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The map label for this gene is trkH [H]

Identifier: 83592470

GI number: 83592470

Start: 1337522

End: 1339018

Strand: Direct

Name: trkH [H]

Synonym: Rru_A1134

Alternate gene names: 83592470

Gene position: 1337522-1339018 (Clockwise)

Preceding gene: 83592464

Following gene: 83592471

Centisome position: 30.73

GC content: 64.26

Gene sequence:

>1497_bases
ATGAGCCTGAGGGGAAGCCAACTCGGCACCAGCCGGGGCCTGATGCTGGGGGGGATCGATCTCGCCCCGGTGCTGATGGT
CCTTGGGCTGCTGCTGTCGGGCCTCGGGCTCTCGATGCTGGCGCCGGCCTTGGTCGATCTGGTGGTTGAAAACCGCGACT
GGCGGGCGTTCCTCGGCTCTTCGGTGATCACGCTGTTTTGCGGGATGATGCTGACCCTGGCCAATTGGCGGATGCCGCTG
CGCTTCAATATCCGCCAGGGCTTCCTGATGACCGCCCTGGCTTGGCTGACCATGTCGCTGTTTGGCTCCATGCCGTTCAT
GCTGGCGACCACCGGGCTTGATTTCGCCGGGGCGTTTTTTGAGAGCGTTTCGGGATTGACCACCACCGGGGCGACGGTGA
TCAGCGGCCTGGAGCATCAGCCGCCGGGGATCTTGTTCTGGCGCTGCCTGCTGCATTGGATCGGCGGCATCGGCATCATC
GGCATGGCCATCGCCCTGCTGCCGGCGCTGCGCGTCGGCGGCATGCAGCTGTTCCGCACCGAAAGCTCCGATACCAGCGA
AAAGGGCATGAACCGCATCGGCGAATTGGGGCTGGCGATCACCGCCGTCTATCTGACGCTGACCGTGGTCATCGCCTTGG
GCTATATCGCCGTCGGCATGTCGGTTTTCGACGCCATCTGCCACGCCTTCGGCACGGTGTCGACCGGCGGCTTTTCGAAT
TGGGACACCTCGCTTGGCCATCTCGACGCCGCCGGGCTGTGGATGTCGACGGTGGGCATGATGTTGGGCGCCATGCCCTT
CGTGCTCTATGTGCAGGTGGCGCGCGGCCGGCCGATGGATGTGGTGCGCGATCCCCAGGTCCAGGCTTTGACCGGCTTTC
TGGTCGCCTGCTGGTTGGTCATGGCCCTGTGGCAGAGCCTGGAGAACGGCCGGCCCTTCCTTGATGCCCTGACCGCCTCG
GCCTTCAACATCACCTCGGTGGTGACGACGACGGGCTACGCCTCGGAGGATTACACCCTGTGGGGCGGCTTCCCGCAGTT
GTTCTTTTTCATGATCACCTTCGCCGGCGGCTGCACCGGATCGACCTCGGGCGGCATCAAGATGTTCCGCTATCAGGTGG
CCTATAAGGTTCTCAGCGCCAATATCCGCCGGCGCTATATGCCCAATGCGGTCATCGTCTCGACCTATGGCGGGCGGGCG
ATCGACGAGGACGTGGCGGTGTCGGTGGTGCTGTTCTTCTTCGCCACCGGGGCGACGACGGCGATCATCGCCCTGGCGCT
GACCATGGTCGGCCTGGATTGGGTGACGGCCCTGACCGGGACGGCGGCGGCGATCGCCAATGTCGGTCCGGGACTCGGTA
CCATCGTCGGCCCGGCGGGCAATTACGCCACCTTGCCCGATAGCGCGAAATGGCTGCTGTCGCTGGCCATGCTGATGGGG
CGGCTGGAATTCTTCACCCTTCTTGTGCTTTTCAGCCGCGACTTCTGGAAATCCTGA

Upstream 100 bases:

>100_bases
ATCGAGGTGATCGACGGGGGTTCGCCCCCTACGACCTCCGGCGCCGCGCGGCGCGGGGGGCGGTTTTTTCGCGCGGTCGC
AAGCCTGGGAAGGAAACGGA

Downstream 100 bases:

>100_bases
GGAAAGCGCTTTCCCGGCGCTTGCGTGCCGCCGGGAAGGGGGATAGCTTTTTCCCCCGGTCCCGCCAAGAGAGCCCCCGT
CGTCAGGGGCGGCGCGGCCA

Product: cation transporter

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 497

Protein sequence:

>498_residues
MSLRGSQLGTSRGLMLGGIDLAPVLMVLGLLLSGLGLSMLAPALVDLVVENRDWRAFLGSSVITLFCGMMLTLANWRMPL
RFNIRQGFLMTALAWLTMSLFGSMPFMLATTGLDFAGAFFESVSGLTTTGATVISGLEHQPPGILFWRCLLHWIGGIGII
GMAIALLPALRVGGMQLFRTESSDTSEKGMNRIGELGLAITAVYLTLTVVIALGYIAVGMSVFDAICHAFGTVSTGGFSN
WDTSLGHLDAAGLWMSTVGMMLGAMPFVLYVQVARGRPMDVVRDPQVQALTGFLVACWLVMALWQSLENGRPFLDALTAS
AFNITSVVTTTGYASEDYTLWGGFPQLFFFMITFAGGCTGSTSGGIKMFRYQVAYKVLSANIRRRYMPNAVIVSTYGGRA
IDEDVAVSVVLFFFATGATTAIIALALTMVGLDWVTALTGTAAAIANVGPGLGTIVGPAGNYATLPDSAKWLLSLAMLMG
RLEFFTLLVLFSRDFWKS

Sequences:

>Translated_498_residues
MSLRGSQLGTSRGLMLGGIDLAPVLMVLGLLLSGLGLSMLAPALVDLVVENRDWRAFLGSSVITLFCGMMLTLANWRMPL
RFNIRQGFLMTALAWLTMSLFGSMPFMLATTGLDFAGAFFESVSGLTTTGATVISGLEHQPPGILFWRCLLHWIGGIGII
GMAIALLPALRVGGMQLFRTESSDTSEKGMNRIGELGLAITAVYLTLTVVIALGYIAVGMSVFDAICHAFGTVSTGGFSN
WDTSLGHLDAAGLWMSTVGMMLGAMPFVLYVQVARGRPMDVVRDPQVQALTGFLVACWLVMALWQSLENGRPFLDALTAS
AFNITSVVTTTGYASEDYTLWGGFPQLFFFMITFAGGCTGSTSGGIKMFRYQVAYKVLSANIRRRYMPNAVIVSTYGGRA
IDEDVAVSVVLFFFATGATTAIIALALTMVGLDWVTALTGTAAAIANVGPGLGTIVGPAGNYATLPDSAKWLLSLAMLMG
RLEFFTLLVLFSRDFWKS
>Mature_497_residues
SLRGSQLGTSRGLMLGGIDLAPVLMVLGLLLSGLGLSMLAPALVDLVVENRDWRAFLGSSVITLFCGMMLTLANWRMPLR
FNIRQGFLMTALAWLTMSLFGSMPFMLATTGLDFAGAFFESVSGLTTTGATVISGLEHQPPGILFWRCLLHWIGGIGIIG
MAIALLPALRVGGMQLFRTESSDTSEKGMNRIGELGLAITAVYLTLTVVIALGYIAVGMSVFDAICHAFGTVSTGGFSNW
DTSLGHLDAAGLWMSTVGMMLGAMPFVLYVQVARGRPMDVVRDPQVQALTGFLVACWLVMALWQSLENGRPFLDALTASA
FNITSVVTTTGYASEDYTLWGGFPQLFFFMITFAGGCTGSTSGGIKMFRYQVAYKVLSANIRRRYMPNAVIVSTYGGRAI
DEDVAVSVVLFFFATGATTAIIALALTMVGLDWVTALTGTAAAIANVGPGLGTIVGPAGNYATLPDSAKWLLSLAMLMGR
LEFFTLLVLFSRDFWKS

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=481, Percent_Identity=35.7588357588358, Blast_Score=229, Evalue=4e-61,
Organism=Escherichia coli, GI1787626, Length=482, Percent_Identity=31.9502074688797, Blast_Score=214, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 53224; Mature: 53093

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRGSQLGTSRGLMLGGIDLAPVLMVLGLLLSGLGLSMLAPALVDLVVENRDWRAFLGS
CCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHH
SVITLFCGMMLTLANWRMPLRFNIRQGFLMTALAWLTMSLFGSMPFMLATTGLDFAGAFF
HHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHH
ESVSGLTTTGATVISGLEHQPPGILFWRCLLHWIGGIGIIGMAIALLPALRVGGMQLFRT
HHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEC
ESSDTSEKGMNRIGELGLAITAVYLTLTVVIALGYIAVGMSVFDAICHAFGTVSTGGFSN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
WDTSLGHLDAAGLWMSTVGMMLGAMPFVLYVQVARGRPMDVVRDPQVQALTGFLVACWLV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
MALWQSLENGRPFLDALTASAFNITSVVTTTGYASEDYTLWGGFPQLFFFMITFAGGCTG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCEEECCHHHHHHHHHHHHCCCCC
STSGGIKMFRYQVAYKVLSANIRRRYMPNAVIVSTYGGRAIDEDVAVSVVLFFFATGATT
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
AIIALALTMVGLDWVTALTGTAAAIANVGPGLGTIVGPAGNYATLPDSAKWLLSLAMLMG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHH
RLEFFTLLVLFSRDFWKS
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLRGSQLGTSRGLMLGGIDLAPVLMVLGLLLSGLGLSMLAPALVDLVVENRDWRAFLGS
CCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHH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HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]