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The map label for this gene is dnaA [H]

Identifier: 83591341

GI number: 83591341

Start: 228

End: 1757

Strand: Direct

Name: dnaA [H]

Synonym: Rru_A0001

Alternate gene names: 83591341

Gene position: 228-1757 (Clockwise)

Preceding gene: NA

Following gene: 83591342

Centisome position: 0.01

GC content: 65.56

Gene sequence:

>1530_bases
ATGTACGAATCGTCGGGAGTCGCCGTGAACCCCCAGAACGGCAGTCTTGCCGGTGCTGATGGCTGCGACCTGAGTGCCAG
TTGGGACCGGGTGCGCGGCTTCTTGAAGCGGGAATTCGGCGACTCCGCCTATCGGACCTGGGTCGTGCCGATGACCCTGG
TCGCGGCGGTGGAGGGCGAGGTGCGTCTGGCCGTGCCGACGCGTTTCATGCGCGACTGGGTGATGAACCATTACGGGGAT
CGCATCCGCTCGCTGTGGGCGGCCGAGGATTCGTCGATTCGCTATGTCGATTTCATCGTCGAGAGCGCGCCCGCTCCCGC
TCCGCCGGCCCGCGCCGGTCAGGACGCCGACAGGGCGGAGGGCGCCTCCGATCCGGCGGCGGGCCAGCGGCCGGCCGAGG
CCGGCGCCCCACGCCCCGCCGCGCGCGCTTCGCGGACCATGGTGCGGGTGGCGGCCGAGGGTGGCGCCGAAGGAGCCGAC
TCGGCGCCGGCCCCCCTTGACGACGGCATTTCCGCCCCGCTCGATCCGCGCTTCACCTTTGATAACTTCGTTGTCGGCAA
GCCCAATGAGTTCGCCTATGCGGCGGCCAAACGGGTGGCCGATTCCACGGGGGTCGCCTTCAACCCCTTGTTCCTTTATG
GCGGCGTCGGTCTGGGCAAGACCCATCTGATGCATGCGATCGCCCGGGGCATCCGCGAGGCCTCGCCGCATCGCCGGGTG
ATCTATCTGTCGGCCGAGCAGTTCATGCACCGCTTCATCCGCGCCCTGCGCCAGCAAGACACCATGTCGTTCAAGGAGCA
GTTCCGCAGCGTCGAAGTGCTGATGGTCGATGACATTCAGTTCATCAGCGGCAAGGACAGCACCCAGGAAGAATTCTTCC
ACACCTTCAACGCCCTGGTCGATCAGGGCAGCCAGATCGTGCTGTCGGCCGACAAATCGCCCACCGATCTGGAAAACATC
GGCGCCCGCCTGCGCTCGCGCATGGCCTGCGGTCTGGTTGCCGATCTCCATCCCACCACCTATGAGCTGCGCCTGGGCAT
TCTTGAATCGAAGGCCGAGCACATGGGCGTTTCCGTGCCCGAAAAGGTCCTTGAATTCATCGCCCATAAGATCGCGTCGA
ACGGCCGCGAGGTTGAGGGCGCCCTGATCCGCCTGATCGCCCATGCTCAACTGGTCGGCCGCGATCTGACCCTGGAAACC
GCCCAGGATGTTCTGCACGACCTGCTGCGCACCTATGACAAGCGCGTCACCGTCGACGAAATTCAAAAGAAGGTCGCCGA
GCACTTCAAGATCCGCCTCGCCGATATGCATTCGGCCCGCCGCGCCCGGGCGGTGGCCCGGCCCCGGCAGGTGGCGATGT
ATCTCTGCAAGCAGCTGACCAGCCGTTCGCTGCCCGAAATCGGCAAAAGCTTCGGTGGCCGCGACCACACCACGGTCATG
CATGCGGTGCGCAAGGTCGAGGAACTGATCCTGGCCGATGGCACCTTCGCCGAGGATGTCGAACTGCTGCGGCGCATGCT
CGAGGCCTGA

Upstream 100 bases:

>100_bases
GGATGCCGAACGCCGTCCCGAATACGCGAGGATACGGGGGTTATTTCTGGAACGGCCTGGATCTGGGTCGGCCGAAGGAC
ACCCATTAGTGGAGCACGAG

Downstream 100 bases:

>100_bases
CGCCTCCGGCCCCCGGCGACTCCGTTTCCCGCCCCGGTTTTCGCCGTCTGCGGTTGAAAGGGAGGCGCCCCCTTCTCCTT
GCGGGCGTCGCCTGACGCGG

Product: chromosomal replication initiation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MYESSGVAVNPQNGSLAGADGCDLSASWDRVRGFLKREFGDSAYRTWVVPMTLVAAVEGEVRLAVPTRFMRDWVMNHYGD
RIRSLWAAEDSSIRYVDFIVESAPAPAPPARAGQDADRAEGASDPAAGQRPAEAGAPRPAARASRTMVRVAAEGGAEGAD
SAPAPLDDGISAPLDPRFTFDNFVVGKPNEFAYAAAKRVADSTGVAFNPLFLYGGVGLGKTHLMHAIARGIREASPHRRV
IYLSAEQFMHRFIRALRQQDTMSFKEQFRSVEVLMVDDIQFISGKDSTQEEFFHTFNALVDQGSQIVLSADKSPTDLENI
GARLRSRMACGLVADLHPTTYELRLGILESKAEHMGVSVPEKVLEFIAHKIASNGREVEGALIRLIAHAQLVGRDLTLET
AQDVLHDLLRTYDKRVTVDEIQKKVAEHFKIRLADMHSARRARAVARPRQVAMYLCKQLTSRSLPEIGKSFGGRDHTTVM
HAVRKVEELILADGTFAEDVELLRRMLEA

Sequences:

>Translated_509_residues
MYESSGVAVNPQNGSLAGADGCDLSASWDRVRGFLKREFGDSAYRTWVVPMTLVAAVEGEVRLAVPTRFMRDWVMNHYGD
RIRSLWAAEDSSIRYVDFIVESAPAPAPPARAGQDADRAEGASDPAAGQRPAEAGAPRPAARASRTMVRVAAEGGAEGAD
SAPAPLDDGISAPLDPRFTFDNFVVGKPNEFAYAAAKRVADSTGVAFNPLFLYGGVGLGKTHLMHAIARGIREASPHRRV
IYLSAEQFMHRFIRALRQQDTMSFKEQFRSVEVLMVDDIQFISGKDSTQEEFFHTFNALVDQGSQIVLSADKSPTDLENI
GARLRSRMACGLVADLHPTTYELRLGILESKAEHMGVSVPEKVLEFIAHKIASNGREVEGALIRLIAHAQLVGRDLTLET
AQDVLHDLLRTYDKRVTVDEIQKKVAEHFKIRLADMHSARRARAVARPRQVAMYLCKQLTSRSLPEIGKSFGGRDHTTVM
HAVRKVEELILADGTFAEDVELLRRMLEA
>Mature_509_residues
MYESSGVAVNPQNGSLAGADGCDLSASWDRVRGFLKREFGDSAYRTWVVPMTLVAAVEGEVRLAVPTRFMRDWVMNHYGD
RIRSLWAAEDSSIRYVDFIVESAPAPAPPARAGQDADRAEGASDPAAGQRPAEAGAPRPAARASRTMVRVAAEGGAEGAD
SAPAPLDDGISAPLDPRFTFDNFVVGKPNEFAYAAAKRVADSTGVAFNPLFLYGGVGLGKTHLMHAIARGIREASPHRRV
IYLSAEQFMHRFIRALRQQDTMSFKEQFRSVEVLMVDDIQFISGKDSTQEEFFHTFNALVDQGSQIVLSADKSPTDLENI
GARLRSRMACGLVADLHPTTYELRLGILESKAEHMGVSVPEKVLEFIAHKIASNGREVEGALIRLIAHAQLVGRDLTLET
AQDVLHDLLRTYDKRVTVDEIQKKVAEHFKIRLADMHSARRARAVARPRQVAMYLCKQLTSRSLPEIGKSFGGRDHTTVM
HAVRKVEELILADGTFAEDVELLRRMLEA

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family [H]

Homologues:

Organism=Escherichia coli, GI2367267, Length=486, Percent_Identity=41.1522633744856, Blast_Score=372, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921 [H]

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C [H]

EC number: NA

Molecular weight: Translated: 56020; Mature: 56020

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYESSGVAVNPQNGSLAGADGCDLSASWDRVRGFLKREFGDSAYRTWVVPMTLVAAVEGE
CCCCCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
VRLAVPTRFMRDWVMNHYGDRIRSLWAAEDSSIRYVDFIVESAPAPAPPARAGQDADRAE
EEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHCCCCCCCCCCCCCCCHHHC
GASDPAAGQRPAEAGAPRPAARASRTMVRVAAEGGAEGADSAPAPLDDGISAPLDPRFTF
CCCCCCCCCCCCCCCCCCCHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
DNFVVGKPNEFAYAAAKRVADSTGVAFNPLFLYGGVGLGKTHLMHAIARGIREASPHRRV
CCEEECCCCHHHHHHHHHHHCCCCCEECCHHEECCCCCCHHHHHHHHHHHHHHCCCCCEE
IYLSAEQFMHRFIRALRQQDTMSFKEQFRSVEVLMVDDIQFISGKDSTQEEFFHTFNALV
EEECHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHCCCCCHHHHHHHHHHHHH
DQGSQIVLSADKSPTDLENIGARLRSRMACGLVADLHPTTYELRLGILESKAEHMGVSVP
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCH
EKVLEFIAHKIASNGREVEGALIRLIAHAQLVGRDLTLETAQDVLHDLLRTYDKRVTVDE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHH
IQKKVAEHFKIRLADMHSARRARAVARPRQVAMYLCKQLTSRSLPEIGKSFGGRDHTTVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHH
HAVRKVEELILADGTFAEDVELLRRMLEA
HHHHHHHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MYESSGVAVNPQNGSLAGADGCDLSASWDRVRGFLKREFGDSAYRTWVVPMTLVAAVEGE
CCCCCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
VRLAVPTRFMRDWVMNHYGDRIRSLWAAEDSSIRYVDFIVESAPAPAPPARAGQDADRAE
EEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHCCCCCCCCCCCCCCCHHHC
GASDPAAGQRPAEAGAPRPAARASRTMVRVAAEGGAEGADSAPAPLDDGISAPLDPRFTF
CCCCCCCCCCCCCCCCCCCHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
DNFVVGKPNEFAYAAAKRVADSTGVAFNPLFLYGGVGLGKTHLMHAIARGIREASPHRRV
CCEEECCCCHHHHHHHHHHHCCCCCEECCHHEECCCCCCHHHHHHHHHHHHHHCCCCCEE
IYLSAEQFMHRFIRALRQQDTMSFKEQFRSVEVLMVDDIQFISGKDSTQEEFFHTFNALV
EEECHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHCCCCCHHHHHHHHHHHHH
DQGSQIVLSADKSPTDLENIGARLRSRMACGLVADLHPTTYELRLGILESKAEHMGVSVP
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCH
EKVLEFIAHKIASNGREVEGALIRLIAHAQLVGRDLTLETAQDVLHDLLRTYDKRVTVDE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHH
IQKKVAEHFKIRLADMHSARRARAVARPRQVAMYLCKQLTSRSLPEIGKSFGGRDHTTVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHH
HAVRKVEELILADGTFAEDVELLRRMLEA
HHHHHHHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA