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The map label for this gene is paaK [H]

Identifier: 83592129

GI number: 83592129

Start: 942837

End: 944213

Strand: Direct

Name: paaK [H]

Synonym: Rru_A0790

Alternate gene names: 83592129

Gene position: 942837-944213 (Clockwise)

Preceding gene: 83592128

Following gene: 83592130

Centisome position: 21.66

GC content: 68.19

Gene sequence:

>1377_bases
ATGTCCACAGCCCACGCCCCCGTCCTCGCGCCGAAGGCGCCGTCCCTGGCCTCCGAGCGCCGCTATTGGGCTCCCGAGAT
CGAAACCCGCTCGCGGGCCGAATGGGATGCCCAAAGCCTGCGTCTTCTCCAGGCCCACCTGCGCTATGCCTATGGCAACG
CCCCCTATTATCGGGCGCGCTTCGATGCCGCCCGCGTCCATCCCGATGATGTGCGCAGCCTTGATGACCTGCGGCGCTTC
CCGTTGCTTGACAAGGGCGTGTTGCGCGCCCGCCAGCAAGCGGTGCCGTTGCTCGGCGATCTGGCCGCCGTTCCCGAAGA
CGAGGTGGTCTATGTCTCGGCCTCTTCGGGGTCGACCGGCGTGCCGACGCTTTCGCCCTTCACCGCCGGGGATTTCGACG
ACTGGATCGATTTCGAGGCCCGCTTGTTCTGGGCTTCGGGCCTGCGTCCGAGCGATCGCTACGCCCATTCCTTGAACTTC
TCGCTGTTCGTCGGCGGCCCCTGCGTGCTTGGCGCCCAGAAGCTGGGGGCGCTGTCGATCCACGCCGGAACCGTGCCCTC
GGATCGGCTGCTCGCCATCCTCCGCCAGTTCCAGGCGACGGCGATGTGGACGACGCCGTCCTATGCCTGGTACCTGGGCG
AAACCGCCGCGAAGGAGGGGATCGATCCCCGACGCGATCTGGCGGTGCGGCGGATCTTCGTCGCCGGCGAGCCCGGCGGC
TCGATCCCCGAGACCCGCGCCCGCATCGAGGCGCTATGGGGGGCGCGGGTTTACGACTATTACGGGCTGTCCGACATCTT
CGGCGCCTGCGCGGGCATGTGCGAGGAGCGCCAGGGCCTGCATTGGGCCGAGGATCATATCCTGGTCGAGGTGCTCGATC
CGCTGACCGGCGAGCCGGTGGCCGAGGGCGAGCGCGGCGAACTGGTGCTGACCACCCTGCGCAAGCGGGCGCGGCCGCTG
ATCCGCTTCCGTGTGGGCGATATCGTGTCGTTCACCAGTGAACCCTGCGCCTGCGGTCGGACCTCGAAGCGGTTGCTCGG
CGTCCACGGCCGGGTCGATGACATGCTGATCATTCGTGGCGTCAACATCTTCCCCAGCGATATCGAGGCCATCGTTCGCA
AGGACCATGACTTCACCGGCGAATACCGTCTGGTGGTCGAGCGCGTCGACCACCTCGATGCCTTGAGCGTCGAAGTCGAA
CATCGGGCCGGCCTCAATACCCCGCCCGAAGCTCTGGCGGCGCGGCTGCGCGGCCAGATCAAGGCGGTGACCGGGGTGGG
GGCGCGGGTGGTCGTTCTCGCCCCCGACAGCCTGCCGCGCGCCACCCATAAGGCCAAGCGCATCGACGACCGCCGTACCG
GGGTGTGGACGGCCTGA

Upstream 100 bases:

>100_bases
TCGTTCAGGCCGCCGGCGACCGCTTGGCCACTCGCCTCAACAAGCGGGTGGTCCGCCAAGGTCCGCGTCTTTAGACCCCC
CCATTTTCGGGAGCCCCGCC

Downstream 100 bases:

>100_bases
GCCCGGCCATTCCCGTTTCTCCCTAAAAAACCTTTGGAGAAAAAGCCATGAAGCCGTTTTTCAGGGGCGCCCTGGTGGCG
CTCGCCCTTGCCGCGGGGGG

Product: phenylacetate--CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MSTAHAPVLAPKAPSLASERRYWAPEIETRSRAEWDAQSLRLLQAHLRYAYGNAPYYRARFDAARVHPDDVRSLDDLRRF
PLLDKGVLRARQQAVPLLGDLAAVPEDEVVYVSASSGSTGVPTLSPFTAGDFDDWIDFEARLFWASGLRPSDRYAHSLNF
SLFVGGPCVLGAQKLGALSIHAGTVPSDRLLAILRQFQATAMWTTPSYAWYLGETAAKEGIDPRRDLAVRRIFVAGEPGG
SIPETRARIEALWGARVYDYYGLSDIFGACAGMCEERQGLHWAEDHILVEVLDPLTGEPVAEGERGELVLTTLRKRARPL
IRFRVGDIVSFTSEPCACGRTSKRLLGVHGRVDDMLIIRGVNIFPSDIEAIVRKDHDFTGEYRLVVERVDHLDALSVEVE
HRAGLNTPPEALAARLRGQIKAVTGVGARVVVLAPDSLPRATHKAKRIDDRRTGVWTA

Sequences:

