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The map label for this gene is dhaK [H]

Identifier: 83592676

GI number: 83592676

Start: 1577909

End: 1578913

Strand: Direct

Name: dhaK [H]

Synonym: Rru_A1340

Alternate gene names: 83592676

Gene position: 1577909-1578913 (Clockwise)

Preceding gene: 83592674

Following gene: 83592677

Centisome position: 36.25

GC content: 65.37

Gene sequence:

>1005_bases
ATGAATCGGATCATCAACGACCCGGATCTGGTGGTAGAGGACGCGGTGCGCGGCTATCTGAAGGCGCATCGGGATCTGGT
TCGGCCCACGACGAACCCCCGGGTGATCCGCCACCACTTGGCCCCGCAACAGGGCAAGGTCGGGGTGGTGACCGGCGGCG
GATCGGGGCACGAGCCGGCCTTCCTCGGCTATGTCGGCGACGGCATGATCGACGCCGTGGCGATCGGCGAGATCTTTTCC
TCGCCCACGGCCAAAAGTTTCCATGACGCCTTCGTCGCCGCCGATGGCGGGCGGGGCGTGGCCTGTCTTTATGGCAATTA
CGCCGGCGACAATATGAACGTGAAGCTGGCGGTCAAAAAGGCGGCCTCCCACGATCTGACGGTGAAGACCGTGGTCGCCA
ATGACGATGTGCCGTCGGCCCCCAAGAGCGAGCGCGACAAGCGGCGCGGCGTCGCCGGCGAGATCTTGATGTGGAAGGTG
GGCGGAGCGCGGGCCGCCGAGGGCGCCGATCTTGACGAGGTGATCGCCTCGGCCCAGAAGGCCATCGACGCCACCCGCAG
CATCGGCATCGGCCTGTCGCCCTGCATTATCCCGGCGGTGGGCAAGCCGAACTTCTCCATCGAGAACGGCATGATGGAGG
TGGGCATCGGCCACCATGGCGAACCCGGGGTCGAGGTGGCCCCCGTGCGCCCGGCCAAGGAAATGGCCGATCTGATGCTT
GACCACATCCTGCCCGATCTGCCCTTTGGCCGGGGCGACGATCTGGCGGTGCTGGTCTCGGGTCTGGGCGCCACGCCGGT
GATGGAGCTGTATATCCTCTATGATCGTCTGAGCGAGGTGCTGGAGGATCGGGGGATGACGGTGGTTCATCCCTTCATCG
GCAATTACTTCACGTCGCTGGAGATGATGGGGGTGACGCTGACGGTGATGCGCCTTGATGGCGAACTCGCCCGTCTGGTC
GGCGCGCCGGCCCGCTCCGTCGGTCTTACAAGGATCCCGTCATGA

Upstream 100 bases:

>100_bases
TCGCCTTGGAGCGATCGGGGTGGGCCGCCCGGCGGCGCGATCATGGGTGCTGGTTGGGTGACCGGTGGCGGCTTCGCCAC
GCGCGGAAAAGGGATTATTC

Downstream 100 bases:

>100_bases
CCGGTATTCCCCTCGCCGCCGCCGGCGGTCTCGTCGTTGAACTGATCGAGACCATCAACGCCAATCGCGCCCATCTGTCG
GAAATCGACGGCGCGATCGG

Product: Glycerone kinase

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MNRIINDPDLVVEDAVRGYLKAHRDLVRPTTNPRVIRHHLAPQQGKVGVVTGGGSGHEPAFLGYVGDGMIDAVAIGEIFS
SPTAKSFHDAFVAADGGRGVACLYGNYAGDNMNVKLAVKKAASHDLTVKTVVANDDVPSAPKSERDKRRGVAGEILMWKV
GGARAAEGADLDEVIASAQKAIDATRSIGIGLSPCIIPAVGKPNFSIENGMMEVGIGHHGEPGVEVAPVRPAKEMADLML
DHILPDLPFGRGDDLAVLVSGLGATPVMELYILYDRLSEVLEDRGMTVVHPFIGNYFTSLEMMGVTLTVMRLDGELARLV
GAPARSVGLTRIPS

Sequences:

>Translated_334_residues
MNRIINDPDLVVEDAVRGYLKAHRDLVRPTTNPRVIRHHLAPQQGKVGVVTGGGSGHEPAFLGYVGDGMIDAVAIGEIFS
SPTAKSFHDAFVAADGGRGVACLYGNYAGDNMNVKLAVKKAASHDLTVKTVVANDDVPSAPKSERDKRRGVAGEILMWKV
GGARAAEGADLDEVIASAQKAIDATRSIGIGLSPCIIPAVGKPNFSIENGMMEVGIGHHGEPGVEVAPVRPAKEMADLML
DHILPDLPFGRGDDLAVLVSGLGATPVMELYILYDRLSEVLEDRGMTVVHPFIGNYFTSLEMMGVTLTVMRLDGELARLV
GAPARSVGLTRIPS
>Mature_334_residues
MNRIINDPDLVVEDAVRGYLKAHRDLVRPTTNPRVIRHHLAPQQGKVGVVTGGGSGHEPAFLGYVGDGMIDAVAIGEIFS
SPTAKSFHDAFVAADGGRGVACLYGNYAGDNMNVKLAVKKAASHDLTVKTVVANDDVPSAPKSERDKRRGVAGEILMWKV
GGARAAEGADLDEVIASAQKAIDATRSIGIGLSPCIIPAVGKPNFSIENGMMEVGIGHHGEPGVEVAPVRPAKEMADLML
DHILPDLPFGRGDDLAVLVSGLGATPVMELYILYDRLSEVLEDRGMTVVHPFIGNYFTSLEMMGVTLTVMRLDGELARLV
GAPARSVGLTRIPS

Specific function: Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaK domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=328, Percent_Identity=32.6219512195122, Blast_Score=173, Evalue=2e-43,
Organism=Escherichia coli, GI87081857, Length=353, Percent_Identity=35.9773371104816, Blast_Score=217, Evalue=8e-58,
Organism=Caenorhabditis elegans, GI17565018, Length=329, Percent_Identity=31.0030395136778, Blast_Score=167, Evalue=6e-42,
Organism=Saccharomyces cerevisiae, GI6321055, Length=313, Percent_Identity=31.3099041533546, Blast_Score=137, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6323570, Length=287, Percent_Identity=30.3135888501742, Blast_Score=119, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR012736 [H]

Pfam domain/function: PF02733 Dak1 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 35330; Mature: 35330

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRIINDPDLVVEDAVRGYLKAHRDLVRPTTNPRVIRHHLAPQQGKVGVVTGGGSGHEPA
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCEEEEECCCCCCCCE
FLGYVGDGMIDAVAIGEIFSSPTAKSFHDAFVAADGGRGVACLYGNYAGDNMNVKLAVKK
EEEECCCCHHHHHHHHHHHCCCCCCCHHHEEEEECCCCEEEEEECCCCCCCCEEEEEEEE
AASHDLTVKTVVANDDVPSAPKSERDKRRGVAGEILMWKVGGARAAEGADLDEVIASAQK
CCCCCCEEEEEEECCCCCCCCCCHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHH
AIDATRSIGIGLSPCIIPAVGKPNFSIENGMMEVGIGHHGEPGVEVAPVRPAKEMADLML
HHHHHHHCCCCCCCCEEECCCCCCCEECCCEEEECCCCCCCCCCEEECCCCHHHHHHHHH
DHILPDLPFGRGDDLAVLVSGLGATPVMELYILYDRLSEVLEDRGMTVVHPFIGNYFTSL
HHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHH
EMMGVTLTVMRLDGELARLVGAPARSVGLTRIPS
HHHCEEEEEEEECHHHHHHHCCCHHHCCCCCCCC
>Mature Secondary Structure
MNRIINDPDLVVEDAVRGYLKAHRDLVRPTTNPRVIRHHLAPQQGKVGVVTGGGSGHEPA
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCEEEEECCCCCCCCE
FLGYVGDGMIDAVAIGEIFSSPTAKSFHDAFVAADGGRGVACLYGNYAGDNMNVKLAVKK
EEEECCCCHHHHHHHHHHHCCCCCCCHHHEEEEECCCCEEEEEECCCCCCCCEEEEEEEE
AASHDLTVKTVVANDDVPSAPKSERDKRRGVAGEILMWKVGGARAAEGADLDEVIASAQK
CCCCCCEEEEEEECCCCCCCCCCHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHH
AIDATRSIGIGLSPCIIPAVGKPNFSIENGMMEVGIGHHGEPGVEVAPVRPAKEMADLML
HHHHHHHCCCCCCCCEEECCCCCCCEECCCEEEECCCCCCCCCCEEECCCCHHHHHHHHH
DHILPDLPFGRGDDLAVLVSGLGATPVMELYILYDRLSEVLEDRGMTVVHPFIGNYFTSL
HHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHH
EMMGVTLTVMRLDGELARLVGAPARSVGLTRIPS
HHHCEEEEEEEECHHHHHHHCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]