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The map label for this gene is cph1 [H]

Identifier: 83312725

GI number: 83312725

Start: 3986083

End: 3987729

Strand: Reverse

Name: cph1 [H]

Synonym: amb3626

Alternate gene names: 83312725

Gene position: 3987729-3986083 (Counterclockwise)

Preceding gene: 83312727

Following gene: 83312719

Centisome position: 80.28

GC content: 65.94

Gene sequence:

>1647_bases
ATGCTGGGGCCGATCCGGGAGTTCGTCTCCCTGGAAGGCGGTTTCGCGCTTTACTACGTGTTGGCCGGGCTGGGCTATGT
GGCGATCCTCATCGCCTTGATGCTGGTGGATTCCGACCGCCTGGCCGCCGTACTGGGCGAGGAGGTCTCACGCCAGGCCG
AGGCTCTGGAAACCCAGGTCGAACGGCAGGTCCAGGCGCGGGAGGATCTGCGGGCCATTCTCGACAACATGCCCGACATC
TTCTATCGCACCGACACCGAGGGGCGGCTGCTGATGGTGTCGCGTTCGGTGGAGGGTCTGCTCGGCTACACGGTGGAGGA
GGTGCTGGGGCTGGACTCCGCCTTCTTCCACGGCAGTGATGACAGCCGCCCCCAACTGGTGGCCGCCCTCGAAGCCGCCG
GCGGTTCGATCATCGATTACGAGCTCCGACTGCGCCACAAGGATGGCCGCATCCTGTGGGCCTCCACCTCGTCGCGCTTC
TATCTCGACGCCCAGGGGCGGCGGGGGGGGACCGAGGGTGTCGTCCGCCTGATCGAGGAGCGCAAGCGCACCGAACTCTA
TATCCGTGAGAACCAAGCCCTGATTCAGGCCATGCTGGACGCCTCGTCGGACGCCATCATGCTGTTCCGGCCCGACGGCA
CCTTGTTGGCGGTCAACGAGGTGATGGCGGCGCGCTTCGGGCGCCGGGCCACCGAACTGACAGGAAGCTGCCTGTGGGAC
ATGTTCCCGCCGGATGTGGCCAAGGCCCGCGAGGAGGCGGTGACCCGGGTGGTGCAGACCGGCGAAGCCATCCACTACCT
GGATCGGCGCGGCGATCTCTATCTCGACAATTCCATCTATCCCGTCCCCGGGGTGGATGGCGTTCCCGACAAGGTGGCGG
TTTATTCCCGCGACATCACCGCCCAGACCCTGGCCGAGCAGAAGGTGGCCACCTATTTGGCCGAGCTGGAACGCTCCAAT
GCCGAGTTGGAGCAGTTCGCCTACGTGGCCAGCCACGATCTGCGCGAGCCGCTGCGCATGATCTCCAGCTATCTCTCCCT
GCTGGAGCGGCGCTATGCCCCCAAGCTGGAAGGCGACGGCCTGGAATTCCTGGCCTTTGCCCGCGACGGCGCCCAGCGCA
TGGATCGGCTGGTGCTGGATCTGCTGGATTTCTCGCGCATCCAGCGCAAGGGCTCGCCCATCGTCGCCATGGACGCCGAT
CCGCTGTTGCATCAGGCCTTGCGCCACTTGGCACCGGCCATCGAGGAAAGCGGCGGCGCCGTCGAGGTGGCGGAAGGCGG
CGAGGCCGTTCGGGTGATGGGCGATCCGGACCAGGTCATCCGGCTGTTCCAGAACCTGATCGGCAATGCCGTCAAGTACC
GGGCGCCGGACCGCGCGCCTCTGGTCAAGGTGTCGTGGCAGCGCACCGGCGGCGAGTGGGAGTGCGTGGTCGCCGATAAC
GGGATCGGTATAGATCCCCAGTATTTCGAGCGCATCTTCGGCATCTTCCAACGCCTGCATACCCCCGACGCCTACGCCGG
CACGGGCATCGGTCTGGCCATCTGCAAGAAGATCGTCGAACGCCATGGCGGGCGGATCTGGGTGGAGTCGGTGCCCGACC
AGGGCTCAGTCTTCCATTTCACCCTGCCGGCGGCTCAGCCCACATAG

Upstream 100 bases:

>100_bases
TGGCCGCCGCCGGGAGGAGCCGGGCGCCGGGCTCTTGCTGCTGGCCGCCGTCCTGGGCGGCTGGGGCTGCCTTCTCGCCG
GGCGGGGGCTGGGGGTGGCC

Downstream 100 bases:

>100_bases
GCGGAGATGTCGACCTCGTCGATCTGTTCCGGCTTCAAGAAGCGTTCGGCATAGCGGCGATAGACGCCCGAGGTCAGGAA
CAGGTCGAACAGGTCGGGAT

Product: sensor protein fixL

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MLGPIREFVSLEGGFALYYVLAGLGYVAILIALMLVDSDRLAAVLGEEVSRQAEALETQVERQVQAREDLRAILDNMPDI
FYRTDTEGRLLMVSRSVEGLLGYTVEEVLGLDSAFFHGSDDSRPQLVAALEAAGGSIIDYELRLRHKDGRILWASTSSRF
YLDAQGRRGGTEGVVRLIEERKRTELYIRENQALIQAMLDASSDAIMLFRPDGTLLAVNEVMAARFGRRATELTGSCLWD
MFPPDVAKAREEAVTRVVQTGEAIHYLDRRGDLYLDNSIYPVPGVDGVPDKVAVYSRDITAQTLAEQKVATYLAELERSN
AELEQFAYVASHDLREPLRMISSYLSLLERRYAPKLEGDGLEFLAFARDGAQRMDRLVLDLLDFSRIQRKGSPIVAMDAD
PLLHQALRHLAPAIEESGGAVEVAEGGEAVRVMGDPDQVIRLFQNLIGNAVKYRAPDRAPLVKVSWQRTGGEWECVVADN
GIGIDPQYFERIFGIFQRLHTPDAYAGTGIGLAICKKIVERHGGRIWVESVPDQGSVFHFTLPAAQPT

Sequences:

>Translated_548_residues
MLGPIREFVSLEGGFALYYVLAGLGYVAILIALMLVDSDRLAAVLGEEVSRQAEALETQVERQVQAREDLRAILDNMPDI
FYRTDTEGRLLMVSRSVEGLLGYTVEEVLGLDSAFFHGSDDSRPQLVAALEAAGGSIIDYELRLRHKDGRILWASTSSRF
YLDAQGRRGGTEGVVRLIEERKRTELYIRENQALIQAMLDASSDAIMLFRPDGTLLAVNEVMAARFGRRATELTGSCLWD
MFPPDVAKAREEAVTRVVQTGEAIHYLDRRGDLYLDNSIYPVPGVDGVPDKVAVYSRDITAQTLAEQKVATYLAELERSN
AELEQFAYVASHDLREPLRMISSYLSLLERRYAPKLEGDGLEFLAFARDGAQRMDRLVLDLLDFSRIQRKGSPIVAMDAD
PLLHQALRHLAPAIEESGGAVEVAEGGEAVRVMGDPDQVIRLFQNLIGNAVKYRAPDRAPLVKVSWQRTGGEWECVVADN
GIGIDPQYFERIFGIFQRLHTPDAYAGTGIGLAICKKIVERHGGRIWVESVPDQGSVFHFTLPAAQPT
>Mature_548_residues
MLGPIREFVSLEGGFALYYVLAGLGYVAILIALMLVDSDRLAAVLGEEVSRQAEALETQVERQVQAREDLRAILDNMPDI
FYRTDTEGRLLMVSRSVEGLLGYTVEEVLGLDSAFFHGSDDSRPQLVAALEAAGGSIIDYELRLRHKDGRILWASTSSRF
YLDAQGRRGGTEGVVRLIEERKRTELYIRENQALIQAMLDASSDAIMLFRPDGTLLAVNEVMAARFGRRATELTGSCLWD
MFPPDVAKAREEAVTRVVQTGEAIHYLDRRGDLYLDNSIYPVPGVDGVPDKVAVYSRDITAQTLAEQKVATYLAELERSN
AELEQFAYVASHDLREPLRMISSYLSLLERRYAPKLEGDGLEFLAFARDGAQRMDRLVLDLLDFSRIQRKGSPIVAMDAD
PLLHQALRHLAPAIEESGGAVEVAEGGEAVRVMGDPDQVIRLFQNLIGNAVKYRAPDRAPLVKVSWQRTGGEWECVVADN
GIGIDPQYFERIFGIFQRLHTPDAYAGTGIGLAICKKIVERHGGRIWVESVPDQGSVFHFTLPAAQPT

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=392, Percent_Identity=25.2551020408163, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1786600, Length=222, Percent_Identity=31.981981981982, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI145693157, Length=253, Percent_Identity=28.0632411067194, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI87081816, Length=238, Percent_Identity=28.9915966386555, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786912, Length=215, Percent_Identity=31.1627906976744, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788549, Length=361, Percent_Identity=24.3767313019391, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1789149, Length=280, Percent_Identity=25.3571428571429, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1790346, Length=233, Percent_Identity=28.3261802575107, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=27.1493212669683, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788393, Length=246, Percent_Identity=27.6422764227642, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788713, Length=231, Percent_Identity=25.1082251082251, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 60801; Mature: 60801

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGPIREFVSLEGGFALYYVLAGLGYVAILIALMLVDSDRLAAVLGEEVSRQAEALETQV
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ERQVQAREDLRAILDNMPDIFYRTDTEGRLLMVSRSVEGLLGYTVEEVLGLDSAFFHGSD
HHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHHCCCHHEECCCC
DSRPQLVAALEAAGGSIIDYELRLRHKDGRILWASTSSRFYLDAQGRRGGTEGVVRLIEE
CCCCHHHHHHHHCCCCEEEEEEEEEECCCEEEEEECCCEEEEECCCCCCCHHHHHHHHHH
RKRTELYIRENQALIQAMLDASSDAIMLFRPDGTLLAVNEVMAARFGRRATELTGSCLWD
HHHHEEEEECHHHHHHHHHCCCCCEEEEECCCCCEEEHHHHHHHHHCCHHHHHHHHHHHC
MFPPDVAKAREEAVTRVVQTGEAIHYLDRRGDLYLDNSIYPVPGVDGVPDKVAVYSRDIT
CCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHEECCCH
AQTLAEQKVATYLAELERSNAELEQFAYVASHDLREPLRMISSYLSLLERRYAPKLEGDG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
LEFLAFARDGAQRMDRLVLDLLDFSRIQRKGSPIVAMDADPLLHQALRHLAPAIEESGGA
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCCE
VEVAEGGEAVRVMGDPDQVIRLFQNLIGNAVKYRAPDRAPLVKVSWQRTGGEWECVVADN
EEEECCCCEEEEECCHHHHHHHHHHHHCCCEEECCCCCCCEEEEEEECCCCCEEEEEECC
GIGIDPQYFERIFGIFQRLHTPDAYAGTGIGLAICKKIVERHGGRIWVESVPDQGSVFHF
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEE
TLPAAQPT
ECCCCCCC
>Mature Secondary Structure
MLGPIREFVSLEGGFALYYVLAGLGYVAILIALMLVDSDRLAAVLGEEVSRQAEALETQV
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ERQVQAREDLRAILDNMPDIFYRTDTEGRLLMVSRSVEGLLGYTVEEVLGLDSAFFHGSD
HHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHHCCCHHEECCCC
DSRPQLVAALEAAGGSIIDYELRLRHKDGRILWASTSSRFYLDAQGRRGGTEGVVRLIEE
CCCCHHHHHHHHCCCCEEEEEEEEEECCCEEEEEECCCEEEEECCCCCCCHHHHHHHHHH
RKRTELYIRENQALIQAMLDASSDAIMLFRPDGTLLAVNEVMAARFGRRATELTGSCLWD
HHHHEEEEECHHHHHHHHHCCCCCEEEEECCCCCEEEHHHHHHHHHCCHHHHHHHHHHHC
MFPPDVAKAREEAVTRVVQTGEAIHYLDRRGDLYLDNSIYPVPGVDGVPDKVAVYSRDIT
CCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHEECCCH
AQTLAEQKVATYLAELERSNAELEQFAYVASHDLREPLRMISSYLSLLERRYAPKLEGDG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
LEFLAFARDGAQRMDRLVLDLLDFSRIQRKGSPIVAMDADPLLHQALRHLAPAIEESGGA
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCCE
VEVAEGGEAVRVMGDPDQVIRLFQNLIGNAVKYRAPDRAPLVKVSWQRTGGEWECVVADN
EEEECCCCEEEEECCHHHHHHHHHHHHCCCEEECCCCCCCEEEEEEECCCCCEEEEEECC
GIGIDPQYFERIFGIFQRLHTPDAYAGTGIGLAICKKIVERHGGRIWVESVPDQGSVFHF
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEE
TLPAAQPT
ECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]