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The map label for this gene is kdpE [H]

Identifier: 83592495

GI number: 83592495

Start: 1375578

End: 1376270

Strand: Direct

Name: kdpE [H]

Synonym: Rru_A1159

Alternate gene names: 83592495

Gene position: 1375578-1376270 (Clockwise)

Preceding gene: 83592494

Following gene: 83592497

Centisome position: 31.6

GC content: 65.95

Gene sequence:

>693_bases
ATGGCCCAGAAGATCCTGGTGGTCGATGACGAACCGCAGATCCGCAAATTCATGCGCATCAGCCTGGGGGCCAATGGCTA
TGAGGTCCTGGAGGCGGAAACCGCCGAACAGGGCGTGATGCTGGCGACGGGGATGGCGCCCGATCTGGTCGTTCTCGATC
TCGGGCTGCCCGATCTTGATGGCCAGGACGCCATCAGCATGATCCGCACGGCCAGCGCCGTGCCGATCATCGTGCTTTCG
GTGCGCTCGGGCGAAACCGATAAGGTCGAGGCCCTCGATCGCGGCGCCAACGATTATGTGGTCAAGCCCTTTGGCATCGG
CGAGTTGATGGCGCGCATCCGCGCCGCCCTGCGCCCGCGCGCCGGTTCGGGCGAGGAGGGGGCGGGCGAGGTTCTGACCA
TCGGCGCCCTGGTGCTCGATTTCGCCCGCCGGGTGGTGACGCGCGGTGGCGACGAGGTGCGGCTGTCGCGCAAGGAATAC
GATCTGCTGCGCCTGCTGGCCGAAAAAGCCGATCACGTGCTGACCCACCGCCAGATCCTGCGCGACATCTGGGGCCCGGC
CCATGTCGAGGATACGGCTTACCTGCGCGTCTACGTCAACCAACTGCGCCAGAAGCTCGAGGCCAACCCGTCGGAACCCC
GGCTGATCGTGACCGAACCCGGGGTGGGCTATCGTTTGAAACGCGGCGAGTAG

Upstream 100 bases:

>100_bases
TCGCCGCCGAGCCCGGCATCAATGATTGCGGAACCTGCATCGTCATCACCTTGCCGCTGCTGGTCGAGCCCGAACTGCTT
GGCGCCGAGGAGAAGGTTTG

Downstream 100 bases:

>100_bases
GGCAAGGGGGCGGCCAAGGCCCCCTTGCCCTCGGTGGATCAGGCGCGGATGCCGGACAGGAAACCCGCGACCTCGCCGCG
CAGGGTCTTGGCTTCGGCGA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MAQKILVVDDEPQIRKFMRISLGANGYEVLEAETAEQGVMLATGMAPDLVVLDLGLPDLDGQDAISMIRTASAVPIIVLS
VRSGETDKVEALDRGANDYVVKPFGIGELMARIRAALRPRAGSGEEGAGEVLTIGALVLDFARRVVTRGGDEVRLSRKEY
DLLRLLAEKADHVLTHRQILRDIWGPAHVEDTAYLRVYVNQLRQKLEANPSEPRLIVTEPGVGYRLKRGE

Sequences:

>Translated_230_residues
MAQKILVVDDEPQIRKFMRISLGANGYEVLEAETAEQGVMLATGMAPDLVVLDLGLPDLDGQDAISMIRTASAVPIIVLS
VRSGETDKVEALDRGANDYVVKPFGIGELMARIRAALRPRAGSGEEGAGEVLTIGALVLDFARRVVTRGGDEVRLSRKEY
DLLRLLAEKADHVLTHRQILRDIWGPAHVEDTAYLRVYVNQLRQKLEANPSEPRLIVTEPGVGYRLKRGE
>Mature_229_residues
AQKILVVDDEPQIRKFMRISLGANGYEVLEAETAEQGVMLATGMAPDLVVLDLGLPDLDGQDAISMIRTASAVPIIVLSV
RSGETDKVEALDRGANDYVVKPFGIGELMARIRAALRPRAGSGEEGAGEVLTIGALVLDFARRVVTRGGDEVRLSRKEYD
LLRLLAEKADHVLTHRQILRDIWGPAHVEDTAYLRVYVNQLRQKLEANPSEPRLIVTEPGVGYRLKRGE

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=49.3273542600897, Blast_Score=215, Evalue=2e-57,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=34.9775784753363, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=36, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1786599, Length=231, Percent_Identity=33.7662337662338, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=38.8646288209607, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=31.8385650224215, Blast_Score=117, Evalue=4e-28,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=33.7719298245614, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=29.3333333333333, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=31.25, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=30.9734513274336, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=29.2576419213974, Blast_Score=91, Evalue=4e-20,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=27.3127753303965, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=28.1385281385281, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1788550, Length=153, Percent_Identity=28.7581699346405, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=26.5217391304348, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25264; Mature: 25132

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQKILVVDDEPQIRKFMRISLGANGYEVLEAETAEQGVMLATGMAPDLVVLDLGLPDLD
CCCEEEEECCCHHHHHHHHHHCCCCCCEEEECHHCCCCEEEEECCCCCEEEEECCCCCCC
GQDAISMIRTASAVPIIVLSVRSGETDKVEALDRGANDYVVKPFGIGELMARIRAALRPR
CHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHCCC
AGSGEEGAGEVLTIGALVLDFARRVVTRGGDEVRLSRKEYDLLRLLAEKADHVLTHRQIL
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHH
RDIWGPAHVEDTAYLRVYVNQLRQKLEANPSEPRLIVTEPGVGYRLKRGE
HHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEECCCC
>Mature Secondary Structure 
AQKILVVDDEPQIRKFMRISLGANGYEVLEAETAEQGVMLATGMAPDLVVLDLGLPDLD
CCEEEEECCCHHHHHHHHHHCCCCCCEEEECHHCCCCEEEEECCCCCEEEEECCCCCCC
GQDAISMIRTASAVPIIVLSVRSGETDKVEALDRGANDYVVKPFGIGELMARIRAALRPR
CHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHCCC
AGSGEEGAGEVLTIGALVLDFARRVVTRGGDEVRLSRKEYDLLRLLAEKADHVLTHRQIL
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHH
RDIWGPAHVEDTAYLRVYVNQLRQKLEANPSEPRLIVTEPGVGYRLKRGE
HHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]