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The map label for this gene is mcpA [H]

Identifier: 83593413

GI number: 83593413

Start: 2406209

End: 2407894

Strand: Direct

Name: mcpA [H]

Synonym: Rru_A2078

Alternate gene names: 83593413

Gene position: 2406209-2407894 (Clockwise)

Preceding gene: 83593411

Following gene: 83593415

Centisome position: 55.28

GC content: 64.53

Gene sequence:

>1686_bases
ATGACTTCTCTGAACAATCTCTCTGTTGGCCGCAAGCTTATCCTGGTCTTCTCGATCATCTTTCTTATGGTAGCGGGATT
GGGAAGTTTCGCCATCAAGGCGTTGTCCGATATGAACAGGGCAGCGACCGATGTTACGGAAACGCGGCTTCCCGCCGTCG
AAAAAGCCCGCAGCCTGCAATTCCTGGTCTCTAGTCTGCGGACCAATCAGATGGCCTATATGGTCGCCCAGGGCGACGAC
TTCGATGCCACCCGCGAGGCCGTCGAGACCATCGAAGAAGTCGTTTACGACACCCGCGAATCGTATGAAAAGCTGATGTC
CTCGCCCGAGGAACGCGAGGCCTATGGCGTCTTTACCGATAATTTCGCCGGCTTCTCGGCCGGTATGACCCGCATCGCCC
AACTCAGCCAGGCGGGACGGATCGACGAGGCCCGCGCTTTGACCTGGGGCGAGACCCAGCCGTTTTATCTGGCTTTGGTC
CAATCGACCGACCGCCTGACCGAATTGAGCCAGACCCAGGCCGCCAAGGCTTCGGCGAATATCGACCACACCAACAAGGT
CGCCCGCATCGGCATCATCGCCGCCTTGATCGCCGTTCTGATCATCGCCGCCATCGCCGGCGCGCTGCTGCGCCAGACCA
TCGCCGCCCCGCTGCTGGCGCTGCGCGGAACCATGGAGCGTCTGGCCCGCGACGACACGGCCGTCGAGATCCCCGGCCAC
GAGCGCAAGGACGAGGTTGGCGCCATGGCCCGCGCCGTCCTGGTCTTCAAGGACGGCATGATCGAAAGCGAAAGGCTGCG
GGCGCGCGAAAACGCCGAGCGCATCGGCAAGGAGGAGCGGGCCAACACCCTGGCCGTTCTGACCCACGACTTCGACACCC
AGGCCAGCTCGGTGATCAATGATGTCGCCGAGGCCGCCGGCGCCATGCAAGTCACCGCCTCGCAGCTGACGCAGGCGGCC
GACAGCACCGCCGAGCAAAGCACCGCCGTCGCCGCCGCCGCCCAAGAGGCTTCGACCAATGTGCAGACCGTCGCCGCCGC
CGCCGAGGAACTGACCTCGTCGATCGGCGAGATCAGCCGCCAGATCGCCCAGGCTTCCCAGGTCAGCCAGAAGGCGGTCG
ATCAGGCGGCCCATACCACCGGCATCGTCGGCGGCCTGGAACAGGCGGCCAAACGCATTGGCGAGGTTGTCGCCATGATC
AACGACATCGCCAGCCAGACCAATCTTCTGGCGCTGAACGCGACGATCGAGGCGGCGCGGGCCGGCGACGCCGGCAAGGG
CTTCGCCGTCGTCGCCGGCGAGGTGAAGTCGCTGGCCAATCAGACGGCGCGGGCGACCGACGATATCACCCAGCAGATCG
GCTCGGTGCAGACGGCGACCGGAGCGGCGGTCGAGGCGATCAATGAAATCGCCACGACCATCGGCGAAATCAACGAGATT
TCGGCCAATATCGCCGCGGCGATGGAACAGCAAGGCGCCGCGACCCAGGAAATCGCCCGCAACGTCGAACAGGCGGCGAC
CGGAACCGATCAGGTGACCCGCAACATTCACGGGGTGAACCGGACCGTCGATGATACGGGGCACTCCGCCCAAGAGGTTC
TTAACGCCGCCACCCGGCTGCGCGACGAATCCGCGGCCATGCAGACGCTGGTGACCACCTTCCTCGACAAGGTCCGCGCC
CTGTAA

Upstream 100 bases:

>100_bases
CCAAAGAATCGGCGCACCACGCGATCCCTTTGAAATTAGATCAAATACAGTCCTATTTCTGCGTAGCTGAGCTGATTATC
GTAACAAAATCGGGGGGCAC

Downstream 100 bases:

>100_bases
GGCCAAGGCCCGCGCCGCCGTCCCGACCGAGGCGAGATCGGCAGGGCGGCGCGGGGCCGACGTCAGACGTTAAGCAGCAA
GTATTCGCGTTCCCAGCTTG

Product: chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 561; Mature: 560

Protein sequence:

>561_residues
MTSLNNLSVGRKLILVFSIIFLMVAGLGSFAIKALSDMNRAATDVTETRLPAVEKARSLQFLVSSLRTNQMAYMVAQGDD
FDATREAVETIEEVVYDTRESYEKLMSSPEEREAYGVFTDNFAGFSAGMTRIAQLSQAGRIDEARALTWGETQPFYLALV
QSTDRLTELSQTQAAKASANIDHTNKVARIGIIAALIAVLIIAAIAGALLRQTIAAPLLALRGTMERLARDDTAVEIPGH
ERKDEVGAMARAVLVFKDGMIESERLRARENAERIGKEERANTLAVLTHDFDTQASSVINDVAEAAGAMQVTASQLTQAA
DSTAEQSTAVAAAAQEASTNVQTVAAAAEELTSSIGEISRQIAQASQVSQKAVDQAAHTTGIVGGLEQAAKRIGEVVAMI
NDIASQTNLLALNATIEAARAGDAGKGFAVVAGEVKSLANQTARATDDITQQIGSVQTATGAAVEAINEIATTIGEINEI
SANIAAAMEQQGAATQEIARNVEQAATGTDQVTRNIHGVNRTVDDTGHSAQEVLNAATRLRDESAAMQTLVTTFLDKVRA
L

Sequences:

>Translated_561_residues
MTSLNNLSVGRKLILVFSIIFLMVAGLGSFAIKALSDMNRAATDVTETRLPAVEKARSLQFLVSSLRTNQMAYMVAQGDD
FDATREAVETIEEVVYDTRESYEKLMSSPEEREAYGVFTDNFAGFSAGMTRIAQLSQAGRIDEARALTWGETQPFYLALV
QSTDRLTELSQTQAAKASANIDHTNKVARIGIIAALIAVLIIAAIAGALLRQTIAAPLLALRGTMERLARDDTAVEIPGH
ERKDEVGAMARAVLVFKDGMIESERLRARENAERIGKEERANTLAVLTHDFDTQASSVINDVAEAAGAMQVTASQLTQAA
DSTAEQSTAVAAAAQEASTNVQTVAAAAEELTSSIGEISRQIAQASQVSQKAVDQAAHTTGIVGGLEQAAKRIGEVVAMI
NDIASQTNLLALNATIEAARAGDAGKGFAVVAGEVKSLANQTARATDDITQQIGSVQTATGAAVEAINEIATTIGEINEI
SANIAAAMEQQGAATQEIARNVEQAATGTDQVTRNIHGVNRTVDDTGHSAQEVLNAATRLRDESAAMQTLVTTFLDKVRA
L
>Mature_560_residues
TSLNNLSVGRKLILVFSIIFLMVAGLGSFAIKALSDMNRAATDVTETRLPAVEKARSLQFLVSSLRTNQMAYMVAQGDDF
DATREAVETIEEVVYDTRESYEKLMSSPEEREAYGVFTDNFAGFSAGMTRIAQLSQAGRIDEARALTWGETQPFYLALVQ
STDRLTELSQTQAAKASANIDHTNKVARIGIIAALIAVLIIAAIAGALLRQTIAAPLLALRGTMERLARDDTAVEIPGHE
RKDEVGAMARAVLVFKDGMIESERLRARENAERIGKEERANTLAVLTHDFDTQASSVINDVAEAAGAMQVTASQLTQAAD
STAEQSTAVAAAAQEASTNVQTVAAAAEELTSSIGEISRQIAQASQVSQKAVDQAAHTTGIVGGLEQAAKRIGEVVAMIN
DIASQTNLLALNATIEAARAGDAGKGFAVVAGEVKSLANQTARATDDITQQIGSVQTATGAAVEAINEIATTIGEINEIS
ANIAAAMEQQGAATQEIARNVEQAATGTDQVTRNIHGVNRTVDDTGHSAQEVLNAATRLRDESAAMQTLVTTFLDKVRAL

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=204, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788194, Length=199, Percent_Identity=35.1758793969849, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1787690, Length=196, Percent_Identity=35.7142857142857, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI2367378, Length=412, Percent_Identity=25.7281553398058, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1789453, Length=221, Percent_Identity=32.579185520362, Blast_Score=92, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59318; Mature: 59187

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLNNLSVGRKLILVFSIIFLMVAGLGSFAIKALSDMNRAATDVTETRLPAVEKARSLQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
FLVSSLRTNQMAYMVAQGDDFDATREAVETIEEVVYDTRESYEKLMSSPEEREAYGVFTD
HHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCC
NFAGFSAGMTRIAQLSQAGRIDEARALTWGETQPFYLALVQSTDRLTELSQTQAAKASAN
CCCCHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
IDHTNKVARIGIIAALIAVLIIAAIAGALLRQTIAAPLLALRGTMERLARDDTAVEIPGH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCC
ERKDEVGAMARAVLVFKDGMIESERLRARENAERIGKEERANTLAVLTHDFDTQASSVIN
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHCCEEEEEEECCCHHHHHHHH
DVAEAAGAMQVTASQLTQAADSTAEQSTAVAAAAQEASTNVQTVAAAAEELTSSIGEISR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
QIAQASQVSQKAVDQAAHTTGIVGGLEQAAKRIGEVVAMINDIASQTNLLALNATIEAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHH
AGDAGKGFAVVAGEVKSLANQTARATDDITQQIGSVQTATGAAVEAINEIATTIGEINEI
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
SANIAAAMEQQGAATQEIARNVEQAATGTDQVTRNIHGVNRTVDDTGHSAQEVLNAATRL
HHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
RDESAAMQTLVTTFLDKVRAL
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSLNNLSVGRKLILVFSIIFLMVAGLGSFAIKALSDMNRAATDVTETRLPAVEKARSLQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
FLVSSLRTNQMAYMVAQGDDFDATREAVETIEEVVYDTRESYEKLMSSPEEREAYGVFTD
HHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCC
NFAGFSAGMTRIAQLSQAGRIDEARALTWGETQPFYLALVQSTDRLTELSQTQAAKASAN
CCCCHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
IDHTNKVARIGIIAALIAVLIIAAIAGALLRQTIAAPLLALRGTMERLARDDTAVEIPGH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCC
ERKDEVGAMARAVLVFKDGMIESERLRARENAERIGKEERANTLAVLTHDFDTQASSVIN
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHCCEEEEEEECCCHHHHHHHH
DVAEAAGAMQVTASQLTQAADSTAEQSTAVAAAAQEASTNVQTVAAAAEELTSSIGEISR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
QIAQASQVSQKAVDQAAHTTGIVGGLEQAAKRIGEVVAMINDIASQTNLLALNATIEAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHH
AGDAGKGFAVVAGEVKSLANQTARATDDITQQIGSVQTATGAAVEAINEIATTIGEINEI
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
SANIAAAMEQQGAATQEIARNVEQAATGTDQVTRNIHGVNRTVDDTGHSAQEVLNAATRL
HHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
RDESAAMQTLVTTFLDKVRAL
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]