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The map label for this gene is guaA [H]

Identifier: 83592908

GI number: 83592908

Start: 1854518

End: 1855051

Strand: Direct

Name: guaA [H]

Synonym: Rru_A1573

Alternate gene names: 83592908

Gene position: 1854518-1855051 (Clockwise)

Preceding gene: 83592907

Following gene: 83592910

Centisome position: 42.6

GC content: 65.54

Gene sequence:

>534_bases
ATGTCGGGCTATTGCGATGCCGCGCCGGGCCATCCCCTCCACGGCCCCTATCATGATACCGAATATGGCTTCCCGCAGAC
CGACGAACGGGTGTTGTTCGAACGTCTGGCCCTGGAGATCTTCCAGGCCGGGCTGTCGTGGGAACTGATCTTGCGCCGCC
GCCCGGGGATTAACGACGCCTTCGACGGCTTCGAGGTCGACCGGGTCGCCGCCTATGACGAGGCCGATATCGCCCGTCTG
CTCGCCGATGCCCGCATCATCCGCAATCGGCTGAAGGTGGTGGCGCTGATCGCCAACGCCCGCCAGATCCAGGCCCTGCG
CGCCAGCCACGGCGGGTTCGCCGCTTGGCTCGCCGCCCAGCCACCCCAGGACCTAAGCCAATGGGTCAAGCTGTTTCGCA
AGACCTTCCGCTTCACCGGCCCCGAGGTGGTCAATGAATTCCTGATGAGCCTTGGCATCCTGGAAGGCGCCCACCGCCCC
GATTGTCCGGTCGCCCTTCACTTGGCCGAGATGAGGCGGAGCGCCACGGTTTAG

Upstream 100 bases:

>100_bases
CAAGGACTTCAACGGCACGCTGGTTGAACTCGAGCAGGCCTGAAGTCTTCTTGAACAGGCCTGAGGCCTTGCTGGCCTAA
ACAAGGAGCGGGGAGGGGAG

Downstream 100 bases:

>100_bases
GGAGGTCTGCGAGGTCTCTACCCGTGCTCGGAGTGGATTCGACGGGGATGGGATGGCCTTCGCCCCCTCTCGCTCTAGAA
TTCAATCACGACGGAGGGCG

Product: DNA-3-methyladenine glycosylase I

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MSGYCDAAPGHPLHGPYHDTEYGFPQTDERVLFERLALEIFQAGLSWELILRRRPGINDAFDGFEVDRVAAYDEADIARL
LADARIIRNRLKVVALIANARQIQALRASHGGFAAWLAAQPPQDLSQWVKLFRKTFRFTGPEVVNEFLMSLGILEGAHRP
DCPVALHLAEMRRSATV

Sequences:

>Translated_177_residues
MSGYCDAAPGHPLHGPYHDTEYGFPQTDERVLFERLALEIFQAGLSWELILRRRPGINDAFDGFEVDRVAAYDEADIARL
LADARIIRNRLKVVALIANARQIQALRASHGGFAAWLAAQPPQDLSQWVKLFRKTFRFTGPEVVNEFLMSLGILEGAHRP
DCPVALHLAEMRRSATV
>Mature_176_residues
SGYCDAAPGHPLHGPYHDTEYGFPQTDERVLFERLALEIFQAGLSWELILRRRPGINDAFDGFEVDRVAAYDEADIARLL
ADARIIRNRLKVVALIANARQIQALRASHGGFAAWLAAQPPQDLSQWVKLFRKTFRFTGPEVVNEFLMSLGILEGAHRPD
CPVALHLAEMRRSATV

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 N-acetyltransferase domains [H]

Homologues:

Organism=Escherichia coli, GI1789971, Length=169, Percent_Identity=31.9526627218935, Blast_Score=93, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005019
- InterPro:   IPR001962
- InterPro:   IPR001317
- InterPro:   IPR011257
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF03352 Adenine_glyco; PF00733 Asn_synthase; PF00117 GATase; PF00958 GMP_synt_C [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 19866; Mature: 19735

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGYCDAAPGHPLHGPYHDTEYGFPQTDERVLFERLALEIFQAGLSWELILRRRPGINDA
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCC
FDGFEVDRVAAYDEADIARLLADARIIRNRLKVVALIANARQIQALRASHGGFAAWLAAQ
CCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
PPQDLSQWVKLFRKTFRFTGPEVVNEFLMSLGILEGAHRPDCPVALHLAEMRRSATV
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGYCDAAPGHPLHGPYHDTEYGFPQTDERVLFERLALEIFQAGLSWELILRRRPGINDA
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCC
FDGFEVDRVAAYDEADIARLLADARIIRNRLKVVALIANARQIQALRASHGGFAAWLAAQ
CCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
PPQDLSQWVKLFRKTFRFTGPEVVNEFLMSLGILEGAHRPDCPVALHLAEMRRSATV
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954 [H]