Click here to switch to the map view.

The map label for this gene is hscB [H]

Identifier: 83312124

GI number: 83312124

Start: 3268551

End: 3269177

Strand: Reverse

Name: hscB [H]

Synonym: amb3025

Alternate gene names: 83312124

Gene position: 3269177-3268551 (Counterclockwise)

Preceding gene: 83312125

Following gene: 83312123

Centisome position: 65.82

GC content: 64.75

Gene sequence:

>627_bases
ATGAACGCCCCCGCCGCCGCCCAGATCGTTTCCTGTTGGTCCTGCAAGGGGCCGGTGGCGACGCGTGCCCTGTTCTGTTC
GGTGTGTGGCGCCGTGCAGGGGCCGGGCAATATCGACCACTTCTCGCGCCTTGGCATCCCGCCGTCCTTCGACCTGGACC
TGGACGCCCTGCAGCACCAGTATTTCGGCTTCCAGAAACGTCTGCATCCCGACCGCTTCGCCTCCAAGTCCCCCAAGGAG
AAGGCGCTGTCGCAATCCCAGGCCACGTCACTGAACGAGGCCTACGAGACGCTGAAGGATCCCCTGAAGCGCGCCGCCTA
TCTTCTGAACCACCTGGGCCATCCGGTGGACCTTACCGCCTGCGGCACCATCAACGACCGCGAGTTGCTGATGGAGCAGA
TGGAAAAGCGCGAAGCCCTGGCCGAGGCCTCCACGCCGGAGGAGATCGCCAAGCTGGCCATGGCGGCGGAATCCGAGGTC
ATCGCCTGCCAGTGCCACATCTCGGCCGCCATCAACGCCGCCGATCTGGAAGAGGCGGGTCACCTGACCATCCGCCTCAA
ATATCTCGCCAAGCTGGCCGAAGAGGCCCGCGCCAAGAAGACCCGTGCCCTCAGACTGCCCTCTTAA

Upstream 100 bases:

>100_bases
GTCTTCAAGAACCCCAACGAAAAGGGCCGGTGCGGCTGCGGCGAATCCTTCCACGTCTGAGCCCCGCCCCGTTAAAGTGA
AGAAGGAACCGGAGAGGACG

Downstream 100 bases:

>100_bases
GACAAGGTTGCCCTAAGCATGCTGCTGCAGCTCCATGAACCCGGCGAGAGCCCGGCACCTCACGAATCCGAACGCGGCCT
GGCGGTCGGCATTGACCTGG

Product: DnaJ-domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MNAPAAAQIVSCWSCKGPVATRALFCSVCGAVQGPGNIDHFSRLGIPPSFDLDLDALQHQYFGFQKRLHPDRFASKSPKE
KALSQSQATSLNEAYETLKDPLKRAAYLLNHLGHPVDLTACGTINDRELLMEQMEKREALAEASTPEEIAKLAMAAESEV
IACQCHISAAINAADLEEAGHLTIRLKYLAKLAEEARAKKTRALRLPS

Sequences:

>Translated_208_residues
MNAPAAAQIVSCWSCKGPVATRALFCSVCGAVQGPGNIDHFSRLGIPPSFDLDLDALQHQYFGFQKRLHPDRFASKSPKE
KALSQSQATSLNEAYETLKDPLKRAAYLLNHLGHPVDLTACGTINDRELLMEQMEKREALAEASTPEEIAKLAMAAESEV
IACQCHISAAINAADLEEAGHLTIRLKYLAKLAEEARAKKTRALRLPS
>Mature_208_residues
MNAPAAAQIVSCWSCKGPVATRALFCSVCGAVQGPGNIDHFSRLGIPPSFDLDLDALQHQYFGFQKRLHPDRFASKSPKE
KALSQSQATSLNEAYETLKDPLKRAAYLLNHLGHPVDLTACGTINDRELLMEQMEKREALAEASTPEEIAKLAMAAESEV
IACQCHISAAINAADLEEAGHLTIRLKYLAKLAEEARAKKTRALRLPS

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI50301234, Length=203, Percent_Identity=33.9901477832512, Blast_Score=111, Evalue=4e-25,
Organism=Escherichia coli, GI1788876, Length=116, Percent_Identity=38.7931034482759, Blast_Score=82, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17541320, Length=142, Percent_Identity=30.9859154929577, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161084223, Length=197, Percent_Identity=27.4111675126904, Blast_Score=91, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640
- InterPro:   IPR015609 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 22668; Mature: 22668

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPAAAQIVSCWSCKGPVATRALFCSVCGAVQGPGNIDHFSRLGIPPSFDLDLDALQHQ
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCHHHHHHH
YFGFQKRLHPDRFASKSPKEKALSQSQATSLNEAYETLKDPLKRAAYLLNHLGHPVDLTA
HHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
CGTINDRELLMEQMEKREALAEASTPEEIAKLAMAAESEVIACQCHISAAINAADLEEAG
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEEHHHHHCCHHHHHHCC
HLTIRLKYLAKLAEEARAKKTRALRLPS
CCEEHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNAPAAAQIVSCWSCKGPVATRALFCSVCGAVQGPGNIDHFSRLGIPPSFDLDLDALQHQ
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCHHHHHHH
YFGFQKRLHPDRFASKSPKEKALSQSQATSLNEAYETLKDPLKRAAYLLNHLGHPVDLTA
HHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
CGTINDRELLMEQMEKREALAEASTPEEIAKLAMAAESEVIACQCHISAAINAADLEEAG
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEEHHHHHCCHHHHHHCC
HLTIRLKYLAKLAEEARAKKTRALRLPS
CCEEHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA