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The map label for this gene is nadA [H]

Identifier: 83592770

GI number: 83592770

Start: 1692844

End: 1693875

Strand: Reverse

Name: nadA [H]

Synonym: Rru_A1434

Alternate gene names: 83592770

Gene position: 1693875-1692844 (Counterclockwise)

Preceding gene: 83592771

Following gene: 83592769

Centisome position: 38.91

GC content: 65.7

Gene sequence:

>1032_bases
ATGCCTTTCGCCTCTGACCGTGCCGCGACGACGCTTGCCGATCTGTCGTGGTCGGCCGAGGTCGAGCGCGAGAGCGCGGC
GCTTTATGAAAAGGTGGCGCGGGTGGTGCCGCCGGTTGAATGGCGGGTGTTCGCGCCGCTAATCCTGGCGATCAACGCCC
TGAAGGCCGAGCGCGGCGCCGTCATCCTCGCCCATAGCTATCAAACGCCCGAGATCTACCATTGCGTCGCCGATATCGTG
GGCGATTCGCTTCAGTTGGCGCGCCAAGCCGCCGAGGTCGAGGCCGATATTCTGGTGCAATGCGGCGTGCATTTCATGGC
CGAAACCGCGAAGCTGCTCAATCCGACCAAAAGGGTGCTCTGCCCCGATCCGGGCGCGGGCTGCTCGCTGGCCGCCTCGA
TCACCGCCGCCGATGTCCGGGCGTTGCGCCGACGCCACCCCGGCGTGCCGATCGTCGCCTATGTCAATACCTCGGCGACG
GTGAAGGCCGAGGTTGATATCTGCTGCACCTCGTCAAACGCGCTCGCCGTGGTCGAAAGCCTGGGGGCGCCCCGGGTGAT
CCTGGTTCCCGATCGTTATCTCGCGACCTATGTCGCCTCGCAAACCACCGTCGAGATCATCGCTTGGCCGGGGGCCTGCG
AGGTTCACGAGCGCTTCACCGGCGAGGACATCGCCCGCTACCGCGAGGGGGATGGCGATCTGCGCATCATCGCCCATCCC
GAATGCCCGCCCGATGTCATCGCCGCCAGCGATTTCACCGGCTCGACCTCGGCGATGATCGCCTGGGTCAGGGCCAACCG
GCCGCGCCGGGTGGCGCTGATCACCGAATGCTCGATGGCCGATAATCTTGCCGCCGAGATGCCCGAAACCGACTTCGTGC
GCCCGTGCAACCTCTGTCCGCACATGAAAAAGATCACCCTAACCAAGATCCTCGCGTGCCTGCGAACCCTTGGCGGCGAG
ATCACCATCGATCCGGCCGTGGCCGAGGGGGCGCGGCGGTCGGTGAGGCGCATGATCGATCTGGGGAGTTGA

Upstream 100 bases:

>100_bases
GCCGGATTTTGCGCTACCTTATATTTGCTCACTTTGAGCATAACGCGCTTCGGCGCGGAGGACCGGTGGCTTTCGCGAGG
GACCGATGACGGGATTGGAG

Downstream 100 bases:

>100_bases
GGACATGGCCAGCGTTTCGCCCGACGCGCCGGTGGTGATCGTCGGCGGTGGTCTGGCCGGGCTGTTTTGCGCCCTGAAGC
TGGCGCCACGCCCGGTCACC

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MPFASDRAATTLADLSWSAEVERESAALYEKVARVVPPVEWRVFAPLILAINALKAERGAVILAHSYQTPEIYHCVADIV
GDSLQLARQAAEVEADILVQCGVHFMAETAKLLNPTKRVLCPDPGAGCSLAASITAADVRALRRRHPGVPIVAYVNTSAT
VKAEVDICCTSSNALAVVESLGAPRVILVPDRYLATYVASQTTVEIIAWPGACEVHERFTGEDIARYREGDGDLRIIAHP
ECPPDVIAASDFTGSTSAMIAWVRANRPRRVALITECSMADNLAAEMPETDFVRPCNLCPHMKKITLTKILACLRTLGGE
ITIDPAVAEGARRSVRRMIDLGS

Sequences:

>Translated_343_residues
MPFASDRAATTLADLSWSAEVERESAALYEKVARVVPPVEWRVFAPLILAINALKAERGAVILAHSYQTPEIYHCVADIV
GDSLQLARQAAEVEADILVQCGVHFMAETAKLLNPTKRVLCPDPGAGCSLAASITAADVRALRRRHPGVPIVAYVNTSAT
VKAEVDICCTSSNALAVVESLGAPRVILVPDRYLATYVASQTTVEIIAWPGACEVHERFTGEDIARYREGDGDLRIIAHP
ECPPDVIAASDFTGSTSAMIAWVRANRPRRVALITECSMADNLAAEMPETDFVRPCNLCPHMKKITLTKILACLRTLGGE
ITIDPAVAEGARRSVRRMIDLGS
>Mature_342_residues
PFASDRAATTLADLSWSAEVERESAALYEKVARVVPPVEWRVFAPLILAINALKAERGAVILAHSYQTPEIYHCVADIVG
DSLQLARQAAEVEADILVQCGVHFMAETAKLLNPTKRVLCPDPGAGCSLAASITAADVRALRRRHPGVPIVAYVNTSATV
KAEVDICCTSSNALAVVESLGAPRVILVPDRYLATYVASQTTVEIIAWPGACEVHERFTGEDIARYREGDGDLRIIAHPE
CPPDVIAASDFTGSTSAMIAWVRANRPRRVALITECSMADNLAAEMPETDFVRPCNLCPHMKKITLTKILACLRTLGGEI
TIDPAVAEGARRSVRRMIDLGS

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=311, Percent_Identity=34.0836012861736, Blast_Score=164, Evalue=6e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 36997; Mature: 36866

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFASDRAATTLADLSWSAEVERESAALYEKVARVVPPVEWRVFAPLILAINALKAERGA
CCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCE
VILAHSYQTPEIYHCVADIVGDSLQLARQAAEVEADILVQCGVHFMAETAKLLNPTKRVL
EEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
CPDPGAGCSLAASITAADVRALRRRHPGVPIVAYVNTSATVKAEVDICCTSSNALAVVES
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEEEEEEEECCCHHHHHHH
LGAPRVILVPDRYLATYVASQTTVEIIAWPGACEVHERFTGEDIARYREGDGDLRIIAHP
CCCCEEEEECCHHHHHHHHCCCEEEEEECCCCCHHHHHCCHHHHHHHHCCCCCEEEEECC
ECPPDVIAASDFTGSTSAMIAWVRANRPRRVALITECSMADNLAAEMPETDFVRPCNLCP
CCCCCCEEECCCCCCHHHEEEEEECCCCCEEEEEEECCHHHHHHHCCCCCCCCCCCCCCC
HMKKITLTKILACLRTLGGEITIDPAVAEGARRSVRRMIDLGS
CHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PFASDRAATTLADLSWSAEVERESAALYEKVARVVPPVEWRVFAPLILAINALKAERGA
CCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCE
VILAHSYQTPEIYHCVADIVGDSLQLARQAAEVEADILVQCGVHFMAETAKLLNPTKRVL
EEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
CPDPGAGCSLAASITAADVRALRRRHPGVPIVAYVNTSATVKAEVDICCTSSNALAVVES
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEEEEEEEECCCHHHHHHH
LGAPRVILVPDRYLATYVASQTTVEIIAWPGACEVHERFTGEDIARYREGDGDLRIIAHP
CCCCEEEEECCHHHHHHHHCCCEEEEEECCCCCHHHHHCCHHHHHHHHCCCCCEEEEECC
ECPPDVIAASDFTGSTSAMIAWVRANRPRRVALITECSMADNLAAEMPETDFVRPCNLCP
CCCCCCEEECCCCCCHHHEEEEEECCCCCEEEEEEECCHHHHHHHCCCCCCCCCCCCCCC
HMKKITLTKILACLRTLGGEITIDPAVAEGARRSVRRMIDLGS
CHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]