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The map label for this gene is trpD

Identifier: 83593231

GI number: 83593231

Start: 2197727

End: 2198770

Strand: Direct

Name: trpD

Synonym: Rru_A1896

Alternate gene names: 83593231

Gene position: 2197727-2198770 (Clockwise)

Preceding gene: 83593230

Following gene: 83593232

Centisome position: 50.49

GC content: 70.02

Gene sequence:

>1044_bases
ATGACGACACAGCCGACCACAGCAAACGATATCAAGGGCCTGATCGCCATGGTCGCCACCGGGCGGCCGCTTTCCGAGGC
CGATGCCACCCGGGCTTTCGAAGCGATCATGTCGGGCAACGCCACGCCAGCCCAGATCGGCGGCTTTCTGATGGCGCTGC
GCGTGCGCGGCGAAACCGTGGCCGAGATCACGGCGGCGGCGCGCACCATGCGCGACAAGGCCGCCCGCATCCAGGCCCCC
GCCGGCGCCATCGACATCGTCGGCACCGGCGGCGATTGCGCCGGCACCTATAACATCTCGACCGCCGCCGCCCTGGTGAC
GGCGGCCTGCGGCGTGCCGGTGGCCAAACATGGCAATCGCGCCGCCTCGTCGAAAAGCGGATCGGCCGATGTGCTGGCCG
CGCTGGGCGTCAACCTCGATGCCGATCTTGCCCTGGTCGAACGCTCGATCGCCGAGGTCGGCATCGGCTTCATGTTCGCC
CAGCGCCACCATAGCGCCATGAAACATGTCGCCCCCGCCCGCTCGGAACTGGGAACGCGCACGATCTTCAACCTGCTGGG
GCCTTTGGCCAATCCGGCCGGCGCCCGCTTCGAATTGATGGGGGTTTTCGCCCAGGAATGGGTGGAGCCGTTGGCCGAGG
TGCTGGGCCGACTGGGCGCCGAGCGCGCCTGGGTGGTCCATGGCTCCGACGGCCTGGATGAGATCACCACCACCGGCCCC
ACCCATGTCGCCGAATTCCGCGGCGGCGTCGTGCGCTCGTTCGACATCACCCCCGCCGACGCCGGCCTGCCGCTGGCCAA
GGCCGAAGACCTGCAGGGCGCCGATCCCGAGGCCAATGCCCAGGCCCTGCGCGCCCTTCTCGAGGGCGTGAAAACCCCCT
ATCGCGACATCGTCGTTTTCAACGCCGCCGCCGCCCTGGTGGTAGCCGGCGCGGCCGAGGATCTGGCGACCGGGGCGGCG
CGGGCCGCCCAGGCCATCGACAGCGGCGCGGCGAAGGACACCCTGGCGCGCATGATCGCCATCATCGGAGCCCCGGCATC
GTGA

Upstream 100 bases:

>100_bases
AGGGGGTGCAGTTCCATCCCGAAAGCATTGAAACCCAAGGCGGTCACCACCTGCTGCGGAATTTTCTGACCTTAGCCCGC
CAGGGGGGAGACGCGGTCTG

Downstream 100 bases:

>100_bases
GCGACATTCTGCGCGAGATCTGCGACACCACCCGCGCCGAGGTGGCGCGGCGCAAGGCCGCCCTGCCCTTAGCCGATGTG
ACGGCGCGGGCGGAAGACGC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MTTQPTTANDIKGLIAMVATGRPLSEADATRAFEAIMSGNATPAQIGGFLMALRVRGETVAEITAAARTMRDKAARIQAP
AGAIDIVGTGGDCAGTYNISTAAALVTAACGVPVAKHGNRAASSKSGSADVLAALGVNLDADLALVERSIAEVGIGFMFA
QRHHSAMKHVAPARSELGTRTIFNLLGPLANPAGARFELMGVFAQEWVEPLAEVLGRLGAERAWVVHGSDGLDEITTTGP
THVAEFRGGVVRSFDITPADAGLPLAKAEDLQGADPEANAQALRALLEGVKTPYRDIVVFNAAAALVVAGAAEDLATGAA
RAAQAIDSGAAKDTLARMIAIIGAPAS

Sequences:

>Translated_347_residues
MTTQPTTANDIKGLIAMVATGRPLSEADATRAFEAIMSGNATPAQIGGFLMALRVRGETVAEITAAARTMRDKAARIQAP
AGAIDIVGTGGDCAGTYNISTAAALVTAACGVPVAKHGNRAASSKSGSADVLAALGVNLDADLALVERSIAEVGIGFMFA
QRHHSAMKHVAPARSELGTRTIFNLLGPLANPAGARFELMGVFAQEWVEPLAEVLGRLGAERAWVVHGSDGLDEITTTGP
THVAEFRGGVVRSFDITPADAGLPLAKAEDLQGADPEANAQALRALLEGVKTPYRDIVVFNAAAALVVAGAAEDLATGAA
RAAQAIDSGAAKDTLARMIAIIGAPAS
>Mature_346_residues
TTQPTTANDIKGLIAMVATGRPLSEADATRAFEAIMSGNATPAQIGGFLMALRVRGETVAEITAAARTMRDKAARIQAPA
GAIDIVGTGGDCAGTYNISTAAALVTAACGVPVAKHGNRAASSKSGSADVLAALGVNLDADLALVERSIAEVGIGFMFAQ
RHHSAMKHVAPARSELGTRTIFNLLGPLANPAGARFELMGVFAQEWVEPLAEVLGRLGAERAWVVHGSDGLDEITTTGPT
HVAEFRGGVVRSFDITPADAGLPLAKAEDLQGADPEANAQALRALLEGVKTPYRDIVVFNAAAALVVAGAAEDLATGAAR
AAQAIDSGAAKDTLARMIAIIGAPAS

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=327, Percent_Identity=40.9785932721713, Blast_Score=228, Evalue=6e-61,
Organism=Escherichia coli, GI1787019, Length=331, Percent_Identity=24.4712990936556, Blast_Score=65, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6320561, Length=327, Percent_Identity=29.3577981651376, Blast_Score=125, Evalue=9e-30,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_RHORT (Q2RT49)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_426983.1
- HSSP:   P50384
- ProteinModelPortal:   Q2RT49
- SMR:   Q2RT49
- STRING:   Q2RT49
- GeneID:   3835320
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A1896
- NMPDR:   fig|1085.1.peg.2469
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   ATPSQMG
- PhylomeDB:   Q2RT49
- ProtClustDB:   PRK00188
- BioCyc:   RRUB269796:RRU_A1896-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 35308; Mature: 35176

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQPTTANDIKGLIAMVATGRPLSEADATRAFEAIMSGNATPAQIGGFLMALRVRGETV
CCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHH
AEITAAARTMRDKAARIQAPAGAIDIVGTGGDCAGTYNISTAAALVTAACGVPVAKHGNR
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHCCCC
AASSKSGSADVLAALGVNLDADLALVERSIAEVGIGFMFAQRHHSAMKHVAPARSELGTR
CCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIFNLLGPLANPAGARFELMGVFAQEWVEPLAEVLGRLGAERAWVVHGSDGLDEITTTGP
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCCC
THVAEFRGGVVRSFDITPADAGLPLAKAEDLQGADPEANAQALRALLEGVKTPYRDIVVF
HHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHEEEE
NAAAALVVAGAAEDLATGAARAAQAIDSGAAKDTLARMIAIIGAPAS
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TTQPTTANDIKGLIAMVATGRPLSEADATRAFEAIMSGNATPAQIGGFLMALRVRGETV
CCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHH
AEITAAARTMRDKAARIQAPAGAIDIVGTGGDCAGTYNISTAAALVTAACGVPVAKHGNR
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHCCCC
AASSKSGSADVLAALGVNLDADLALVERSIAEVGIGFMFAQRHHSAMKHVAPARSELGTR
CCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIFNLLGPLANPAGARFELMGVFAQEWVEPLAEVLGRLGAERAWVVHGSDGLDEITTTGP
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCCC
THVAEFRGGVVRSFDITPADAGLPLAKAEDLQGADPEANAQALRALLEGVKTPYRDIVVF
HHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHEEEE
NAAAALVVAGAAEDLATGAARAAQAIDSGAAKDTLARMIAIIGAPAS
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA