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The map label for this gene is efp

Identifier: 83592413

GI number: 83592413

Start: 1268670

End: 1269233

Strand: Reverse

Name: efp

Synonym: Rru_A1077

Alternate gene names: 83592413

Gene position: 1269233-1268670 (Counterclockwise)

Preceding gene: 83592415

Following gene: 83592412

Centisome position: 29.16

GC content: 58.51

Gene sequence:

>564_bases
ATGAAAATGCAAGCCAACCAGATCCGGCCTGGCCAGGTGCTGGAACACCAGGGTAAGCGCTGGACCGTCTTGAAGATCCA
GCTCATCCAGCCAGGTAAGGGTGGCGCCTTTATCGCGGTCGAGATGCGCGATGTCGACAGCGGCAACAAAACCAACGAAC
GCTGGCGGACCGCCGATACGGTGGAACGCCTCGAAGTCCGTGAAATCGACTGCCAGTATCTGTTCAAGGACGATACGGGC
TACACCTTCATGGACAAGGAAACCTTCGAGCAGTTCTCGATGGCCGCCGACGCCCTGGGTGAACAGGCCGGCTTCCTTCA
GGAAAGCATGGAGGTCACCGTCGATTGCATCGAAGGATCGCCCGTTTCGGTCAACCTGCCCAGTCAGGTGATCTTGCAGG
TGGTTGAAGCCGATGCGGTGGTGAAGGGGCAGACCGCCTCGTCCTCCTACAAGCCCGGCCTGCTGGAAAACGGCATGAAG
GTCATGATCCCGCCGTTTATCGAAGCCGGTACCCGGATCGTGGTCAGCACCGTCGATTGCAGCTATATCGAACGCGCGAA
GTAA

Upstream 100 bases:

>100_bases
GACTCCTGAAAGGGCTGGAAGGCCAGTTGCGCCCTGAGGGGAAGCCTGATAGGGTCCGCCCCTTCCGAAACGCAAGAGAT
TTGTTCGGGACTATCCCCAC

Downstream 100 bases:

>100_bases
CGCCGCCCGTTCGCGACCACCGAAGACCGGCCGCGCCGACGCGCGTTGGCCGGTTCTTTCCTTTTTGCGCCCTTTGCGGC
GCGTGACCGTTTCGCGCCCC

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MKMQANQIRPGQVLEHQGKRWTVLKIQLIQPGKGGAFIAVEMRDVDSGNKTNERWRTADTVERLEVREIDCQYLFKDDTG
YTFMDKETFEQFSMAADALGEQAGFLQESMEVTVDCIEGSPVSVNLPSQVILQVVEADAVVKGQTASSSYKPGLLENGMK
VMIPPFIEAGTRIVVSTVDCSYIERAK

Sequences:

>Translated_187_residues
MKMQANQIRPGQVLEHQGKRWTVLKIQLIQPGKGGAFIAVEMRDVDSGNKTNERWRTADTVERLEVREIDCQYLFKDDTG
YTFMDKETFEQFSMAADALGEQAGFLQESMEVTVDCIEGSPVSVNLPSQVILQVVEADAVVKGQTASSSYKPGLLENGMK
VMIPPFIEAGTRIVVSTVDCSYIERAK
>Mature_187_residues
MKMQANQIRPGQVLEHQGKRWTVLKIQLIQPGKGGAFIAVEMRDVDSGNKTNERWRTADTVERLEVREIDCQYLFKDDTG
YTFMDKETFEQFSMAADALGEQAGFLQESMEVTVDCIEGSPVSVNLPSQVILQVVEADAVVKGQTASSSYKPGLLENGMK
VMIPPFIEAGTRIVVSTVDCSYIERAK

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=183, Percent_Identity=33.879781420765, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI87082061, Length=189, Percent_Identity=31.2169312169312, Blast_Score=93, Evalue=9e-21,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_RHORT (Q2RVG7)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_426165.1
- ProteinModelPortal:   Q2RVG7
- SMR:   Q2RVG7
- STRING:   Q2RVG7
- GeneID:   3833538
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A1077
- NMPDR:   fig|1085.1.peg.3294
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- PhylomeDB:   Q2RVG7
- ProtClustDB:   PRK00529
- BioCyc:   RRUB269796:RRU_A1077-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20799; Mature: 20799

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMQANQIRPGQVLEHQGKRWTVLKIQLIQPGKGGAFIAVEMRDVDSGNKTNERWRTADT
CCCCCCCCCCCHHHHCCCCEEEEEEEEEECCCCCCEEEEEEEEECCCCCCCCCHHCCHHH
VERLEVREIDCQYLFKDDTGYTFMDKETFEQFSMAADALGEQAGFLQESMEVTVDCIEGS
HHHHHHEECCEEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCC
PVSVNLPSQVILQVVEADAVVKGQTASSSYKPGLLENGMKVMIPPFIEAGTRIVVSTVDC
CEEEECCHHHHHHHHHHCCEEECCCCCCCCCCCHHHCCCEEEECCCCCCCCEEEEEECCC
SYIERAK
CHHHCCC
>Mature Secondary Structure
MKMQANQIRPGQVLEHQGKRWTVLKIQLIQPGKGGAFIAVEMRDVDSGNKTNERWRTADT
CCCCCCCCCCCHHHHCCCCEEEEEEEEEECCCCCCEEEEEEEEECCCCCCCCCHHCCHHH
VERLEVREIDCQYLFKDDTGYTFMDKETFEQFSMAADALGEQAGFLQESMEVTVDCIEGS
HHHHHHEECCEEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCC
PVSVNLPSQVILQVVEADAVVKGQTASSSYKPGLLENGMKVMIPPFIEAGTRIVVSTVDC
CEEEECCHHHHHHHHHHCCEEECCCCCCCCCCCHHHCCCEEEECCCCCCCCEEEEEECCC
SYIERAK
CHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA