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The map label for this gene is mrp [H]

Identifier: 83312586

GI number: 83312586

Start: 3833981

End: 3835153

Strand: Reverse

Name: mrp [H]

Synonym: amb3487

Alternate gene names: 83312586

Gene position: 3835153-3833981 (Counterclockwise)

Preceding gene: 83312587

Following gene: 83312584

Centisome position: 77.21

GC content: 65.64

Gene sequence:

>1173_bases
GTGCGCTTTGGCGGCACATACCCAACTAATTTACTGTGTCTTTACAGCGAAGAGGACAGCATGGCCGAGGTCACCGAACA
GCAGATCATCGAGGCGCTGAGCCGGATCATTGATCCTGACCGCAAGGCCGACATCGTCGGTCTCGGCATGGTGTCGGGTC
TGACGCTGAAGGGCGGCCACGTGGCCTTCGCCATCGAGGTGGACCCCCAACGCGGTCCCCATCTCGAGCCCCTGCGCAAG
GCGGCCGAGAAGGCGGTGCATGATCTGCCGGGCGTGCTGTCGGTGTCGGCGGTGCTGACCGCCGAGCGCAACACCCAGGG
CGGCCCCAAGGGCGCTCCCCAGGGCGGTCACGGCCATCAGGCGGAAAAGCCGCTGCTCCCCAACGTCAAGGCCATCGTCG
CCATCGCCTCGGGCAAGGGCGGCGTGGGCAAGTCGACCACGGCCACCAACATCGCCATGGCGCTGTCGCGCATGGGACTC
AAGGTCGGCCTGTTCGACGCCGATATCTTCGGGCCTTCCATGCCGCGCATGCTGGGCATCACCGGCGAGCCGGTCAGCCC
CGACGGCCAGACCATGATGCCCATGGAGAATTACGGCGTGAAGTGCATGTCCATGGGCTTCCTGGTGCCCGAGGACTCGC
CGATCATCTGGCGCGGCCCCATGGTCATGGGCGCCCTGGAGCAGCTTCTGCGCGACGTCCATTGGGGCGAGCTGGACGTG
ATGATCATCGACATGCCGCCCGGCACTGGCGATACCCAGCTGACCATGACCCAGCGGGTGCCGCTGACCGGCGCGGTGAT
CGTGTCGACCCCCCAGGACATCGCCCTGCTGGACGCCACCAAGGGCCTCAACATGTTCCGCAAGGTGGATGTGCCGGTGC
TCGGCATCATCGAGAACATGAGCTATTACATCTGCCCCAAATGTGGCGACGAGGCCCACATCTTCGGCCATGGCGGCGCC
AAGGCGGAAGCGGCGCGCCTGTCGGCCGACTTCCTGGGCGAGATCCCGCTGGACATCTCCATCCGCCAGACGGCGGACGC
GGGCGAGCCCATCGTCATCTCCAAGCCCAACAGCCCCCACGCCAAGGTCTATATGGAGATCGCCGCCCGGATCTGGGACA
AGGTCCAGGTCCTGCAAAGCAGCCGCAAGGGTCCGCGCATCGTCATGGAATAG

Upstream 100 bases:

>100_bases
GCGCAACGCGGGGCCGTTCACATTACGGGTTTTCAATATTGAAAATGGCCCGAAATCGGCTTTGCAAACCGGGCGGCGCC
CCCTATATGAGAAGACGCTT

Downstream 100 bases:

>100_bases
GGGGGCTATCCCCCCGACGCCGGCCTCGGATGGGCGAGGTCGGTCATGACGCCCGGTCCGTTGACCAGCGAGAAGCCCGC
CTTGATCACGTCGGTGATCA

Product: chromosome partitioning ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MRFGGTYPTNLLCLYSEEDSMAEVTEQQIIEALSRIIDPDRKADIVGLGMVSGLTLKGGHVAFAIEVDPQRGPHLEPLRK
AAEKAVHDLPGVLSVSAVLTAERNTQGGPKGAPQGGHGHQAEKPLLPNVKAIVAIASGKGGVGKSTTATNIAMALSRMGL
KVGLFDADIFGPSMPRMLGITGEPVSPDGQTMMPMENYGVKCMSMGFLVPEDSPIIWRGPMVMGALEQLLRDVHWGELDV
MIIDMPPGTGDTQLTMTQRVPLTGAVIVSTPQDIALLDATKGLNMFRKVDVPVLGIIENMSYYICPKCGDEAHIFGHGGA
KAEAARLSADFLGEIPLDISIRQTADAGEPIVISKPNSPHAKVYMEIAARIWDKVQVLQSSRKGPRIVME

Sequences:

>Translated_390_residues
MRFGGTYPTNLLCLYSEEDSMAEVTEQQIIEALSRIIDPDRKADIVGLGMVSGLTLKGGHVAFAIEVDPQRGPHLEPLRK
AAEKAVHDLPGVLSVSAVLTAERNTQGGPKGAPQGGHGHQAEKPLLPNVKAIVAIASGKGGVGKSTTATNIAMALSRMGL
KVGLFDADIFGPSMPRMLGITGEPVSPDGQTMMPMENYGVKCMSMGFLVPEDSPIIWRGPMVMGALEQLLRDVHWGELDV
MIIDMPPGTGDTQLTMTQRVPLTGAVIVSTPQDIALLDATKGLNMFRKVDVPVLGIIENMSYYICPKCGDEAHIFGHGGA
KAEAARLSADFLGEIPLDISIRQTADAGEPIVISKPNSPHAKVYMEIAARIWDKVQVLQSSRKGPRIVME
>Mature_390_residues
MRFGGTYPTNLLCLYSEEDSMAEVTEQQIIEALSRIIDPDRKADIVGLGMVSGLTLKGGHVAFAIEVDPQRGPHLEPLRK
AAEKAVHDLPGVLSVSAVLTAERNTQGGPKGAPQGGHGHQAEKPLLPNVKAIVAIASGKGGVGKSTTATNIAMALSRMGL
KVGLFDADIFGPSMPRMLGITGEPVSPDGQTMMPMENYGVKCMSMGFLVPEDSPIIWRGPMVMGALEQLLRDVHWGELDV
MIIDMPPGTGDTQLTMTQRVPLTGAVIVSTPQDIALLDATKGLNMFRKVDVPVLGIIENMSYYICPKCGDEAHIFGHGGA
KAEAARLSADFLGEIPLDISIRQTADAGEPIVISKPNSPHAKVYMEIAARIWDKVQVLQSSRKGPRIVME

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=272, Percent_Identity=52.2058823529412, Blast_Score=292, Evalue=4e-79,
Organism=Homo sapiens, GI118572611, Length=318, Percent_Identity=38.6792452830189, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI6912540, Length=261, Percent_Identity=38.6973180076628, Blast_Score=186, Evalue=3e-47,
Organism=Escherichia coli, GI87082045, Length=251, Percent_Identity=52.5896414342629, Blast_Score=273, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI25143050, Length=257, Percent_Identity=38.9105058365759, Blast_Score=183, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6322188, Length=222, Percent_Identity=40.990990990991, Blast_Score=187, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6321347, Length=258, Percent_Identity=37.984496124031, Blast_Score=178, Evalue=1e-45,
Organism=Drosophila melanogaster, GI221511043, Length=254, Percent_Identity=42.5196850393701, Blast_Score=238, Evalue=5e-63,
Organism=Drosophila melanogaster, GI24667611, Length=254, Percent_Identity=38.1889763779528, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI19921440, Length=239, Percent_Identity=40.1673640167364, Blast_Score=159, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR015223
- InterPro:   IPR002744
- InterPro:   IPR000808 [H]

Pfam domain/function: PF01883 DUF59; PF09140 MipZ; PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 41674; Mature: 41674

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFGGTYPTNLLCLYSEEDSMAEVTEQQIIEALSRIIDPDRKADIVGLGMVSGLTLKGGH
CCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHCCEEEECCE
VAFAIEVDPQRGPHLEPLRKAAEKAVHDLPGVLSVSAVLTAERNTQGGPKGAPQGGHGHQ
EEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHEEEEEEEECCCCCCCCCCCCCCCCCCC
AEKPLLPNVKAIVAIASGKGGVGKSTTATNIAMALSRMGLKVGLFDADIFGPSMPRMLGI
CCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEEECHHCCCCCCCEECC
TGEPVSPDGQTMMPMENYGVKCMSMGFLVPEDSPIIWRGPMVMGALEQLLRDVHWGELDV
CCCCCCCCCCEECCHHHCCCEEEEEEEECCCCCCEEEECCHHHHHHHHHHHHCCCCCEEE
MIIDMPPGTGDTQLTMTQRVPLTGAVIVSTPQDIALLDATKGLNMFRKVDVPVLGIIENM
EEEECCCCCCCCEEEEEECCCCCEEEEEECCCCEEEEECCCCCCHHHHCCCCCEEHHHCC
SYYICPKCGDEAHIFGHGGAKAEAARLSADFLGEIPLDISIRQTADAGEPIVISKPNSPH
CEEECCCCCCCCEEEECCCCCCHHHHHCHHHHCCCCCEEEEECCCCCCCCEEEECCCCCH
AKVYMEIAARIWDKVQVLQSSRKGPRIVME
HHHHHHHHHHHHHHHHHHHHCCCCCEEECC
>Mature Secondary Structure
MRFGGTYPTNLLCLYSEEDSMAEVTEQQIIEALSRIIDPDRKADIVGLGMVSGLTLKGGH
CCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHCCEEEECCE
VAFAIEVDPQRGPHLEPLRKAAEKAVHDLPGVLSVSAVLTAERNTQGGPKGAPQGGHGHQ
EEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHEEEEEEEECCCCCCCCCCCCCCCCCCC
AEKPLLPNVKAIVAIASGKGGVGKSTTATNIAMALSRMGLKVGLFDADIFGPSMPRMLGI
CCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEEECHHCCCCCCCEECC
TGEPVSPDGQTMMPMENYGVKCMSMGFLVPEDSPIIWRGPMVMGALEQLLRDVHWGELDV
CCCCCCCCCCEECCHHHCCCEEEEEEEECCCCCCEEEECCHHHHHHHHHHHHCCCCCEEE
MIIDMPPGTGDTQLTMTQRVPLTGAVIVSTPQDIALLDATKGLNMFRKVDVPVLGIIENM
EEEECCCCCCCCEEEEEECCCCCEEEEEECCCCEEEEECCCCCCHHHHCCCCCEEHHHCC
SYYICPKCGDEAHIFGHGGAKAEAARLSADFLGEIPLDISIRQTADAGEPIVISKPNSPH
CEEECCCCCCCCEEEECCCCCCHHHHHCHHHHCCCCCEEEEECCCCCCCCEEEECCCCCH
AKVYMEIAARIWDKVQVLQSSRKGPRIVME
HHHHHHHHHHHHHHHHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]