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The map label for this gene is yhcK [H]

Identifier: 83593925

GI number: 83593925

Start: 3013148

End: 3014857

Strand: Reverse

Name: yhcK [H]

Synonym: Rru_A2593

Alternate gene names: 83593925

Gene position: 3014857-3013148 (Counterclockwise)

Preceding gene: 83593926

Following gene: 83593923

Centisome position: 69.26

GC content: 55.91

Gene sequence:

>1710_bases
ATGGTGTGTCTCGCCACCCCGGCCACCGCGCAGGGGCGGGGCGAGGATCTGGTCGTCTCGCGCGCTTATATCGAGGATCC
CGGCGGTGTCCTGAGCATCGACGATGTCGTGTCGCGCGCGGCCGTTCCCTTTGACGCGGTCTTGTCGAAGGGCTTCAGCG
CGTCGGTCTATTGGGTTCGCCTAAGGGTGCGGGCGCCTGAAGCGGGCGCTCGGACGGTCTTGCTGATCAGTCCGAGTTTT
CTCAACGATGTGCGCCTTTTTCGGCGTGATCCCAAGGCCGCCCAGGGATGGGAAGTCCGGGTGACGGGAAACCTACATCC
TTTCGCCGAGCGGGAGCGCAAGGCCGTCTCCCTCAGCTTTGTCGTTGGCGTCTCTCCGCCGCAAGAGGATTTTTATTTCC
GTATAAAAACCAGAAGCCCAATGACTTTCGAGGTGCAGGCTCTCTCAGTGGAGGATGCCAATGAGCAAGATTATTGGCGG
GACATTATCGAAGTTTTCTTTGTAACATCCATGGTCTTATTATTGATTTGGGGCGTTCATCAATATTTTATAGATAAGCA
GAAAATTTTAATTTTATTTTGTATTTATCAGATAGTTTATACATTGTATGGTATCGCTTTGACGGGGTATTTCGCTTCCT
TATCGACGCGGTTTTTTCCAGAGTTGATCGACCTGATTAACGCCATAATATATATATCTGCCGTGCTAACATCTGTTTTG
TTTTGTCGTGAAATTTTCAGACCCTATAAGCCTCATCCGCTTCTTATGAAGGGATTTTTGGTTTTTATTTTGGCCTTTCC
TTTTCAGATGATCGCCATGGTGGCGGGATATTCTGATTTGGCGATCATCAGTGCCGCTTTGTTGATGAAGCTGGCCGTTT
TCTATTACGTCATCGTCGCTTTTTCCCTTAAGAAAGATCTGTTCCCGACGAGAAACATGCTGAGGCTGTTTTTCCTGTCG
ATGGCGGTGGCCAATGGGGCGTTCTGGGCCGGCGCGCGGTTGGTTGACGATGTGCGGGCGATGAGCCTGATCGGGGTTCA
GTCGTTGATCGTCGACGGTTTTGTCGTCGGCGTCTTCTTCGCGTGGCTGGTGCATGGTCGGAGCCAGTACGGCCGCCGGG
AAACCGAACGGCAATTGCACATGATCCGGCAAGCCTATGAGGTCGAGCAGGAGCGCAAGAGGCAGGCCGAGTGGGAGGCG
CGAACCGATTTCCTGACCGGGCTTTTGAATCGGCGCTCTTTTGTCGATCTGGCCGAGAGGGAACTGGCCCGCTCGCTGCG
CTATCAGCGACCGTTCACCTTGCTGATGATCGACGTCGATCATTTCAAGGCGGTCAACGACACCCGGGGTCATCTTGTCG
GCGATGTGGTTTTGCAAAACGTCGCGCGGCGGATCAAGGAGACCTTGCGCCTGATCGATATCTTTGGCCGCACCGGGGGC
GAGGAATTCGCCGCCGTGATCGTCGAGACGGGCGGGCCCGAGGCCCTGGAGATCGCGCGGCGGCTTTGCGCCGTGGTGGC
CCGGGACGAGATCGTTCAGCCAGAGGGCGAGCCGATCGGCGTGACCATCTCGATCGGCCTTACCCGGTCGAATGGTCGAT
CCATCTCCTTTAGCGCCCTGATGAACGAGGCCGATCAGGCCCTGTATGCGGCCAAACGGGCCGGGCGCAATCAGGTGGTG
ATCAGTCAGCAGGCCTTGGGCGCGCCCTGA

Upstream 100 bases:

>100_bases
GGCTTGAAAAGGATCGCGGCGTGGTCGCCGCCCGTCCCGGCGTTCGATCCTGAGCCGCTTGCCCCTGGCTGTCCTGGCGG
GCCTTTGGGGTCTGCTGGCG

Downstream 100 bases:

>100_bases
GGCGGGGCGACCAGGAGCGGCCCGAGGAAGGTTTGATCGTCGACCTCGCGGAGCGCCCGGGTCGGGCGGCCTTCGGGGCT
TAGGAAGCCATGGGCGGCGA

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 569; Mature: 569

Protein sequence:

>569_residues
MVCLATPATAQGRGEDLVVSRAYIEDPGGVLSIDDVVSRAAVPFDAVLSKGFSASVYWVRLRVRAPEAGARTVLLISPSF
LNDVRLFRRDPKAAQGWEVRVTGNLHPFAERERKAVSLSFVVGVSPPQEDFYFRIKTRSPMTFEVQALSVEDANEQDYWR
DIIEVFFVTSMVLLLIWGVHQYFIDKQKILILFCIYQIVYTLYGIALTGYFASLSTRFFPELIDLINAIIYISAVLTSVL
FCREIFRPYKPHPLLMKGFLVFILAFPFQMIAMVAGYSDLAIISAALLMKLAVFYYVIVAFSLKKDLFPTRNMLRLFFLS
MAVANGAFWAGARLVDDVRAMSLIGVQSLIVDGFVVGVFFAWLVHGRSQYGRRETERQLHMIRQAYEVEQERKRQAEWEA
RTDFLTGLLNRRSFVDLAERELARSLRYQRPFTLLMIDVDHFKAVNDTRGHLVGDVVLQNVARRIKETLRLIDIFGRTGG
EEFAAVIVETGGPEALEIARRLCAVVARDEIVQPEGEPIGVTISIGLTRSNGRSISFSALMNEADQALYAAKRAGRNQVV
ISQQALGAP

Sequences:

>Translated_569_residues
MVCLATPATAQGRGEDLVVSRAYIEDPGGVLSIDDVVSRAAVPFDAVLSKGFSASVYWVRLRVRAPEAGARTVLLISPSF
LNDVRLFRRDPKAAQGWEVRVTGNLHPFAERERKAVSLSFVVGVSPPQEDFYFRIKTRSPMTFEVQALSVEDANEQDYWR
DIIEVFFVTSMVLLLIWGVHQYFIDKQKILILFCIYQIVYTLYGIALTGYFASLSTRFFPELIDLINAIIYISAVLTSVL
FCREIFRPYKPHPLLMKGFLVFILAFPFQMIAMVAGYSDLAIISAALLMKLAVFYYVIVAFSLKKDLFPTRNMLRLFFLS
MAVANGAFWAGARLVDDVRAMSLIGVQSLIVDGFVVGVFFAWLVHGRSQYGRRETERQLHMIRQAYEVEQERKRQAEWEA
RTDFLTGLLNRRSFVDLAERELARSLRYQRPFTLLMIDVDHFKAVNDTRGHLVGDVVLQNVARRIKETLRLIDIFGRTGG
EEFAAVIVETGGPEALEIARRLCAVVARDEIVQPEGEPIGVTISIGLTRSNGRSISFSALMNEADQALYAAKRAGRNQVV
ISQQALGAP
>Mature_569_residues
MVCLATPATAQGRGEDLVVSRAYIEDPGGVLSIDDVVSRAAVPFDAVLSKGFSASVYWVRLRVRAPEAGARTVLLISPSF
LNDVRLFRRDPKAAQGWEVRVTGNLHPFAERERKAVSLSFVVGVSPPQEDFYFRIKTRSPMTFEVQALSVEDANEQDYWR
DIIEVFFVTSMVLLLIWGVHQYFIDKQKILILFCIYQIVYTLYGIALTGYFASLSTRFFPELIDLINAIIYISAVLTSVL
FCREIFRPYKPHPLLMKGFLVFILAFPFQMIAMVAGYSDLAIISAALLMKLAVFYYVIVAFSLKKDLFPTRNMLRLFFLS
MAVANGAFWAGARLVDDVRAMSLIGVQSLIVDGFVVGVFFAWLVHGRSQYGRRETERQLHMIRQAYEVEQERKRQAEWEA
RTDFLTGLLNRRSFVDLAERELARSLRYQRPFTLLMIDVDHFKAVNDTRGHLVGDVVLQNVARRIKETLRLIDIFGRTGG
EEFAAVIVETGGPEALEIARRLCAVVARDEIVQPEGEPIGVTISIGLTRSNGRSISFSALMNEADQALYAAKRAGRNQVV
ISQQALGAP

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI145693134, Length=168, Percent_Identity=39.2857142857143, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI87082007, Length=171, Percent_Identity=38.5964912280702, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1786584, Length=172, Percent_Identity=35.4651162790698, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1787262, Length=163, Percent_Identity=36.8098159509202, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87081881, Length=174, Percent_Identity=39.0804597701149, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1787816, Length=168, Percent_Identity=33.9285714285714, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1788085, Length=184, Percent_Identity=33.695652173913, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1788381, Length=188, Percent_Identity=35.6382978723404, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1787802, Length=172, Percent_Identity=31.3953488372093, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787541, Length=191, Percent_Identity=27.2251308900524, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081974, Length=175, Percent_Identity=28, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787056, Length=160, Percent_Identity=35.625, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081977, Length=227, Percent_Identity=27.7533039647577, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 64071; Mature: 64071

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: PS00063 ALDOKETO_REDUCTASE_3 ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVCLATPATAQGRGEDLVVSRAYIEDPGGVLSIDDVVSRAAVPFDAVLSKGFSASVYWVR
CEEECCCCCCCCCCCCEEEEEEEECCCCCEEEHHHHHHHHCCCHHHHHHCCCCCEEEEEE
LRVRAPEAGARTVLLISPSFLNDVRLFRRDPKAAQGWEVRVTGNLHPFAERERKAVSLSF
EEEECCCCCCCEEEEECCHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHCCEEEEEE
VVGVSPPQEDFYFRIKTRSPMTFEVQALSVEDANEQDYWRDIIEVFFVTSMVLLLIWGVH
EEECCCCCCCEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QYFIDKQKILILFCIYQIVYTLYGIALTGYFASLSTRFFPELIDLINAIIYISAVLTSVL
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FCREIFRPYKPHPLLMKGFLVFILAFPFQMIAMVAGYSDLAIISAALLMKLAVFYYVIVA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
FSLKKDLFPTRNMLRLFFLSMAVANGAFWAGARLVDDVRAMSLIGVQSLIVDGFVVGVFF
HHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWLVHGRSQYGRRETERQLHMIRQAYEVEQERKRQAEWEARTDFLTGLLNRRSFVDLAER
HHHHHCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ELARSLRYQRPFTLLMIDVDHFKAVNDTRGHLVGDVVLQNVARRIKETLRLIDIFGRTGG
HHHHHHHCCCCEEEEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EEFAAVIVETGGPEALEIARRLCAVVARDEIVQPEGEPIGVTISIGLTRSNGRSISFSAL
CCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCEEEHHHH
MNEADQALYAAKRAGRNQVVISQQALGAP
HHHHHHHHHHHHHCCCCEEEEEHHCCCCC
>Mature Secondary Structure
MVCLATPATAQGRGEDLVVSRAYIEDPGGVLSIDDVVSRAAVPFDAVLSKGFSASVYWVR
CEEECCCCCCCCCCCCEEEEEEEECCCCCEEEHHHHHHHHCCCHHHHHHCCCCCEEEEEE
LRVRAPEAGARTVLLISPSFLNDVRLFRRDPKAAQGWEVRVTGNLHPFAERERKAVSLSF
EEEECCCCCCCEEEEECCHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHCCEEEEEE
VVGVSPPQEDFYFRIKTRSPMTFEVQALSVEDANEQDYWRDIIEVFFVTSMVLLLIWGVH
EEECCCCCCCEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QYFIDKQKILILFCIYQIVYTLYGIALTGYFASLSTRFFPELIDLINAIIYISAVLTSVL
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FCREIFRPYKPHPLLMKGFLVFILAFPFQMIAMVAGYSDLAIISAALLMKLAVFYYVIVA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
FSLKKDLFPTRNMLRLFFLSMAVANGAFWAGARLVDDVRAMSLIGVQSLIVDGFVVGVFF
HHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWLVHGRSQYGRRETERQLHMIRQAYEVEQERKRQAEWEARTDFLTGLLNRRSFVDLAER
HHHHHCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ELARSLRYQRPFTLLMIDVDHFKAVNDTRGHLVGDVVLQNVARRIKETLRLIDIFGRTGG
HHHHHHHCCCCEEEEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EEFAAVIVETGGPEALEIARRLCAVVARDEIVQPEGEPIGVTISIGLTRSNGRSISFSAL
CCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCEEEHHHH
MNEADQALYAAKRAGRNQVVISQQALGAP
HHHHHHHHHHHHHCCCCEEEEEHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]