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The map label for this gene is 83311796

Identifier: 83311796

GI number: 83311796

Start: 2889976

End: 2890398

Strand: Reverse

Name: 83311796

Synonym: amb2697

Alternate gene names: NA

Gene position: 2890398-2889976 (Counterclockwise)

Preceding gene: 83311797

Following gene: 83311795

Centisome position: 58.19

GC content: 67.38

Gene sequence:

>423_bases
ATGACCATGGCCTGGTATGACTACTTCATGGGCTTCGCCAAGCACGCCGCCAGCAAGTCCAAGGACCCCAGCACCCAGGT
GGGCGCCGTGGCGGTGGGACCGGACGGCGAGATCCGCGCCACCGGCTATAACGGCCTGCCGCGTGGGGTCGAGGACCGGC
CCGAACGCATGGAGCGCCCGGCCAAGTATCTGTGGACCTCGCATGCCGAGGAGAATCTGGTGGCTCATGCCGCCCGGGTG
GGGGTCAGCCTCAAGGGCTGCACGGTCTATGTCACCCATTACCCCTGTTCGCGCTGCGCCCGCTCGCTGATCCAGGCCGG
GGTGGCCGAGATCCATGTGGGCGACGGCACCACCTCCATGCCCGCCGAGGAATTCGACACCGCCCGGGTGATGTTCGAGG
AATCCGGCGTCAAGGTGGGCTGA

Upstream 100 bases:

>100_bases
TCACCGACGAGGGCCGCACCCTGGTCCGCGCCGTCTGCGCCGCCTTCGACCGCTACCTCAAGGCGGGCGAACAGCGACAT
TCGAAGGCGGTCTGAGCATC

Downstream 100 bases:

>100_bases
GCCCACTCTGGCCACCCACCTCGGGTGGCCTGCCCCTACCCAAGTAATTTCGCACACTCCCCCTCCGGGTGTTCCGCCGG
CCGGGGGGCATGGCCATAGT

Product: deoxycytidylate deaminase

Products: dUMP; NH3

Alternate protein names: NA

Number of amino acids: Translated: 140; Mature: 139

Protein sequence:

>140_residues
MTMAWYDYFMGFAKHAASKSKDPSTQVGAVAVGPDGEIRATGYNGLPRGVEDRPERMERPAKYLWTSHAEENLVAHAARV
GVSLKGCTVYVTHYPCSRCARSLIQAGVAEIHVGDGTTSMPAEEFDTARVMFEESGVKVG

Sequences:

>Translated_140_residues
MTMAWYDYFMGFAKHAASKSKDPSTQVGAVAVGPDGEIRATGYNGLPRGVEDRPERMERPAKYLWTSHAEENLVAHAARV
GVSLKGCTVYVTHYPCSRCARSLIQAGVAEIHVGDGTTSMPAEEFDTARVMFEESGVKVG
>Mature_139_residues
TMAWYDYFMGFAKHAASKSKDPSTQVGAVAVGPDGEIRATGYNGLPRGVEDRPERMERPAKYLWTSHAEENLVAHAARVG
VSLKGCTVYVTHYPCSRCARSLIQAGVAEIHVGDGTTSMPAEEFDTARVMFEESGVKVG

Specific function: Unknown

COG id: COG2131

COG function: function code F; Deoxycytidylate deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI61742819, Length=142, Percent_Identity=37.3239436619718, Blast_Score=97, Evalue=3e-21,
Organism=Homo sapiens, GI61742821, Length=142, Percent_Identity=37.3239436619718, Blast_Score=97, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17557019, Length=134, Percent_Identity=36.5671641791045, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24667298, Length=148, Percent_Identity=33.1081081081081, Blast_Score=86, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24667302, Length=148, Percent_Identity=33.1081081081081, Blast_Score=86, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR015517
- InterPro:   IPR016193
- InterPro:   IPR016473 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.12

Molecular weight: Translated: 15184; Mature: 15053

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMAWYDYFMGFAKHAASKSKDPSTQVGAVAVGPDGEIRATGYNGLPRGVEDRPERMERP
CCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEECCCCCCCCCCCCCHHHHHCH
AKYLWTSHAEENLVAHAARVGVSLKGCTVYVTHYPCSRCARSLIQAGVAEIHVGDGTTSM
HHHHHHCCCHHHHHHHHHHHCEEECCCEEEEEECCHHHHHHHHHHCCHHEEEECCCCCCC
PAEEFDTARVMFEESGVKVG
CHHHHHHHHEEECCCCCCCC
>Mature Secondary Structure 
TMAWYDYFMGFAKHAASKSKDPSTQVGAVAVGPDGEIRATGYNGLPRGVEDRPERMERP
CCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEECCCCCCCCCCCCCHHHHHCH
AKYLWTSHAEENLVAHAARVGVSLKGCTVYVTHYPCSRCARSLIQAGVAEIHVGDGTTSM
HHHHHHCCCHHHHHHHHHHHCEEECCCEEEEEECCHHHHHHHHHHCCHHEEEECCCCCCC
PAEEFDTARVMFEESGVKVG
CHHHHHHHHEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dCMP; H2O

Specific reaction: dCMP + H2O = dUMP + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8329441 [H]