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The map label for this gene is ahpC [H]

Identifier: 83592754

GI number: 83592754

Start: 1675458

End: 1676021

Strand: Reverse

Name: ahpC [H]

Synonym: Rru_A1418

Alternate gene names: 83592754

Gene position: 1676021-1675458 (Counterclockwise)

Preceding gene: 83592755

Following gene: 83592753

Centisome position: 38.5

GC content: 61.35

Gene sequence:

>564_bases
ATGTCGTTGATTGGTAGCGAAGTTAAGCCGTTCAAGGCCGACGCATTCAAGGCCGGGAAGTTTGTCACCGTCACCGATGA
CACGCTCAAGGGCAAGTGGTCCGTCGTGTTCTTCTACCCCGCCGACTTCACCTTCGTCTGCCCCACCGAGCTTGAGGACT
TGGCCGAGAACTATGCCGAGTTCCAGCGTCTTGGTGTGGAGATCTTCAGCGTCTCGACCGATACGCATTTCGCCCACAAG
GCATGGCACGACACCTCGGAAGCCATCAAGAAGATCGAGTACACCATGGTCGGCGATCCGACCGGCACGATCAGCCGGAA
CTTCGACGTGCTGATCGAAGACGCCGGCCTCGCCGATCGCGGCACCTTCGTCATCGATCCCGAGGGCCGGATCCAGATCG
TCGAGATCACCGCCGGCGGCATCGGCCGTGACGCCCTGGAGCTTCTGCGCAAGGTCAAGGCCGCCCAGTACGTCGCCTCC
CACCCCGGCGAAGTCTGCCCGGCCAAGTGGAAGGAAGGCGAAAAGACCCTCGCCCCGTCGCTTGATCTGGTCGGCCGTAT
CTAA

Upstream 100 bases:

>100_bases
ATTTTTCCACTGGAATATACATAAAAAACCAATTTCCTTTATGGTTATTCCAGTTCTAGGATGCGCCCTGTTCAGATCAC
ACAACGCAGCGGAGAAGACA

Downstream 100 bases:

>100_bases
ACACCGAGACCACGTCCCCCCTGGATCCGACCCCGGTCGGGCCCAGGGGGAGCGAGACGAAACAGGGTCAAACCATCATC
CGGGCAGCGCACATCCTCGT

Product: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; Peroxiredoxin; SCRP-23; Sulfate starvation-induced protein 8; SSI8; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSLIGSEVKPFKADAFKAGKFVTVTDDTLKGKWSVVFFYPADFTFVCPTELEDLAENYAEFQRLGVEIFSVSTDTHFAHK
AWHDTSEAIKKIEYTMVGDPTGTISRNFDVLIEDAGLADRGTFVIDPEGRIQIVEITAGGIGRDALELLRKVKAAQYVAS
HPGEVCPAKWKEGEKTLAPSLDLVGRI

Sequences:

>Translated_187_residues
MSLIGSEVKPFKADAFKAGKFVTVTDDTLKGKWSVVFFYPADFTFVCPTELEDLAENYAEFQRLGVEIFSVSTDTHFAHK
AWHDTSEAIKKIEYTMVGDPTGTISRNFDVLIEDAGLADRGTFVIDPEGRIQIVEITAGGIGRDALELLRKVKAAQYVAS
HPGEVCPAKWKEGEKTLAPSLDLVGRI
>Mature_186_residues
SLIGSEVKPFKADAFKAGKFVTVTDDTLKGKWSVVFFYPADFTFVCPTELEDLAENYAEFQRLGVEIFSVSTDTHFAHKA
WHDTSEAIKKIEYTMVGDPTGTISRNFDVLIEDAGLADRGTFVIDPEGRIQIVEITAGGIGRDALELLRKVKAAQYVASH
PGEVCPAKWKEGEKTLAPSLDLVGRI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32483377, Length=180, Percent_Identity=43.8888888888889, Blast_Score=150, Evalue=4e-37,
Organism=Homo sapiens, GI5802974, Length=173, Percent_Identity=43.9306358381503, Blast_Score=150, Evalue=8e-37,
Organism=Homo sapiens, GI32189392, Length=182, Percent_Identity=40.6593406593407, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI4505591, Length=182, Percent_Identity=39.010989010989, Blast_Score=135, Evalue=2e-32,
Organism=Homo sapiens, GI32455266, Length=182, Percent_Identity=39.010989010989, Blast_Score=135, Evalue=2e-32,
Organism=Homo sapiens, GI32455264, Length=182, Percent_Identity=39.010989010989, Blast_Score=135, Evalue=2e-32,
Organism=Homo sapiens, GI5453549, Length=164, Percent_Identity=39.0243902439024, Blast_Score=124, Evalue=4e-29,
Organism=Homo sapiens, GI33188454, Length=81, Percent_Identity=45.679012345679, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI1786822, Length=187, Percent_Identity=69.5187165775401, Blast_Score=291, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI17554494, Length=179, Percent_Identity=39.6648044692737, Blast_Score=137, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI32565831, Length=183, Percent_Identity=39.344262295082, Blast_Score=137, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI193204376, Length=183, Percent_Identity=39.344262295082, Blast_Score=137, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI25153706, Length=164, Percent_Identity=26.219512195122, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323613, Length=175, Percent_Identity=36, Blast_Score=114, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6320661, Length=181, Percent_Identity=32.0441988950276, Blast_Score=109, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6319407, Length=164, Percent_Identity=29.8780487804878, Blast_Score=80, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357347, Length=176, Percent_Identity=38.6363636363636, Blast_Score=140, Evalue=4e-34,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=38.9830508474576, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI17157991, Length=170, Percent_Identity=38.2352941176471, Blast_Score=130, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24641739, Length=170, Percent_Identity=38.2352941176471, Blast_Score=130, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24656348, Length=182, Percent_Identity=35.7142857142857, Blast_Score=127, Evalue=3e-30,
Organism=Drosophila melanogaster, GI17864676, Length=182, Percent_Identity=35.7142857142857, Blast_Score=127, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24581278, Length=160, Percent_Identity=30, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI17975518, Length=186, Percent_Identity=27.9569892473118, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24652436, Length=186, Percent_Identity=27.9569892473118, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24652434, Length=186, Percent_Identity=27.9569892473118, Blast_Score=70, Evalue=8e-13,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20588; Mature: 20456

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLIGSEVKPFKADAFKAGKFVTVTDDTLKGKWSVVFFYPADFTFVCPTELEDLAENYAE
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEEECCCEEEECCHHHHHHHHHHHH
FQRLGVEIFSVSTDTHFAHKAWHDTSEAIKKIEYTMVGDPTGTISRNFDVLIEDAGLADR
HHHCCEEEEEEECCCCHHHHHHCCHHHHHHHEEEEEECCCCCCCCCCEEEEEECCCCCCC
GTFVIDPEGRIQIVEITAGGIGRDALELLRKVKAAQYVASHPGEVCPAKWKEGEKTLAPS
CCEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
LDLVGRI
CHHHCCC
>Mature Secondary Structure 
SLIGSEVKPFKADAFKAGKFVTVTDDTLKGKWSVVFFYPADFTFVCPTELEDLAENYAE
CCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEEECCCEEEECCHHHHHHHHHHHH
FQRLGVEIFSVSTDTHFAHKAWHDTSEAIKKIEYTMVGDPTGTISRNFDVLIEDAGLADR
HHHCCEEEEEEECCCCHHHHHHCCHHHHHHHEEEEEECCCCCCCCCCEEEEEECCCCCCC
GTFVIDPEGRIQIVEITAGGIGRDALELLRKVKAAQYVASHPGEVCPAKWKEGEKTLAPS
CCEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
LDLVGRI
CHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]