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The map label for this gene is mraY

Identifier: 83592289

GI number: 83592289

Start: 1137369

End: 1138451

Strand: Reverse

Name: mraY

Synonym: Rru_A0953

Alternate gene names: 83592289

Gene position: 1138451-1137369 (Counterclockwise)

Preceding gene: 83592290

Following gene: 83592288

Centisome position: 26.15

GC content: 63.71

Gene sequence:

>1083_bases
ATGCTGTACTTCCTGTCCGAACTCACCGCGCAAGTGAGCGCGCTCAACGTCTTCCGGTACCTGACCTTCCGGACGGGCGG
CGCGGTGATGACGGCTATGCTCGTCGCCTTCGTCTTTGGCCCCGGCATCATCGAGTGGCTCAAACGCAAGCAAGGCGAAG
GCCAGCCGATCCGCAGCGACGGACCGGAAAGCCACCTGACCAAGAAGGGCACGCCGACGATGGGCGGCATCATGATCCTT
CTGGGCGTCGGCGTCGCCACCTTGCTGTGGGCCGATCTGTCAAAGGGCTATGTCTGGGCGGTCTTGCTGCTCACCCTGGG
CTATGGGGCCATCGGCTTCGCCGATGACTATCTGAAGCTGACCAAGCGCAACACCAAAGGTCTGTCGGGCCGGCTCAAGC
TGGTCGCCCAGGTCGGCATGGCGGTGATCGCCGGGCTGTGGATCATGCTGCTCGGCCAGGGCGATCAGGCGAGCAGCCTC
GCCCTGCCGTTCTTCAAGGATCTGACCTTCAATCTCGGCTGGTTCTACCTGCCCTTCGCCGCCTTCGTCATGGTCGGCGC
CTCCAACGCCGTCAATCTGACCGACGGCCTGGACGGGTTGGCGATCGTGCCGGTGATGATCGCCGCCGGGGTGTTCATGC
TGATCGCCTATCTGGTCGGCAACATCATCTTTTCGAACTATCTGCAGATCCAGCATGTGCCGGGCACCGGCGAGCTGGCG
GTGTTCTGCGGGGCGATCGTCGGCGCCGCCGTCGGCTTCCTGTGGTTCAACGCCCCGCCGGCCATGGTGTTCATGGGCGA
TACCGGCTCGCTGGCCCTGGGCGGAGCCCTGGGCGCCGTCTCGGTGGTGACCAAGCATGAGATCGTGCTGGCCATCGTTG
GCGGGCTGTTCGTTCTGGAAACCGTTTCGGTGATCGTCCAGGTCGCCTCGTTCAAGCTGACGGGCAAGCGGGTCTTCCGC
ATGGCGCCGCTGCACCATCATTTCGAAAAGAAGGGCTGGGCCGAGCCCACGGTGGTGATCCGGTTCTGGATCATCGCCAT
GATCCTGGCCATCGTCGGCCTTTCCACCTTGAAGCTGCGTTAG

Upstream 100 bases:

>100_bases
CGTCACGGCCCTGCTGGCTCTCGATCGCCGCGCGGAGGCGGGCCTTTCGGCCGCCGACACGCCCTGATTAACCCCCTGCT
GGGAAGCGGAACACCAGGGA

Downstream 100 bases:

>100_bases
GAGAAAAGGGGTGGCGAAGCTAATCCCCCTTTACCAGTACGCCGGACAGGACCTGGGCATCATGGGCCTGGGCAAATCGG
GAATGGCCACGGCGCGGGCG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MLYFLSELTAQVSALNVFRYLTFRTGGAVMTAMLVAFVFGPGIIEWLKRKQGEGQPIRSDGPESHLTKKGTPTMGGIMIL
LGVGVATLLWADLSKGYVWAVLLLTLGYGAIGFADDYLKLTKRNTKGLSGRLKLVAQVGMAVIAGLWIMLLGQGDQASSL
ALPFFKDLTFNLGWFYLPFAAFVMVGASNAVNLTDGLDGLAIVPVMIAAGVFMLIAYLVGNIIFSNYLQIQHVPGTGELA
VFCGAIVGAAVGFLWFNAPPAMVFMGDTGSLALGGALGAVSVVTKHEIVLAIVGGLFVLETVSVIVQVASFKLTGKRVFR
MAPLHHHFEKKGWAEPTVVIRFWIIAMILAIVGLSTLKLR

Sequences:

>Translated_360_residues
MLYFLSELTAQVSALNVFRYLTFRTGGAVMTAMLVAFVFGPGIIEWLKRKQGEGQPIRSDGPESHLTKKGTPTMGGIMIL
LGVGVATLLWADLSKGYVWAVLLLTLGYGAIGFADDYLKLTKRNTKGLSGRLKLVAQVGMAVIAGLWIMLLGQGDQASSL
ALPFFKDLTFNLGWFYLPFAAFVMVGASNAVNLTDGLDGLAIVPVMIAAGVFMLIAYLVGNIIFSNYLQIQHVPGTGELA
VFCGAIVGAAVGFLWFNAPPAMVFMGDTGSLALGGALGAVSVVTKHEIVLAIVGGLFVLETVSVIVQVASFKLTGKRVFR
MAPLHHHFEKKGWAEPTVVIRFWIIAMILAIVGLSTLKLR
>Mature_360_residues
MLYFLSELTAQVSALNVFRYLTFRTGGAVMTAMLVAFVFGPGIIEWLKRKQGEGQPIRSDGPESHLTKKGTPTMGGIMIL
LGVGVATLLWADLSKGYVWAVLLLTLGYGAIGFADDYLKLTKRNTKGLSGRLKLVAQVGMAVIAGLWIMLLGQGDQASSL
ALPFFKDLTFNLGWFYLPFAAFVMVGASNAVNLTDGLDGLAIVPVMIAAGVFMLIAYLVGNIIFSNYLQIQHVPGTGELA
VFCGAIVGAAVGFLWFNAPPAMVFMGDTGSLALGGALGAVSVVTKHEIVLAIVGGLFVLETVSVIVQVASFKLTGKRVFR
MAPLHHHFEKKGWAEPTVVIRFWIIAMILAIVGLSTLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=361, Percent_Identity=53.4626038781163, Blast_Score=367, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_RHORT (Q2RVU1)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_426041.1
- STRING:   Q2RVU1
- GeneID:   3833626
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A0953
- NMPDR:   fig|1085.1.peg.3419
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- PhylomeDB:   Q2RVU1
- ProtClustDB:   PRK00108
- BioCyc:   RRUB269796:RRU_A0953-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 38514; Mature: 38514

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xdcb59d4)-; HASH(0xc7b1ff4)-; HASH(0xe712248)-; HASH(0xe6d1ac0)-; HASH(0xe34f874)-; HASH(0xe6b26cc)-; HASH(0xe6b2648)-; HASH(0xccccdcc)-; HASH(0xe6d1b50)-; HASH(0xe709748)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYFLSELTAQVSALNVFRYLTFRTGGAVMTAMLVAFVFGPGIIEWLKRKQGEGQPIRSD
CEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCC
GPESHLTKKGTPTMGGIMILLGVGVATLLWADLSKGYVWAVLLLTLGYGAIGFADDYLKL
CCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHH
TKRNTKGLSGRLKLVAQVGMAVIAGLWIMLLGQGDQASSLALPFFKDLTFNLGWFYLPFA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCHHHHHHH
AFVMVGASNAVNLTDGLDGLAIVPVMIAAGVFMLIAYLVGNIIFSNYLQIQHVPGTGELA
HHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHH
VFCGAIVGAAVGFLWFNAPPAMVFMGDTGSLALGGALGAVSVVTKHEIVLAIVGGLFVLE
HHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVSVIVQVASFKLTGKRVFRMAPLHHHFEKKGWAEPTVVIRFWIIAMILAIVGLSTLKLR
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHCCH
>Mature Secondary Structure
MLYFLSELTAQVSALNVFRYLTFRTGGAVMTAMLVAFVFGPGIIEWLKRKQGEGQPIRSD
CEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCC
GPESHLTKKGTPTMGGIMILLGVGVATLLWADLSKGYVWAVLLLTLGYGAIGFADDYLKL
CCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHH
TKRNTKGLSGRLKLVAQVGMAVIAGLWIMLLGQGDQASSLALPFFKDLTFNLGWFYLPFA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCHHHHHHH
AFVMVGASNAVNLTDGLDGLAIVPVMIAAGVFMLIAYLVGNIIFSNYLQIQHVPGTGELA
HHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHH
VFCGAIVGAAVGFLWFNAPPAMVFMGDTGSLALGGALGAVSVVTKHEIVLAIVGGLFVLE
HHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVSVIVQVASFKLTGKRVFRMAPLHHHFEKKGWAEPTVVIRFWIIAMILAIVGLSTLKLR
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA