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The map label for this gene is typA [H]

Identifier: 83313281

GI number: 83313281

Start: 4597580

End: 4598569

Strand: Reverse

Name: typA [H]

Synonym: amb4182

Alternate gene names: 83313281

Gene position: 4598569-4597580 (Counterclockwise)

Preceding gene: 83313282

Following gene: 83313279

Centisome position: 92.58

GC content: 65.66

Gene sequence:

>990_bases
ATGACCAAGCCCACCGTGGCCGACACCATCTGCGCCCCCGAGGTCACCGAGCCCCTCAAGGCCAATCCCATCGACCCGCC
GACCCTGTCCATGACCTTCTCGGTCAACGACAGCCCGCTGGCCGGTCAGGAAGGCGACAAGGTCACCTCGCGCATGATCG
CCGCCCGTCTGGCCCGTGAAGCCGAGTCCAACGTCGCCATCCATATCCGCGAGACCGCCGGCAAGGACGCCTTCGAGGTG
TCGGGCCGTGGCGAGCTGCAGCTGGGCGTGCTGATCGAGCAGATGCGCCGCGAGGGCTTCGAGCTGTCCATCTCGCGCCC
CCGCGTGCTGTTCAAGACCGATGATGCCGGCAAGCGCCTGGAGCCCATCGAGGAAGTGTTCATCGACGTGGACGACGAAT
ATTCCGGCGTCGTGGTCGAGAAGATGAGCCTGCGCAAGGCCGAACTCACCGGCATGCGCCCGTCGGGCGGCGGCAAGACC
CGCGTCACCTTCCTGGCGCCCGCCCGCGGCCTGATCGGCTATCACGGCGAGTTCCTCACCGACACCCGCGGCACCGGCCT
GATGAACCGCATGTTCCACGGCTATGCCCCCTACAAGGGCGCCATCGAGGGCCGCCGCAACGGCGTGCTGATCTCCAACG
GCCAGGGCGACGCGGTGACCTACGCGCTGTGGAACCTTGAAGATCGCGGCTCCATGTTCATCACCGGCAACGTGAAGATC
TACGAGGGCATGATCATCGGCGAGCACAATCGCCCCAATGACCTCGAAGTCAACGCGCTGAAGGCCAAGCAGCTCACCAA
CATCCGCGCCGCCGGCAAGGACGAGGCCGTCAAGCTGACCCCGCCCCGCAAGATGAGCCTGGAACAGGCCATCGCCTATA
TCGAGGACGATGAACTGGTGGAAGTGACGCCCAAGTCCATCCGCCTGCGCAAGCGCCTGCTCGACCCCAACGAGCGCAAG
AAGGCCGATCGCGCCGCCAAGAACGACTAA

Upstream 100 bases:

>100_bases
TGCTCGACAGTTCCGTCTCTCCAAGCTGCTGGCCTTCCGCGGCATCGAGCGCATTCCGGTGGAAAGCGCCGAGGCGGGCG
ACATCATCGCCATCGCCGGC

Downstream 100 bases:

>100_bases
ACGAAAAGGGCGACCCTCGGGTCGCCCTTCTTGTTTGTGGCTCGGCCACTTTCCGTCGAAGGGGAGGGGGAGATCCTTGT
GGGCTCTGCCCACGCCCGCA

Product: stress response membrane GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MTKPTVADTICAPEVTEPLKANPIDPPTLSMTFSVNDSPLAGQEGDKVTSRMIAARLAREAESNVAIHIRETAGKDAFEV
SGRGELQLGVLIEQMRREGFELSISRPRVLFKTDDAGKRLEPIEEVFIDVDDEYSGVVVEKMSLRKAELTGMRPSGGGKT
RVTFLAPARGLIGYHGEFLTDTRGTGLMNRMFHGYAPYKGAIEGRRNGVLISNGQGDAVTYALWNLEDRGSMFITGNVKI
YEGMIIGEHNRPNDLEVNALKAKQLTNIRAAGKDEAVKLTPPRKMSLEQAIAYIEDDELVEVTPKSIRLRKRLLDPNERK
KADRAAKND

Sequences:

