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The map label for this gene is rlmH

Identifier: 83592571

GI number: 83592571

Start: 1459019

End: 1459477

Strand: Reverse

Name: rlmH

Synonym: Rru_A1235

Alternate gene names: 83592571

Gene position: 1459477-1459019 (Counterclockwise)

Preceding gene: 83592572

Following gene: 83592570

Centisome position: 33.53

GC content: 70.59

Gene sequence:

>459_bases
ATGAAACTGCTCGTGGCGGCCGTCGGCCGCTGGCGTGGAGGGCCCGAACGGGCCCTCTTCGACCATTATGTCGGCCGGCT
CAAGGGCGGTCTGGCGGTGATCGAGGTTGAGGAACGCCGCCCGCTGCCCGTCGCCGAACGCAAGGCCCGCGAAGCCGAGC
TGCTGCTGGCCCAGCTTCCCCCCGGCGCCTTTGTGGTGGCGCTGGACGAACATGGCGAGGCCTGGGGCAGCGAGCGTCTG
GCCCGGGAGCTTGACCAACGCCGCCTGGAGGCCCGACCGGCCGCGGTTTTCGCCATCGGCGGCGCCGACGGCCATGGCGA
GGCCCTGCTGGCCCGGGCCGATCGCAAGCTGGCCCTGGGGGTGATGACCTGGCCGCACATGCTGGTGCGCGGGCTGATCG
CCGAGCAGCTTTACCGCGCCCAATGCATTTCGGGTGGACACCCTTACCATCGAAGCTGA

Upstream 100 bases:

>100_bases
CAAGACAGCGGACCGGAGGGCGCGAGAGCGGAATGGGCGCTCCGGCAGATCAACGGGTGAGCCCCGCCACCGCCGTCGCC
GCCCTGGTGGTGGCGCGGCC

Downstream 100 bases:

>100_bases
GCGGCGGCGCCCGATCCTCGCCTTTCGTCTTTCGAAGCCGGTGCCAGGACGCTTATATAGGGGACACCCATAGGGGGGCT
GGCCCGCGTGCGGGATCCCC

Product: hypothetical protein

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MKLLVAAVGRWRGGPERALFDHYVGRLKGGLAVIEVEERRPLPVAERKAREAELLLAQLPPGAFVVALDEHGEAWGSERL
ARELDQRRLEARPAAVFAIGGADGHGEALLARADRKLALGVMTWPHMLVRGLIAEQLYRAQCISGGHPYHRS

Sequences:

>Translated_152_residues
MKLLVAAVGRWRGGPERALFDHYVGRLKGGLAVIEVEERRPLPVAERKAREAELLLAQLPPGAFVVALDEHGEAWGSERL
ARELDQRRLEARPAAVFAIGGADGHGEALLARADRKLALGVMTWPHMLVRGLIAEQLYRAQCISGGHPYHRS
>Mature_152_residues
MKLLVAAVGRWRGGPERALFDHYVGRLKGGLAVIEVEERRPLPVAERKAREAELLLAQLPPGAFVVALDEHGEAWGSERL
ARELDQRRLEARPAAVFAIGGADGHGEALLARADRKLALGVMTWPHMLVRGLIAEQLYRAQCISGGHPYHRS

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family

Homologues:

Organism=Escherichia coli, GI1786855, Length=87, Percent_Identity=43.6781609195402, Blast_Score=74, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMH_RHORT (Q2RV09)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_426323.1
- ProteinModelPortal:   Q2RV09
- SMR:   Q2RV09
- STRING:   Q2RV09
- GeneID:   3833733
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A1235
- NMPDR:   fig|1085.1.peg.3131
- eggNOG:   COG1576
- HOGENOM:   HBG622807
- OMA:   ILSGHPY
- PhylomeDB:   Q2RV09
- BioCyc:   RRUB269796:RRU_A1235-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00658
- InterPro:   IPR003742
- PIRSF:   PIRSF004505

Pfam domain/function: PF02590 SPOUT_MTase

EC number: NA

Molecular weight: Translated: 16711; Mature: 16711

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLVAAVGRWRGGPERALFDHYVGRLKGGLAVIEVEERRPLPVAERKAREAELLLAQLP
CCHHEEEHHHCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHEECC
PGAFVVALDEHGEAWGSERLARELDQRRLEARPAAVFAIGGADGHGEALLARADRKLALG
CCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHEECCCCCEEEH
VMTWPHMLVRGLIAEQLYRAQCISGGHPYHRS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKLLVAAVGRWRGGPERALFDHYVGRLKGGLAVIEVEERRPLPVAERKAREAELLLAQLP
CCHHEEEHHHCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHEECC
PGAFVVALDEHGEAWGSERLARELDQRRLEARPAAVFAIGGADGHGEALLARADRKLALG
CCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHEECCCCCEEEH
VMTWPHMLVRGLIAEQLYRAQCISGGHPYHRS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA