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The map label for this gene is bigR [H]

Identifier: 83593052

GI number: 83593052

Start: 2008544

End: 2008912

Strand: Reverse

Name: bigR [H]

Synonym: Rru_A1717

Alternate gene names: 83593052

Gene position: 2008912-2008544 (Counterclockwise)

Preceding gene: 83593058

Following gene: 83593051

Centisome position: 46.15

GC content: 68.29

Gene sequence:

>369_bases
ATGCCAGCCGTTGTGAACGATAACGCCCGGGTCGATGACCCCGATGCCGATCCGGCGCGCATGGCGCGCGCCGAGATGGA
GAGGCGAGCCGCCGAGGTGGCGGGCCTGCTTAAAACCCTGTCCCACCCCTTGCGCCTGATGCTGGTCTGCGCCCTGGTCG
AGGGGGAATATGGCGTGGGCGCCCTGGAAGAGCGGCTCGGCATCGGCCAGCCGGCCCTGTCCCAGCATCTGGGCGTGTTG
CGGGCGGCGGGCCTCGTCGAGACGCGGCGCGAGGCCAAGCAGGTCTTCTATCGCCTGACCGACGCCAAGGCGGCACGGCT
TGTCGAAGCCCTTTACACGATCTTCTGCGTCGAGGAGGGAACGCCATGA

Upstream 100 bases:

>100_bases
CCTCGGGGCGGAAGGGGGCCGGCAAGCCGGTCCTTGACCTCTATCATTATTCATTCTATTTAATTATATAATGTTTGAAT
AAAGAAGGAGGGGGCCGGCG

Downstream 100 bases:

>100_bases
GCGTTTTTTGGCCCCCTTTGCTGGGGGGGATGCTGCTTGGCTTGTCGGCGGCGCTGCTGCTGATCGGCAATGGCAAGGTC
GCCGGAATCAGCGGCATGGC

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 122; Mature: 121

Protein sequence:

>122_residues
MPAVVNDNARVDDPDADPARMARAEMERRAAEVAGLLKTLSHPLRLMLVCALVEGEYGVGALEERLGIGQPALSQHLGVL
RAAGLVETRREAKQVFYRLTDAKAARLVEALYTIFCVEEGTP

Sequences:

>Translated_122_residues
MPAVVNDNARVDDPDADPARMARAEMERRAAEVAGLLKTLSHPLRLMLVCALVEGEYGVGALEERLGIGQPALSQHLGVL
RAAGLVETRREAKQVFYRLTDAKAARLVEALYTIFCVEEGTP
>Mature_121_residues
PAVVNDNARVDDPDADPARMARAEMERRAAEVAGLLKTLSHPLRLMLVCALVEGEYGVGALEERLGIGQPALSQHLGVLR
AAGLVETRREAKQVFYRLTDAKAARLVEALYTIFCVEEGTP

Specific function: Represses an operon that comprises itself, XF_0764, XF_0765, XF_0766 and blh. Binds to a palindromic AT-rich sequence spanning the -10 region of the blh promoter and blocks transcription of the operon [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789021, Length=95, Percent_Identity=31.5789473684211, Blast_Score=63, Evalue=5e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 13272; Mature: 13140

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAVVNDNARVDDPDADPARMARAEMERRAAEVAGLLKTLSHPLRLMLVCALVEGEYGVG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
ALEERLGIGQPALSQHLGVLRAAGLVETRREAKQVFYRLTDAKAARLVEALYTIFCVEEG
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TP
CC
>Mature Secondary Structure 
PAVVNDNARVDDPDADPARMARAEMERRAAEVAGLLKTLSHPLRLMLVCALVEGEYGVG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
ALEERLGIGQPALSQHLGVLRAAGLVETRREAKQVFYRLTDAKAARLVEALYTIFCVEEG
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TP
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]