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The map label for this gene is 83313040

Identifier: 83313040

GI number: 83313040

Start: 4351335

End: 4352219

Strand: Reverse

Name: 83313040

Synonym: amb3941

Alternate gene names: NA

Gene position: 4352219-4351335 (Counterclockwise)

Preceding gene: 83313047

Following gene: 83313039

Centisome position: 87.62

GC content: 67.91

Gene sequence:

>885_bases
TTGGCCGCCCTTCCCGCCGGAGCCCGACCCATGGCCTTCCTGGACCATATCCGAACCTGCAACCGCCATGACCTGTCCAA
GTTCCGGCCGTTCTCGGTGGAGGGGAAATGGATCGGCTGGGTGCGCCACGACGTGGCCCAGCGTCTGGCGGCGTTTCCCG
AGGCGTTCCGCGTCTCGGTCGAAGGGGTCAGCCTCCATCCCGCCCTGTCCACCCCCGAGGCGCGCAGCGCCGCCATCGAC
GAGGTGACGCGGGAACTGGCCGAGGATTGGGGCACGCCCAAGGCGCGGGGCGAGCGCTATCGGGTGGCGGCCCGCTTCGG
CGATCCGGCCCTGATGAGCATCGACCGCGGCGTGGTCAGCCTGTTCGGCATCCGCGCCTATGGCGTCCACGTCAACGGTC
TGGTACGCCGCCCTGACGGCCTTCACCTGTGGATCGGGCGCCGCGCCAAGGACAAGAGCGTGGCGCCCGGTAAGCTGGAC
AACATGGTGGCGGGCGGTCAGCCCAGCGACCTGTCCCTGGCCGAGAACCTGATCAAGGAAGCGGCCGAGGAGGCCGACAT
TCCGCGTGAACTGGCGGCCACCGCCCGGCCGGCGGGGGTGGTGTCCTACTGTCTGGAGGACGATTGGGGGCTCAAGCCGG
ACGTGATGTTCTGCTATGACCTGGAGGTGCCCGAGACCTTCACGCCGCGCAACACCGACGGCGAGCTTCAGGGCTTCACC
CTGATGCCGGTGGCCGAGGTGGCGCGGCTGGTCAGGGATACCGACGAGTTCAAGTTCAACGTCAACCTGGTGATCCTCGA
CTTTCTGATCCGGCACGGCCTGATCTCGCCCGATGTCGAGCACGATTACGTGGACCTGGTGGGCGGCCTTCGGAAGGGCT
GGTGA

Upstream 100 bases:

>100_bases
TTCCCGTGGCGAGAACAGGGGGTGGCAGCATCGTATGAATATTTCTTAAACGAATTTTGCCGTGTGGCAGCCTTGACGGC
AGCTCCGACGGGCGTCACCC

Downstream 100 bases:

>100_bases
GGCCCGTCTGTCATTCCGAGCAAAGCGAGGAATCTCCGCCCGGATACTGGGGGCCGATTCTGACGGATCGCGCCAGGATG
AGATCCTTCCTCCCCTCTGG

Product: NTP pyrophosphohydrolase including oxidative damage repair enzyme

Products: AMP; thiamine diphosphate

Alternate protein names: Thiamin Pyrophosphokinase; NUDIX Domain-Containing Protein; Nucleoside Diphosphate; Thiamine Pyrophosphokinase; Nucleoside Diphosphate Hydrolase Protein; NTP Pyrophosphohydrolase; MutT/Nudix Family Protein; NUDIX Domain Family Protein; Nudix Family Protein; NTP Pyrophosphohydrolase Including Oxidative Damage Repair; Hydrolase NUDIX Family

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MAALPAGARPMAFLDHIRTCNRHDLSKFRPFSVEGKWIGWVRHDVAQRLAAFPEAFRVSVEGVSLHPALSTPEARSAAID
EVTRELAEDWGTPKARGERYRVAARFGDPALMSIDRGVVSLFGIRAYGVHVNGLVRRPDGLHLWIGRRAKDKSVAPGKLD
NMVAGGQPSDLSLAENLIKEAAEEADIPRELAATARPAGVVSYCLEDDWGLKPDVMFCYDLEVPETFTPRNTDGELQGFT
LMPVAEVARLVRDTDEFKFNVNLVILDFLIRHGLISPDVEHDYVDLVGGLRKGW

Sequences:

>Translated_294_residues
MAALPAGARPMAFLDHIRTCNRHDLSKFRPFSVEGKWIGWVRHDVAQRLAAFPEAFRVSVEGVSLHPALSTPEARSAAID
EVTRELAEDWGTPKARGERYRVAARFGDPALMSIDRGVVSLFGIRAYGVHVNGLVRRPDGLHLWIGRRAKDKSVAPGKLD
NMVAGGQPSDLSLAENLIKEAAEEADIPRELAATARPAGVVSYCLEDDWGLKPDVMFCYDLEVPETFTPRNTDGELQGFT
LMPVAEVARLVRDTDEFKFNVNLVILDFLIRHGLISPDVEHDYVDLVGGLRKGW
>Mature_293_residues
AALPAGARPMAFLDHIRTCNRHDLSKFRPFSVEGKWIGWVRHDVAQRLAAFPEAFRVSVEGVSLHPALSTPEARSAAIDE
VTRELAEDWGTPKARGERYRVAARFGDPALMSIDRGVVSLFGIRAYGVHVNGLVRRPDGLHLWIGRRAKDKSVAPGKLDN
MVAGGQPSDLSLAENLIKEAAEEADIPRELAATARPAGVVSYCLEDDWGLKPDVMFCYDLEVPETFTPRNTDGELQGFTL
MPVAEVARLVRDTDEFKFNVNLVILDFLIRHGLISPDVEHDYVDLVGGLRKGW

Specific function: Unknown

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Saccharomyces cerevisiae, GI6322602, Length=259, Percent_Identity=31.2741312741313, Blast_Score=123, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.6.2

Molecular weight: Translated: 32551; Mature: 32420

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAALPAGARPMAFLDHIRTCNRHDLSKFRPFSVEGKWIGWVRHDVAQRLAAFPEAFRVSV
CCCCCCCCCHHHHHHHHHCCCCCCHHHCCCCCCCCCEEHHHHHHHHHHHHHCCHHHEEEE
EGVSLHPALSTPEARSAAIDEVTRELAEDWGTPKARGERYRVAARFGDPALMSIDRGVVS
CCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHH
LFGIRAYGVHVNGLVRRPDGLHLWIGRRAKDKSVAPGKLDNMVAGGQPSDLSLAENLIKE
HHHHHEEEEEEEEEEECCCCEEEEECCCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHH
AAEEADIPRELAATARPAGVVSYCLEDDWGLKPDVMFCYDLEVPETFTPRNTDGELQGFT
HHHHCCCCHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEE
LMPVAEVARLVRDTDEFKFNVNLVILDFLIRHGLISPDVEHDYVDLVGGLRKGW
ECCHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
AALPAGARPMAFLDHIRTCNRHDLSKFRPFSVEGKWIGWVRHDVAQRLAAFPEAFRVSV
CCCCCCCCHHHHHHHHHCCCCCCHHHCCCCCCCCCEEHHHHHHHHHHHHHCCHHHEEEE
EGVSLHPALSTPEARSAAIDEVTRELAEDWGTPKARGERYRVAARFGDPALMSIDRGVVS
CCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHH
LFGIRAYGVHVNGLVRRPDGLHLWIGRRAKDKSVAPGKLDNMVAGGQPSDLSLAENLIKE
HHHHHEEEEEEEEEEECCCCEEEEECCCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHH
AAEEADIPRELAATARPAGVVSYCLEDDWGLKPDVMFCYDLEVPETFTPRNTDGELQGFT
HHHHCCCCHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEE
LMPVAEVARLVRDTDEFKFNVNLVILDFLIRHGLISPDVEHDYVDLVGGLRKGW
ECCHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; thiamine

Specific reaction: ATP + thiamine = AMP + thiamine diphosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA