Click here to switch to the map view.

The map label for this gene is fnr [H]

Identifier: 83592957

GI number: 83592957

Start: 1914994

End: 1915773

Strand: Direct

Name: fnr [H]

Synonym: Rru_A1622

Alternate gene names: 83592957

Gene position: 1914994-1915773 (Clockwise)

Preceding gene: 83592955

Following gene: 83592959

Centisome position: 43.99

GC content: 63.97

Gene sequence:

>780_bases
ATGAGGACGATGGCGGAGAATGAACGATCCGGCTCCACGGCTGAGGATGACGAAGGGGGCGCGGTCGTGAGGGGCAGTCG
GATCGATGCCGCCTGGAAAGGCCTTCCCGAGTGTCGGGCCTGCGGTATTCGCGATCTGGCGCTGTTCGCCGATCTCGAAG
AGGCCGACTTCAAGCTTATCCACCTGCCGATCGAAGAACTGTCCTATGGCGCCGGGGCGGTTCTCTACAACGCCGGCGAT
CCGGCGCGGGCGGTGATGAGCCTGCGTGGCGGCTTGGTCAAGCTGGTGCAATATCTGGGGGATGGCTCGCAGCGCATCGT
GCGGCTGGTGCGGCCGGGCGATTCCATCGGCCTGGAAGCCACCCTTCAGGACAGCTATGAACATACGGCGGTCTTCCTGC
AGCCCGGAATGGTCTGCCGTATCCCGGTCGAGGTGGTGCGCCGCCTCAACGACGAGACCCCCCGGCTGCACCATCAGTTG
ATCACCCGCTGGCACCGCAGTCTGAAACAGGCCGATGACTGGTTGACCGGCCTGTCGACCGGCAACGCCCGCGCCCGGGT
CGCCCGGCTTTTGCTCCATCTCCCCCGCGAGGCCACCGCCGACGGGACGCCGATCTGTGTGCTTTTCAGCCGCGAGGATC
TGGGGGCCATGCTGGGGGTGACCACCGAGACGGCCAGTCGCATCATCGCCGAAATGAAGCGCAGCGGCGTGATAAATGAG
CGCAAATTCAACCAGTTCGCTTGCGATGACGACGCATTACGCAGTTTGTCTGGTGAATAA

Upstream 100 bases:

>100_bases
CACGATCGCCTCTTGGATCAAAACGATCCACCGGAGCGTTTTTCCGTTGGCCCGCCCGAGCGCTATCCGGGCGGGGTCTG
GCGGCGAAGTGTGGGACCCG

Downstream 100 bases:

>100_bases
TCGGGCATTTCGCCTCTTTTTTTTGCACGGCAGGCATGATTTCGCTGCGGGAACGGTCATGCGCTGTGTCAATGCACAGA
CCCCGGTACCCTCCTAAGCT

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MRTMAENERSGSTAEDDEGGAVVRGSRIDAAWKGLPECRACGIRDLALFADLEEADFKLIHLPIEELSYGAGAVLYNAGD
PARAVMSLRGGLVKLVQYLGDGSQRIVRLVRPGDSIGLEATLQDSYEHTAVFLQPGMVCRIPVEVVRRLNDETPRLHHQL
ITRWHRSLKQADDWLTGLSTGNARARVARLLLHLPREATADGTPICVLFSREDLGAMLGVTTETASRIIAEMKRSGVINE
RKFNQFACDDDALRSLSGE

Sequences:

>Translated_259_residues
MRTMAENERSGSTAEDDEGGAVVRGSRIDAAWKGLPECRACGIRDLALFADLEEADFKLIHLPIEELSYGAGAVLYNAGD
PARAVMSLRGGLVKLVQYLGDGSQRIVRLVRPGDSIGLEATLQDSYEHTAVFLQPGMVCRIPVEVVRRLNDETPRLHHQL
ITRWHRSLKQADDWLTGLSTGNARARVARLLLHLPREATADGTPICVLFSREDLGAMLGVTTETASRIIAEMKRSGVINE
RKFNQFACDDDALRSLSGE
>Mature_259_residues
MRTMAENERSGSTAEDDEGGAVVRGSRIDAAWKGLPECRACGIRDLALFADLEEADFKLIHLPIEELSYGAGAVLYNAGD
PARAVMSLRGGLVKLVQYLGDGSQRIVRLVRPGDSIGLEATLQDSYEHTAVFLQPGMVCRIPVEVVRRLNDETPRLHHQL
ITRWHRSLKQADDWLTGLSTGNARARVARLLLHLPREATADGTPICVLFSREDLGAMLGVTTETASRIIAEMKRSGVINE
RKFNQFACDDDALRSLSGE

Specific function: It is involved in the activation of genes necessary for anaerobic respiration [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=225, Percent_Identity=28, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 28452; Mature: 28452

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTMAENERSGSTAEDDEGGAVVRGSRIDAAWKGLPECRACGIRDLALFADLEEADFKLI
CCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHCCCCHHHHCCCHHHHHHHCCCCCCEEEE
HLPIEELSYGAGAVLYNAGDPARAVMSLRGGLVKLVQYLGDGSQRIVRLVRPGDSIGLEA
EECHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEE
TLQDSYEHTAVFLQPGMVCRIPVEVVRRLNDETPRLHHQLITRWHRSLKQADDWLTGLST
EECCCCCCEEEEECCCCEEECHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
GNARARVARLLLHLPREATADGTPICVLFSREDLGAMLGVTTETASRIIAEMKRSGVINE
CCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHCCHHHHHHHHHHHHHHCCCCCC
RKFNQFACDDDALRSLSGE
HHCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MRTMAENERSGSTAEDDEGGAVVRGSRIDAAWKGLPECRACGIRDLALFADLEEADFKLI
CCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHCCCCHHHHCCCHHHHHHHCCCCCCEEEE
HLPIEELSYGAGAVLYNAGDPARAVMSLRGGLVKLVQYLGDGSQRIVRLVRPGDSIGLEA
EECHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEE
TLQDSYEHTAVFLQPGMVCRIPVEVVRRLNDETPRLHHQLITRWHRSLKQADDWLTGLST
EECCCCCCEEEEECCCCEEECHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
GNARARVARLLLHLPREATADGTPICVLFSREDLGAMLGVTTETASRIIAEMKRSGVINE
CCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHCCHHHHHHHHHHHHHHCCCCCC
RKFNQFACDDDALRSLSGE
HHCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]