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The map label for this gene is potC [H]

Identifier: 83593380

GI number: 83593380

Start: 2364850

End: 2365677

Strand: Reverse

Name: potC [H]

Synonym: Rru_A2045

Alternate gene names: 83593380

Gene position: 2365677-2364850 (Counterclockwise)

Preceding gene: 83593381

Following gene: 83593379

Centisome position: 54.35

GC content: 64.98

Gene sequence:

>828_bases
ATGCGCTCTACCCATACCCGCACCGGCGAGGAAAAGTTCTGGATCACCCTGTTATGGGTCGGCGCCGTCGGCGTGCTGGT
CTTCCTGATGGCGCCGATCCTGGCGATCATTCCGCTGTCGTTCAACGGCGGTCAGTTCCTGACCTATCCGCTTCAGGGGT
TTTCCTTGCGCTGGTACGCGGCCTTCCTCACCGATCCGGTGTGGATCCGCGCCCTGCGCAACAGCCTGATCATCGGCATC
GTCTCGACCATCCTGGCCACCGGCCTTGGCACCTTGGCCTCGCTGGGTCTGGTGCGGGCGAAGTTCCGGGGCAAGGGGCT
GGTGATGGCGGTCTTGCTGTCGCCGATGATCGTGCCGGTGGTGATCACCGCCGTCGGCTTCTATCTGTTTTTCGCGCCCT
TGGGGCTGACGGCCAATTATCCCGGGCTGATCCTGGCCCATACGGTGCTGGCCGCCCCCTTCGTCGTCATCTCGGTGACG
GCGACCCTTCAGGGGTTCGACATGAACCTTGCCCGCGCCGCAGCCAGCCTGGGCGCCGATCAGGTAACCACCTTCCGCCG
GGTTATTTTGCCGTTGATCGCGCCGGGCGTCGCCTCGGGCGCCTTGTTCGCCTTCGCCACGTCGTTTGACGAGGTGGTGG
TGGTCTTGCTGGTCGCCGGCCCCGAACAGCGGACCTTGCCGCGCGAAATGTTCAGCGGCATCCGCGAAAACATCAGCCCG
ACGATCACCGCCGTCGCCACCGTGCTGATCTTGTTCTCGACCCTTCTGCTGATCGCCCTCGAAGCCCTGCGCCGGCGCAA
CGAACGCATGCGCGGACTGGCGGGGTAG

Upstream 100 bases:

>100_bases
TACGCCGTCTATACCCGGCTGGTCGGTACGGATTCGGTGAAGCTGTCTTAAAATCGCCAGGGGATTGTCTCCAAGTCCCT
GGATCCCGGGAGGCCCGATC

Downstream 100 bases:

>100_bases
GGGGCGTTTCTTGCTCTGAAAACCGCGTCATCGGCGGGCCGGACGCTTGGGCGCGCCTTGTGATATCGTTCTTTAGCAGA
CGGGGAGCGACGCGCATGAC

Product: binding-protein dependent transport system inner membrane protein

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MRSTHTRTGEEKFWITLLWVGAVGVLVFLMAPILAIIPLSFNGGQFLTYPLQGFSLRWYAAFLTDPVWIRALRNSLIIGI
VSTILATGLGTLASLGLVRAKFRGKGLVMAVLLSPMIVPVVITAVGFYLFFAPLGLTANYPGLILAHTVLAAPFVVISVT
ATLQGFDMNLARAAASLGADQVTTFRRVILPLIAPGVASGALFAFATSFDEVVVVLLVAGPEQRTLPREMFSGIRENISP
TITAVATVLILFSTLLLIALEALRRRNERMRGLAG

Sequences:

>Translated_275_residues
MRSTHTRTGEEKFWITLLWVGAVGVLVFLMAPILAIIPLSFNGGQFLTYPLQGFSLRWYAAFLTDPVWIRALRNSLIIGI
VSTILATGLGTLASLGLVRAKFRGKGLVMAVLLSPMIVPVVITAVGFYLFFAPLGLTANYPGLILAHTVLAAPFVVISVT
ATLQGFDMNLARAAASLGADQVTTFRRVILPLIAPGVASGALFAFATSFDEVVVVLLVAGPEQRTLPREMFSGIRENISP
TITAVATVLILFSTLLLIALEALRRRNERMRGLAG
>Mature_275_residues
MRSTHTRTGEEKFWITLLWVGAVGVLVFLMAPILAIIPLSFNGGQFLTYPLQGFSLRWYAAFLTDPVWIRALRNSLIIGI
VSTILATGLGTLASLGLVRAKFRGKGLVMAVLLSPMIVPVVITAVGFYLFFAPLGLTANYPGLILAHTVLAAPFVVISVT
ATLQGFDMNLARAAASLGADQVTTFRRVILPLIAPGVASGALFAFATSFDEVVVVLLVAGPEQRTLPREMFSGIRENISP
TITAVATVLILFSTLLLIALEALRRRNERMRGLAG

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=236, Percent_Identity=34.3220338983051, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1787081, Length=230, Percent_Identity=33.9130434782609, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787714, Length=252, Percent_Identity=31.3492063492063, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1788764, Length=226, Percent_Identity=26.5486725663717, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29539; Mature: 29539

Theoretical pI: Translated: 11.50; Mature: 11.50

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSTHTRTGEEKFWITLLWVGAVGVLVFLMAPILAIIPLSFNGGQFLTYPLQGFSLRWYA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHH
AFLTDPVWIRALRNSLIIGIVSTILATGLGTLASLGLVRAKFRGKGLVMAVLLSPMIVPV
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VITAVGFYLFFAPLGLTANYPGLILAHTVLAAPFVVISVTATLQGFDMNLARAAASLGAD
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHH
QVTTFRRVILPLIAPGVASGALFAFATSFDEVVVVLLVAGPEQRTLPREMFSGIRENISP
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEHEECCCCCCCCHHHHHHHHHHCCCH
TITAVATVLILFSTLLLIALEALRRRNERMRGLAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRSTHTRTGEEKFWITLLWVGAVGVLVFLMAPILAIIPLSFNGGQFLTYPLQGFSLRWYA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHH
AFLTDPVWIRALRNSLIIGIVSTILATGLGTLASLGLVRAKFRGKGLVMAVLLSPMIVPV
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VITAVGFYLFFAPLGLTANYPGLILAHTVLAAPFVVISVTATLQGFDMNLARAAASLGAD
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHH
QVTTFRRVILPLIAPGVASGALFAFATSFDEVVVVLLVAGPEQRTLPREMFSGIRENISP
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEHEECCCCCCCCHHHHHHHHHHCCCH
TITAVATVLILFSTLLLIALEALRRRNERMRGLAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]