Click here to switch to the map view.

The map label for this gene is hxlB [H]

Identifier: 83592703

GI number: 83592703

Start: 1608728

End: 1609285

Strand: Reverse

Name: hxlB [H]

Synonym: Rru_A1367

Alternate gene names: 83592703

Gene position: 1609285-1608728 (Counterclockwise)

Preceding gene: 83592704

Following gene: 83592702

Centisome position: 36.97

GC content: 68.46

Gene sequence:

>558_bases
ATGGGACTGAAAGCAACCTGCCTCGCCGCCCTTGATGATCTGCGCGCGGTTTTCGCCACCCTGGACGAAACGGCGACGGA
TCGGGCGGTCGAGGAATTCGTCAAGGCGCGACAGATCGCGCTTTATGGCGTCGGCCGCGAAGGCCTGCAGATCAAAGGTC
TGGCCATGCGCCTCCATCACCTGGGCCTGCGGGTCGCCATGGTCGGCGATATGACCACCCCGCCGCTCGCCGCCGGGGAT
CTGCTGGTGGTCTCGGCCGGGCCCGGAGCGTTCTCAACGGTATCCGCCCTGATGGGGGTGGCCAAGGCCGCCGGGGCGCG
GAGCTTGCTGGTCACCGCCCAGCCGGCGGGGGACTGCGCCCGCTTGGCCGATGTCGTCTTGCCGATCCCGGCCCAGACCA
TGGCCGATGACCAACACCCTTCGGCCAGCATCCTGCCCATGGGATCGGTGTTCGAAGGCGCCGAGTTCATCTTGTTCGAG
GCGCTGGTCCTGGCCCTGCGCGACCGTCTGGCGGTCAGCCCGGAGGCCATGCGGGCGCGCCACACCAACCTGGAGTAG

Upstream 100 bases:

>100_bases
GCCCGGTTATGGGCAAGTCTGACACCCCCCTTGCGCCGGCGACGAGCGGCCCCGGCCCGCTCCCCGGTGCCCGGTGCCCG
CTGGCGAAGGTCTGTATTCC

Downstream 100 bases:

>100_bases
ACCGCACGGGGCCAAGCCGGGTAGAACCGGCGTCCTCTGGCGATGCAACAACATGGAATACCCTGATGGCAGCCGATGAC
GCGGACGGTCTTTCCTCCGA

Product: hexulose-6-phosphate isomerase

Products: NA

Alternate protein names: 6-phospho-3-hexuloisomerase; PHI [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MGLKATCLAALDDLRAVFATLDETATDRAVEEFVKARQIALYGVGREGLQIKGLAMRLHHLGLRVAMVGDMTTPPLAAGD
LLVVSAGPGAFSTVSALMGVAKAAGARSLLVTAQPAGDCARLADVVLPIPAQTMADDQHPSASILPMGSVFEGAEFILFE
ALVLALRDRLAVSPEAMRARHTNLE

Sequences:

>Translated_185_residues
MGLKATCLAALDDLRAVFATLDETATDRAVEEFVKARQIALYGVGREGLQIKGLAMRLHHLGLRVAMVGDMTTPPLAAGD
LLVVSAGPGAFSTVSALMGVAKAAGARSLLVTAQPAGDCARLADVVLPIPAQTMADDQHPSASILPMGSVFEGAEFILFE
ALVLALRDRLAVSPEAMRARHTNLE
>Mature_184_residues
GLKATCLAALDDLRAVFATLDETATDRAVEEFVKARQIALYGVGREGLQIKGLAMRLHHLGLRVAMVGDMTTPPLAAGDL
LVVSAGPGAFSTVSALMGVAKAAGARSLLVTAQPAGDCARLADVVLPIPAQTMADDQHPSASILPMGSVFEGAEFILFEA
LVLALRDRLAVSPEAMRARHTNLE

Specific function: Catalyzes the isomerization between 3-hexulose 6- phosphate and fructose 6-phosphate. Together with hxlA, may act as a formaldehyde detoxification system [H]

COG id: COG0794

COG function: function code M; Predicted sugar phosphate isomerase involved in capsule formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017552
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.27 [H]

Molecular weight: Translated: 19316; Mature: 19185

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLKATCLAALDDLRAVFATLDETATDRAVEEFVKARQIALYGVGREGLQIKGLAMRLHH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEHHHHHHHHH
LGLRVAMVGDMTTPPLAAGDLLVVSAGPGAFSTVSALMGVAKAAGARSLLVTAQPAGDCA
HCEEEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHH
RLADVVLPIPAQTMADDQHPSASILPMGSVFEGAEFILFEALVLALRDRLAVSPEAMRAR
HHHHHHCCCCCHHHCCCCCCCCCEEECCCHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
HTNLE
CCCCC
>Mature Secondary Structure 
GLKATCLAALDDLRAVFATLDETATDRAVEEFVKARQIALYGVGREGLQIKGLAMRLHH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEHHHHHHHHH
LGLRVAMVGDMTTPPLAAGDLLVVSAGPGAFSTVSALMGVAKAAGARSLLVTAQPAGDCA
HCEEEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHH
RLADVVLPIPAQTMADDQHPSASILPMGSVFEGAEFILFEALVLALRDRLAVSPEAMRAR
HHHHHHCCCCCHHHCCCCCCCCCEEECCCHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
HTNLE
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704255; 8969502; 9384377; 7921238 [H]