Click here to switch to the map view.

The map label for this gene is gmhA

Identifier: 83593937

GI number: 83593937

Start: 3029883

End: 3030449

Strand: Reverse

Name: gmhA

Synonym: Rru_A2605

Alternate gene names: 83593937

Gene position: 3030449-3029883 (Counterclockwise)

Preceding gene: 83593938

Following gene: 83593936

Centisome position: 69.62

GC content: 65.78

Gene sequence:

>567_bases
GTGGAAGACGAGATCAGGGCTTTTTGTCAGACCGCCGCCGATTGTTTCATCCGCCTGGGGGACTGCGCGCCGGCCATCGC
CGAGGCGGCGGGGGTGGTGACGGCCAGCCTGCGCGCCGGCGGCAAGGTGATGTTCTGCGGCAATGGCGGGTCGGCCGCCG
ATGCCCAGCATCTGGCAGCGGAACTGGAGGGCCGCTATCTGAAGGAACGGGCGCCGTTGCCCGGGATGGCGCTGACCACC
AACACCTCGACCCTTACCGCCGTCGGCAATGATTACGGCTTCGATCATATCTTTTCGCGTCAAGTCAGCGCCCATGGCCG
TCCCGGCGATGTGCTGGTCGCCCTGTCGACCAGCGGCAACAGCGCCAATGTGCTGAAGGCGATCGAGGCGGCGCGGGAAA
AGGGCGTTTCGGTCATCGGTCTGACCGGGGCGGGGGGCGGCAAGATGGCCGAGGTCTGCGATCTGTGCATCAGGGTTCCC
TCGACGCAGACGCCGCAGATCCAGCAGATGCATATCGCCGTTGGCCACCTGCTGTGCGGTTTGGTCGAGGACGCCTTATG
CTCGTGA

Upstream 100 bases:

>100_bases
TTGACAGCGGCAAGGCGCCTTTGAGTGATGAGGACTGGTCAAGGACCGGCCGGGCGGGTATCAGAAATGGCTTTGCCACA
CCTGCTTATGGGACCAGACC

Downstream 100 bases:

>100_bases
GGCCGAGGGGAGGGCGGATGATCTTTCCGCCGATCTAGACGAATTGTTGGGGTGGGTTAAGAAAATCAGTTAGAGTGGGG
CTTGTGGTGGCGCCTGATCC

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MEDEIRAFCQTAADCFIRLGDCAPAIAEAAGVVTASLRAGGKVMFCGNGGSAADAQHLAAELEGRYLKERAPLPGMALTT
NTSTLTAVGNDYGFDHIFSRQVSAHGRPGDVLVALSTSGNSANVLKAIEAAREKGVSVIGLTGAGGGKMAEVCDLCIRVP
STQTPQIQQMHIAVGHLLCGLVEDALCS

Sequences:

>Translated_188_residues
MEDEIRAFCQTAADCFIRLGDCAPAIAEAAGVVTASLRAGGKVMFCGNGGSAADAQHLAAELEGRYLKERAPLPGMALTT
NTSTLTAVGNDYGFDHIFSRQVSAHGRPGDVLVALSTSGNSANVLKAIEAAREKGVSVIGLTGAGGGKMAEVCDLCIRVP
STQTPQIQQMHIAVGHLLCGLVEDALCS
>Mature_188_residues
MEDEIRAFCQTAADCFIRLGDCAPAIAEAAGVVTASLRAGGKVMFCGNGGSAADAQHLAAELEGRYLKERAPLPGMALTT
NTSTLTAVGNDYGFDHIFSRQVSAHGRPGDVLVALSTSGNSANVLKAIEAAREKGVSVIGLTGAGGGKMAEVCDLCIRVP
STQTPQIQQMHIAVGHLLCGLVEDALCS

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1786416, Length=191, Percent_Identity=49.738219895288, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI1789539, Length=190, Percent_Identity=40.5263157894737, Blast_Score=145, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GMHA_RHORT (Q2RR43)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_427689.1
- ProteinModelPortal:   Q2RR43
- SMR:   Q2RR43
- STRING:   Q2RR43
- GeneID:   3836040
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A2605
- NMPDR:   fig|1085.1.peg.256
- eggNOG:   COG0279
- HOGENOM:   HBG671955
- OMA:   QEMHILI
- PhylomeDB:   Q2RR43
- ProtClustDB:   CLSK2397398
- BioCyc:   RRUB269796:RRU_A2605-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00067
- InterPro:   IPR004515
- InterPro:   IPR020620
- InterPro:   IPR001347
- TIGRFAMs:   TIGR00441

Pfam domain/function: PF01380 SIS

EC number: =5.3.1.28

Molecular weight: Translated: 19316; Mature: 19316

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS51464 SIS

Important sites: BINDING 61-61 BINDING 121-121 BINDING 168-168

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDEIRAFCQTAADCFIRLGDCAPAIAEAAGVVTASLRAGGKVMFCGNGGSAADAQHLAA
CCHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHEEECCCCCEEEEECCCCCCHHHHHHHH
ELEGRYLKERAPLPGMALTTNTSTLTAVGNDYGFDHIFSRQVSAHGRPGDVLVALSTSGN
HHHCHHHHHCCCCCCEEEEECCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCC
SANVLKAIEAAREKGVSVIGLTGAGGGKMAEVCDLCIRVPSTQTPQIQQMHIAVGHLLCG
CHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
LVEDALCS
HHHHHHCC
>Mature Secondary Structure
MEDEIRAFCQTAADCFIRLGDCAPAIAEAAGVVTASLRAGGKVMFCGNGGSAADAQHLAA
CCHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHEEECCCCCEEEEECCCCCCHHHHHHHH
ELEGRYLKERAPLPGMALTTNTSTLTAVGNDYGFDHIFSRQVSAHGRPGDVLVALSTSGN
HHHCHHHHHCCCCCCEEEEECCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCC
SANVLKAIEAAREKGVSVIGLTGAGGGKMAEVCDLCIRVPSTQTPQIQQMHIAVGHLLCG
CHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
LVEDALCS
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA