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The map label for this gene is nac [H]

Identifier: 83593339

GI number: 83593339

Start: 2315101

End: 2316015

Strand: Reverse

Name: nac [H]

Synonym: Rru_A2004

Alternate gene names: 83593339

Gene position: 2316015-2315101 (Counterclockwise)

Preceding gene: 83593342

Following gene: 83593338

Centisome position: 53.21

GC content: 72.02

Gene sequence:

>915_bases
ATGGATCTGCGGCAGATGCGCTATTTCCTGGCCGTGGTCGACGCCGGGTCGTTTTCCGCCGCCGCCCGCGCCCTGCGCGT
CGCCCAGCCGGCGCTGTCGCAAAGCCTGAAGCGGCTGGAAGACGAGGTCGGCGCCGCCCTGCTTCACCGCCTGCCGCGCG
GCACCCTGCCCACCGAGGAGGGCCTGCTTCTGGCGGCCGAGGGGCGGCGGTTGCTTGCCGAGTGGGATGGCCTGGGCGGC
CTGTTGCGCGCCCGGCGTGACGATCCAGCCGGCGATCTGGCGATCGGCATCCCAACCTCGCTGGGGCCGGTGGTCAGTCT
GGCCGTCGCCCGGCTGGTCGCCCGGCGATTGCCCAAGGTGCGGTTGCGGCTGATCGAGGGGCTGTCGGGCCATATCATGG
GCTGGCTGCGCGACGGCACGCTCGATCTGGGGCTGGTGTTCAATGGCGAGACCGGCGGCGACCTTGGCGTCGAGCCTTTG
GCCAGCGAATGTCTGGCGCTGATCGCCCCGGCGGCCAGTTCGCTGCCCACGCCGATCCCCCTCAACGCGGCGGCGGCGTT
GCCGCTGATCCTGCCCGGCCCGCCGCACGGTCTGCGCGACGAGGTGGAGCGCGCCTTCGCCAGTCGCGGGCTGGTCGCCA
AGGTTTGCCTGGAGATCGACGCCCTTGATCCGATCAACACCCTGGTCGCCGAGGGCTTTGGCTATTCCATCTTGTCGCCG
CGCGTCGCCCTGCAATCGACGGGGGCGGCGCTGGTGCGGGTGATCCCGATCATCGATCCGCCGATCACCCGCAGGATCGG
CCTGGCCCAGGCCCGCCTGCGCCCGCCCAGCATCGCCCTGCGCCACGCCCTGCCGTTGCTGCGGCCGCTGATCGGCCGGC
TGGTGCGCGACGGCGCCGGGGTCGGGCTAGAATAA

Upstream 100 bases:

>100_bases
TGACGCCAGTGTGGGCGGGTGCTTGCCATAGGTCAAAAACAGAGTTTTTATGGGATCGATCATTTTTTGATATGGCAAGT
AAGCAAGGGCGGCCCGGGCC

Downstream 100 bases:

>100_bases
TGATCTAGAGAAGTATTCTAGAGCGAATTTTCAGAGATAAGGCGGTGGCGCTGCGGGCCGTGCTTTGTTTCCGCCGCGCC
TTAGGGTAAAACTCGCCCCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen assimilation control protein [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MDLRQMRYFLAVVDAGSFSAAARALRVAQPALSQSLKRLEDEVGAALLHRLPRGTLPTEEGLLLAAEGRRLLAEWDGLGG
LLRARRDDPAGDLAIGIPTSLGPVVSLAVARLVARRLPKVRLRLIEGLSGHIMGWLRDGTLDLGLVFNGETGGDLGVEPL
ASECLALIAPAASSLPTPIPLNAAAALPLILPGPPHGLRDEVERAFASRGLVAKVCLEIDALDPINTLVAEGFGYSILSP
RVALQSTGAALVRVIPIIDPPITRRIGLAQARLRPPSIALRHALPLLRPLIGRLVRDGAGVGLE

Sequences:

>Translated_304_residues
MDLRQMRYFLAVVDAGSFSAAARALRVAQPALSQSLKRLEDEVGAALLHRLPRGTLPTEEGLLLAAEGRRLLAEWDGLGG
LLRARRDDPAGDLAIGIPTSLGPVVSLAVARLVARRLPKVRLRLIEGLSGHIMGWLRDGTLDLGLVFNGETGGDLGVEPL
ASECLALIAPAASSLPTPIPLNAAAALPLILPGPPHGLRDEVERAFASRGLVAKVCLEIDALDPINTLVAEGFGYSILSP
RVALQSTGAALVRVIPIIDPPITRRIGLAQARLRPPSIALRHALPLLRPLIGRLVRDGAGVGLE
>Mature_304_residues
MDLRQMRYFLAVVDAGSFSAAARALRVAQPALSQSLKRLEDEVGAALLHRLPRGTLPTEEGLLLAAEGRRLLAEWDGLGG
LLRARRDDPAGDLAIGIPTSLGPVVSLAVARLVARRLPKVRLRLIEGLSGHIMGWLRDGTLDLGLVFNGETGGDLGVEPL
ASECLALIAPAASSLPTPIPLNAAAALPLILPGPPHGLRDEVERAFASRGLVAKVCLEIDALDPINTLVAEGFGYSILSP
RVALQSTGAALVRVIPIIDPPITRRIGLAQARLRPPSIALRHALPLLRPLIGRLVRDGAGVGLE

Specific function: Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation. Negative regulator of its own expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788297, Length=251, Percent_Identity=28.6852589641434, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1790399, Length=273, Percent_Identity=27.4725274725275, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI157672245, Length=263, Percent_Identity=29.277566539924, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787879, Length=292, Percent_Identity=29.7945205479452, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI145693105, Length=270, Percent_Identity=24.0740740740741, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787601, Length=203, Percent_Identity=27.0935960591133, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788748, Length=287, Percent_Identity=27.8745644599303, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788481, Length=290, Percent_Identity=26.2068965517241, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789639, Length=126, Percent_Identity=32.5396825396825, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789506, Length=223, Percent_Identity=23.3183856502242, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789204, Length=270, Percent_Identity=27.037037037037, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI2367136, Length=269, Percent_Identity=26.0223048327138, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788296, Length=259, Percent_Identity=25.8687258687259, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32044; Mature: 32044

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLRQMRYFLAVVDAGSFSAAARALRVAQPALSQSLKRLEDEVGAALLHRLPRGTLPTEE
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GLLLAAEGRRLLAEWDGLGGLLRARRDDPAGDLAIGIPTSLGPVVSLAVARLVARRLPKV
CEEEECCCCCHHHHHCCHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCHHH
RLRLIEGLSGHIMGWLRDGTLDLGLVFNGETGGDLGVEPLASECLALIAPAASSLPTPIP
HHHHHHCCCCHHEEEEECCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
LNAAAALPLILPGPPHGLRDEVERAFASRGLVAKVCLEIDALDPINTLVAEGFGYSILSP
CCCHHHCCEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHCCCCCHHHCC
RVALQSTGAALVRVIPIIDPPITRRIGLAQARLRPPSIALRHALPLLRPLIGRLVRDGAG
HHHHHHCCHHHHHEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
VGLE
CCCC
>Mature Secondary Structure
MDLRQMRYFLAVVDAGSFSAAARALRVAQPALSQSLKRLEDEVGAALLHRLPRGTLPTEE
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GLLLAAEGRRLLAEWDGLGGLLRARRDDPAGDLAIGIPTSLGPVVSLAVARLVARRLPKV
CEEEECCCCCHHHHHCCHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCHHH
RLRLIEGLSGHIMGWLRDGTLDLGLVFNGETGGDLGVEPLASECLALIAPAASSLPTPIP
HHHHHHCCCCHHEEEEECCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
LNAAAALPLILPGPPHGLRDEVERAFASRGLVAKVCLEIDALDPINTLVAEGFGYSILSP
CCCHHHCCEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHCCCCCHHHCC
RVALQSTGAALVRVIPIIDPPITRRIGLAQARLRPPSIALRHALPLLRPLIGRLVRDGAG
HHHHHHCCHHHHHEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
VGLE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8458853 [H]