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The map label for this gene is cobS [H]

Identifier: 83591546

GI number: 83591546

Start: 255074

End: 256063

Strand: Direct

Name: cobS [H]

Synonym: Rru_A0206

Alternate gene names: 83591546

Gene position: 255074-256063 (Clockwise)

Preceding gene: 83591545

Following gene: 83591547

Centisome position: 5.86

GC content: 62.12

Gene sequence:

>990_bases
ATGGACGTCGCTGCTGAGTATCCCGTTGATAAACCCGACACCCAGGTTTCCGTGCGGGACGTGTTCGGTATCGAGTCCGA
TCTGACCGTGCCGGCCTTCACCGAGGTGTCCGAGCACGTTCCCGATCGCGACGACGCCTATTGCTTCGACCGCGACACCA
CTTTGGCCGTTCTCGCCGGGTTCGCCTTCAATCGCCGGGTGATGATCCAGGGCTATCACGGCACCGGCAAATCCACCCAT
ATCGAGCAGATCGCCTCGCGCCTCAACTGGCCGTGCATCCGCGTCAATCTTGACAGCCACGTCAGCCGCATCGATCTGGT
CGGCAAGGATGCCATCGTTTTGCGCGACGGGCTGCAGGTTACGGAATTCCGCGAGGGAATCCTCCCCTGGTGTCTGCAGC
GGCCGATCGCCCTGACCTTTGACGAATACGACGCCGGGCGGGCCGATGTGATGTTCGTCATCCAGCGGGTGCTCGAGGTC
GAAGGCCGGTTGACCCTGCTCGATCAGAACAAGGTGATCCGCCCCCACCCCTATTTCCGTCTGTTCGCCACCGCCAATAC
GGTTGGCCTGGGCGATACCACCGGGCTTTATCACGGCACCCAGCAGATCAATCAGGGGCAGATGGACCGCTGGAACATCG
TCGCCACGCTGAATTACCTGGAGCACGACGTGGAGGTGGGGATCGCCCTGGCCAAGCGTCCCGAATACGACACCCCCGAA
GGCCGGGCCAAGATCAACGCCATGGTCGGCGTGGCCGATCTGTCGCGCAGCGGCTTCATCAACGGCGATATCTCGACCGT
GATGTCGCCGCGCACCGTGCTGACCTGGGCCGAGAACGCCACCATCTTTGGCGATGACGCCTTCGCCTTCCGCGTGACCT
TCCTGAACAAATGCGACGAGACCGAACGTCCGATCATCGCCGAGTATTATCAGCGGTGCTTTGGTAAGGAGCTCCCCGAG
AGTGCGGCCTTCCGCACCGCCTTCCTGTGA

Upstream 100 bases:

>100_bases
CGTGCTGGTCAACGTCCTGAACGCGTGACATTCTGCCCGGCCGCCCCTGTGCGGTCCGCTTTTTCATCACCAAGCCGTTT
GCCTGAGAACGAGGAAGTCC

Downstream 100 bases:

>100_bases
GGCGCGGCGCGGGGCGGCGACAGGTCAGGGACGGATCGAAGCGATGACGCGTATTCCGGTGCCCGGTGCCGGCGGCCGGG
CGAACGAGCCGCAGGAAGCC

Product: hydrogenobyrinic acid a,c-diamide cobaltochelatase

Products: NA

Alternate protein names: Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobS [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MDVAAEYPVDKPDTQVSVRDVFGIESDLTVPAFTEVSEHVPDRDDAYCFDRDTTLAVLAGFAFNRRVMIQGYHGTGKSTH
IEQIASRLNWPCIRVNLDSHVSRIDLVGKDAIVLRDGLQVTEFREGILPWCLQRPIALTFDEYDAGRADVMFVIQRVLEV
EGRLTLLDQNKVIRPHPYFRLFATANTVGLGDTTGLYHGTQQINQGQMDRWNIVATLNYLEHDVEVGIALAKRPEYDTPE
GRAKINAMVGVADLSRSGFINGDISTVMSPRTVLTWAENATIFGDDAFAFRVTFLNKCDETERPIIAEYYQRCFGKELPE
SAAFRTAFL

Sequences:

>Translated_329_residues
MDVAAEYPVDKPDTQVSVRDVFGIESDLTVPAFTEVSEHVPDRDDAYCFDRDTTLAVLAGFAFNRRVMIQGYHGTGKSTH
IEQIASRLNWPCIRVNLDSHVSRIDLVGKDAIVLRDGLQVTEFREGILPWCLQRPIALTFDEYDAGRADVMFVIQRVLEV
EGRLTLLDQNKVIRPHPYFRLFATANTVGLGDTTGLYHGTQQINQGQMDRWNIVATLNYLEHDVEVGIALAKRPEYDTPE
GRAKINAMVGVADLSRSGFINGDISTVMSPRTVLTWAENATIFGDDAFAFRVTFLNKCDETERPIIAEYYQRCFGKELPE
SAAFRTAFL
>Mature_329_residues
MDVAAEYPVDKPDTQVSVRDVFGIESDLTVPAFTEVSEHVPDRDDAYCFDRDTTLAVLAGFAFNRRVMIQGYHGTGKSTH
IEQIASRLNWPCIRVNLDSHVSRIDLVGKDAIVLRDGLQVTEFREGILPWCLQRPIALTFDEYDAGRADVMFVIQRVLEV
EGRLTLLDQNKVIRPHPYFRLFATANTVGLGDTTGLYHGTQQINQGQMDRWNIVATLNYLEHDVEVGIALAKRPEYDTPE
GRAKINAMVGVADLSRSGFINGDISTVMSPRTVLTWAENATIFGDDAFAFRVTFLNKCDETERPIIAEYYQRCFGKELPE
SAAFRTAFL

Specific function: Catalyzes cobalt insertion in the corrin ring [H]

COG id: COG0714

COG function: function code R; MoxR-like ATPases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI24415404, Length=288, Percent_Identity=22.9166666666667, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI161076560, Length=124, Percent_Identity=29.8387096774194, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI161076562, Length=124, Percent_Identity=29.8387096774194, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011704
- InterPro:   IPR006537 [H]

Pfam domain/function: PF07728 AAA_5 [H]

EC number: =6.6.1.2 [H]

Molecular weight: Translated: 36990; Mature: 36990

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVAAEYPVDKPDTQVSVRDVFGIESDLTVPAFTEVSEHVPDRDDAYCFDRDTTLAVLAG
CCCCCCCCCCCCCCEEEHHHHHCCCCCCCCCCHHHHHHHCCCCCCCEEECCCCHHHHHHH
FAFNRRVMIQGYHGTGKSTHIEQIASRLNWPCIRVNLDSHVSRIDLVGKDAIVLRDGLQV
HHCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCEEEEECCCCH
TEFREGILPWCLQRPIALTFDEYDAGRADVMFVIQRVLEVEGRLTLLDQNKVIRPHPYFR
HHHHHCHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCEECCCCCEE
LFATANTVGLGDTTGLYHGTQQINQGQMDRWNIVATLNYLEHDVEVGIALAKRPEYDTPE
EEEECCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEEEHHHHHHHHHEEEEECCCCCCCCC
GRAKINAMVGVADLSRSGFINGDISTVMSPRTVLTWAENATIFGDDAFAFRVTFLNKCDE
CCEEEEEEEEEECCCCCCCCCCCHHHHCCCCEEEEEECCCEEECCCCEEEEEEEHHHCCC
TERPIIAEYYQRCFGKELPESAAFRTAFL
CCCCHHHHHHHHHHCCCCCHHHHHHHHCC
>Mature Secondary Structure
MDVAAEYPVDKPDTQVSVRDVFGIESDLTVPAFTEVSEHVPDRDDAYCFDRDTTLAVLAG
CCCCCCCCCCCCCCEEEHHHHHCCCCCCCCCCHHHHHHHCCCCCCCEEECCCCHHHHHHH
FAFNRRVMIQGYHGTGKSTHIEQIASRLNWPCIRVNLDSHVSRIDLVGKDAIVLRDGLQV
HHCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCEEEEECCCCH
TEFREGILPWCLQRPIALTFDEYDAGRADVMFVIQRVLEVEGRLTLLDQNKVIRPHPYFR
HHHHHCHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCEECCCCCEE
LFATANTVGLGDTTGLYHGTQQINQGQMDRWNIVATLNYLEHDVEVGIALAKRPEYDTPE
EEEECCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEEEHHHHHHHHHEEEEECCCCCCCCC
GRAKINAMVGVADLSRSGFINGDISTVMSPRTVLTWAENATIFGDDAFAFRVTFLNKCDE
CCEEEEEEEEEECCCCCCCCCCCHHHHCCCCEEEEEECCCEEECCCCEEEEEEEHHHCCC
TERPIIAEYYQRCFGKELPESAAFRTAFL
CCCCHHHHHHHHHHCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1917840 [H]