>Translated_458_residues
MSTAHAPVLAPKAPSLASERRYWAPEIETRSRAEWDAQSLRLLQAHLRYAYGNAPYYRARFDAARVHPDDVRSLDDLRRF
PLLDKGVLRARQQAVPLLGDLAAVPEDEVVYVSASSGSTGVPTLSPFTAGDFDDWIDFEARLFWASGLRPSDRYAHSLNF
SLFVGGPCVLGAQKLGALSIHAGTVPSDRLLAILRQFQATAMWTTPSYAWYLGETAAKEGIDPRRDLAVRRIFVAGEPGG
SIPETRARIEALWGARVYDYYGLSDIFGACAGMCEERQGLHWAEDHILVEVLDPLTGEPVAEGERGELVLTTLRKRARPL
IRFRVGDIVSFTSEPCACGRTSKRLLGVHGRVDDMLIIRGVNIFPSDIEAIVRKDHDFTGEYRLVVERVDHLDALSVEVE
HRAGLNTPPEALAARLRGQIKAVTGVGARVVVLAPDSLPRATHKAKRIDDRRTGVWTA
>Mature_457_residues
STAHAPVLAPKAPSLASERRYWAPEIETRSRAEWDAQSLRLLQAHLRYAYGNAPYYRARFDAARVHPDDVRSLDDLRRFP
LLDKGVLRARQQAVPLLGDLAAVPEDEVVYVSASSGSTGVPTLSPFTAGDFDDWIDFEARLFWASGLRPSDRYAHSLNFS
LFVGGPCVLGAQKLGALSIHAGTVPSDRLLAILRQFQATAMWTTPSYAWYLGETAAKEGIDPRRDLAVRRIFVAGEPGGS
IPETRARIEALWGARVYDYYGLSDIFGACAGMCEERQGLHWAEDHILVEVLDPLTGEPVAEGERGELVLTTLRKRARPLI
RFRVGDIVSFTSEPCACGRTSKRLLGVHGRVDDMLIIRGVNIFPSDIEAIVRKDHDFTGEYRLVVERVDHLDALSVEVEH
RAGLNTPPEALAARLRGQIKAVTGVGARVVVLAPDSLPRATHKAKRIDDRRTGVWTA

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=436, Percent_Identity=38.0733944954128, Blast_Score=251, Evalue=6e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 50590; Mature: 50459

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAHAPVLAPKAPSLASERRYWAPEIETRSRAEWDAQSLRLLQAHLRYAYGNAPYYRAR
CCCCCCCEECCCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEE
FDAARVHPDDVRSLDDLRRFPLLDKGVLRARQQAVPLLGDLAAVPEDEVVYVSASSGSTG
CCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHCCCCCCEEEEECCCCCCC
VPTLSPFTAGDFDDWIDFEARLFWASGLRPSDRYAHSLNFSLFVGGPCVLGAQKLGALSI
CCCCCCCCCCCCHHHHCCEEEEEEECCCCCCHHHHHCCCEEEEECCCEEECHHHCCEEEE
HAGTVPSDRLLAILRQFQATAMWTTPSYAWYLGETAAKEGIDPRRDLAVRRIFVAGEPGG
ECCCCCHHHHHHHHHHHHHHEEECCCCEEEECCCHHHHCCCCHHHHHEEEEEEEECCCCC
SIPETRARIEALWGARVYDYYGLSDIFGACAGMCEERQGLHWAEDHILVEVLDPLTGEPV
CCCHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHCCCEEHHHHHHEEECCCCCCCCC
AEGERGELVLTTLRKRARPLIRFRVGDIVSFTSEPCACGRTSKRLLGVHGRVDDMLIIRG
CCCCCCCCHHHHHHHHCCCEEEEEHHHHHHCCCCCCCCCCCCHHHEECCCCCCCEEEEEC
VNIFPSDIEAIVRKDHDFTGEYRLVVERVDHLDALSVEVEHRAGLNTPPEALAARLRGQI
CCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCHHEEEEEHHHCCCCCCHHHHHHHHHCCE
KAVTGVGARVVVLAPDSLPRATHKAKRIDDRRTGVWTA
EEEECCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
STAHAPVLAPKAPSLASERRYWAPEIETRSRAEWDAQSLRLLQAHLRYAYGNAPYYRAR
CCCCCCEECCCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEE
FDAARVHPDDVRSLDDLRRFPLLDKGVLRARQQAVPLLGDLAAVPEDEVVYVSASSGSTG
CCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHCCCCCCEEEEECCCCCCC
VPTLSPFTAGDFDDWIDFEARLFWASGLRPSDRYAHSLNFSLFVGGPCVLGAQKLGALSI
CCCCCCCCCCCCHHHHCCEEEEEEECCCCCCHHHHHCCCEEEEECCCEEECHHHCCEEEE
HAGTVPSDRLLAILRQFQATAMWTTPSYAWYLGETAAKEGIDPRRDLAVRRIFVAGEPGG
ECCCCCHHHHHHHHHHHHHHEEECCCCEEEECCCHHHHCCCCHHHHHEEEEEEEECCCCC
SIPETRARIEALWGARVYDYYGLSDIFGACAGMCEERQGLHWAEDHILVEVLDPLTGEPV
CCCHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHCCCEEHHHHHHEEECCCCCCCCC
AEGERGELVLTTLRKRARPLIRFRVGDIVSFTSEPCACGRTSKRLLGVHGRVDDMLIIRG
CCCCCCCCHHHHHHHHCCCEEEEEHHHHHHCCCCCCCCCCCCHHHEECCCCCCCEEEEEC
VNIFPSDIEAIVRKDHDFTGEYRLVVERVDHLDALSVEVEHRAGLNTPPEALAARLRGQI
CCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCHHEEEEEHHHCCCCCCHHHHHHHHHCCE
KAVTGVGARVVVLAPDSLPRATHKAKRIDDRRTGVWTA
EEEECCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]