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The map label for this gene is acdA [H]

Identifier: 83593170

GI number: 83593170

Start: 2131939

End: 2133078

Strand: Reverse

Name: acdA [H]

Synonym: Rru_A1835

Alternate gene names: 83593170

Gene position: 2133078-2131939 (Counterclockwise)

Preceding gene: 83593173

Following gene: 83593169

Centisome position: 49.0

GC content: 66.84

Gene sequence:

>1140_bases
ATGGATTTTCAACCCACGGCGGACCAAAAGCAGTTCCAGGAGTTGGCGCGCGGCTTTGCCGATGCCGAGATGAAACCCCG
GGCCCGCGCCTGGGACGAGGGGGCGATCTTTCCGGTTGAAACCCTGCGGGCCGCCGCCGCCCTGGGCTTCGCCGGCATCT
ATGTGGGCGAGGAGTTCGGCGGGGCCGGGCTGACCCGCCTGGACGCCGCCCTGATCTTTGAAGAACTGGCGACCGCCTGC
CCGTCGACCGCCGCCTTCTTGACCATCCACAATATGGCGAGTTCGATGATCGACCGCTTCGCCGGCCGGGATCTGCGGGC
CCGCCTGCTACCCGGGCTGATGACGATGGAGCGCTTCGCCAGCTATTGCCTGACCGAACCGGGGGCGGGGTCCGATGCCG
CTGCCTTGCGCACCCGGGCGGTGCGCGATGGCGACGGCTATCGGCTAAGCGGCCAGAAGGCCTTCATCTCGGGCGGCGGC
CATAGCGATGTTTATGTGGTGATGGCGCGCACCGGCGAGGCCGGGGCCAAGGGGATCTCGGCCTTCGTCGTCGAGGCCGG
CGCGCCGGGGCTGTCCTTTGGCAAGCCCGAGGCCAAGATGGGCTGGAAAAGCCAGCCGACCTGCGCGGTGATGTTCGATG
ATCTGCGCGTTCCCGCCAGCCATCGCCTGGGCGAGGAGGGCGAGGGCTTTCGCATCGCCATGATGGGGCTGGACGGCGGC
CGGCTGAATATCGGCGCCTGTTCGCTGGGCGGAGCCAAGGGGGCTTTCGAAGCGGCGCTGGCCTATGTCAAGGAACGCCG
GCAATTCGGCAAGGCCATCGCCGAGTTCCAGGCCACCCAGTTCACCCTGGCCGATATGGCGACCGCCCTGGAAGCGGCCC
GGCTGCTGCTCCACAAGGCCGCCTGGCTGCTCGATGCCGGCGATCCAAGCGCCACCAGCTTTTGCGCCATGGCCAAACGA
CTGGCGACCGACACCGGATTTAGCGTGTGTGATCAAGCGCTTCAGCTTCACGGCGGCTACGGGTACACCAGTGACTATCC
GGTCGAACGGCTGTTGCGCGATCTGCGCGTTCACCGGATCTTGGAAGGCACCAACGAGATCATGCGGGTGATCATCGGCC
GCCGACTGCTGGCCGATTAG

Upstream 100 bases:

>100_bases
TCCCATTACCCGACCAATCGGTATACTTCCCTTAAAAAAGAGCCAAGACCAAACGGTCCGGGCGCCAAGCGGATCCGGCT
TCACAACGGGAGGGGTGTCG

Downstream 100 bases:

>100_bases
CAGATCCCCCGCTTCCCCTGCGTCAAGGACCCGTGATGAGCGACGACGACATCCTGTTTGAGCAAAAGGGCGCCTTGGGC
GCCATCACCCTTAACCGGCC

Product: butyryl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MDFQPTADQKQFQELARGFADAEMKPRARAWDEGAIFPVETLRAAAALGFAGIYVGEEFGGAGLTRLDAALIFEELATAC
PSTAAFLTIHNMASSMIDRFAGRDLRARLLPGLMTMERFASYCLTEPGAGSDAAALRTRAVRDGDGYRLSGQKAFISGGG
HSDVYVVMARTGEAGAKGISAFVVEAGAPGLSFGKPEAKMGWKSQPTCAVMFDDLRVPASHRLGEEGEGFRIAMMGLDGG
RLNIGACSLGGAKGAFEAALAYVKERRQFGKAIAEFQATQFTLADMATALEAARLLLHKAAWLLDAGDPSATSFCAMAKR
LATDTGFSVCDQALQLHGGYGYTSDYPVERLLRDLRVHRILEGTNEIMRVIIGRRLLAD

Sequences:

>Translated_379_residues
MDFQPTADQKQFQELARGFADAEMKPRARAWDEGAIFPVETLRAAAALGFAGIYVGEEFGGAGLTRLDAALIFEELATAC
PSTAAFLTIHNMASSMIDRFAGRDLRARLLPGLMTMERFASYCLTEPGAGSDAAALRTRAVRDGDGYRLSGQKAFISGGG
HSDVYVVMARTGEAGAKGISAFVVEAGAPGLSFGKPEAKMGWKSQPTCAVMFDDLRVPASHRLGEEGEGFRIAMMGLDGG
RLNIGACSLGGAKGAFEAALAYVKERRQFGKAIAEFQATQFTLADMATALEAARLLLHKAAWLLDAGDPSATSFCAMAKR
LATDTGFSVCDQALQLHGGYGYTSDYPVERLLRDLRVHRILEGTNEIMRVIIGRRLLAD
>Mature_379_residues
MDFQPTADQKQFQELARGFADAEMKPRARAWDEGAIFPVETLRAAAALGFAGIYVGEEFGGAGLTRLDAALIFEELATAC
PSTAAFLTIHNMASSMIDRFAGRDLRARLLPGLMTMERFASYCLTEPGAGSDAAALRTRAVRDGDGYRLSGQKAFISGGG
HSDVYVVMARTGEAGAKGISAFVVEAGAPGLSFGKPEAKMGWKSQPTCAVMFDDLRVPASHRLGEEGEGFRIAMMGLDGG
RLNIGACSLGGAKGAFEAALAYVKERRQFGKAIAEFQATQFTLADMATALEAARLLLHKAAWLLDAGDPSATSFCAMAKR
LATDTGFSVCDQALQLHGGYGYTSDYPVERLLRDLRVHRILEGTNEIMRVIIGRRLLAD

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7656849, Length=372, Percent_Identity=55.3763440860215, Blast_Score=434, Evalue=1e-122,
Organism=Homo sapiens, GI4501859, Length=376, Percent_Identity=38.031914893617, Blast_Score=263, Evalue=2e-70,
Organism=Homo sapiens, GI187960098, Length=377, Percent_Identity=37.9310344827586, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI4557231, Length=377, Percent_Identity=37.9310344827586, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI4557233, Length=375, Percent_Identity=38.9333333333333, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI4501857, Length=380, Percent_Identity=34.7368421052632, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI21361497, Length=380, Percent_Identity=34.2105263157895, Blast_Score=218, Evalue=9e-57,
Organism=Homo sapiens, GI226958412, Length=380, Percent_Identity=32.1052631578947, Blast_Score=208, Evalue=7e-54,
Organism=Homo sapiens, GI226958414, Length=344, Percent_Identity=33.4302325581395, Blast_Score=199, Evalue=3e-51,
Organism=Homo sapiens, GI76496475, Length=345, Percent_Identity=36.5217391304348, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI4557235, Length=345, Percent_Identity=36.5217391304348, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI4503943, Length=380, Percent_Identity=26.8421052631579, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI38505218, Length=338, Percent_Identity=27.2189349112426, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI7669494, Length=356, Percent_Identity=26.4044943820225, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI211971008, Length=387, Percent_Identity=28.1653746770026, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI48976061, Length=387, Percent_Identity=28.1653746770026, Blast_Score=105, Evalue=8e-23,
Organism=Escherichia coli, GI87081958, Length=383, Percent_Identity=33.9425587467363, Blast_Score=177, Evalue=8e-46,
Organism=Escherichia coli, GI1786223, Length=379, Percent_Identity=29.8153034300792, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI87082384, Length=287, Percent_Identity=31.7073170731707, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17533517, Length=373, Percent_Identity=49.3297587131367, Blast_Score=384, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17570075, Length=382, Percent_Identity=37.434554973822, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI17534899, Length=383, Percent_Identity=37.0757180156658, Blast_Score=262, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI17569725, Length=381, Percent_Identity=37.2703412073491, Blast_Score=261, Evalue=6e-70,
Organism=Caenorhabditis elegans, GI17506239, Length=373, Percent_Identity=36.9973190348526, Blast_Score=246, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI17508101, Length=361, Percent_Identity=36.01108033241, Blast_Score=239, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI71985184, Length=349, Percent_Identity=36.3896848137536, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17538396, Length=368, Percent_Identity=35.054347826087, Blast_Score=204, Evalue=7e-53,
Organism=Caenorhabditis elegans, GI71990804, Length=277, Percent_Identity=40.072202166065, Blast_Score=195, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI32563615, Length=229, Percent_Identity=41.4847161572052, Blast_Score=181, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI71985192, Length=284, Percent_Identity=35.2112676056338, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17505929, Length=359, Percent_Identity=30.6406685236769, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI71982178, Length=273, Percent_Identity=29.6703296703297, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17551932, Length=357, Percent_Identity=29.9719887955182, Blast_Score=147, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI17534353, Length=375, Percent_Identity=27.2, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17562446, Length=346, Percent_Identity=26.5895953757225, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17531909, Length=240, Percent_Identity=28.3333333333333, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI86563383, Length=307, Percent_Identity=28.6644951140065, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI86563381, Length=307, Percent_Identity=28.6644951140065, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24660351, Length=378, Percent_Identity=36.7724867724868, Blast_Score=253, Evalue=1e-67,
Organism=Drosophila melanogaster, GI24646207, Length=367, Percent_Identity=39.2370572207085, Blast_Score=252, Evalue=3e-67,
Organism=Drosophila melanogaster, GI21356377, Length=373, Percent_Identity=36.9973190348526, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI24666513, Length=376, Percent_Identity=36.1702127659575, Blast_Score=242, Evalue=3e-64,
Organism=Drosophila melanogaster, GI21355753, Length=375, Percent_Identity=35.7333333333333, Blast_Score=218, Evalue=5e-57,
Organism=Drosophila melanogaster, GI281363737, Length=385, Percent_Identity=34.2857142857143, Blast_Score=203, Evalue=1e-52,
Organism=Drosophila melanogaster, GI19920834, Length=380, Percent_Identity=26.8421052631579, Blast_Score=127, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 40527; Mature: 40527

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFQPTADQKQFQELARGFADAEMKPRARAWDEGAIFPVETLRAAAALGFAGIYVGEEFG
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCC
GAGLTRLDAALIFEELATACPSTAAFLTIHNMASSMIDRFAGRDLRARLLPGLMTMERFA
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SYCLTEPGAGSDAAALRTRAVRDGDGYRLSGQKAFISGGGHSDVYVVMARTGEAGAKGIS
HHHCCCCCCCCCHHHHHHHHHCCCCCEEECCCEEEEECCCCCCEEEEEEECCCCCCCCCE
AFVVEAGAPGLSFGKPEAKMGWKSQPTCAVMFDDLRVPASHRLGEEGEGFRIAMMGLDGG
EEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHCCCCCCCCEEEEEEECCCC
RLNIGACSLGGAKGAFEAALAYVKERRQFGKAIAEFQATQFTLADMATALEAARLLLHKA
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWLLDAGDPSATSFCAMAKRLATDTGFSVCDQALQLHGGYGYTSDYPVERLLRDLRVHRI
HHHEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
LEGTNEIMRVIIGRRLLAD
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDFQPTADQKQFQELARGFADAEMKPRARAWDEGAIFPVETLRAAAALGFAGIYVGEEFG
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCC
GAGLTRLDAALIFEELATACPSTAAFLTIHNMASSMIDRFAGRDLRARLLPGLMTMERFA
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SYCLTEPGAGSDAAALRTRAVRDGDGYRLSGQKAFISGGGHSDVYVVMARTGEAGAKGIS
HHHCCCCCCCCCHHHHHHHHHCCCCCEEECCCEEEEECCCCCCEEEEEEECCCCCCCCCE
AFVVEAGAPGLSFGKPEAKMGWKSQPTCAVMFDDLRVPASHRLGEEGEGFRIAMMGLDGG
EEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHCCCCCCCCEEEEEEECCCC
RLNIGACSLGGAKGAFEAALAYVKERRQFGKAIAEFQATQFTLADMATALEAARLLLHKA
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWLLDAGDPSATSFCAMAKRLATDTGFSVCDQALQLHGGYGYTSDYPVERLLRDLRVHRI
HHHEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
LEGTNEIMRVIIGRRLLAD
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]