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The map label for this gene is arsC [H]

Identifier: 83593327

GI number: 83593327

Start: 2303016

End: 2303435

Strand: Reverse

Name: arsC [H]

Synonym: Rru_A1992

Alternate gene names: 83593327

Gene position: 2303435-2303016 (Counterclockwise)

Preceding gene: 83593328

Following gene: 83593326

Centisome position: 52.92

GC content: 65.48

Gene sequence:

>420_bases
ATGGGCGTCACCATTTATCATAATCCGGCCTGCGGAACCTCGCGCAACGTGCTGGCGATGATCCGTCAGAGCGGCGAAGA
GCCCCGGGTGATCGACTATCTGAAAACGCCGCTGTCGCGGGCCGAATTGGTCGATCTGATCGCCGTTCTGGCGATCCCCG
TGCGCGATTTGCTGCGGCGCAAGGGCACGCCCTTTGACGCCCTCGGGCTTGAGGATCCGGCGCTGTCCGACGACGCCCTG
ATCGACGCCATGGTCGCCCATCCCATCCTGATCAATCGGCCGATCGTCGTCACCGCCAAGGGCGCGGCCTTGTGCCGGCC
TTCGGAAGCGGTTCTGGCCATCCTGCCCACTCCCTTGGTCGGGTCCTTCACCAAGGAGGACGGCGAGGTCGTTTCCGCCC
CCGCCCCGTCCACCCCTTGA

Upstream 100 bases:

>100_bases
GGTAACCCGCCTATCGCTCGATCGCGATGATCTGGGCCCGCTGTGGTGCGGCGACCTGCTGGTTTTCGATATCTGACGAT
TTGGCGGCGAGGGCAAGGCG

Downstream 100 bases:

>100_bases
GCTTTCGCCGCCTTCGGGAACCTTTTGCCCGGCTTTGGCGTCACCCTTGGCCAATCACGGCGAGGGGGGCGCGGGCATGG
TCAAGGGGGACGGCGACGGG

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 139; Mature: 138

Protein sequence:

>139_residues
MGVTIYHNPACGTSRNVLAMIRQSGEEPRVIDYLKTPLSRAELVDLIAVLAIPVRDLLRRKGTPFDALGLEDPALSDDAL
IDAMVAHPILINRPIVVTAKGAALCRPSEAVLAILPTPLVGSFTKEDGEVVSAPAPSTP

Sequences:

>Translated_139_residues
MGVTIYHNPACGTSRNVLAMIRQSGEEPRVIDYLKTPLSRAELVDLIAVLAIPVRDLLRRKGTPFDALGLEDPALSDDAL
IDAMVAHPILINRPIVVTAKGAALCRPSEAVLAILPTPLVGSFTKEDGEVVSAPAPSTP
>Mature_138_residues
GVTIYHNPACGTSRNVLAMIRQSGEEPRVIDYLKTPLSRAELVDLIAVLAIPVRDLLRRKGTPFDALGLEDPALSDDALI
DAMVAHPILINRPIVVTAKGAALCRPSEAVLAILPTPLVGSFTKEDGEVVSAPAPSTP

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=130, Percent_Identity=62.3076923076923, Blast_Score=164, Evalue=3e-42,
Organism=Escherichia coli, GI1788841, Length=114, Percent_Identity=45.6140350877193, Blast_Score=100, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 14715; Mature: 14584

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVTIYHNPACGTSRNVLAMIRQSGEEPRVIDYLKTPLSRAELVDLIAVLAIPVRDLLRR
CCEEEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
KGTPFDALGLEDPALSDDALIDAMVAHPILINRPIVVTAKGAALCRPSEAVLAILPTPLV
CCCCCCCCCCCCCCCCCHHHHHHHHHCCEEECCCEEEEECCCEEECCCCCEEEEECCCCC
GSFTKEDGEVVSAPAPSTP
CCCCCCCCCEEECCCCCCC
>Mature Secondary Structure 
GVTIYHNPACGTSRNVLAMIRQSGEEPRVIDYLKTPLSRAELVDLIAVLAIPVRDLLRR
CEEEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
KGTPFDALGLEDPALSDDALIDAMVAHPILINRPIVVTAKGAALCRPSEAVLAILPTPLV
CCCCCCCCCCCCCCCCCHHHHHHHHHCCEEECCCEEEEECCCEEECCCCCEEEEECCCCC
GSFTKEDGEVVSAPAPSTP
CCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9006011 [H]