>Translated_329_residues
MTKPTVADTICAPEVTEPLKANPIDPPTLSMTFSVNDSPLAGQEGDKVTSRMIAARLAREAESNVAIHIRETAGKDAFEV
SGRGELQLGVLIEQMRREGFELSISRPRVLFKTDDAGKRLEPIEEVFIDVDDEYSGVVVEKMSLRKAELTGMRPSGGGKT
RVTFLAPARGLIGYHGEFLTDTRGTGLMNRMFHGYAPYKGAIEGRRNGVLISNGQGDAVTYALWNLEDRGSMFITGNVKI
YEGMIIGEHNRPNDLEVNALKAKQLTNIRAAGKDEAVKLTPPRKMSLEQAIAYIEDDELVEVTPKSIRLRKRLLDPNERK
KADRAAKND
>Mature_328_residues
TKPTVADTICAPEVTEPLKANPIDPPTLSMTFSVNDSPLAGQEGDKVTSRMIAARLAREAESNVAIHIRETAGKDAFEVS
GRGELQLGVLIEQMRREGFELSISRPRVLFKTDDAGKRLEPIEEVFIDVDDEYSGVVVEKMSLRKAELTGMRPSGGGKTR
VTFLAPARGLIGYHGEFLTDTRGTGLMNRMFHGYAPYKGAIEGRRNGVLISNGQGDAVTYALWNLEDRGSMFITGNVKIY
EGMIIGEHNRPNDLEVNALKAKQLTNIRAAGKDEAVKLTPPRKMSLEQAIAYIEDDELVEVTPKSIRLRKRLLDPNERKK
ADRAAKND

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Escherichia coli, GI48994988, Length=325, Percent_Identity=52.9230769230769, Blast_Score=348, Evalue=3e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 36296; Mature: 36165

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPTVADTICAPEVTEPLKANPIDPPTLSMTFSVNDSPLAGQEGDKVTSRMIAARLARE
CCCCCCCHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
AESNVAIHIRETAGKDAFEVSGRGELQLGVLIEQMRREGFELSISRPRVLFKTDDAGKRL
CCCCEEEEEECCCCCCEEEECCCCCEEHHHHHHHHHHCCCEEEECCCEEEEEECCCCCCC
EPIEEVFIDVDDEYSGVVVEKMSLRKAELTGMRPSGGGKTRVTFLAPARGLIGYHGEFLT
CCHHHHEEECCCCCCCEEEEHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCEEE
DTRGTGLMNRMFHGYAPYKGAIEGRRNGVLISNGQGDAVTYALWNLEDRGSMFITGNVKI
CCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEEEEEEEECCCCCEEEEECEEE
YEGMIIGEHNRPNDLEVNALKAKQLTNIRAAGKDEAVKLTPPRKMSLEQAIAYIEDDELV
EEEEEEECCCCCCCEEEEEEHHHHHHHHHCCCCCCEEEECCCHHHCHHHHHHHCCCCCEE
EVTPKSIRLRKRLLDPNERKKADRAAKND
EECHHHHHHHHHHCCCCHHHHHHHHCCCC
>Mature Secondary Structure 
TKPTVADTICAPEVTEPLKANPIDPPTLSMTFSVNDSPLAGQEGDKVTSRMIAARLARE
CCCCCCHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
AESNVAIHIRETAGKDAFEVSGRGELQLGVLIEQMRREGFELSISRPRVLFKTDDAGKRL
CCCCEEEEEECCCCCCEEEECCCCCEEHHHHHHHHHHCCCEEEECCCEEEEEECCCCCCC
EPIEEVFIDVDDEYSGVVVEKMSLRKAELTGMRPSGGGKTRVTFLAPARGLIGYHGEFLT
CCHHHHEEECCCCCCCEEEEHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCEEE
DTRGTGLMNRMFHGYAPYKGAIEGRRNGVLISNGQGDAVTYALWNLEDRGSMFITGNVKI
CCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEEEEEEEECCCCCEEEEECEEE
YEGMIIGEHNRPNDLEVNALKAKQLTNIRAAGKDEAVKLTPPRKMSLEQAIAYIEDDELV
EEEEEEECCCCCCCEEEEEEHHHHHHHHHCCCCCCEEEECCCHHHCHHHHHHHCCCCCEE
EVTPKSIRLRKRLLDPNERKKADRAAKND
EECHHHHHHHHHHCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]