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The map label for this gene is yiaY [H]

Identifier: 83592266

GI number: 83592266

Start: 1106021

End: 1107172

Strand: Reverse

Name: yiaY [H]

Synonym: Rru_A0930

Alternate gene names: 83592266

Gene position: 1107172-1106021 (Counterclockwise)

Preceding gene: 83592267

Following gene: 83592264

Centisome position: 25.44

GC content: 65.89

Gene sequence:

>1152_bases
ATGACTCAGACCGCTTTTTTCATCCCCTCGATCAACCTCATGGGGGCGGGCTGCTTGGCCACCGCCGTCAACACCATCAA
TGAGCGCGGCTTCAAGCGCGCCCTGATCGTCACCGACGCGGTGCTTGAAAAGCTGGGCGTCGCCGGCAAGGTGACCGAGC
TGCTTGATGACCATGGCGTGGAAAGCATCGTTTTCGGCGGCGCCCAGCCCAATCCGACGGTGTCGAATGTCGAGGCGGGT
CTGGCGATCTTGCGCGAGGCCGAATGCGATTGCGTGATCTCGCTGGGCGGCGGCTCGCCCCATGACTGCGCCAAGGGCAT
CGCGCTGTGCGCCACCAACGGCGGGGTCATCGGTGATTACGAGGGCGTCGATAAATCGGCCCATCCGCAATTGCCGCTGA
TCGCCATCAACACCACGGCCGGCACCGCCAGCGAAATGACGCGGTTTTGTATCATCACCGACGAAAGCCGTCTGGTGAAG
ATGGCGATCGTCGACCGCCACGTCACGCCGATCATGTCGGTCAATGACCCCGAACTGATGATCGGCAAGCCCGCCGCCCT
GACCGCCGCCACCGGCATGGACGCCCTGACCCACGCCATCGAAGCCTATGTCTCGATCGCCGCCACGCCGATCACCGACG
CCTGCGCCCTGAAGGCGGTGTCGATCATCGCCCGCACCCTGCGCCGGGCGGTGGCCGATGGCGCCGATATCAAGGCCCGC
GAGGCCATGTCCTATGCCCAGTTCCTGGCCGGCATGGCCTTCAACAACGCCTCCCTCGGCTTCGTTCACGCCATGGCCCA
CCAGTTGGGCGGCTTTTATGACCTGCCCCATGGCGTGTGCAACGCCGTGCTGTTGCCCCATGTCGCCGCCTTCAACGCCA
GCGTTGCCGGGGCCCGCCTCAAGGATGTCGCCGAGGCGATGGGCGTCGACATCGCCAATCTGTCCGACGATCAGGGGGCG
GAGGCCTGCATCGCCGCCATCCGCACCCTAGCCGCCGATATCGGCATTCCCGCCGGCCTTACGGAACTTGGCGTCAAGGA
CGGCGACGTGCCGACCCTGGCGATCAACGCCCTGAAAGACGCCTGCGGCCTGACCAACCCGCGCCCGGCGACCCAGGCCG
AAATCGAGGCGATCTTCCGCGCCGCCGCCTGA

Upstream 100 bases:

>100_bases
AGAACCTGCTGGTCAGCTACGACCCCAAAGCCATGGGGTTCTTTTAAGCGATCCGGGACGCTCCCCTTCGCCCATTCTTC
CGAGAAAAGGACGAACCATC

Downstream 100 bases:

>100_bases
CCTTTTCGATCCGATCCCCTCAACCTGCCCCGGGGTGCCTCCTGCCCCGGGGATTTTTTTTAGCCCGTTTTTCAACGAGC
CGCCAAAGGCTTAAAAAAAA

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MTQTAFFIPSINLMGAGCLATAVNTINERGFKRALIVTDAVLEKLGVAGKVTELLDDHGVESIVFGGAQPNPTVSNVEAG
LAILREAECDCVISLGGGSPHDCAKGIALCATNGGVIGDYEGVDKSAHPQLPLIAINTTAGTASEMTRFCIITDESRLVK
MAIVDRHVTPIMSVNDPELMIGKPAALTAATGMDALTHAIEAYVSIAATPITDACALKAVSIIARTLRRAVADGADIKAR
EAMSYAQFLAGMAFNNASLGFVHAMAHQLGGFYDLPHGVCNAVLLPHVAAFNASVAGARLKDVAEAMGVDIANLSDDQGA
EACIAAIRTLAADIGIPAGLTELGVKDGDVPTLAINALKDACGLTNPRPATQAEIEAIFRAAA

Sequences:

>Translated_383_residues
MTQTAFFIPSINLMGAGCLATAVNTINERGFKRALIVTDAVLEKLGVAGKVTELLDDHGVESIVFGGAQPNPTVSNVEAG
LAILREAECDCVISLGGGSPHDCAKGIALCATNGGVIGDYEGVDKSAHPQLPLIAINTTAGTASEMTRFCIITDESRLVK
MAIVDRHVTPIMSVNDPELMIGKPAALTAATGMDALTHAIEAYVSIAATPITDACALKAVSIIARTLRRAVADGADIKAR
EAMSYAQFLAGMAFNNASLGFVHAMAHQLGGFYDLPHGVCNAVLLPHVAAFNASVAGARLKDVAEAMGVDIANLSDDQGA
EACIAAIRTLAADIGIPAGLTELGVKDGDVPTLAINALKDACGLTNPRPATQAEIEAIFRAAA
>Mature_382_residues
TQTAFFIPSINLMGAGCLATAVNTINERGFKRALIVTDAVLEKLGVAGKVTELLDDHGVESIVFGGAQPNPTVSNVEAGL
AILREAECDCVISLGGGSPHDCAKGIALCATNGGVIGDYEGVDKSAHPQLPLIAINTTAGTASEMTRFCIITDESRLVKM
AIVDRHVTPIMSVNDPELMIGKPAALTAATGMDALTHAIEAYVSIAATPITDACALKAVSIIARTLRRAVADGADIKARE
AMSYAQFLAGMAFNNASLGFVHAMAHQLGGFYDLPHGVCNAVLLPHVAAFNASVAGARLKDVAEAMGVDIANLSDDQGAE
ACIAAIRTLAADIGIPAGLTELGVKDGDVPTLAINALKDACGLTNPRPATQAEIEAIFRAAA

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=397, Percent_Identity=26.9521410579345, Blast_Score=124, Evalue=1e-28,
Organism=Escherichia coli, GI48994951, Length=382, Percent_Identity=69.6335078534031, Blast_Score=543, Evalue=1e-156,
Organism=Escherichia coli, GI1789163, Length=384, Percent_Identity=41.9270833333333, Blast_Score=304, Evalue=6e-84,
Organism=Escherichia coli, GI87082107, Length=377, Percent_Identity=37.9310344827586, Blast_Score=232, Evalue=2e-62,
Organism=Escherichia coli, GI1787493, Length=403, Percent_Identity=33.2506203473945, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI1789386, Length=361, Percent_Identity=25.7617728531856, Blast_Score=98, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17537053, Length=365, Percent_Identity=27.6712328767123, Blast_Score=125, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6321181, Length=381, Percent_Identity=53.2808398950131, Blast_Score=403, Evalue=1e-113,
Organism=Drosophila melanogaster, GI24657991, Length=408, Percent_Identity=24.0196078431373, Blast_Score=102, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 39369; Mature: 39237

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTAFFIPSINLMGAGCLATAVNTINERGFKRALIVTDAVLEKLGVAGKVTELLDDHGV
CCCCEEECCCCHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
ESIVFGGAQPNPTVSNVEAGLAILREAECDCVISLGGGSPHDCAKGIALCATNGGVIGDY
CEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHCCEEEEECCCCEECCC
EGVDKSAHPQLPLIAINTTAGTASEMTRFCIITDESRLVKMAIVDRHVTPIMSVNDPELM
CCCCCCCCCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEHHHHHHCCCCEEECCCCCEE
IGKPAALTAATGMDALTHAIEAYVSIAATPITDACALKAVSIIARTLRRAVADGADIKAR
ECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
EAMSYAQFLAGMAFNNASLGFVHAMAHQLGGFYDLPHGVCNAVLLPHVAAFNASVAGARL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHH
KDVAEAMGVDIANLSDDQGAEACIAAIRTLAADIGIPAGLTELGVKDGDVPTLAINALKD
HHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHH
ACGLTNPRPATQAEIEAIFRAAA
HHCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TQTAFFIPSINLMGAGCLATAVNTINERGFKRALIVTDAVLEKLGVAGKVTELLDDHGV
CCCEEECCCCHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
ESIVFGGAQPNPTVSNVEAGLAILREAECDCVISLGGGSPHDCAKGIALCATNGGVIGDY
CEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHCCEEEEECCCCEECCC
EGVDKSAHPQLPLIAINTTAGTASEMTRFCIITDESRLVKMAIVDRHVTPIMSVNDPELM
CCCCCCCCCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEHHHHHHCCCCEEECCCCCEE
IGKPAALTAATGMDALTHAIEAYVSIAATPITDACALKAVSIIARTLRRAVADGADIKAR
ECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
EAMSYAQFLAGMAFNNASLGFVHAMAHQLGGFYDLPHGVCNAVLLPHVAAFNASVAGARL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHH
KDVAEAMGVDIANLSDDQGAEACIAAIRTLAADIGIPAGLTELGVKDGDVPTLAINALKD
HHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHH
ACGLTNPRPATQAEIEAIFRAAA
HHCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]