Click here to switch to the map view.

The map label for this gene is xerC [H]

Identifier: 83592556

GI number: 83592556

Start: 1439943

End: 1440935

Strand: Reverse

Name: xerC [H]

Synonym: Rru_A1220

Alternate gene names: 83592556

Gene position: 1440935-1439943 (Counterclockwise)

Preceding gene: 83592557

Following gene: 83592554

Centisome position: 33.1

GC content: 70.29

Gene sequence:

>993_bases
ATGGATCGTCCGGATTTACCAGCCGACCCCGCCCCGCACCCCGACGAGGCCGGCGTGGTGCCGGGGCTGTTCCTGCCCTG
CGCTAGCGATCTGCGGCCGTCGCTGGTCGCTTGGCTCGGCTGGCTTCAGGGGGAGCGCCGCGCCAGCCGCCATACCCTGG
ACGCCTATGGCCGCGATCTGGCGGCCTTTCTGACCTTCTTGCGCGATTACCGGGGCGAGGAGCCGGGTCTGGCCACCCTG
GCCTCGCTTGGTCCGGCCGATTTCCGCGCCTATATGGCCGCCCGGCTGACCCAGGGGCTGTCGCGGCCCTCGATGGCCCG
CGCCCTGTCGACTTTACGCAATCTCTTCCGCTGGCTCGACCGCGAGGGCGTTTTGCGCAATGGCGCCATCGCCACCATCC
GCTCACCGCGCCAACCCCAGGCCGTCCCCAAGGCGCTGAGCGAAAGCGAAGCCCTGGACGCCCTGTCGGTGGCCTCGGAC
CTGCAAGACGACCCCTGGCTGGCCAAACGCGATCTCGCGCTGTTCACCTTGCTCTATGGCTGCGGCTTGCGGCTGGGCGA
GGCGCTCGATCTTGATCGCGGCGACCTGCCGAGCGGCGAGGTGATGCGGATCACCGGCAAGGGCCGCAAGGAGCGTCTGG
TGCCGCTGCTGCCGGTGGTGGTCGAGGCGCTGGCCGATTATCTGGCGGCCTGTCCCTTCGCCGGGGGCCCCGATGATCCG
CTGTTCCTGGGCAGTCGCGGCAAGCGGCTTAATCCCGGGGTGGTGCAGCGCCAGATGCGGCGGCTGCGCGGCTTCCTCGG
GCTTCCCGAAACCGCCACCCCCCATGCCTTGCGCCACAGCTTCGCCACCCATCTGCTGGCCCAGGGCGGCGATTTGCGGA
CCATCCAGGAACTGCTCGGCCACGCCTCGCTCTCGACCACCCAGCGCTACACCAAGGTCGATGCCGGCACCCTGGTCGGC
CTGCATGGCGCCACCCACCCCCGCGCCCGCTGA

Upstream 100 bases:

>100_bases
AAGGCACCTTCGAGCCCGAGATGGCGATGGATCTTCTGGTTTTCCTGGCCAAGGTCGCCGAAGCCTGCGTGCGACGATGG
GCCCCCGACACCCTGTGAGC

Downstream 100 bases:

>100_bases
GAAAGCCGCTCCGCCGCACCCCAAGGCGCCGTCTTTACCGCTCCGCCCCCGGACCCAGGCCATGGCGGGCGAGCAGGCGG
CGGAACTGGTGATAGCCCAG

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MDRPDLPADPAPHPDEAGVVPGLFLPCASDLRPSLVAWLGWLQGERRASRHTLDAYGRDLAAFLTFLRDYRGEEPGLATL
ASLGPADFRAYMAARLTQGLSRPSMARALSTLRNLFRWLDREGVLRNGAIATIRSPRQPQAVPKALSESEALDALSVASD
LQDDPWLAKRDLALFTLLYGCGLRLGEALDLDRGDLPSGEVMRITGKGRKERLVPLLPVVVEALADYLAACPFAGGPDDP
LFLGSRGKRLNPGVVQRQMRRLRGFLGLPETATPHALRHSFATHLLAQGGDLRTIQELLGHASLSTTQRYTKVDAGTLVG
LHGATHPRAR

Sequences:

>Translated_330_residues
MDRPDLPADPAPHPDEAGVVPGLFLPCASDLRPSLVAWLGWLQGERRASRHTLDAYGRDLAAFLTFLRDYRGEEPGLATL
ASLGPADFRAYMAARLTQGLSRPSMARALSTLRNLFRWLDREGVLRNGAIATIRSPRQPQAVPKALSESEALDALSVASD
LQDDPWLAKRDLALFTLLYGCGLRLGEALDLDRGDLPSGEVMRITGKGRKERLVPLLPVVVEALADYLAACPFAGGPDDP
LFLGSRGKRLNPGVVQRQMRRLRGFLGLPETATPHALRHSFATHLLAQGGDLRTIQELLGHASLSTTQRYTKVDAGTLVG
LHGATHPRAR
>Mature_330_residues
MDRPDLPADPAPHPDEAGVVPGLFLPCASDLRPSLVAWLGWLQGERRASRHTLDAYGRDLAAFLTFLRDYRGEEPGLATL
ASLGPADFRAYMAARLTQGLSRPSMARALSTLRNLFRWLDREGVLRNGAIATIRSPRQPQAVPKALSESEALDALSVASD
LQDDPWLAKRDLALFTLLYGCGLRLGEALDLDRGDLPSGEVMRITGKGRKERLVPLLPVVVEALADYLAACPFAGGPDDP
LFLGSRGKRLNPGVVQRQMRRLRGFLGLPETATPHALRHSFATHLLAQGGDLRTIQELLGHASLSTTQRYTKVDAGTLVG
LHGATHPRAR

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=304, Percent_Identity=37.5, Blast_Score=174, Evalue=7e-45,
Organism=Escherichia coli, GI1789261, Length=294, Percent_Identity=39.7959183673469, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1790768, Length=157, Percent_Identity=33.1210191082803, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 35864; Mature: 35864

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRPDLPADPAPHPDEAGVVPGLFLPCASDLRPSLVAWLGWLQGERRASRHTLDAYGRDL
CCCCCCCCCCCCCCCCCCCCCHHHHHCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAFLTFLRDYRGEEPGLATLASLGPADFRAYMAARLTQGLSRPSMARALSTLRNLFRWLD
HHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
REGVLRNGAIATIRSPRQPQAVPKALSESEALDALSVASDLQDDPWLAKRDLALFTLLYG
HCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
CGLRLGEALDLDRGDLPSGEVMRITGKGRKERLVPLLPVVVEALADYLAACPFAGGPDDP
HCHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
LFLGSRGKRLNPGVVQRQMRRLRGFLGLPETATPHALRHSFATHLLAQGGDLRTIQELLG
EEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHC
HASLSTTQRYTKVDAGTLVGLHGATHPRAR
CCHHHHHHHHHHCCCCCEEECCCCCCCCCC
>Mature Secondary Structure
MDRPDLPADPAPHPDEAGVVPGLFLPCASDLRPSLVAWLGWLQGERRASRHTLDAYGRDL
CCCCCCCCCCCCCCCCCCCCCHHHHHCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAFLTFLRDYRGEEPGLATLASLGPADFRAYMAARLTQGLSRPSMARALSTLRNLFRWLD
HHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
REGVLRNGAIATIRSPRQPQAVPKALSESEALDALSVASDLQDDPWLAKRDLALFTLLYG
HCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
CGLRLGEALDLDRGDLPSGEVMRITGKGRKERLVPLLPVVVEALADYLAACPFAGGPDDP
HCHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
LFLGSRGKRLNPGVVQRQMRRLRGFLGLPETATPHALRHSFATHLLAQGGDLRTIQELLG
EEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHC
HASLSTTQRYTKVDAGTLVGLHGATHPRAR
CCHHHHHHHHHHCCCCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]