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The map label for this gene is baeS [H]

Identifier: 83313399

GI number: 83313399

Start: 4704532

End: 4706016

Strand: Reverse

Name: baeS [H]

Synonym: amb4300

Alternate gene names: 83313399

Gene position: 4706016-4704532 (Counterclockwise)

Preceding gene: 83313400

Following gene: 83313398

Centisome position: 94.74

GC content: 70.03

Gene sequence:

>1485_bases
ATGCCTAGACTCGGACTCTGGCGGGGATCCTTCGCCGTCAAGCTGGCCAGCATCGCCCTGATCTTCGCCGTGGTGCCGGT
GTTGATCTACCTGCAGCTGGAGACGGTGGAGACCCAGCGCAACGCCCTGATGCTGCGCTTGGCCCAGGAACAGGGAAAGC
TGGCGGGCGAGGCGCTGTTCCCCCTGCTGGAGCAGTTCTCGCCGCGCAACGCCGACCGCATCGATCCGGTGGTCAGGCGC
CTGGGCGAGGGCGGCATGTCCATCAAGGTGCTGTTCCGGCCGGCCCAGTCCAATGGCGCCCGCAATTTCCTGCTGGTCGC
CTCGGCTCCCGAGACCGGGCCGCAACAGGCCCGTCCCGCCATGGACCGGCTGGTGGAGAGCGGCGTGCTTGCCCATCTGG
CCGCCAGTTGCGAGGGACGCGCCCCCCTGGCCCTGCGACTGGCCGGAATCCAGGAAGGCGGCGAGCTTCTGACCTATCTG
GCCCCCCATGCCACCCGCCTGGGCTGCTGGGTGGTGCTGACCGCCCAGCCCACCGGCACCCTGCCGGAGCAGGTGATCGG
CCGTCCCTACTGGCAATCCCCCGACCTTCAGGTGGCGGCCTCCATCTACCTGCTGATGGCGGTGCTGGTGCTGTCCATCT
TCACCGACGCCTGGGGCAATCTGCGGCGCTTCCAGGGGGTGGCGCGCTCGGTGGTCCGGGGCGAGGCCAAGGTCTCCTTC
GTCGAGGGCAACCGGGTCCCCGAACTGGCCGAGGTGGCCGCCGAGCTGGATTCCATGGTCGCCACCCTCAAGCGCTCGGA
AGGCTTGCTGCGCCAGGCGGCGGAGGAGAACGCCCATGCCCTCAAGGCGCCGTTGGCGGTGATCTCCCAATCCCTCGAGC
CCCTGGGGCGGGCGGTGGCCCCCGACAATGTCAGGGCGGTGCGTGCCCTCGACCTGATCGGCCAGTCGGTGGAGCGTCTG
GACGGGCTGGTCTCCACCATCCGCCGTACCGACGAGACCATCGCCGCCCTGATCGACCGCCCCCGTGACCGGGTCGATGC
CTCGGCCCTGCTCAACCGGTTGGGGCGGGGCTATATCCGCATGGCGGCCGAGCGCTCCGTCGGTCTGGACATGGGCGTCG
CCGCCGGGCTCTGGATTTCCGGCAGCGACGAGATGCTGGAGGTCATCGCCGAAAACCTGCTGGACAACGCCATCGACTTC
TCGCCCCCCGGTGGGCGGATTTCCATGGATCTGCGCCAGGAGAACGGCATGGCGCTGTTGCGGGTGCGCGACAACGGCCC
CGGCGTGCCGGAAGGCGAGCTGGAGCGCATCTTCGAGCGCCATGTTTCGCAGCGGGGCAAGGCCGAGGGCGGCCAGGTCG
AGCATTACGGCCTGGGCCTGTGGATCGTTCGCCGCAACGCCGAGGCCATGGGCGGCAAGGCCTGGGCCGCCGGCGCCCCC
GGTGGCGGCCTGGAGGTCTCGGTCGCTCTGCCGCTGGGCGACTGA

Upstream 100 bases:

>100_bases
GCCATCAAGCGCATCCGCGAGAAGTTCAAGACCGTCGATCCGGACTTCGAGCAGATCGGCAATTATCCCGGCTTCGGCTA
TGTCTGGCAGGCTGAGCGCG

Downstream 100 bases:

>100_bases
GCGTCTCAGTCACAGCTTTATCACAGCCTTCTCACCCCCCGGTTCCGGTCGCCGGCGTATTCCTATCAGGGATGGGCTCG
TCCCAGATTTGAAGGAATAA

Product: Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MPRLGLWRGSFAVKLASIALIFAVVPVLIYLQLETVETQRNALMLRLAQEQGKLAGEALFPLLEQFSPRNADRIDPVVRR
LGEGGMSIKVLFRPAQSNGARNFLLVASAPETGPQQARPAMDRLVESGVLAHLAASCEGRAPLALRLAGIQEGGELLTYL
APHATRLGCWVVLTAQPTGTLPEQVIGRPYWQSPDLQVAASIYLLMAVLVLSIFTDAWGNLRRFQGVARSVVRGEAKVSF
VEGNRVPELAEVAAELDSMVATLKRSEGLLRQAAEENAHALKAPLAVISQSLEPLGRAVAPDNVRAVRALDLIGQSVERL
DGLVSTIRRTDETIAALIDRPRDRVDASALLNRLGRGYIRMAAERSVGLDMGVAAGLWISGSDEMLEVIAENLLDNAIDF
SPPGGRISMDLRQENGMALLRVRDNGPGVPEGELERIFERHVSQRGKAEGGQVEHYGLGLWIVRRNAEAMGGKAWAAGAP
GGGLEVSVALPLGD

Sequences:

>Translated_494_residues
MPRLGLWRGSFAVKLASIALIFAVVPVLIYLQLETVETQRNALMLRLAQEQGKLAGEALFPLLEQFSPRNADRIDPVVRR
LGEGGMSIKVLFRPAQSNGARNFLLVASAPETGPQQARPAMDRLVESGVLAHLAASCEGRAPLALRLAGIQEGGELLTYL
APHATRLGCWVVLTAQPTGTLPEQVIGRPYWQSPDLQVAASIYLLMAVLVLSIFTDAWGNLRRFQGVARSVVRGEAKVSF
VEGNRVPELAEVAAELDSMVATLKRSEGLLRQAAEENAHALKAPLAVISQSLEPLGRAVAPDNVRAVRALDLIGQSVERL
DGLVSTIRRTDETIAALIDRPRDRVDASALLNRLGRGYIRMAAERSVGLDMGVAAGLWISGSDEMLEVIAENLLDNAIDF
SPPGGRISMDLRQENGMALLRVRDNGPGVPEGELERIFERHVSQRGKAEGGQVEHYGLGLWIVRRNAEAMGGKAWAAGAP
GGGLEVSVALPLGD
>Mature_493_residues
PRLGLWRGSFAVKLASIALIFAVVPVLIYLQLETVETQRNALMLRLAQEQGKLAGEALFPLLEQFSPRNADRIDPVVRRL
GEGGMSIKVLFRPAQSNGARNFLLVASAPETGPQQARPAMDRLVESGVLAHLAASCEGRAPLALRLAGIQEGGELLTYLA
PHATRLGCWVVLTAQPTGTLPEQVIGRPYWQSPDLQVAASIYLLMAVLVLSIFTDAWGNLRRFQGVARSVVRGEAKVSFV
EGNRVPELAEVAAELDSMVATLKRSEGLLRQAAEENAHALKAPLAVISQSLEPLGRAVAPDNVRAVRALDLIGQSVERLD
GLVSTIRRTDETIAALIDRPRDRVDASALLNRLGRGYIRMAAERSVGLDMGVAAGLWISGSDEMLEVIAENLLDNAIDFS
PPGGRISMDLRQENGMALLRVRDNGPGVPEGELERIFERHVSQRGKAEGGQVEHYGLGLWIVRRNAEAMGGKAWAAGAPG
GGLEVSVALPLGD

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=251, Percent_Identity=28.6852589641434, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1790861, Length=275, Percent_Identity=30.9090909090909, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786600, Length=232, Percent_Identity=25.8620689655172, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790567, Length=176, Percent_Identity=27.2727272727273, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI145693157, Length=276, Percent_Identity=26.0869565217391, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53136; Mature: 53005

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRLGLWRGSFAVKLASIALIFAVVPVLIYLQLETVETQRNALMLRLAQEQGKLAGEALF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
PLLEQFSPRNADRIDPVVRRLGEGGMSIKVLFRPAQSNGARNFLLVASAPETGPQQARPA
HHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEEEEECCCCCHHHHHHH
MDRLVESGVLAHLAASCEGRAPLALRLAGIQEGGELLTYLAPHATRLGCWVVLTAQPTGT
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHCCCCCEEEEEEEEEECCCCC
LPEQVIGRPYWQSPDLQVAASIYLLMAVLVLSIFTDAWGNLRRFQGVARSVVRGEAKVSF
CCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
VEGNRVPELAEVAAELDSMVATLKRSEGLLRQAAEENAHALKAPLAVISQSLEPLGRAVA
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PDNVRAVRALDLIGQSVERLDGLVSTIRRTDETIAALIDRPRDRVDASALLNRLGRGYIR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHCCCCEE
MAAERSVGLDMGVAAGLWISGSDEMLEVIAENLLDNAIDFSPPGGRISMDLRQENGMALL
EHHHHCCCCCCCHHCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEE
RVRDNGPGVPEGELERIFERHVSQRGKAEGGQVEHYGLGLWIVRRNAEAMGGKAWAAGAP
EEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEECCCHHCCCCEEECCCC
GGGLEVSVALPLGD
CCCEEEEEEECCCC
>Mature Secondary Structure 
PRLGLWRGSFAVKLASIALIFAVVPVLIYLQLETVETQRNALMLRLAQEQGKLAGEALF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
PLLEQFSPRNADRIDPVVRRLGEGGMSIKVLFRPAQSNGARNFLLVASAPETGPQQARPA
HHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEEEEECCCCCHHHHHHH
MDRLVESGVLAHLAASCEGRAPLALRLAGIQEGGELLTYLAPHATRLGCWVVLTAQPTGT
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHCCCCCEEEEEEEEEECCCCC
LPEQVIGRPYWQSPDLQVAASIYLLMAVLVLSIFTDAWGNLRRFQGVARSVVRGEAKVSF
CCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
VEGNRVPELAEVAAELDSMVATLKRSEGLLRQAAEENAHALKAPLAVISQSLEPLGRAVA
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PDNVRAVRALDLIGQSVERLDGLVSTIRRTDETIAALIDRPRDRVDASALLNRLGRGYIR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHCCCCEE
MAAERSVGLDMGVAAGLWISGSDEMLEVIAENLLDNAIDFSPPGGRISMDLRQENGMALL
EHHHHCCCCCCCHHCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEE
RVRDNGPGVPEGELERIFERHVSQRGKAEGGQVEHYGLGLWIVRRNAEAMGGKAWAAGAP
EEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEECCCHHCCCCEEECCCC
GGGLEVSVALPLGD
CCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]