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The map label for this gene is cph2 [H]

Identifier: 83593993

GI number: 83593993

Start: 3090356

End: 3092290

Strand: Reverse

Name: cph2 [H]

Synonym: Rru_A2661

Alternate gene names: 83593993

Gene position: 3092290-3090356 (Counterclockwise)

Preceding gene: 83593994

Following gene: 83593992

Centisome position: 71.04

GC content: 67.86

Gene sequence:

>1935_bases
ATGGGGGCGGAGGGCGCTTCGCTCGACGACGCGGACACTCCCTCGATGGCGGCCCAGGCGGCGGCTCGTCTGAGTGTGCT
TGGGCTGCTGATCGTTGGGCTGGTCAGTCTCGTCGGCTATTTTTTCGTTTTCGACTGGGACAAGACGCAGGCCCTTGAGC
GGCTGAGCGATTTCCTGGTCCAACGCCGTGCCCTGGAAAACACCCTGTTTGACGAGGCCCAGCGCAACGGCGAGCGGTTC
CACGCGCTGTTCCTGGACGACTATCACGGCGCTCCGCCCCTTGATGAGGCCGAATTCGGCCGCTATTTCCAGCAAGACGG
CACGGACGGCCCCTGGCGAACGCGGCCGGAGTTCTATCACGGCCTGCGCGACCGGGAAGGCGGGCTCATCGCCGGGGTCT
CGGGCTTCATCGCCGCCGGTCGCGGAGCGGTGGCGCCCGATCACGCCCGCCGGCTGGTCGTGTCGATGCGCTTGTTGGGG
CGTCTTGGCCCGGCGTGGAGCGGGGCTTTCGCCAATTCCACGATTTCGACGCCGGAAAACGGCAGCCTGCTTTATTGGCC
GGGGGTGCCCTGGGGGCTGGAGGCCGCCGCCGATTTGCGCCCGGCCGAGGGATCGGTCATCGCCTCGACCTTGGTCGAGC
ATAATCCGCAGCGGCGCCCGGTCTGGACGGCGCTGTATCACGATCTGACCGCCGATGCCTGGACAGTGACCTATCAGCGT
CCGATCGACGAGGACGGACGTCATCTTGTCACCTTCGGCCATGACCTGCTGCTCAACGCCATGCTCAACCGGCTGGCCTC
CGACCATCCGCCGGGGGCCAGCAGCTTTTTGCTGGGCGCCGATGGCAGCCTGATCGCCCATGCCGGCAGCGAGGAGCGCA
TGGCCCATATCGGTACCCAGATCGATCTGGAGACCCTGGGCGATCCGGCGCTGCTTCGGCGCTATCGGCTGCTGGTCGCC
GCCGTTGGTCAGAGGGGGGGCGACGGCGTGTGGATGGTCGAGGATCGCGAGGACCACGCCTGGTTGGCGGCCACGGAGCT
GTCGGGACCGGGCTGGTGGTACGTGATTTCCTACCCCAAGGAGGTCATCGCCGATCGCGCCCGGCGGGCGGCCAATCAGG
TGGTGATCGGCGGGGTGGTCTTGTCGTTCCTGCTGGTCGCCATGGTGCAACTGGTGATGCGGCGGCGGGTGGCGCGGCCG
CTGGCCCAATTGGCGCGGGCGGCCGGCGCGGTGGGTACCGGACAGACCGCTCTGGTGGCCAGTGGCGGGCTTGACCTGCC
GATCGGCGAGCGCAACGAAATCGGTGTGCTGGCCCGGGCCTTCCGCGAGATGGCGATGCGGGTGCGCGATCACGAGGTTA
TTCTGGAACGCGAGATCGCCAATCGGACGGGGGCCTTGGAAGAGGCGAACCGCCGTCTGCATTCGTTGAGCGAGACCGAT
GGTCTGACCGGGCTGTTCAATCGTCGCGCCCTGGATCGCGATCTGGCCGGCCACTGCGCCCTGGCGCGCGGCGGCGGCGG
GGCCGTGGCCCTGATCATGGTCGATATCGATTATTTCAAAGCCTATAACGACGCCGAGGGGCATCTGGCCGGCGACGACG
CCTTGCGCAAGGTCGCCCAACGCCTGCTTTCCATCCTGCGCCCCGGTGATACCATCTATCGCTATGGCGGCGAGGAGATG
GCCGTGCTGATCGGTGGCGCCGGGGCCGACGGCGCCGTCGGTGTCGCCCGGCGCATCGTCGATGAGGTGGCGGCCCTGGC
CATTCCCCATCCGGCCAGCCCCTTTGGCGTCATCACGCTGAGCGCCGGTCTGGCGGTGCTTCGCGGTGAGGCCACCCTGC
CCAAGACCTTGATCAGTCGCGCCGATGAGCAGCTTTACGCCGCCAAGCGCGGCGGCCGCAATGTCCTGGTCGTCGCCCCG
ACCGATCCCGCTTGA

Upstream 100 bases:

>100_bases
GAGGGCGGCGTCGTCTTTAGGTCTTTGGGCTTCATTCAGGCCTTTCGGATTGACCGTCCCTGGGATAGGGTCGGTCCTTT
CGAACAGGGATAGGTCGGTC

Downstream 100 bases:

>100_bases
TCTCGGCGGCCGGGCGGGGTTTGCTGCGCCCTTGAGGCAGCCGGGCGGAAGGGTTTAAAGGGATGACCAAGGGATTGTTC
GACGAGGCCGCCCCCCGGCC

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 644; Mature: 643

Protein sequence:

>644_residues
MGAEGASLDDADTPSMAAQAAARLSVLGLLIVGLVSLVGYFFVFDWDKTQALERLSDFLVQRRALENTLFDEAQRNGERF
HALFLDDYHGAPPLDEAEFGRYFQQDGTDGPWRTRPEFYHGLRDREGGLIAGVSGFIAAGRGAVAPDHARRLVVSMRLLG
RLGPAWSGAFANSTISTPENGSLLYWPGVPWGLEAAADLRPAEGSVIASTLVEHNPQRRPVWTALYHDLTADAWTVTYQR
PIDEDGRHLVTFGHDLLLNAMLNRLASDHPPGASSFLLGADGSLIAHAGSEERMAHIGTQIDLETLGDPALLRRYRLLVA
AVGQRGGDGVWMVEDREDHAWLAATELSGPGWWYVISYPKEVIADRARRAANQVVIGGVVLSFLLVAMVQLVMRRRVARP
LAQLARAAGAVGTGQTALVASGGLDLPIGERNEIGVLARAFREMAMRVRDHEVILEREIANRTGALEEANRRLHSLSETD
GLTGLFNRRALDRDLAGHCALARGGGGAVALIMVDIDYFKAYNDAEGHLAGDDALRKVAQRLLSILRPGDTIYRYGGEEM
AVLIGGAGADGAVGVARRIVDEVAALAIPHPASPFGVITLSAGLAVLRGEATLPKTLISRADEQLYAAKRGGRNVLVVAP
TDPA

Sequences:

>Translated_644_residues
MGAEGASLDDADTPSMAAQAAARLSVLGLLIVGLVSLVGYFFVFDWDKTQALERLSDFLVQRRALENTLFDEAQRNGERF
HALFLDDYHGAPPLDEAEFGRYFQQDGTDGPWRTRPEFYHGLRDREGGLIAGVSGFIAAGRGAVAPDHARRLVVSMRLLG
RLGPAWSGAFANSTISTPENGSLLYWPGVPWGLEAAADLRPAEGSVIASTLVEHNPQRRPVWTALYHDLTADAWTVTYQR
PIDEDGRHLVTFGHDLLLNAMLNRLASDHPPGASSFLLGADGSLIAHAGSEERMAHIGTQIDLETLGDPALLRRYRLLVA
AVGQRGGDGVWMVEDREDHAWLAATELSGPGWWYVISYPKEVIADRARRAANQVVIGGVVLSFLLVAMVQLVMRRRVARP
LAQLARAAGAVGTGQTALVASGGLDLPIGERNEIGVLARAFREMAMRVRDHEVILEREIANRTGALEEANRRLHSLSETD
GLTGLFNRRALDRDLAGHCALARGGGGAVALIMVDIDYFKAYNDAEGHLAGDDALRKVAQRLLSILRPGDTIYRYGGEEM
AVLIGGAGADGAVGVARRIVDEVAALAIPHPASPFGVITLSAGLAVLRGEATLPKTLISRADEQLYAAKRGGRNVLVVAP
TDPA
>Mature_643_residues
GAEGASLDDADTPSMAAQAAARLSVLGLLIVGLVSLVGYFFVFDWDKTQALERLSDFLVQRRALENTLFDEAQRNGERFH
ALFLDDYHGAPPLDEAEFGRYFQQDGTDGPWRTRPEFYHGLRDREGGLIAGVSGFIAAGRGAVAPDHARRLVVSMRLLGR
LGPAWSGAFANSTISTPENGSLLYWPGVPWGLEAAADLRPAEGSVIASTLVEHNPQRRPVWTALYHDLTADAWTVTYQRP
IDEDGRHLVTFGHDLLLNAMLNRLASDHPPGASSFLLGADGSLIAHAGSEERMAHIGTQIDLETLGDPALLRRYRLLVAA
VGQRGGDGVWMVEDREDHAWLAATELSGPGWWYVISYPKEVIADRARRAANQVVIGGVVLSFLLVAMVQLVMRRRVARPL
AQLARAAGAVGTGQTALVASGGLDLPIGERNEIGVLARAFREMAMRVRDHEVILEREIANRTGALEEANRRLHSLSETDG
LTGLFNRRALDRDLAGHCALARGGGGAVALIMVDIDYFKAYNDAEGHLAGDDALRKVAQRLLSILRPGDTIYRYGGEEMA
VLIGGAGADGAVGVARRIVDEVAALAIPHPASPFGVITLSAGLAVLRGEATLPKTLISRADEQLYAAKRGGRNVLVVAPT
DPA

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=174, Percent_Identity=35.0574712643678, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI145693134, Length=155, Percent_Identity=36.1290322580645, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1787816, Length=158, Percent_Identity=38.6075949367089, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1787541, Length=183, Percent_Identity=35.5191256830601, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1787262, Length=170, Percent_Identity=35.2941176470588, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI87081881, Length=178, Percent_Identity=34.8314606741573, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788381, Length=181, Percent_Identity=33.1491712707182, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI87082007, Length=158, Percent_Identity=38.6075949367089, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1787056, Length=169, Percent_Identity=33.7278106508876, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081977, Length=181, Percent_Identity=30.3867403314917, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI87081974, Length=153, Percent_Identity=28.7581699346405, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 69324; Mature: 69192

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS50885 HAMP ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAEGASLDDADTPSMAAQAAARLSVLGLLIVGLVSLVGYFFVFDWDKTQALERLSDFLV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHH
QRRALENTLFDEAQRNGERFHALFLDDYHGAPPLDEAEFGRYFQQDGTDGPWRTRPEFYH
HHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHH
GLRDREGGLIAGVSGFIAAGRGAVAPDHARRLVVSMRLLGRLGPAWSGAFANSTISTPEN
CCCCCCCCEEECCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GSLLYWPGVPWGLEAAADLRPAEGSVIASTLVEHNPQRRPVWTALYHDLTADAWTVTYQR
CCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEEEEC
PIDEDGRHLVTFGHDLLLNAMLNRLASDHPPGASSFLLGADGSLIAHAGSEERMAHIGTQ
CCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEECCCHHHHHHHCCE
IDLETLGDPALLRRYRLLVAAVGQRGGDGVWMVEDREDHAWLAATELSGPGWWYVISYPK
EEHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEECCCCCEEEEECCCH
EVIADRARRAANQVVIGGVVLSFLLVAMVQLVMRRRVARPLAQLARAAGAVGTGQTALVA
HHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
SGGLDLPIGERNEIGVLARAFREMAMRVRDHEVILEREIANRTGALEEANRRLHSLSETD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
GLTGLFNRRALDRDLAGHCALARGGGGAVALIMVDIDYFKAYNDAEGHLAGDDALRKVAQ
CCHHHHHHHHHHHHHHCCEEEEECCCCEEEEEEEEEHHHHCCCCCCCCCCCHHHHHHHHH
RLLSILRPGDTIYRYGGEEMAVLIGGAGADGAVGVARRIVDEVAALAIPHPASPFGVITL
HHHHHHCCCCCEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
SAGLAVLRGEATLPKTLISRADEQLYAAKRGGRNVLVVAPTDPA
CCCHHEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
>Mature Secondary Structure 
GAEGASLDDADTPSMAAQAAARLSVLGLLIVGLVSLVGYFFVFDWDKTQALERLSDFLV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHH
QRRALENTLFDEAQRNGERFHALFLDDYHGAPPLDEAEFGRYFQQDGTDGPWRTRPEFYH
HHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHH
GLRDREGGLIAGVSGFIAAGRGAVAPDHARRLVVSMRLLGRLGPAWSGAFANSTISTPEN
CCCCCCCCEEECCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GSLLYWPGVPWGLEAAADLRPAEGSVIASTLVEHNPQRRPVWTALYHDLTADAWTVTYQR
CCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEEEEC
PIDEDGRHLVTFGHDLLLNAMLNRLASDHPPGASSFLLGADGSLIAHAGSEERMAHIGTQ
CCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEECCCHHHHHHHCCE
IDLETLGDPALLRRYRLLVAAVGQRGGDGVWMVEDREDHAWLAATELSGPGWWYVISYPK
EEHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEECCCCCEEEEECCCH
EVIADRARRAANQVVIGGVVLSFLLVAMVQLVMRRRVARPLAQLARAAGAVGTGQTALVA
HHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
SGGLDLPIGERNEIGVLARAFREMAMRVRDHEVILEREIANRTGALEEANRRLHSLSETD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
GLTGLFNRRALDRDLAGHCALARGGGGAVALIMVDIDYFKAYNDAEGHLAGDDALRKVAQ
CCHHHHHHHHHHHHHHCCEEEEECCCCEEEEEEEEEHHHHCCCCCCCCCCCHHHHHHHHH
RLLSILRPGDTIYRYGGEEMAVLIGGAGADGAVGVARRIVDEVAALAIPHPASPFGVITL
HHHHHHCCCCCEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
SAGLAVLRGEATLPKTLISRADEQLYAAKRGGRNVLVVAPTDPA
CCCHHEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]