDSGTVQEEGAILGVPTVTLRD
HHEECCCCCCCCCCCEEEECCCCCHHHHHHCCCCCEEECCCCCCCCCCCEEECCCEEEHH
VTERPETLETGSNILCGVDPEAMERAFRLVTATPPNWPVPLDYTRMNVADTVVRLLIGAS
HHCCCCHHHCCCCEEECCCHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCC
LPVGR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]