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The map label for this gene is sdhB [H]

Identifier: 83592541

GI number: 83592541

Start: 1422608

End: 1423390

Strand: Direct

Name: sdhB [H]

Synonym: Rru_A1205

Alternate gene names: 83592541

Gene position: 1422608-1423390 (Clockwise)

Preceding gene: 83592540

Following gene: 83592543

Centisome position: 32.68

GC content: 60.41

Gene sequence:

>783_bases
ATGGTTGAATTCGCTCTGCCCCCCAACAGCCGGGTCAAGGAAGGCAAGACCTTCCCCGCGCCGGATGGGGCGAAGCGCCT
AAAGCGCTTCAAGATTTATCGATGGGATCCGGAAGAGGGCGGCAACCCCCGTCTGGATACCTTCCAGATCGATCTCGACG
ACTGCGGCCCGATGGTTCTGGACGCGCTCAACAAGATCAAAAACGAAATCGACCCGACCCTGACCTACCGGCGCTCCTGC
CGCGAGGGCATCTGCGGCTCGTGTTCGATGAATATCGACAGCAATAACTCGCTGGCCTGCCTGAAGCCGATCGCCGAGGT
CGAAGGCGATGTCGAGATCTATCCGCTGCCCCACCTGCCGGTGGTCAAGGATCTGGTTCCCGACCTGACCCATATCTATG
CCCAGTACAACGCCATCGAACCTTGGCTGAAGACCGACAGCCCGCCGCCGCCGGCCAAGGAACGCCTGCAAAGCCCCGAA
GAACGGGCGAGGCTTGATGGCTTGTGGGAATGCATCTTGTGCTTCTGCTGCCAGACCAGCTGTCCGAGCTACTGGTGGAA
CAGCGAACGCTATCTTGGTCCGGCGATTCTGCTTCAGGCGGCGCGCTGGGTGTTTGACAGCCGCGACGAAGCGACCGGCG
AGCGTCTGGACATGCTCGACGATCCGTTCCGTCTGTTCCGTTGCCATACCATCATGAATTGCACGGCGACTTGCCCCAAG
GGTCTCAACCCCGGCAAGGCCATCGCCGATCTCAAGATCAAGATGTTCGAACGCACCGCCTGA

Upstream 100 bases:

>100_bases
TACCGTCCGGTTCACACCTTCACCCTGACCGACGAGATCGACTACATCGAACCCAAGGCGCGCGTGTACTGACGAGCCAA
GCAGGCTGGAGGCATCACAG

Downstream 100 bases:

>100_bases
TCGGCGGACGCAGCGCGCATGAAAACCGGGGGCCGTTCCGCAAGGGGCGGCCCTTTTGGTTTGGGCGACAAGGGGAAGCC
ACGGCCAATCTAGCGCGCTC

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MVEFALPPNSRVKEGKTFPAPDGAKRLKRFKIYRWDPEEGGNPRLDTFQIDLDDCGPMVLDALNKIKNEIDPTLTYRRSC
REGICGSCSMNIDSNNSLACLKPIAEVEGDVEIYPLPHLPVVKDLVPDLTHIYAQYNAIEPWLKTDSPPPPAKERLQSPE
ERARLDGLWECILCFCCQTSCPSYWWNSERYLGPAILLQAARWVFDSRDEATGERLDMLDDPFRLFRCHTIMNCTATCPK
GLNPGKAIADLKIKMFERTA

Sequences:

>Translated_260_residues
MVEFALPPNSRVKEGKTFPAPDGAKRLKRFKIYRWDPEEGGNPRLDTFQIDLDDCGPMVLDALNKIKNEIDPTLTYRRSC
REGICGSCSMNIDSNNSLACLKPIAEVEGDVEIYPLPHLPVVKDLVPDLTHIYAQYNAIEPWLKTDSPPPPAKERLQSPE
ERARLDGLWECILCFCCQTSCPSYWWNSERYLGPAILLQAARWVFDSRDEATGERLDMLDDPFRLFRCHTIMNCTATCPK
GLNPGKAIADLKIKMFERTA
>Mature_260_residues
MVEFALPPNSRVKEGKTFPAPDGAKRLKRFKIYRWDPEEGGNPRLDTFQIDLDDCGPMVLDALNKIKNEIDPTLTYRRSC
REGICGSCSMNIDSNNSLACLKPIAEVEGDVEIYPLPHLPVVKDLVPDLTHIYAQYNAIEPWLKTDSPPPPAKERLQSPE
ERARLDGLWECILCFCCQTSCPSYWWNSERYLGPAILLQAARWVFDSRDEATGERLDMLDDPFRLFRCHTIMNCTATCPK
GLNPGKAIADLKIKMFERTA

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=239, Percent_Identity=63.1799163179916, Blast_Score=325, Evalue=2e-89,
Organism=Escherichia coli, GI1786943, Length=235, Percent_Identity=50.6382978723404, Blast_Score=254, Evalue=4e-69,
Organism=Escherichia coli, GI1790596, Length=226, Percent_Identity=31.4159292035398, Blast_Score=135, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17533915, Length=247, Percent_Identity=57.085020242915, Blast_Score=302, Evalue=9e-83,
Organism=Saccharomyces cerevisiae, GI6322987, Length=229, Percent_Identity=63.7554585152838, Blast_Score=315, Evalue=5e-87,
Organism=Drosophila melanogaster, GI17137106, Length=244, Percent_Identity=58.6065573770492, Blast_Score=317, Evalue=4e-87,
Organism=Drosophila melanogaster, GI24643156, Length=230, Percent_Identity=63.0434782608696, Blast_Score=307, Evalue=4e-84,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29539; Mature: 29539

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEFALPPNSRVKEGKTFPAPDGAKRLKRFKIYRWDPEEGGNPRLDTFQIDLDDCGPMVL
CCEECCCCCCCCCCCCCCCCCCHHHHHHHHEEEEECCCCCCCCCCEEEEEECCCCCHHHH
DALNKIKNEIDPTLTYRRSCREGICGSCSMNIDSNNSLACLKPIAEVEGDVEIYPLPHLP
HHHHHHHHHCCHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHCCCCEEEEECCCCC
VVKDLVPDLTHIYAQYNAIEPWLKTDSPPPPAKERLQSPEERARLDGLWECILCFCCQTS
HHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
CPSYWWNSERYLGPAILLQAARWVFDSRDEATGERLDMLDDPFRLFRCHTIMNCTATCPK
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCC
GLNPGKAIADLKIKMFERTA
CCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MVEFALPPNSRVKEGKTFPAPDGAKRLKRFKIYRWDPEEGGNPRLDTFQIDLDDCGPMVL
CCEECCCCCCCCCCCCCCCCCCHHHHHHHHEEEEECCCCCCCCCCEEEEEECCCCCHHHH
DALNKIKNEIDPTLTYRRSCREGICGSCSMNIDSNNSLACLKPIAEVEGDVEIYPLPHLP
HHHHHHHHHCCHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHCCCCEEEEECCCCC
VVKDLVPDLTHIYAQYNAIEPWLKTDSPPPPAKERLQSPEERARLDGLWECILCFCCQTS
HHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
CPSYWWNSERYLGPAILLQAARWVFDSRDEATGERLDMLDDPFRLFRCHTIMNCTATCPK
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCC
GLNPGKAIADLKIKMFERTA
CCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA