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The map label for this gene is ygcA [C]

Identifier: 83593442

GI number: 83593442

Start: 2442015

End: 2443412

Strand: Direct

Name: ygcA [C]

Synonym: Rru_A2107

Alternate gene names: 83593442

Gene position: 2442015-2443412 (Clockwise)

Preceding gene: 83593428

Following gene: 83593448

Centisome position: 56.1

GC content: 74.03

Gene sequence:

>1398_bases
ATGACCGCCGCCCCGCGTAAGTCCCGTAAGCGCCCCTCCTCCTCGCCCCTCGAGGCCATCGTCCATGCCCTGGGGGATCG
CGGCGATGGTCTGGCCCGTCCGGCAAGCGGCGGCGAGCGCTTGTTCTATGTCGCCGGGGCCCTGCCCGGCGAGCGGGTTC
GCCTGCGCCCCCAGGGCCGCAAGGGCGACGGCGAGATCGCCGAGCTGGAGGCCGTGATCGAGGCCAGCGCCGAGCGCGTC
GATCCCCCCTGCCCCCATGCCGCGCTCTGTGGCGGCTGCGATCTTCAGCACCTCGACCCGCCCGCCCTGGCGGACTGGAA
GCGCGACAAGGTGGTGCGCGCCCTGGCCCATCGCGGGCTGGGCACGGTCACCGTCGACCAGACGCTCAGCCTGCCCGCTG
GCACCCGGCGCCGGCTGTCGGTGGGCCTGCGCGGCCGCGCCCGTCACGGAGTCTGCGGCTTCTTCGCCCGCGAAAGCCAC
CGGCTGATCGACACCCCCCACTGTTTGCTGCCCACCCCGCCGCTGGCGGCGCTGATGGAGCACCTGCGCCGCGCCCTGCC
CGGTTTTCTGGCCCCGGCGGCCGAGGGCACGGCCCTGATGACCGAAACCGAGACCGGCATCGACCTGCGCCTTGATCTGC
CGACCGCGCCCGAACTGACCGGGCGCGAGGCCCTGGCCGCCCTGGCCGAGGACGCCGATCTCGCCCGGCTGACCCTGACC
ATCGCCGGTGGATCGGAAGAACCCGTCGCCCTGCGCCGCGCCCCCAAGCTGACTTTGGGCGGAACGCCGGTTCTGCCGCC
GCCCGGTCCCTTCCTTCAGCCCAGCGTTGACGGAGAGCGGGCCCTGACCGATCTGGTGCTTGCCGCCTTCGAGGACTTGC
CCGCCGGCGCGGTGATCGCTGATCTGTTCTGTGGCCTGGGAACCTTCGCCCTGCCGCTGGCCGCCCGGGGCTTCAAGCTG
CGCGGCTGGGATATCGAAAGCTCGGCCATCGGCGCGCTTGGCGCCACCGCCCCGGCCCGGGCCGGCAAGGTCCAGGCCAC
CACCCGCGACCTCTTCCGCCGACCGCTGGTCGCCGAGGAATTGGCGGGATGGTCGGGGGTCGTTCTCGATCCGCCGCGCG
CCGGAGCCAAGGCCCAGGTCGAAGCCCTGGCGGCGGCCGGTCCGGGCCCGCTTGGCGCCCCGGTGCGGCCGAGCATTCTG
GGGATCGTCGGCGGAGCGCCGGCGGCGGCGGCGACCGGCCCCTCGGTCATCGTCCTGGTGTCGTGCGCCCCGGCCAGCTT
CGCCCGCGACGCCCGCGCCCTGGTCGATGGTGGCTATCGCATCGACTGGGTGCGCCCGGTCGACCAGTTCACCTGGTCCC
ACCACGTCGAGGTCGTCGCCCGCTTCAGCCGGGGCTGA

Upstream 100 bases:

>100_bases
AATAAATTAGAGCGGTACCCCCCGCGGAAAAGCCGCCATCGGCCGTTCCGCTTGCCGCTTTAGCCATATCACCTCCTTTT
GTCGATGGATTTCCCCAAGA

Downstream 100 bases:

>100_bases
CCGCGCGACGCCGGCCTCCCGCCCTTTCGGGGGAGGGAGGCCGCTCTCGGATCTTGATAATCAAGCACCCCGTCGGCGCG
CTCTGCTCCAGAGCGCTGGG

Product: 23S rRNA (uracil-5-)-methyltransferase RumA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MTAAPRKSRKRPSSSPLEAIVHALGDRGDGLARPASGGERLFYVAGALPGERVRLRPQGRKGDGEIAELEAVIEASAERV
DPPCPHAALCGGCDLQHLDPPALADWKRDKVVRALAHRGLGTVTVDQTLSLPAGTRRRLSVGLRGRARHGVCGFFARESH
RLIDTPHCLLPTPPLAALMEHLRRALPGFLAPAAEGTALMTETETGIDLRLDLPTAPELTGREALAALAEDADLARLTLT
IAGGSEEPVALRRAPKLTLGGTPVLPPPGPFLQPSVDGERALTDLVLAAFEDLPAGAVIADLFCGLGTFALPLAARGFKL
RGWDIESSAIGALGATAPARAGKVQATTRDLFRRPLVAEELAGWSGVVLDPPRAGAKAQVEALAAAGPGPLGAPVRPSIL
GIVGGAPAAAATGPSVIVLVSCAPASFARDARALVDGGYRIDWVRPVDQFTWSHHVEVVARFSRG

Sequences:

>Translated_465_residues
MTAAPRKSRKRPSSSPLEAIVHALGDRGDGLARPASGGERLFYVAGALPGERVRLRPQGRKGDGEIAELEAVIEASAERV
DPPCPHAALCGGCDLQHLDPPALADWKRDKVVRALAHRGLGTVTVDQTLSLPAGTRRRLSVGLRGRARHGVCGFFARESH
RLIDTPHCLLPTPPLAALMEHLRRALPGFLAPAAEGTALMTETETGIDLRLDLPTAPELTGREALAALAEDADLARLTLT
IAGGSEEPVALRRAPKLTLGGTPVLPPPGPFLQPSVDGERALTDLVLAAFEDLPAGAVIADLFCGLGTFALPLAARGFKL
RGWDIESSAIGALGATAPARAGKVQATTRDLFRRPLVAEELAGWSGVVLDPPRAGAKAQVEALAAAGPGPLGAPVRPSIL
GIVGGAPAAAATGPSVIVLVSCAPASFARDARALVDGGYRIDWVRPVDQFTWSHHVEVVARFSRG
>Mature_464_residues
TAAPRKSRKRPSSSPLEAIVHALGDRGDGLARPASGGERLFYVAGALPGERVRLRPQGRKGDGEIAELEAVIEASAERVD
PPCPHAALCGGCDLQHLDPPALADWKRDKVVRALAHRGLGTVTVDQTLSLPAGTRRRLSVGLRGRARHGVCGFFARESHR
LIDTPHCLLPTPPLAALMEHLRRALPGFLAPAAEGTALMTETETGIDLRLDLPTAPELTGREALAALAEDADLARLTLTI
AGGSEEPVALRRAPKLTLGGTPVLPPPGPFLQPSVDGERALTDLVLAAFEDLPAGAVIADLFCGLGTFALPLAARGFKLR
GWDIESSAIGALGATAPARAGKVQATTRDLFRRPLVAEELAGWSGVVLDPPRAGAKAQVEALAAAGPGPLGAPVRPSILG
IVGGAPAAAATGPSVIVLVSCAPASFARDARALVDGGYRIDWVRPVDQFTWSHHVEVVARFSRG

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RNA M5U methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789148, Length=472, Percent_Identity=27.3305084745763, Blast_Score=116, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR010280 [H]

Pfam domain/function: PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 48454; Mature: 48323

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: PS50926 TRAM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAPRKSRKRPSSSPLEAIVHALGDRGDGLARPASGGERLFYVAGALPGERVRLRPQGR
CCCCCCCHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCCC
KGDGEIAELEAVIEASAERVDPPCPHAALCGGCDLQHLDPPALADWKRDKVVRALAHRGL
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
GTVTVDQTLSLPAGTRRRLSVGLRGRARHGVCGFFARESHRLIDTPHCLLPTPPLAALME
CEEEECCEECCCCCCCCEEEECCCCCCCCCEEEHHHCCCCCEECCCCCCCCCCHHHHHHH
HLRRALPGFLAPAAEGTALMTETETGIDLRLDLPTAPELTGREALAALAEDADLARLTLT
HHHHHCCHHHCCCCCCCEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEE
IAGGSEEPVALRRAPKLTLGGTPVLPPPGPFLQPSVDGERALTDLVLAAFEDLPAGAVIA
EECCCCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHH
DLFCGLGTFALPLAARGFKLRGWDIESSAIGALGATAPARAGKVQATTRDLFRRPLVAEE
HHHHHHHHHHHHHHHCCCEEECCCCCCHHHCCCCCCCCCCCCCEEHHHHHHHHCCHHHHH
LAGWSGVVLDPPRAGAKAQVEALAAAGPGPLGAPVRPSILGIVGGAPAAAATGPSVIVLV
HCCCCCEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEEE
SCAPASFARDARALVDGGYRIDWVRPVDQFTWSHHVEVVARFSRG
EECCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TAAPRKSRKRPSSSPLEAIVHALGDRGDGLARPASGGERLFYVAGALPGERVRLRPQGR
CCCCCCHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCCC
KGDGEIAELEAVIEASAERVDPPCPHAALCGGCDLQHLDPPALADWKRDKVVRALAHRGL
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
GTVTVDQTLSLPAGTRRRLSVGLRGRARHGVCGFFARESHRLIDTPHCLLPTPPLAALME
CEEEECCEECCCCCCCCEEEECCCCCCCCCEEEHHHCCCCCEECCCCCCCCCCHHHHHHH
HLRRALPGFLAPAAEGTALMTETETGIDLRLDLPTAPELTGREALAALAEDADLARLTLT
HHHHHCCHHHCCCCCCCEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEE
IAGGSEEPVALRRAPKLTLGGTPVLPPPGPFLQPSVDGERALTDLVLAAFEDLPAGAVIA
EECCCCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHH
DLFCGLGTFALPLAARGFKLRGWDIESSAIGALGATAPARAGKVQATTRDLFRRPLVAEE
HHHHHHHHHHHHHHHCCCEEECCCCCCHHHCCCCCCCCCCCCCEEHHHHHHHHCCHHHHH
LAGWSGVVLDPPRAGAKAQVEALAAAGPGPLGAPVRPSILGIVGGAPAAAATGPSVIVLV
HCCCCCEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEEE
SCAPASFARDARALVDGGYRIDWVRPVDQFTWSHHVEVVARFSRG
EECCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA