Click here to switch to the map view.

The map label for this gene is asd [H]

Identifier: 83592532

GI number: 83592532

Start: 1412623

End: 1413660

Strand: Direct

Name: asd [H]

Synonym: Rru_A1196

Alternate gene names: 83592532

Gene position: 1412623-1413660 (Clockwise)

Preceding gene: 83592531

Following gene: 83592536

Centisome position: 32.45

GC content: 62.24

Gene sequence:

>1038_bases
ATGGCTTACAGAGCAGGCGGCTATCGGGTGGCGGTGATCGGCGCCACCGGCAATGTCGGGCGCGAAATGCTGTCCACCCT
TGCCGAACGTAAATTTCCAGTCAGCGAAGTGATCGCGCTCGCCTCCTCGCGCTCGGCGGGACGCGAGGTGTCTTTCGGCG
AGGATCAGGTGCTGAAGGTCCGCGACCTTGAGACCTTCGATTTCACCGGGGTCGATATCGCCCTCAGTTCGCCCGGCGCC
AAGGTGTCGGCCACCCATAGCCCGCGCGCCGCCGCCGCCGGCTGCGTGGTGATCGACAACACCAGCCATTTCCGCATGGA
TCGCGACGTGCCGTTGGTGGTGCCCGAGGTCAATCCCCAGGCGATCGCCGGCTATACCAAGCGTCATATCATCGCCAATC
CCAATTGCTCGACCATCCAGATGGTGGTGGCGCTCAAGCCCCTGCACGACGCCTTCGGCATCAAGCGCGTGGTCGTCAGC
ACCTATCAGTCGGTGTCGGGCGCGGGCAAGGATGGCATGGACGAGCTGTTCAACCAGACCAAGGGCATCTACGTCAACCA
GCCGCCCGCCGACTTCCAGCAGAAGTTCACCAAGCAGATCGCCTTCAACGTCATCCCCCATATCGATATTTTCATGGATG
ACGGCGCCACCAAGGAAGAGTGGAAGATGGCGGCCGAGACCTGCAAGATCCTCGATCCGGCGATCAAGGTTCACGCCAAT
TGCGCCCGGGTCCCGGTCTTCGTCGGTCATGCGGAATACGTCAACATCGAGACCGAAAAGCCGATGAGCGAAGAGGCGGC
CCGCCGCGCCCTCAAGGGCGGCGAAGGGGTGATCATCGTCGATCATCGCGCCAATGAAGGCTATGTGACGCCGGCCGAGT
GTTCGGGCGAGGACGCGGTTTATGTTTCGCGCATCCGCAAGGACACCACCGTTGAGAACGGTCTGTCGTTCTGGTGCGTC
TCCGACAATCTGCGCAAGGGCGCCGCGCTCAATGCCGTGCAGATCGCCGAGGTTCTGGCCCGCGATTACCTGAAGTAG

Upstream 100 bases:

>100_bases
GGCGGGGCAGTAGCGCGGCGGCTTCCCTTGATCACTCGGGCCTCAGGGGGTAGCTTTTCCCCCCTCCACGGCCCGAGAAC
TCAAGGGGTTTGAGATAACC

Downstream 100 bases:

>100_bases
GGCCGCCGACCGGGTCCCAAAACGCCCCCTTTCCGCCGTTTCAATCGGGAAGGGGGCGTTTTTTCGCGCTTACCCCGCCA
CGCGGATCTGCGTGACGAAG

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MAYRAGGYRVAVIGATGNVGREMLSTLAERKFPVSEVIALASSRSAGREVSFGEDQVLKVRDLETFDFTGVDIALSSPGA
KVSATHSPRAAAAGCVVIDNTSHFRMDRDVPLVVPEVNPQAIAGYTKRHIIANPNCSTIQMVVALKPLHDAFGIKRVVVS
TYQSVSGAGKDGMDELFNQTKGIYVNQPPADFQQKFTKQIAFNVIPHIDIFMDDGATKEEWKMAAETCKILDPAIKVHAN
CARVPVFVGHAEYVNIETEKPMSEEAARRALKGGEGVIIVDHRANEGYVTPAECSGEDAVYVSRIRKDTTVENGLSFWCV
SDNLRKGAALNAVQIAEVLARDYLK

Sequences:

>Translated_345_residues
MAYRAGGYRVAVIGATGNVGREMLSTLAERKFPVSEVIALASSRSAGREVSFGEDQVLKVRDLETFDFTGVDIALSSPGA
KVSATHSPRAAAAGCVVIDNTSHFRMDRDVPLVVPEVNPQAIAGYTKRHIIANPNCSTIQMVVALKPLHDAFGIKRVVVS
TYQSVSGAGKDGMDELFNQTKGIYVNQPPADFQQKFTKQIAFNVIPHIDIFMDDGATKEEWKMAAETCKILDPAIKVHAN
CARVPVFVGHAEYVNIETEKPMSEEAARRALKGGEGVIIVDHRANEGYVTPAECSGEDAVYVSRIRKDTTVENGLSFWCV
SDNLRKGAALNAVQIAEVLARDYLK
>Mature_344_residues
AYRAGGYRVAVIGATGNVGREMLSTLAERKFPVSEVIALASSRSAGREVSFGEDQVLKVRDLETFDFTGVDIALSSPGAK
VSATHSPRAAAAGCVVIDNTSHFRMDRDVPLVVPEVNPQAIAGYTKRHIIANPNCSTIQMVVALKPLHDAFGIKRVVVST
YQSVSGAGKDGMDELFNQTKGIYVNQPPADFQQKFTKQIAFNVIPHIDIFMDDGATKEEWKMAAETCKILDPAIKVHANC
ARVPVFVGHAEYVNIETEKPMSEEAARRALKGGEGVIIVDHRANEGYVTPAECSGEDAVYVSRIRKDTTVENGLSFWCVS
DNLRKGAALNAVQIAEVLARDYLK

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=339, Percent_Identity=39.5280235988201, Blast_Score=241, Evalue=4e-65,
Organism=Escherichia coli, GI1789841, Length=355, Percent_Identity=27.6056338028169, Blast_Score=93, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320362, Length=397, Percent_Identity=29.7229219143577, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37443; Mature: 37312

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYRAGGYRVAVIGATGNVGREMLSTLAERKFPVSEVIALASSRSAGREVSFGEDQVLKV
CCEECCCEEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEE
RDLETFDFTGVDIALSSPGAKVSATHSPRAAAAGCVVIDNTSHFRMDRDVPLVVPEVNPQ
ECCCEECCCCEEEEECCCCCEEEECCCCCCHHCCEEEEECCCCEEECCCCCEEEECCCCH
AIAGYTKRHIIANPNCSTIQMVVALKPLHDAFGIKRVVVSTYQSVSGAGKDGMDELFNQT
HHHCCCCCEEEECCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHC
KGIYVNQPPADFQQKFTKQIAFNVIPHIDIFMDDGATKEEWKMAAETCKILDPAIKVHAN
CCEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCHHHHEECC
CARVPVFVGHAEYVNIETEKPMSEEAARRALKGGEGVIIVDHRANEGYVTPAECSGEDAV
CEECEEEECCEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCCEECCCCCCCCCCH
YVSRIRKDTTVENGLSFWCVSDNLRKGAALNAVQIAEVLARDYLK
HHHHHHHCCHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AYRAGGYRVAVIGATGNVGREMLSTLAERKFPVSEVIALASSRSAGREVSFGEDQVLKV
CEECCCEEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEE
RDLETFDFTGVDIALSSPGAKVSATHSPRAAAAGCVVIDNTSHFRMDRDVPLVVPEVNPQ
ECCCEECCCCEEEEECCCCCEEEECCCCCCHHCCEEEEECCCCEEECCCCCEEEECCCCH
AIAGYTKRHIIANPNCSTIQMVVALKPLHDAFGIKRVVVSTYQSVSGAGKDGMDELFNQT
HHHCCCCCEEEECCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHC
KGIYVNQPPADFQQKFTKQIAFNVIPHIDIFMDDGATKEEWKMAAETCKILDPAIKVHAN
CCEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCHHHHEECC
CARVPVFVGHAEYVNIETEKPMSEEAARRALKGGEGVIIVDHRANEGYVTPAECSGEDAV
CEECEEEECCEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCCEECCCCCCCCCCH
YVSRIRKDTTVENGLSFWCVSDNLRKGAALNAVQIAEVLARDYLK
HHHHHHHCCHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]