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The map label for this gene is nadB [H]

Identifier: 83592769

GI number: 83592769

Start: 1691241

End: 1692839

Strand: Reverse

Name: nadB [H]

Synonym: Rru_A1433

Alternate gene names: 83592769

Gene position: 1692839-1691241 (Counterclockwise)

Preceding gene: 83592770

Following gene: 83592768

Centisome position: 38.89

GC content: 74.11

Gene sequence:

>1599_bases
ATGGCCAGCGTTTCGCCCGACGCGCCGGTGGTGATCGTCGGCGGTGGTCTGGCCGGGCTGTTTTGCGCCCTGAAGCTGGC
GCCACGCCCGGTCACCCTGGTTGTCGCCGCCCCCTTGGGCCAGGGCAGTTCCTCTGCCTGGGCCCAGGGGGGCATCGCCG
CCGCCCTGGGCGACGACGACAGCGCCAGCGCCCATGCCCGCGATACCATCGCCGCCGGCGCCGGCCTTGTCGATCCGCTG
AGCGCGAGCATCCTTGCCGGGGAGGCCGGGGCGCGGATCACCGATCTTCTTGGCTATGGCGTGCCCTTTGATCGCGACGC
CGCCGGCCGGCTTGTGTTGTCGCGCGAAGCCGCCCATTCGGCGCGGCGCATCGTGCGGGTGCGCGGCGATGGCGCCGGGG
CGGCGATCATGGCCGCCCTGATCGGCACGGTTGGCCGCACACCCTCGATCCGGGTGATCGAAGGCGTGGCCGAGGGGCTT
CTAAGCGATGGCCAAAGGATCGGCGGGATCGTGGTGCGCCCCCGCCCCGACGCGGCGGCCGAGGCCCTGGCGGCGGGCGC
CGTCGTGCTGGCTTCGGGGGGCGTCGGCGCCCTCTATGGCGTCACCACCAATCCGCCCGAGGCTTTCGGCGGCGGCTTGG
CGATGGCGGCCGAGGCCGGCGCCTTGCTCGCCGATTGCGAATTCGTGCAGTTCCACCCCACTGCCCTCGCCGTTGGCCTT
GATCCGGCGCCGCTGGCCACCGAGGCCCTGCGCGGCGAGGGGGCGATCCTGGTCGATGCCCAAGGCCGGCGCTTCATGAC
CGCCCTCGACCCCGCCGCCGAGCTTGCGCCGCGCGATGTGGTGACCCGGGGGGTGGCGGCGGCGATCAAGGCCGGCAAGG
GCGCCTTCCTGGATGCCCGCACCGCCCTTGGTGCGGCCTTTCCGCAAGCTTTCCCAACGGTTTACGCGGCCTGTCGCGCC
TCGGGGATCGATCCGGTCCGCCAACCGATCCCGATCGCCCCCGCCGCCCATTATCACATGGGTGGGGTGCTGACCGACAG
CTTCGGCCGCACATCGATCGACGGGCTGTGGGCGGTTGGCGAGGTCGCCTGCACGGGGGCCCATGGCGCCAATCGTCTGG
CCTCGAACTCCTTGCTCGAAGCCGTGGTCTTCGCCGCCCGGGTGGCCGGGGATGTGGGCGCCGCCCCGCTCCGCCGCGGC
TGGCCGCCGCCGGCGCCGCCCGACCTTTCCCCCCGCCCCCCACCGGCCGAGGACGCCGCCGCCATCACCCGCCTGCGGGC
AACGATGAGCGCCCGGGTCGGCGTGATCCGCGACGGCCAGGGCCTGGAAAGCGCCCTGGCGACGATCGAAACCATCGCCG
CTGGCGCCCGCTCGCCCCGCCTGCGCGCCATGACCACCGCCGCCCGGCTGATCACCGCCGCCGCCCTGGCGCGGCGCGAA
AGCCGGGGCGCCCATTTCCGCGCCGATTATCCGGCGACCGATCCGGCGCAAAGCCACCGCGCGACGGCGCCGTTTGGCCC
CTTGCGCACCGTTCCGCCCCACCCCGCCCAGAGCCTGGGGGAGGGTCTGGCCGCACCCCCGATGGAGACCCGCTCATGA

Upstream 100 bases:

>100_bases
TGCCTGCGAACCCTTGGCGGCGAGATCACCATCGATCCGGCCGTGGCCGAGGGGGCGCGGCGGTCGGTGAGGCGCATGAT
CGATCTGGGGAGTTGAGGAC

Downstream 100 bases:

>100_bases
GGCCGAACCACCCCGTTGCCGCGCTGTCGCCCTTCGCCATCGACGAGGCGGTGCGCCGCGCCCTTGCCGAAGACCTGGGG
CGAGCCGGCGATATCACCTC

Product: L-aspartate oxidase

Products: NA

Alternate protein names: LASPO; Quinolinate synthase B [H]

Number of amino acids: Translated: 532; Mature: 531

Protein sequence:

>532_residues
MASVSPDAPVVIVGGGLAGLFCALKLAPRPVTLVVAAPLGQGSSSAWAQGGIAAALGDDDSASAHARDTIAAGAGLVDPL
SASILAGEAGARITDLLGYGVPFDRDAAGRLVLSREAAHSARRIVRVRGDGAGAAIMAALIGTVGRTPSIRVIEGVAEGL
LSDGQRIGGIVVRPRPDAAAEALAAGAVVLASGGVGALYGVTTNPPEAFGGGLAMAAEAGALLADCEFVQFHPTALAVGL
DPAPLATEALRGEGAILVDAQGRRFMTALDPAAELAPRDVVTRGVAAAIKAGKGAFLDARTALGAAFPQAFPTVYAACRA
SGIDPVRQPIPIAPAAHYHMGGVLTDSFGRTSIDGLWAVGEVACTGAHGANRLASNSLLEAVVFAARVAGDVGAAPLRRG
WPPPAPPDLSPRPPPAEDAAAITRLRATMSARVGVIRDGQGLESALATIETIAAGARSPRLRAMTTAARLITAAALARRE
SRGAHFRADYPATDPAQSHRATAPFGPLRTVPPHPAQSLGEGLAAPPMETRS

Sequences:

>Translated_532_residues
MASVSPDAPVVIVGGGLAGLFCALKLAPRPVTLVVAAPLGQGSSSAWAQGGIAAALGDDDSASAHARDTIAAGAGLVDPL
SASILAGEAGARITDLLGYGVPFDRDAAGRLVLSREAAHSARRIVRVRGDGAGAAIMAALIGTVGRTPSIRVIEGVAEGL
LSDGQRIGGIVVRPRPDAAAEALAAGAVVLASGGVGALYGVTTNPPEAFGGGLAMAAEAGALLADCEFVQFHPTALAVGL
DPAPLATEALRGEGAILVDAQGRRFMTALDPAAELAPRDVVTRGVAAAIKAGKGAFLDARTALGAAFPQAFPTVYAACRA
SGIDPVRQPIPIAPAAHYHMGGVLTDSFGRTSIDGLWAVGEVACTGAHGANRLASNSLLEAVVFAARVAGDVGAAPLRRG
WPPPAPPDLSPRPPPAEDAAAITRLRATMSARVGVIRDGQGLESALATIETIAAGARSPRLRAMTTAARLITAAALARRE
SRGAHFRADYPATDPAQSHRATAPFGPLRTVPPHPAQSLGEGLAAPPMETRS
>Mature_531_residues
ASVSPDAPVVIVGGGLAGLFCALKLAPRPVTLVVAAPLGQGSSSAWAQGGIAAALGDDDSASAHARDTIAAGAGLVDPLS
ASILAGEAGARITDLLGYGVPFDRDAAGRLVLSREAAHSARRIVRVRGDGAGAAIMAALIGTVGRTPSIRVIEGVAEGLL
SDGQRIGGIVVRPRPDAAAEALAAGAVVLASGGVGALYGVTTNPPEAFGGGLAMAAEAGALLADCEFVQFHPTALAVGLD
PAPLATEALRGEGAILVDAQGRRFMTALDPAAELAPRDVVTRGVAAAIKAGKGAFLDARTALGAAFPQAFPTVYAACRAS
GIDPVRQPIPIAPAAHYHMGGVLTDSFGRTSIDGLWAVGEVACTGAHGANRLASNSLLEAVVFAARVAGDVGAAPLRRGW
PPPAPPDLSPRPPPAEDAAAITRLRATMSARVGVIRDGQGLESALATIETIAAGARSPRLRAMTTAARLITAAALARRES
RGAHFRADYPATDPAQSHRATAPFGPLRTVPPHPAQSLGEGLAAPPMETRS

Specific function: Catalyzes the oxidation of L-aspartate to iminoaspartate [H]

COG id: COG0029

COG function: function code H; Aspartate oxidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily [H]

Homologues:

Organism=Homo sapiens, GI156416003, Length=505, Percent_Identity=31.0891089108911, Blast_Score=191, Evalue=1e-48,
Organism=Escherichia coli, GI1788928, Length=519, Percent_Identity=39.1136801541426, Blast_Score=306, Evalue=2e-84,
Organism=Escherichia coli, GI1790597, Length=511, Percent_Identity=31.1154598825832, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI1786942, Length=513, Percent_Identity=30.7992202729045, Blast_Score=167, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17505833, Length=525, Percent_Identity=29.7142857142857, Blast_Score=183, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17550100, Length=522, Percent_Identity=29.3103448275862, Blast_Score=172, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI71986328, Length=286, Percent_Identity=28.3216783216783, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322701, Length=517, Percent_Identity=32.6885880077369, Blast_Score=211, Evalue=3e-55,
Organism=Saccharomyces cerevisiae, GI6322416, Length=549, Percent_Identity=30.6010928961749, Blast_Score=197, Evalue=3e-51,
Organism=Drosophila melanogaster, GI17137288, Length=522, Percent_Identity=30.4597701149425, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24655642, Length=522, Percent_Identity=30.4597701149425, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24655647, Length=522, Percent_Identity=30.4597701149425, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24663005, Length=532, Percent_Identity=29.1353383458647, Blast_Score=181, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR015939
- InterPro:   IPR004112
- InterPro:   IPR005288 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF02910 Succ_DH_flav_C [H]

EC number: =1.4.3.16 [H]

Molecular weight: Translated: 53312; Mature: 53181

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASVSPDAPVVIVGGGLAGLFCALKLAPRPVTLVVAAPLGQGSSSAWAQGGIAAALGDDD
CCCCCCCCCEEEECCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHCCCEEEEECCCC
SASAHARDTIAAGAGLVDPLSASILAGEAGARITDLLGYGVPFDRDAAGRLVLSREAAHS
CCCCHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCEEEEHHHHHH
ARRIVRVRGDGAGAAIMAALIGTVGRTPSIRVIEGVAEGLLSDGQRIGGIVVRPRPDAAA
HHEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHCCEEEECCCCHHH
EALAAGAVVLASGGVGALYGVTTNPPEAFGGGLAMAAEAGALLADCEFVQFHPTALAVGL
HHHHHCEEEEECCCCEEEEECCCCCHHHHCCCEEHHHHCCCCEECCEEEEECCCEEEECC
DPAPLATEALRGEGAILVDAQGRRFMTALDPAAELAPRDVVTRGVAAAIKAGKGAFLDAR
CCCCHHHHHHCCCCEEEEECCCCEEEECCCHHHHHCCHHHHHHHHHHHHHCCCCCEEEHH
TALGAAFPQAFPTVYAACRASGIDPVRQPIPIAPAAHYHMGGVLTDSFGRTSIDGLWAVG
HHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHCCCEEECCCCCCCCCCCEEHH
EVACTGAHGANRLASNSLLEAVVFAARVAGDVGAAPLRRGWPPPAPPDLSPRPPPAEDAA
HEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCHHHH
AITRLRATMSARVGVIRDGQGLESALATIETIAAGARSPRLRAMTTAARLITAAALARRE
HHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
SRGAHFRADYPATDPAQSHRATAPFGPLRTVPPHPAQSLGEGLAAPPMETRS
HCCCEEECCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
ASVSPDAPVVIVGGGLAGLFCALKLAPRPVTLVVAAPLGQGSSSAWAQGGIAAALGDDD
CCCCCCCCEEEECCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHCCCEEEEECCCC
SASAHARDTIAAGAGLVDPLSASILAGEAGARITDLLGYGVPFDRDAAGRLVLSREAAHS
CCCCHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCEEEEHHHHHH
ARRIVRVRGDGAGAAIMAALIGTVGRTPSIRVIEGVAEGLLSDGQRIGGIVVRPRPDAAA
HHEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHCCEEEECCCCHHH
EALAAGAVVLASGGVGALYGVTTNPPEAFGGGLAMAAEAGALLADCEFVQFHPTALAVGL
HHHHHCEEEEECCCCEEEEECCCCCHHHHCCCEEHHHHCCCCEECCEEEEECCCEEEECC
DPAPLATEALRGEGAILVDAQGRRFMTALDPAAELAPRDVVTRGVAAAIKAGKGAFLDAR
CCCCHHHHHHCCCCEEEEECCCCEEEECCCHHHHHCCHHHHHHHHHHHHHCCCCCEEEHH
TALGAAFPQAFPTVYAACRASGIDPVRQPIPIAPAAHYHMGGVLTDSFGRTSIDGLWAVG
HHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHCCCEEECCCCCCCCCCCEEHH
EVACTGAHGANRLASNSLLEAVVFAARVAGDVGAAPLRRGWPPPAPPDLSPRPPPAEDAA
HEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCHHHH
AITRLRATMSARVGVIRDGQGLESALATIETIAAGARSPRLRAMTTAARLITAAALARRE
HHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
SRGAHFRADYPATDPAQSHRATAPFGPLRTVPPHPAQSLGEGLAAPPMETRS
HCCCEEECCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]