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The map label for this gene is dctB [H]

Identifier: 83592772

GI number: 83592772

Start: 1697495

End: 1699348

Strand: Reverse

Name: dctB [H]

Synonym: Rru_A1436

Alternate gene names: 83592772

Gene position: 1699348-1697495 (Counterclockwise)

Preceding gene: 83592777

Following gene: 83592771

Centisome position: 39.04

GC content: 68.93

Gene sequence:

>1854_bases
GTGACAACGCAGGCGCTATCGCCGGGCCGGGCCAGCCGGTGGCCCAGGCTTGGCTGGCGGCATTGGGCCGCCCTTGCCCT
GGCGCTTTTGGTGCTGTTTGGCCTTGACCGCCTGTCCCAGGCCGGGGCGCAAAGCTGGACCCTGTCCCATGCCCGCGATG
CCGCCAGGGCGGCCTGGACCTCGCGCGCCGCCGTCTTGCAAAGCGAGATCGAGAAGCAGCGCTCGCTGCCCCTGGTGCTG
GCCAGCGATCCCGATCTTGGCCGCGCCCTGGAAAGCCGCGATCCGGCCCATATCGCCGCCCTGAACGAGAAATTCGAAAC
CCTGGCGGCGGGCACCCGGGCCGGGGTCATCTATCTGCTTGATCTGGGCGGGGTCGCCATCGCCGCCAGCAACTGGCGGG
CGGCCGACAGCTTCGTCGGTTCGGATTACGGCTTTCGCCCCTATTTCCGCTTGGCGCTTGACGAAAGGGCGACCGAGCAT
TTCGCCCTGGGCACGGTCAGCCATCGCCCGGGGCTTTACATCGCCCGACGCATCGACGGCGCCCGGGGCCCCTTGGGCGT
TCTGGTGGTGAAGGTCGAGTTCGAGACCATCGAGGCGCAGTGGCAGGGCTTTGCCGAACCAACCTTCGTCACCGACGCCC
AGGGCGTGGTCATCATCACCAGCCTGCCCTCCTGGCGCTTTCTGGCCGAGATCCCGAAATCGGCCGAAGAAAGCGCCCGC
ATCCGCGCCTCCCTGCCCTTCGAGAAAGCCCCGTTGACGCCGCTGCCGATCCGGCGGGCCGACGCCGTCGGCACCGTCGT
CGTCGCCCTGCCGACCTCCCGGGCCGACCGCGCCAATGAAAGGCCCTTCGTGCTTGAAGCCGGACCCCAGCCGGCGACGG
CCTGGACGCTGCATGTCCTGGCCCCGGCCCGGGTTCCCGCCGCCGTGGCCGCCGCCGCCCGCACCTTCGCCTTGATGCTG
AGCACCGGGGTGATCTGCGGGTCGGGCCTGTGGTATGCGCGCTCGCTGCGACGGGCGCGCGAAAGGGGCCGCCAGCGCGC
CGCCCGCATCGAACTGGAAGAGCGCGTTAGCGAACGCACCGCCGAGCTGCGCAGCGCCAATGACCGCCTGCTGACCGAGA
TCGACGAGCGCCGCCGGGCCGAGGCCGCCTTGCAAGACTTGCAAGACGAACTGGTTCAGGCCCGCAAACTGGCCGTTCTT
GGCCAGATCGCCGCCAGCGTCGCCCATGAGATCAACCAGCCGGTGGCCGCCATCCGCACCTTCGCCGACAATGCCCGCAT
CTTCCTGGCCCGCGCCCAGCCCGAGGGCGCCGATCACAACTTGCAAACCATCGCCACCCTGACCGAACGCATCGGCGCCA
TCACCGGCGAATTGCGCGCTTTCGCCCGCAAAAGCCCCAGCCGGGTCGAACCGGTGTCGCTGCGCTCGGCCATCGATGGC
GCCCTGTTGCTGGTTGGCCATCGCCTGCGTCAACAGGCCGTCACCCTGGGCGTTGACATCGCCGAGGGCGATCTGACGGT
GGCGGCCGAACGGGTTCGCCTTGAACAGGTGCTGGTCAATCTTTTGCAAAACGCCGTCGAAGCCCTGGCCGGCCGGCGCG
ACGGGACGATCCGCATCGCCGCCATCGCCGATCGGGCGCGGGTGACCGTTACCGTGTGCGATAACGGACCGGGATTATCC
CCCGATGTCGTCGGATCGCTGTTCATGCCCTTCACCACCACCAAGCCGACCGGTCTTGGCCTCGGGCTGGTGATCGCCAA
GGACATCATCGCCGAGTTCGGCGGCAGCTTCACCGGCGAGAACGCGGCAAGCGGCGGGGCGCGGTTCACCATTACCCTGG
CGAGGCCCCAATGA

Upstream 100 bases:

>100_bases
TATCGATGACCCGGGATTGGACTAGACAACGCGTGCGGATTCCCGGACAATCGATGCCCAAGAAATGCGAATTTCCGCAC
AGAGCAGGACGCCACGAGCC

Downstream 100 bases:

>100_bases
TCGACGTGGCGTTTATCGACGACGACGACACCATGCGCGCCGCCAATGTCCAGGCGCTGACCCTGGCCGGACTGACCGTC
GCCCCCTTCGCCCTGCCCCA

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 617; Mature: 616

Protein sequence:

>617_residues
MTTQALSPGRASRWPRLGWRHWAALALALLVLFGLDRLSQAGAQSWTLSHARDAARAAWTSRAAVLQSEIEKQRSLPLVL
ASDPDLGRALESRDPAHIAALNEKFETLAAGTRAGVIYLLDLGGVAIAASNWRAADSFVGSDYGFRPYFRLALDERATEH
FALGTVSHRPGLYIARRIDGARGPLGVLVVKVEFETIEAQWQGFAEPTFVTDAQGVVIITSLPSWRFLAEIPKSAEESAR
IRASLPFEKAPLTPLPIRRADAVGTVVVALPTSRADRANERPFVLEAGPQPATAWTLHVLAPARVPAAVAAAARTFALML
STGVICGSGLWYARSLRRARERGRQRAARIELEERVSERTAELRSANDRLLTEIDERRRAEAALQDLQDELVQARKLAVL
GQIAASVAHEINQPVAAIRTFADNARIFLARAQPEGADHNLQTIATLTERIGAITGELRAFARKSPSRVEPVSLRSAIDG
ALLLVGHRLRQQAVTLGVDIAEGDLTVAAERVRLEQVLVNLLQNAVEALAGRRDGTIRIAAIADRARVTVTVCDNGPGLS
PDVVGSLFMPFTTTKPTGLGLGLVIAKDIIAEFGGSFTGENAASGGARFTITLARPQ

Sequences:

>Translated_617_residues
MTTQALSPGRASRWPRLGWRHWAALALALLVLFGLDRLSQAGAQSWTLSHARDAARAAWTSRAAVLQSEIEKQRSLPLVL
ASDPDLGRALESRDPAHIAALNEKFETLAAGTRAGVIYLLDLGGVAIAASNWRAADSFVGSDYGFRPYFRLALDERATEH
FALGTVSHRPGLYIARRIDGARGPLGVLVVKVEFETIEAQWQGFAEPTFVTDAQGVVIITSLPSWRFLAEIPKSAEESAR
IRASLPFEKAPLTPLPIRRADAVGTVVVALPTSRADRANERPFVLEAGPQPATAWTLHVLAPARVPAAVAAAARTFALML
STGVICGSGLWYARSLRRARERGRQRAARIELEERVSERTAELRSANDRLLTEIDERRRAEAALQDLQDELVQARKLAVL
GQIAASVAHEINQPVAAIRTFADNARIFLARAQPEGADHNLQTIATLTERIGAITGELRAFARKSPSRVEPVSLRSAIDG
ALLLVGHRLRQQAVTLGVDIAEGDLTVAAERVRLEQVLVNLLQNAVEALAGRRDGTIRIAAIADRARVTVTVCDNGPGLS
PDVVGSLFMPFTTTKPTGLGLGLVIAKDIIAEFGGSFTGENAASGGARFTITLARPQ
>Mature_616_residues
TTQALSPGRASRWPRLGWRHWAALALALLVLFGLDRLSQAGAQSWTLSHARDAARAAWTSRAAVLQSEIEKQRSLPLVLA
SDPDLGRALESRDPAHIAALNEKFETLAAGTRAGVIYLLDLGGVAIAASNWRAADSFVGSDYGFRPYFRLALDERATEHF
ALGTVSHRPGLYIARRIDGARGPLGVLVVKVEFETIEAQWQGFAEPTFVTDAQGVVIITSLPSWRFLAEIPKSAEESARI
RASLPFEKAPLTPLPIRRADAVGTVVVALPTSRADRANERPFVLEAGPQPATAWTLHVLAPARVPAAVAAAARTFALMLS
TGVICGSGLWYARSLRRARERGRQRAARIELEERVSERTAELRSANDRLLTEIDERRRAEAALQDLQDELVQARKLAVLG
QIAASVAHEINQPVAAIRTFADNARIFLARAQPEGADHNLQTIATLTERIGAITGELRAFARKSPSRVEPVSLRSAIDGA
LLLVGHRLRQQAVTLGVDIAEGDLTVAAERVRLEQVLVNLLQNAVEALAGRRDGTIRIAAIADRARVTVTVCDNGPGLSP
DVVGSLFMPFTTTKPTGLGLGLVIAKDIIAEFGGSFTGENAASGGARFTITLARPQ

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=237, Percent_Identity=32.4894514767932, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1788549, Length=271, Percent_Identity=31.3653136531365, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1787894, Length=224, Percent_Identity=29.9107142857143, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789149, Length=278, Percent_Identity=24.1007194244604, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790861, Length=252, Percent_Identity=30.1587301587302, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66453; Mature: 66322

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQALSPGRASRWPRLGWRHWAALALALLVLFGLDRLSQAGAQSWTLSHARDAARAAWT
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHH
SRAAVLQSEIEKQRSLPLVLASDPDLGRALESRDPAHIAALNEKFETLAAGTRAGVIYLL
HHHHHHHHHHHHHHCCCEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEE
DLGGVAIAASNWRAADSFVGSDYGFRPYFRLALDERATEHFALGTVSHRPGLYIARRIDG
ECCCEEEEECCCCCHHHHCCCCCCCCCCEEEEHHHHCHHHEEEEEECCCCCEEEEEECCC
ARGPLGVLVVKVEFETIEAQWQGFAEPTFVTDAQGVVIITSLPSWRFLAEIPKSAEESAR
CCCCEEEEEEEEEEEEHHHHHCCCCCCCEEECCCCEEEEECCCCHHHHHHCCCCCHHHCE
IRASLPFEKAPLTPLPIRRADAVGTVVVALPTSRADRANERPFVLEAGPQPATAWTLHVL
EEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCEEEEEEE
APARVPAAVAAAARTFALMLSTGVICGSGLWYARSLRRARERGRQRAARIELEERVSERT
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AELRSANDRLLTEIDERRRAEAALQDLQDELVQARKLAVLGQIAASVAHEINQPVAAIRT
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
FADNARIFLARAQPEGADHNLQTIATLTERIGAITGELRAFARKSPSRVEPVSLRSAIDG
HCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCH
ALLLVGHRLRQQAVTLGVDIAEGDLTVAAERVRLEQVLVNLLQNAVEALAGRRDGTIRIA
HHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
AIADRARVTVTVCDNGPGLSPDVVGSLFMPFTTTKPTGLGLGLVIAKDIIAEFGGSFTGE
EEECCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
NAASGGARFTITLARPQ
CCCCCCCEEEEEEECCC
>Mature Secondary Structure 
TTQALSPGRASRWPRLGWRHWAALALALLVLFGLDRLSQAGAQSWTLSHARDAARAAWT
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHH
SRAAVLQSEIEKQRSLPLVLASDPDLGRALESRDPAHIAALNEKFETLAAGTRAGVIYLL
HHHHHHHHHHHHHHCCCEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEE
DLGGVAIAASNWRAADSFVGSDYGFRPYFRLALDERATEHFALGTVSHRPGLYIARRIDG
ECCCEEEEECCCCCHHHHCCCCCCCCCCEEEEHHHHCHHHEEEEEECCCCCEEEEEECCC
ARGPLGVLVVKVEFETIEAQWQGFAEPTFVTDAQGVVIITSLPSWRFLAEIPKSAEESAR
CCCCEEEEEEEEEEEEHHHHHCCCCCCCEEECCCCEEEEECCCCHHHHHHCCCCCHHHCE
IRASLPFEKAPLTPLPIRRADAVGTVVVALPTSRADRANERPFVLEAGPQPATAWTLHVL
EEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCEEEEEEE
APARVPAAVAAAARTFALMLSTGVICGSGLWYARSLRRARERGRQRAARIELEERVSERT
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AELRSANDRLLTEIDERRRAEAALQDLQDELVQARKLAVLGQIAASVAHEINQPVAAIRT
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
FADNARIFLARAQPEGADHNLQTIATLTERIGAITGELRAFARKSPSRVEPVSLRSAIDG
HCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCH
ALLLVGHRLRQQAVTLGVDIAEGDLTVAAERVRLEQVLVNLLQNAVEALAGRRDGTIRIA
HHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
AIADRARVTVTVCDNGPGLSPDVVGSLFMPFTTTKPTGLGLGLVIAKDIIAEFGGSFTGE
EEECCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
NAASGGARFTITLARPQ
CCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431; 2551890; 2695394 [H]