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The map label for this gene is pdxY [H]

Identifier: 83313047

GI number: 83313047

Start: 4356081

End: 4357016

Strand: Reverse

Name: pdxY [H]

Synonym: amb3949

Alternate gene names: 83313047

Gene position: 4357016-4356081 (Counterclockwise)

Preceding gene: 83313053

Following gene: 83313040

Centisome position: 87.72

GC content: 69.02

Gene sequence:

>936_bases
ATGGACGAAACTCCCGAAAATGACAAAAGGCGGGGCAGACTACCCGAAGGCCCGGTTGCGGCGCAACATTGCATCGTCTA
TACCGGCCGCGACATGAAGATTCTTTCTTTCCAGTCGGCGGTGACCTTCGGCCATGTGGGCAATTCCGCCGCCCTGTTCG
CCCTGCAGCGCCTGGGGCTGGACGCCTGTCCGGTGGATACGGTGCAGTTCTCCAACCATCCCGGCCACGGAGCCTGGCGT
GGCCGCGCGCTTCCGGCCGAAGCCCTGGGCGAGATGGTCGACGGGCTGGAGGGGGCCGGATTGCTGGACGCTTTCGGCGC
GGTGCTGTCGGGCTATCTCGGCCAGGCCGGAACCGGCGACGTGGTGGCCGGGGCGGTGCGCCGTCTGCGGCGCCTGCGTC
CGGACGCCCTGTATCTCTGCGACCCGGTGATGGGCGACGAGGGGCGGCTTTACGTCGATGCCGGCATTCCCGAGATTTTC
GCCCGGACCCTGTTGCCCCTGGCCGATCTGGCCACCCCCAACCGGTTCGAGCTGGGATTGCTGACCGGTCGGTCGATCAA
CGACGTGGCGGATGCCTTGGCGGCGTCGCACGTGCTGATGGCGGGCGGAGTCAAGGCGGTGGTGACCACCAGCCTGCCGG
CGGGGGATGGCCTGATCGGCTGTCTGGCGGTGGACGGCCAGGGCGCATGGCTGGTGCGCACGCCCCTGCTGCCCTTTGCC
ACGCCGCCCAATGGCGGCGGCGACACCTTGTCGGCGCTGCTGCTCGGCCATGTCCTCAAGGGACGGGCCTTGCCTGAGGC
GCTGTCCCTGGCGGTGTCCAGCCTGTTCGGCATTCTGGAGGCGACGCGGAGCCGGGGCGGGCGGGAGATGGCCCTGGTGG
CGGGGCAGGACGAGATCGCCCTGCCCACTACGCTCTTTCCGCCTCTGCCGGTTTAG

Upstream 100 bases:

>100_bases
GATCAGCCCGTCGGCGGGGAGCGTGCGGGCTTTTTCCAGGGTGCGCGGATTGGAGCCGGGCATGTAGAGGACGGAACGGC
GGGGCCGCGCGGTGGTCGCC

Downstream 100 bases:

>100_bases
GTCTTCGCCGGAATCGACGTGGCTGTCGCCGTCGCCGTGGTGACAGCCGGAGCGGGCGGAGCCGCCGCGGCCACGGACGC
GGTTGCCGAACGCAGCTTCT

Product: pyridoxal/pyridoxine/pyridoxamine kinase

Products: NA

Alternate protein names: PM kinase [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MDETPENDKRRGRLPEGPVAAQHCIVYTGRDMKILSFQSAVTFGHVGNSAALFALQRLGLDACPVDTVQFSNHPGHGAWR
GRALPAEALGEMVDGLEGAGLLDAFGAVLSGYLGQAGTGDVVAGAVRRLRRLRPDALYLCDPVMGDEGRLYVDAGIPEIF
ARTLLPLADLATPNRFELGLLTGRSINDVADALAASHVLMAGGVKAVVTTSLPAGDGLIGCLAVDGQGAWLVRTPLLPFA
TPPNGGGDTLSALLLGHVLKGRALPEALSLAVSSLFGILEATRSRGGREMALVAGQDEIALPTTLFPPLPV

Sequences:

>Translated_311_residues
MDETPENDKRRGRLPEGPVAAQHCIVYTGRDMKILSFQSAVTFGHVGNSAALFALQRLGLDACPVDTVQFSNHPGHGAWR
GRALPAEALGEMVDGLEGAGLLDAFGAVLSGYLGQAGTGDVVAGAVRRLRRLRPDALYLCDPVMGDEGRLYVDAGIPEIF
ARTLLPLADLATPNRFELGLLTGRSINDVADALAASHVLMAGGVKAVVTTSLPAGDGLIGCLAVDGQGAWLVRTPLLPFA
TPPNGGGDTLSALLLGHVLKGRALPEALSLAVSSLFGILEATRSRGGREMALVAGQDEIALPTTLFPPLPV
>Mature_311_residues
MDETPENDKRRGRLPEGPVAAQHCIVYTGRDMKILSFQSAVTFGHVGNSAALFALQRLGLDACPVDTVQFSNHPGHGAWR
GRALPAEALGEMVDGLEGAGLLDAFGAVLSGYLGQAGTGDVVAGAVRRLRRLRPDALYLCDPVMGDEGRLYVDAGIPEIF
ARTLLPLADLATPNRFELGLLTGRSINDVADALAASHVLMAGGVKAVVTTSLPAGDGLIGCLAVDGQGAWLVRTPLLPFA
TPPNGGGDTLSALLLGHVLKGRALPEALSLAVSSLFGILEATRSRGGREMALVAGQDEIALPTTLFPPLPV

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=268, Percent_Identity=34.3283582089552, Blast_Score=142, Evalue=3e-34,
Organism=Escherichia coli, GI1787924, Length=279, Percent_Identity=39.0681003584229, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1788758, Length=267, Percent_Identity=33.3333333333333, Blast_Score=130, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17507759, Length=292, Percent_Identity=33.5616438356164, Blast_Score=143, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI17507757, Length=303, Percent_Identity=32.3432343234323, Blast_Score=137, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6324354, Length=250, Percent_Identity=36.8, Blast_Score=119, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6320806, Length=279, Percent_Identity=32.258064516129, Blast_Score=118, Evalue=1e-27,
Organism=Drosophila melanogaster, GI45553007, Length=300, Percent_Identity=32.6666666666667, Blast_Score=155, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 32295; Mature: 32295

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDETPENDKRRGRLPEGPVAAQHCIVYTGRDMKILSFQSAVTFGHVGNSAALFALQRLGL
CCCCCCCHHHCCCCCCCCCCCCEEEEEECCCEEEEEHHHHHEECCCCCHHHHHHHHHCCC
DACPVDTVQFSNHPGHGAWRGRALPAEALGEMVDGLEGAGLLDAFGAVLSGYLGQAGTGD
CCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCH
VVAGAVRRLRRLRPDALYLCDPVMGDEGRLYVDAGIPEIFARTLLPLADLATPNRFELGL
HHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCEEEEE
LTGRSINDVADALAASHVLMAGGVKAVVTTSLPAGDGLIGCLAVDGQGAWLVRTPLLPFA
ECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEECCCCCEEEECCCCCCC
TPPNGGGDTLSALLLGHVLKGRALPEALSLAVSSLFGILEATRSRGGREMALVAGQDEIA
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
LPTTLFPPLPV
CCCCCCCCCCC
>Mature Secondary Structure
MDETPENDKRRGRLPEGPVAAQHCIVYTGRDMKILSFQSAVTFGHVGNSAALFALQRLGL
CCCCCCCHHHCCCCCCCCCCCCEEEEEECCCEEEEEHHHHHEECCCCCHHHHHHHHHCCC
DACPVDTVQFSNHPGHGAWRGRALPAEALGEMVDGLEGAGLLDAFGAVLSGYLGQAGTGD
CCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCH
VVAGAVRRLRRLRPDALYLCDPVMGDEGRLYVDAGIPEIFARTLLPLADLATPNRFELGL
HHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCEEEEE
LTGRSINDVADALAASHVLMAGGVKAVVTTSLPAGDGLIGCLAVDGQGAWLVRTPLLPFA
ECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEECCCCCEEEECCCCCCC
TPPNGGGDTLSALLLGHVLKGRALPEALSLAVSSLFGILEATRSRGGREMALVAGQDEIA
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
LPTTLFPPLPV
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA