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The map label for this gene is coaD

Identifier: 83593078

GI number: 83593078

Start: 2033852

End: 2034370

Strand: Reverse

Name: coaD

Synonym: Rru_A1743

Alternate gene names: 83593078

Gene position: 2034370-2033852 (Counterclockwise)

Preceding gene: 83593079

Following gene: 83593077

Centisome position: 46.74

GC content: 60.5

Gene sequence:

>519_bases
ATGATGCCGACTGAACGCATCGCGGTTTATCCGGGGACCTTCGACCCGGTCACCAACGGTCATCTCGACATCATCAGCCG
GGCGGCGCGGCTGGTTGATCGTCTGACCGTTGGCGTCGCCGTCAATGCCGGCAAGGGCCCGCTGTTTTCGCTCGAGGAAC
GGGTGGAGATGGTGCGGGTGGCGGTTGACAAGCTGCCGACCAACGGGGCGACGATCACCGTCGTCCCGTTTGCCAATCTG
CTGATGGATTTCGCCTGTGCCCAGGGAGCCTCGATGATCTTTCGCGGGCTGCGGGCGATTTCCGATTTTGAATACGAATT
TCAGATGTGCGGCATGAATTCCCGCCTTAATTCCAAGGTGGAGACGGTTTTTTTGATGGCCTCGGAACGCAGCCAGTTCA
TCTCGTCGCGCTTCGTCAAGGAAATCGGCCGTCTTGGCGGGGATATCGGCGGCTTCGTCCCCGCCCATGTCCGCGATCGC
TTGCTCGACCGCTTCGAGGAAGACGCCGAATCCGCCTGA

Upstream 100 bases:

>100_bases
CCTGACGAGTCCTTGGCCGAGGATGCCAACGGGGGGAGGGACGAGAGCGGGGAAGCGTCCGGCCTCCCGCCCGCGGGCCA
ATCCCCCGAACGGAACGGGG

Downstream 100 bases:

>100_bases
GCCAAGCCCCCTCCCTCCCTCAAGAGGTCAAGGAAACGCCATATGCGCCGCATCCTGATCAGTTTATTCGCTCTACTCGC
CTGCATGGGAACTGTCATGA

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MMPTERIAVYPGTFDPVTNGHLDIISRAARLVDRLTVGVAVNAGKGPLFSLEERVEMVRVAVDKLPTNGATITVVPFANL
LMDFACAQGASMIFRGLRAISDFEYEFQMCGMNSRLNSKVETVFLMASERSQFISSRFVKEIGRLGGDIGGFVPAHVRDR
LLDRFEEDAESA

Sequences:

>Translated_172_residues
MMPTERIAVYPGTFDPVTNGHLDIISRAARLVDRLTVGVAVNAGKGPLFSLEERVEMVRVAVDKLPTNGATITVVPFANL
LMDFACAQGASMIFRGLRAISDFEYEFQMCGMNSRLNSKVETVFLMASERSQFISSRFVKEIGRLGGDIGGFVPAHVRDR
LLDRFEEDAESA
>Mature_172_residues
MMPTERIAVYPGTFDPVTNGHLDIISRAARLVDRLTVGVAVNAGKGPLFSLEERVEMVRVAVDKLPTNGATITVVPFANL
LMDFACAQGASMIFRGLRAISDFEYEFQMCGMNSRLNSKVETVFLMASERSQFISSRFVKEIGRLGGDIGGFVPAHVRDR
LLDRFEEDAESA

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=161, Percent_Identity=43.4782608695652, Blast_Score=155, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_RHORT (Q2RTK2)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_426830.1
- HSSP:   Q9WZK0
- ProteinModelPortal:   Q2RTK2
- SMR:   Q2RTK2
- STRING:   Q2RTK2
- GeneID:   3835165
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A1743
- NMPDR:   fig|1085.1.peg.2318
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- PhylomeDB:   Q2RTK2
- ProtClustDB:   PRK00168
- BioCyc:   RRUB269796:RRU_A1743-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18936; Mature: 18936

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPTERIAVYPGTFDPVTNGHLDIISRAARLVDRLTVGVAVNAGKGPLFSLEERVEMVRV
CCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHH
AVDKLPTNGATITVVPFANLLMDFACAQGASMIFRGLRAISDFEYEFQMCGMNSRLNSKV
HHHHCCCCCCEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHEECCCCCCCCCHH
ETVFLMASERSQFISSRFVKEIGRLGGDIGGFVPAHVRDRLLDRFEEDAESA
HHHEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMPTERIAVYPGTFDPVTNGHLDIISRAARLVDRLTVGVAVNAGKGPLFSLEERVEMVRV
CCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHH
AVDKLPTNGATITVVPFANLLMDFACAQGASMIFRGLRAISDFEYEFQMCGMNSRLNSKV
HHHHCCCCCCEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHEECCCCCCCCCHH
ETVFLMASERSQFISSRFVKEIGRLGGDIGGFVPAHVRDRLLDRFEEDAESA
HHHEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA